Porcine reproductive and respiratory syndrome virus 3C protease cleaves the mitochondrial antiviral signalling complex to antagonize IFN-β expression

Journal of General Virology

Volumn 96, Issue 10, 2015, Pages 3049-3058

  Dong, Jianming ^a,b   Xu, Shangen ^a,b   Wang, Jing ^a,b   Luo, Rui ^a,b   Wang, Dang ^a,b   Xiao, Shaobo ^a,b   Fang, Liurong ^a,b   Chen, Huanchun ^a,b   Jiang, Yunbo ^a,b  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^b State Key Laboratory of Agricultural Microbiology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYSTEINE PROTEINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; MITOCHONDRIAL ANTIVIRAL SIGNALLING PROTEIN; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS 3C PROTEASE; PROTEINASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; 3C PROTEASES; CASPASE; MITOCHONDRIAL PROTEIN; PROTEASOME; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; ENZYME ACTIVITY; EXPRESSION VECTOR; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; POINT MUTATION; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; HYDROLYSIS; IMMUNE EVASION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CASPASES; CYSTEINE ENDOPEPTIDASES; HYDROLYSIS; IMMUNE EVASION; INTERFERON-BETA; MITOCHONDRIAL PROTEINS; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; PROTEASOME ENDOPEPTIDASE COMPLEX; VIRAL PROTEINS;

EID: 84944810920     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/jgv.0.000257     Document Type: Article

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