β-Catenin induces T-cell transformation by promoting genomic instability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 1, 2014, Pages 391-396

  Dose, Marei ^a   Emmanuel, Akinola Olumide ^a   Chaumeil, Julie ^b   Zhang, Jiangwen ^c   Sun, Tianjiao ^a   Germar, Kristine ^a   Aghajani, Katayoun ^a   Davis, Elizabeth M ^d   Keerthivasan, Shilpa ^a   Bredemeyer, Andrea L ^e   Sleckman, Barry P ^e   Rosen, Steven T ^f   Skok, Jane A ^b   Le Beau, Michelle M ^d   Georgopoulos, Katia ^g   Gounari, Fotini ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD UNIVERSITY   (United States)

^d SECTION OF HEMATOLOGY ONCOLOGY   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f NORTHWESTERN UNIVERSITY   (United States)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Beta catenin Tcf 1; Ctnnb1; DNA recombination Tcf7

Indexed keywords

BETA CATENIN; HISTONE H3; MYC PROTEIN; RAG2 PROTEIN; TRANSCRIPTION FACTOR 7;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; DNA RECOMBINATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENHANCER REGION; GENE EXPRESSION; GENOME; GENOMIC INSTABILITY; LYMPHOCYTE TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T CELL LYMPHOMA; T LYMPHOCYTE; THYMOCYTE; TRANSCRIPTION INITIATION;

BETA-CATENIN/TCF-1; CTNNB1; DNA RECOMBINATION TCF7;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BETA CATENIN; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DNA BREAKS, DOUBLE-STRANDED; DNA METHYLATION; DNA REPAIR; GENES, RAG-1; GENOMIC INSTABILITY; HISTONES; LYMPHOCYTE ACTIVATION; LYMPHOMA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; RECOMBINATION, GENETIC; T CELL TRANSCRIPTION FACTOR 1; T-LYMPHOCYTES; THYMOCYTES; TRANSLOCATION, GENETIC;

EID: 84891934864     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1315752111     Document Type: Article

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