A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation

Oncotarget

Volumn 6, Issue 30, 2015, Pages 28646-28660

  Sahni, Hemant ^a   Ross, Susan ^a   Barbarulo, Alessandro ^a   Solanki, Anisha ^a   Lau, Ching In ^a   Furmanski, Anna ^a   Saldaña, José Ignacio ^a   Ono, Masahiro ^a   Hubank, Mike ^a   Barenco, Martino ^a   Crompton, Tessa ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

DP; Foetal thymic organ cultures; Genome wide transcriptional modelling; Immune response; Immunity; Immunology Section; Pre TCR; Thymus

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; RAG1 PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTOME; GENETIC MARKER; HOMEODOMAIN PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN PRECURSOR; RAG-1 PROTEIN; RNA;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; FETUS; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOME WIDE TRANSCRIPTIONAL MODEL; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRE TCR SIGNALING; RNA DEGRADATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; TIME SERIES ANALYSIS; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CELL CULTURE; CLUSTER ANALYSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETIC MARKER; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PROCEDURES; RNA STABILITY; TIME FACTOR;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC MARKERS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HOMEODOMAIN PROTEINS; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, GENETIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PROTEIN PRECURSORS; RECEPTORS, ANTIGEN, T-CELL; RNA; RNA STABILITY; SIGNAL TRANSDUCTION; THYMOCYTES; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84945162471     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5796     Document Type: Article

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