-
6
-
-
25144458985
-
Topics in pediatric leukemia-acute lymphoblastic leukemia
-
Esparza SD, Sakamoto KM. Topics in pediatric leukemia-acute lymphoblastic leukemia. MedGenMed 2005;7:23.
-
(2005)
MedGenMed
, vol.7
, pp. 23
-
-
Esparza, S.D.1
Sakamoto, K.M.2
-
7
-
-
0035412104
-
Pattern of malignant disorders in individuals with Down's syndrome
-
Hasle H. Pattern of malignant disorders in individuals with Down's syndrome. Lancet Oncol 2001;2:429-436.
-
(2001)
Lancet Oncol
, vol.2
, pp. 429-436
-
-
Hasle, H.1
-
8
-
-
33750547601
-
Down syndrome and acute lymphoblastic leukaemia
-
Whitlock JA. Down syndrome and acute lymphoblastic leukaemia. Br J Haematol 2006;135:595-602.
-
(2006)
Br J Haematol
, vol.135
, pp. 595-602
-
-
Whitlock, J.A.1
-
9
-
-
0027974256
-
Neurofibromatosis and childhood leukaemia/lymphoma: A population-based UKCCSG study
-
Stiller CA, Chessells JM, Fitchett M. Neurofibromatosis and childhood leukaemia/lymphoma: a population-based UKCCSG study. Br J Cancer 1994;70:969-972.
-
(1994)
Br J Cancer
, vol.70
, pp. 969-972
-
-
Stiller, C.A.1
Chessells, J.M.2
Fitchett, M.3
-
11
-
-
0028389468
-
Acute lymphoblastic leukemia associated with Klinefelter syndrome
-
Gurgey A, Kara A, Tuncer M, et al. Acute lymphoblastic leukemia associated with Klinefelter syndrome. Pediatr Hematol Oncol 1994;11:227-229.
-
(1994)
Pediatr Hematol Oncol
, vol.11
, pp. 227-229
-
-
Gurgey, A.1
Kara, A.2
Tuncer, M.3
-
12
-
-
5044232680
-
Acute lymphoblastic leukemia and Klinefelter syndrome in children: Two cases and review of the literature
-
Machatschek JN, Schrauder A, Helm F, et al. Acute lymphoblastic leukemia and Klinefelter syndrome in children: two cases and review of the literature. Pediatr Hematol Oncol 2004;21:621-626.
-
(2004)
Pediatr Hematol Oncol
, vol.21
, pp. 621-626
-
-
Machatschek, J.N.1
Schrauder, A.2
Helm, F.3
-
13
-
-
84872745645
-
Successful treatment of fanconi anemia and T-cell acute lymphoblastic leukemia
-
Flatt T, Neville K, Lewing K, Dalal J. Successful treatment of fanconi anemia and T-cell acute lymphoblastic leukemia. Case Rep Hematol 2012;2012:396395.
-
(2012)
Case Rep Hematol
, vol.2012
-
-
Flatt, T.1
Neville, K.2
Lewing, K.3
Dalal, J.4
-
14
-
-
0028366291
-
Acute lymphoblastic leukemia in Fanconi's anemia
-
Yetgin S, Tuncer M, Guler E, et al. Acute lymphoblastic leukemia in Fanconi's anemia. Am J Hematol 1994;45:94.
-
(1994)
Am J Hematol
, vol.45
, pp. 94
-
-
Yetgin, S.1
Tuncer, M.2
Guler, E.3
-
16
-
-
0019828777
-
The occurrence of leukemia in patients with the Shwachman syndrome
-
Woods WG, Roloff JS, Lukens JN, Krivit W. The occurrence of leukemia in patients with the Shwachman syndrome. J Pediatr 1981;99:425-428.
-
(1981)
J Pediatr
, vol.99
, pp. 425-428
-
-
Woods, W.G.1
Roloff, J.S.2
Lukens, J.N.3
Krivit, W.4
-
17
-
-
0026349029
-
Bloom's syndrome: The German experience
-
Passarge E. Bloom's syndrome: the German experience. Ann Genet 1991;34:179-197.
-
(1991)
Ann Genet
, vol.34
, pp. 179-197
-
-
Passarge, E.1
-
19
-
-
84926460567
-
Survival improvement by decade of patients aged 0-14 years with acute lymphoblastic leukemia: A SEER analysis
-
Ma H, Sun H, Sun X. Survival improvement by decade of patients aged 0-14 years with acute lymphoblastic leukemia: a SEER analysis. Sci Rep 2014;4:4227.
-
(2014)
Sci Rep
, vol.4
, pp. 4227
-
-
Ma, H.1
Sun, H.2
Sun, X.3
-
20
-
-
84880877717
-
Monosomal karyotype in Philadelphia chromosome-negative acute lymphoblastic leukemia
-
Kenderian SS, Al-Kali A, Gangat N, et al. Monosomal karyotype in Philadelphia chromosome-negative acute lymphoblastic leukemia. Blood Cancer J 2013;3:e122.
-
(2013)
Blood Cancer J
, vol.3
, pp. e122
-
-
Kenderian, S.S.1
Al-Kali, A.2
Gangat, N.3
-
21
-
-
84899965720
-
Survival of Adults with Acute Lymphoblastic Leukemia in Germany and the United States
-
Pulte D, Jansen L, Gondos A, et al. Survival of Adults with Acute Lymphoblastic Leukemia in Germany and the United States. PLoS ONE 2014;9:e85554.
-
(2014)
PLoS ONE
, vol.9
-
-
Pulte, D.1
Jansen, L.2
Gondos, A.3
-
22
-
-
79955030135
-
Adolescents and young adults with acute lymphoblastic leukemia
-
Stock W. Adolescents and young adults with acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program 2010;2010:21-29.
-
(2010)
Hematology Am Soc Hematol Educ Program
, vol.2010
, pp. 21-29
-
-
Stock, W.1
-
23
-
-
77149133679
-
Adult acute lymphoblastic leukemia: Concepts and strategies
-
Faderl S, O'Brien S, Pui CH, et al. Adult acute lymphoblastic leukemia: concepts and strategies. Cancer 2010;116:1165-1176.
-
(2010)
Cancer
, vol.116
, pp. 1165-1176
-
-
Faderl, S.1
O'Brien, S.2
Pui, C.H.3
-
24
-
-
70349657746
-
Blymphoblastic leukaemia/lymphoma not otherwise specified
-
Swerdlow SH Campo E Harris NL et al. eds., (ed 4th). Lyon: IARC
-
Borowitz MJ, Chan JKC. B lymphoblastic leukaemia/lymphoma, not otherwise specified In: Swerdlow SH, Campo E, Harris NL, et al., eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (ed 4th). Lyon: IARC; 2008:168-170.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
, pp. 168-170
-
-
Borowitz, M.J.1
Chan, J.K.C.2
-
25
-
-
70349657746
-
Tlymphoblastic leukaemia/lymphoma
-
Swerdlow SH, Campo E, Harris NL, et al., eds., (ed 4th). Lyon: IARC
-
Borowitz MJ, Chan JKC. T lymphoblastic leukaemia/lymphoma. In: Swerdlow SH, Campo E, Harris NL, et al., eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (ed 4th). Lyon: IARC; 2008 176-178.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
, pp. 176-178
-
-
Borowitz, M.J.1
Chan, J.K.C.2
-
27
-
-
4444268220
-
Outcome with the hyper-CVAD regimens in lymphoblastic lymphoma
-
Thomas DA, O'Brien S, Cortes J, et al. Outcome with the hyper-CVAD regimens in lymphoblastic lymphoma. Blood 2004;104:1624-1630.
-
(2004)
Blood
, vol.104
, pp. 1624-1630
-
-
Thomas, D.A.1
O'Brien, S.2
Cortes, J.3
-
28
-
-
70349657746
-
B lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities
-
Swerdlow SH, Campo E, Harris NL, et al., eds., (ed 4th). Lyon: IARC
-
Borowitz MJ, Chan JKC. B lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities. In: Swerdlow SH, Campo E, Harris NL, et al., eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (ed 4th). Lyon: IARC; 2008:171-175.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
, pp. 171-175
-
-
Borowitz, M.J.1
Chan, J.K.C.2
-
29
-
-
79952095577
-
Modern therapy of acute lymphoblastic leukemia
-
Bassan R, Hoelzer D. Modern therapy of acute lymphoblastic leukemia. J Clin Oncol 2011;29:532-543.
-
(2011)
J Clin Oncol
, vol.29
, pp. 532-543
-
-
Bassan, R.1
Hoelzer, D.2
-
33
-
-
67650594764
-
Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia
-
Thomas DA, O'Brien S, Jorgensen JL, et al. Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia. Blood 2009;113:6330-6337.
-
(2009)
Blood
, vol.113
, pp. 6330-6337
-
-
Thomas, D.A.1
O'Brien, S.2
Jorgensen, J.L.3
-
34
-
-
58749095816
-
Early T-cell precursor leukaemia: A subtype of very high-risk acute lymphoblastic leukaemia
-
Coustan-Smith E, Mullighan CG, Onciu M, et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol 2009;10:147-156.
-
(2009)
Lancet Oncol
, vol.10
, pp. 147-156
-
-
Coustan-Smith, E.1
Mullighan, C.G.2
Onciu, M.3
-
35
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
Zhang J, Ding L, Holmfeldt L, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 2012;481:157-163.
-
(2012)
Nature
, vol.481
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
-
36
-
-
34247399924
-
Superiority of allogeneic hematopoietic stem-cell transplantation compared with chemotherapy alone in high-risk childhood T-cell acute lymphoblastic leukemia: Results from ALL-BFM 90 and 95
-
Schrauder A, Reiter A, Gadner H, et al. Superiority of allogeneic hematopoietic stem-cell transplantation compared with chemotherapy alone in high-risk childhood T-cell acute lymphoblastic leukemia: results from ALL-BFM 90 and 95. J Clin Oncol 2006;24:5742-5749.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5742-5749
-
-
Schrauder, A.1
Reiter, A.2
Gadner, H.3
-
37
-
-
27244440324
-
Molecular genetics of acute lymphoblastic leukemia
-
Armstrong SA, Look AT. Molecular genetics of acute lymphoblastic leukemia. J Clin Oncol 2005;23:6306-6315.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6306-6315
-
-
Armstrong, S.A.1
Look, A.T.2
-
38
-
-
75649092322
-
A population-based cytogenetic study of adults with acute lymphoblastic leukemia
-
Moorman AV, Chilton L, Wilkinson J, et al. A population-based cytogenetic study of adults with acute lymphoblastic leukemia. Blood 2010;115:206-214.
-
(2010)
Blood
, vol.115
, pp. 206-214
-
-
Moorman, A.V.1
Chilton, L.2
Wilkinson, J.3
-
39
-
-
67651167100
-
Treatment of acute lymphoblastic leukemia in children and adolescents: Peaks and pitfalls
-
Seibel NL. Treatment of acute lymphoblastic leukemia in children and adolescents: peaks and pitfalls. Hematology Am Soc Hematol Educ Program 2008:374-380.
-
(2008)
Hematology Am Soc Hematol Educ Program
, pp. 374-380
-
-
Seibel, N.L.1
-
40
-
-
50949089832
-
Patients' age and BCR-ABL frequency in adult B-precursor ALL: A retrospective analysis from the GMALL study group
-
Burmeister T, Schwartz S, Bartram CR, et al. Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group. Blood 2008;112:918-919.
-
(2008)
Blood
, vol.112
, pp. 918-919
-
-
Burmeister, T.1
Schwartz, S.2
Bartram, C.R.3
-
41
-
-
0036493694
-
Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: A prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis
-
Gleissner B, Gokbuget N, Bartram CR, et al. Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis. Blood 2002;99:1536-1543.
-
(2002)
Blood
, vol.99
, pp. 1536-1543
-
-
Gleissner, B.1
Gokbuget, N.2
Bartram, C.R.3
-
42
-
-
30444437486
-
Treatment of acute lymphoblastic leukemia
-
Pui C-H, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med 2006;354:166-178.
-
(2006)
N Engl J Med
, vol.354
, pp. 166-178
-
-
Pui, C.-H.1
Evans, W.E.2
-
43
-
-
0034611661
-
Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Arico M, Valsecchi MG, Camitta B, et al. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N Engl J Med 2000;342:998-1006.
-
(2000)
N Engl J Med
, vol.342
, pp. 998-1006
-
-
Arico, M.1
Valsecchi, M.G.2
Camitta, B.3
-
44
-
-
58749097408
-
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: A genome-wide classification study
-
Den Boer ML, van Slegtenhorst M, De Menezes RX, et al. A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. Lancet Oncol 2009;10:125-134.
-
(2009)
Lancet Oncol
, vol.10
, pp. 125-134
-
-
Den Boer, M.L.1
Van Slegtenhorst, M.2
De Menezes, R.X.3
-
45
-
-
58749109707
-
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
-
Mullighan CG, Su X, Zhang J, et al. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med 2009;360:470-480.
-
(2009)
N Engl J Med
, vol.360
, pp. 470-480
-
-
Mullighan, C.G.1
Su, X.2
Zhang, J.3
-
46
-
-
84865118132
-
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
-
Roberts KG, Morin RD, Zhang J, et al. Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell 2012;22:153-166.
-
(2012)
Cancer Cell
, vol.22
, pp. 153-166
-
-
Roberts, K.G.1
Morin, R.D.2
Zhang, J.3
-
47
-
-
84907080295
-
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
-
Roberts KG, Li Y, Payne-Turner D, et al. Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med 2014;371:1005-1015.
-
(2014)
N Engl J Med
, vol.371
, pp. 1005-1015
-
-
Roberts, K.G.1
Li, Y.2
Payne-Turner, D.3
-
48
-
-
33846892770
-
Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: A combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG)
-
Schultz KR, Pullen DJ, Sather HN, et al. Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG). Blood 2007;109:926-935.
-
(2007)
Blood
, vol.109
, pp. 926-935
-
-
Schultz, K.R.1
Pullen, D.J.2
Sather, H.N.3
-
49
-
-
43049139905
-
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
-
Mullighan CG, Miller CB, Radtke I, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 2008;453:110-114.
-
(2008)
Nature
, vol.453
, pp. 110-114
-
-
Mullighan, C.G.1
Miller, C.B.2
Radtke, I.3
-
50
-
-
84875673056
-
Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia
-
Caye A, Beldjord K, Mass-Malo K, et al. Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia. Haematologica 2013;98:597-601.
-
(2013)
Haematologica
, vol.98
, pp. 597-601
-
-
Caye, A.1
Beldjord, K.2
Mass-Malo, K.3
-
51
-
-
84873571191
-
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations
-
Dupuis A, Gaub MP, Legrain M, et al. Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations. Leukemia 2013;27:503-507.
-
(2013)
Leukemia
, vol.27
, pp. 503-507
-
-
Dupuis, A.1
Gaub, M.P.2
Legrain, M.3
-
52
-
-
84863785952
-
Newly diagnosed acute lymphoblastic leukemia in China (II): Prognosis related to genetic abnormalities in a series of 1091 cases
-
Mi JQ, Wang X, Yao Y, et al. Newly diagnosed acute lymphoblastic leukemia in China (II): prognosis related to genetic abnormalities in a series of 1091 cases. Leukemia 2012;26:1507-1516.
-
(2012)
Leukemia
, vol.26
, pp. 1507-1516
-
-
Mi, J.Q.1
Wang, X.2
Yao, Y.3
-
53
-
-
70449719091
-
IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report
-
Martinelli G, Iacobucci I, Storlazzi CT, et al. IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report. J Clin Oncol 2009;27:5202-5207.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5202-5207
-
-
Martinelli, G.1
Iacobucci, I.2
Storlazzi, C.T.3
-
54
-
-
70349242044
-
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: On behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP)
-
Iacobucci I, Storlazzi CT, Cilloni D, et al. Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP). Blood 2009;114:2159-2167.
-
(2009)
Blood
, vol.114
, pp. 2159-2167
-
-
Iacobucci, I.1
Storlazzi, C.T.2
Cilloni, D.3
-
55
-
-
84888253484
-
Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL
-
van der Veer A, Waanders E, Pieters R, et al. Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL. Blood 2013;122:2622-2629.
-
(2013)
Blood
, vol.122
, pp. 2622-2629
-
-
Van Der Veer, A.1
Waanders, E.2
Pieters, R.3
-
56
-
-
33846869976
-
Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); An MRC UKALL12/ECOG 2993 study
-
Fielding AK, Richards SM, Chopra R, et al. Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study. Blood 2007;109:944-950.
-
(2007)
Blood
, vol.109
, pp. 944-950
-
-
Fielding, A.K.1
Richards, S.M.2
Chopra, R.3
-
57
-
-
77950664722
-
Outcome after relapse of acute lymphoblastic leukemia in adult patients included in four consecutive risk-adapted trials by the PETHEMA Study Group
-
Oriol A, Vives S, Hernandez-Rivas JM, et al. Outcome after relapse of acute lymphoblastic leukemia in adult patients included in four consecutive risk-adapted trials by the PETHEMA Study Group. Haematologica 2010;95:589-596.
-
(2010)
Haematologica
, vol.95
, pp. 589-596
-
-
Oriol, A.1
Vives, S.2
Hernandez-Rivas, J.M.3
-
58
-
-
34548136113
-
Outcome of treatment after first relapse in adults with acute lymphoblastic leukemia initially treated by the LALA-94 trial
-
Tavernier E, Boiron JM, Huguet F, et al. Outcome of treatment after first relapse in adults with acute lymphoblastic leukemia initially treated by the LALA-94 trial. Leukemia 2007;21:1907-1914.
-
(2007)
Leukemia
, vol.21
, pp. 1907-1914
-
-
Tavernier, E.1
Boiron, J.M.2
Huguet, F.3
-
59
-
-
0033214233
-
Primary refractory and relapsed adult acute lymphoblastic leukemia: Characteristics, treatment results, and prognosis with salvage therapy
-
Thomas DA, Kantarjian H, Smith TL, et al. Primary refractory and relapsed adult acute lymphoblastic leukemia: characteristics, treatment results, and prognosis with salvage therapy. Cancer 1999;86:1216-1230.
-
(1999)
Cancer
, vol.86
, pp. 1216-1230
-
-
Thomas, D.A.1
Kantarjian, H.2
Smith, T.L.3
-
60
-
-
0036566540
-
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance
-
Branford S, Rudzki Z, Walsh S, et al. High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance. Blood 2002;99:3472-3475.
-
(2002)
Blood
, vol.99
, pp. 3472-3475
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
-
61
-
-
0036493544
-
Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation
-
Hofmann WK, Jones LC, Lemp NA, et al. Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation. Blood 2002;99:1860-1862.
-
(2002)
Blood
, vol.99
, pp. 1860-1862
-
-
Hofmann, W.K.1
Jones, L.C.2
Lemp, N.A.3
-
62
-
-
2442465000
-
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia
-
Hu Y, Liu Y, Pelletier S, et al. Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 2004;36:453-461.
-
(2004)
Nat Genet
, vol.36
, pp. 453-461
-
-
Hu, Y.1
Liu, Y.2
Pelletier, S.3
-
63
-
-
52049087410
-
Kinase domain point mutations in Philadelphia chromosome-positive acute lymphoblastic leukemia emerge after therapy with BCR-ABL kinase inhibitors
-
Jones D, Thomas D, Yin CC, et al. Kinase domain point mutations in Philadelphia chromosome-positive acute lymphoblastic leukemia emerge after therapy with BCR-ABL kinase inhibitors. Cancer 2008;113:985-994.
-
(2008)
Cancer
, vol.113
, pp. 985-994
-
-
Jones, D.1
Thomas, D.2
Yin, C.C.3
-
64
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah NP, Tran C, Lee FY, et al. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 2004;305:399-401.
-
(2004)
Science
, vol.305
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
-
65
-
-
33846228789
-
Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: By the GIMEMA Working Party on Chronic Myeloid Leukemia
-
Soverini S, Colarossi S, Gnani A, et al. Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia. Clin Cancer Res 2006;12:7374-7379.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7374-7379
-
-
Soverini, S.1
Colarossi, S.2
Gnani, A.3
-
66
-
-
0038156170
-
Presence of the BCR-ABL mutation Glu255Lys prior to STI571 (imatinib) treatment in patients with Ph+ acute lymphoblastic leukemia
-
Hofmann WK, Komor M, Wassmann B, et al. Presence of the BCR-ABL mutation Glu255Lys prior to STI571 (imatinib) treatment in patients with Ph+ acute lymphoblastic leukemia. Blood 2003;102:659-661.
-
(2003)
Blood
, vol.102
, pp. 659-661
-
-
Hofmann, W.K.1
Komor, M.2
Wassmann, B.3
-
67
-
-
34547221085
-
Kinase domain mutations of BCR-ABL frequently precede imatinib-based therapy and give rise to relapse in patients with de novo Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL)
-
Pfeifer H, Wassmann B, Pavlova A, et al. Kinase domain mutations of BCR-ABL frequently precede imatinib-based therapy and give rise to relapse in patients with de novo Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Blood 2007;110:727-734.
-
(2007)
Blood
, vol.110
, pp. 727-734
-
-
Pfeifer, H.1
Wassmann, B.2
Pavlova, A.3
-
68
-
-
21144451094
-
In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
-
O'Hare T, Walters DK, Stoffregen EP, et al. In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res 2005;65:4500-4505.
-
(2005)
Cancer Res
, vol.65
, pp. 4500-4505
-
-
O'Hare, T.1
Walters, D.K.2
Stoffregen, E.P.3
-
69
-
-
58549088155
-
Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants
-
Redaelli S, Piazza R, Rostagno R, et al. Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants. J Clin Oncol 2009;27:469-471.
-
(2009)
J Clin Oncol
, vol.27
, pp. 469-471
-
-
Redaelli, S.1
Piazza, R.2
Rostagno, R.3
-
70
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006;354:2531-2541.
-
(2006)
N Engl J Med
, vol.354
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
-
71
-
-
24644464172
-
AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells
-
Verstovsek S, Golemovic M, Kantarjian H, et al. AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells. Cancer 2005;104:1230-1236.
-
(2005)
Cancer
, vol.104
, pp. 1230-1236
-
-
Verstovsek, S.1
Golemovic, M.2
Kantarjian, H.3
-
72
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
-
Kantarjian H, Giles F, Wunderle L, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med 2006;354:2542-2551.
-
(2006)
N Engl J Med
, vol.354
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderle, L.3
-
73
-
-
77249091826
-
Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study
-
Lilly MB, Ottmann OG, Shah NP, et al. Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study. Am J Hematol 2010;85:164-170.
-
(2010)
Am J Hematol
, vol.85
, pp. 164-170
-
-
Lilly, M.B.1
Ottmann, O.G.2
Shah, N.P.3
-
74
-
-
34948829146
-
Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: Interim results of a phase 2 study
-
Ottmann O, Dombret H, Martinelli G, et al. Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study. Blood 2007;110:2309-2315.
-
(2007)
Blood
, vol.110
, pp. 2309-2315
-
-
Ottmann, O.1
Dombret, H.2
Martinelli, G.3
-
75
-
-
84878907482
-
Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Ottmann OG, Larson RA, Kantarjian HM, et al. Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Leukemia 2013;27:1411-1413.
-
(2013)
Leukemia
, vol.27
, pp. 1411-1413
-
-
Ottmann, O.G.1
Larson, R.A.2
Kantarjian, H.M.3
-
76
-
-
84896811150
-
Phase II trial of hyper CVAD and dasatinib in patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia or blast phase chronic myeloid leukemia
-
Benjamini O, Dumlao TL, Kantarjian H, et al. Phase II trial of hyper CVAD and dasatinib in patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia or blast phase chronic myeloid leukemia. Am J Hematol 2014;89:282-287.
-
(2014)
Am J Hematol
, vol.89
, pp. 282-287
-
-
Benjamini, O.1
Dumlao, T.L.2
Kantarjian, H.3
-
77
-
-
73949105873
-
Dasatinib treatment of chronic-phase chronic myeloid leukemia: Analysis of responses according to preexisting BCR-ABL mutations
-
Muller MC, Cortes JE, Kim DW, et al. Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. Blood 2009;114:4944-4953.
-
(2009)
Blood
, vol.114
, pp. 4944-4953
-
-
Muller, M.C.1
Cortes, J.E.2
Kim, D.W.3
-
78
-
-
34247644944
-
Resistance to dasatinib in Philadelphia-positive leukemia patients and the presence or the selection of mutations at residues 315 and 317 in the BCR-ABL kinase domain
-
Soverini S, Colarossi S, Gnani A, et al. Resistance to dasatinib in Philadelphia-positive leukemia patients and the presence or the selection of mutations at residues 315 and 317 in the BCR-ABL kinase domain. Haematologica 2007;92:401-404.
-
(2007)
Haematologica
, vol.92
, pp. 401-404
-
-
Soverini, S.1
Colarossi, S.2
Gnani, A.3
-
79
-
-
34548825177
-
Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia
-
Soverini S, Martinelli G, Colarossi S, et al. Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia. J Clin Oncol 2006;24:e51-52.
-
(2006)
J Clin Oncol
, vol.24
, pp. e51-52
-
-
Soverini, S.1
Martinelli, G.2
Colarossi, S.3
-
80
-
-
80051573352
-
BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: Recommendations from an expert panel on behalf of European LeukemiaNet
-
Soverini S, Hochhaus A, Nicolini FE, et al. BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet. Blood 2011;118:1208-1215.
-
(2011)
Blood
, vol.118
, pp. 1208-1215
-
-
Soverini, S.1
Hochhaus, A.2
Nicolini, F.E.3
-
81
-
-
85081876900
-
-
U.S. Food and Drug Administration, Accessed August 6, 2015
-
U.S. Food and Drug Administration. Prescribing Information: ICLUSIG® (ponatinib) tablets for oral use. 2012. Available at: http://www.accessdata.fda.gov/drugsatfda-docs/label/2012/203469lbl.pdf. Accessed August 6, 2015
-
(2012)
Prescribing Information: ICLUSIG® (Ponatinib) Tablets for Oral Use
-
-
-
82
-
-
84870012939
-
Ponatinib in refractory Philadelphia chromosome-positive leukemias
-
Cortes JE, Kantarjian H, Shah NP, et al. Ponatinib in refractory Philadelphia chromosome-positive leukemias. N Engl J Med 2012;367:2075-2088.
-
(2012)
N Engl J Med
, vol.367
, pp. 2075-2088
-
-
Cortes, J.E.1
Kantarjian, H.2
Shah, N.P.3
-
83
-
-
84887127701
-
A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias
-
Cortes JE, Kim DW, Pinilla-Ibarz J, et al. A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias. N Engl J Med 2013;369:1783-1796.
-
(2013)
N Engl J Med
, vol.369
, pp. 1783-1796
-
-
Cortes, J.E.1
Kim, D.W.2
Pinilla-Ibarz, J.3
-
84
-
-
80055070888
-
Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib
-
Cortes JE, Kantarjian HM, Brummendorf TH, et al. Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib. Blood 2011;118:4567-4576.
-
(2011)
Blood
, vol.118
, pp. 4567-4576
-
-
Cortes, J.E.1
Kantarjian, H.M.2
Brummendorf, T.H.3
-
85
-
-
84859836481
-
Bosutinib is active in chronic phase chronic myeloid leukemia after imatinib and dasatinib and/or nilotinib therapy failure
-
Khoury HJ, Cortes JE, Kantarjian HM, et al. Bosutinib is active in chronic phase chronic myeloid leukemia after imatinib and dasatinib and/or nilotinib therapy failure. Blood 2012;119:3403-3412.
-
(2012)
Blood
, vol.119
, pp. 3403-3412
-
-
Khoury, H.J.1
Cortes, J.E.2
Kantarjian, H.M.3
-
86
-
-
78549294155
-
Dasatinib followed by second allogeneic hematopoietic stem cell transplantation for relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia after the first transplantation
-
Ishida Y, Terasako K, Oshima K, et al. Dasatinib followed by second allogeneic hematopoietic stem cell transplantation for relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia after the first transplantation. Int J Hematol 2010;92:542-546.
-
(2010)
Int J Hematol
, vol.92
, pp. 542-546
-
-
Ishida, Y.1
Terasako, K.2
Oshima, K.3
-
87
-
-
67650478307
-
Successful second allogeneic stem cell transplantation in second remission induced by dasatinib in a child with Philadelphia chromosome positive acute lymphoblastic leukemia
-
Millot F, Cividin M, Brizard F, et al. Successful second allogeneic stem cell transplantation in second remission induced by dasatinib in a child with Philadelphia chromosome positive acute lymphoblastic leukemia. Pediatr Blood Cancer 2009;52:891-892.
-
(2009)
Pediatr Blood Cancer
, vol.52
, pp. 891-892
-
-
Millot, F.1
Cividin, M.2
Brizard, F.3
-
88
-
-
0033832579
-
Donor leukocyte infusions in acute lymphocytic leukemia
-
Collins RH, Jr., Goldstein S, Giralt S, et al. Donor leukocyte infusions in acute lymphocytic leukemia. Bone Marrow Transplant 2000;26:511-516.
-
(2000)
Bone Marrow Transplant
, vol.26
, pp. 511-516
-
-
Collins, R.H.1
Goldstein, S.2
Giralt, S.3
-
89
-
-
0029100438
-
Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients
-
Kolb HJ, Schattenberg A, Goldman JM, et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood 1995;86:2041-2050.
-
(1995)
Blood
, vol.86
, pp. 2041-2050
-
-
Kolb, H.J.1
Schattenberg, A.2
Goldman, J.M.3
-
90
-
-
0030887758
-
Relapse of Philadelphia chromosome positive acute lymphoblastic leukaemia after marrow transplantation: Sustained molecular remission after early and dose-escalating infusion of donor leucocytes
-
Keil F, Kalhs P, Haas OA, et al. Relapse of Philadelphia chromosome positive acute lymphoblastic leukaemia after marrow transplantation: sustained molecular remission after early and dose-escalating infusion of donor leucocytes. Br J Haematol 1997;97:161-164.
-
(1997)
Br J Haematol
, vol.97
, pp. 161-164
-
-
Keil, F.1
Kalhs, P.2
Haas, O.A.3
-
91
-
-
85047698528
-
Eradication of residual bcr-abl-positive clones by inducing graft-versus-host disease after allogeneic stem cell transplantation in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Matsue K, Tabayashi T, Yamada K, Takeuchi M. Eradication of residual bcr-abl-positive clones by inducing graft-versus-host disease after allogeneic stem cell transplantation in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Bone Marrow Transplant 2002;29:63-66.
-
(2002)
Bone Marrow Transplant
, vol.29
, pp. 63-66
-
-
Matsue, K.1
Tabayashi, T.2
Yamada, K.3
Takeuchi, M.4
-
92
-
-
0031059857
-
Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion
-
Yazaki M, Andoh M, Ito T, et al. Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion. Bone Marrow Transplant 1997;19:393-394.
-
(1997)
Bone Marrow Transplant
, vol.19
, pp. 393-394
-
-
Yazaki, M.1
Andoh, M.2
Ito, T.3
-
93
-
-
55049088837
-
Nilotinib and donor lymphocyte infusion in the treatment of Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) relapsing after allogeneic stem cell transplantation and resistant to imatinib
-
Tiribelli M, Sperotto A, Candoni A, et al. Nilotinib and donor lymphocyte infusion in the treatment of Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) relapsing after allogeneic stem cell transplantation and resistant to imatinib. Leuk Res 2009;33:174-177.
-
(2009)
Leuk Res
, vol.33
, pp. 174-177
-
-
Tiribelli, M.1
Sperotto, A.2
Candoni, A.3
-
94
-
-
60049101574
-
Case of a patient with Philadelphia-chromosome-positive acute lymphoblastic leukemia relapsed after myeloablative allogeneic hematopoietic stem cell transplantation treated successfully with imatinib and sequential donor lymphocyte infusions
-
Yoshimitsu M, Fujiwara H, Ozaki A, et al. Case of a patient with Philadelphia-chromosome-positive acute lymphoblastic leukemia relapsed after myeloablative allogeneic hematopoietic stem cell transplantation treated successfully with imatinib and sequential donor lymphocyte infusions. Int J Hematol 2008;88:331-335.
-
(2008)
Int J Hematol
, vol.88
, pp. 331-335
-
-
Yoshimitsu, M.1
Fujiwara, H.2
Ozaki, A.3
-
95
-
-
79959581259
-
Successful treatment with dasatinib and allogeneic peripheral blood stem cell transplant for imatinib- resistant Philadelphia chromosome-positive acute lymphoblastic leukemia relapsing after bone marrow transplant and donor lymphocyte infusion
-
Tachibana T, Numata A, Tanaka M, et al. Successful treatment with dasatinib and allogeneic peripheral blood stem cell transplant for imatinib- resistant Philadelphia chromosome-positive acute lymphoblastic leukemia relapsing after bone marrow transplant and donor lymphocyte infusion. Leuk Lymphoma 2011;52:1376-1379.
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 1376-1379
-
-
Tachibana, T.1
Numata, A.2
Tanaka, M.3
-
96
-
-
84896335556
-
Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
-
Davila ML, Riviere I, Wang X, et al. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci Transl Med 2014;6:224ra225.
-
(2014)
Sci Transl Med
, vol.6
, pp. 224ra225
-
-
Davila, M.L.1
Riviere, I.2
Wang, X.3
-
97
-
-
57849138262
-
Factors influencing survival after relapse from acute lymphoblastic leukemia: A Children's Oncology Group study
-
Nguyen K, Devidas M, Cheng SC, et al. Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study. Leukemia 2008;22:2142-2150.
-
(2008)
Leukemia
, vol.22
, pp. 2142-2150
-
-
Nguyen, K.1
Devidas, M.2
Cheng, S.C.3
-
98
-
-
0032572912
-
Acute lymphoblastic leukemia
-
Pui CH, Evans WE. Acute lymphoblastic leukemia. N Engl J Med 1998;339:605-615.
-
(1998)
N Engl J Med
, vol.339
, pp. 605-615
-
-
Pui, C.H.1
Evans, W.E.2
-
99
-
-
76749138468
-
Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia
-
Pui CH, Pei D, Sandlund JT, et al. Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia. Leukemia 2010;24:371-382.
-
(2010)
Leukemia
, vol.24
, pp. 371-382
-
-
Pui, C.H.1
Pei, D.2
Sandlund, J.T.3
-
100
-
-
20644464975
-
Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: A report from the Children's Oncology Group
-
Berg SL, Blaney SM, Devidas M, et al. Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group. J Clin Oncol 2005;23:3376-3382.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3376-3382
-
-
Berg, S.L.1
Blaney, S.M.2
Devidas, M.3
-
101
-
-
32944461889
-
Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: Results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Munster Group 87
-
Einsiedel HG, von Stackelberg A, Hartmann R, et al. Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Munster Group 87. J Clin Oncol 2005;23:7942-7950.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7942-7950
-
-
Einsiedel, H.G.1
Von Stackelberg, A.2
Hartmann, R.3
-
102
-
-
77952483774
-
Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: Results of trial ALL-REZ BFM 90
-
Tallen G, Ratei R, Mann G, et al. Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: results of trial ALL-REZ BFM 90. J Clin Oncol 2010;28:2339-2347.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2339-2347
-
-
Tallen, G.1
Ratei, R.2
Mann, G.3
-
103
-
-
37648999300
-
Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952
-
Malempati S, Gaynon PS, Sather H, et al. Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952. J Clin Oncol 2007;25:5800-5807.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5800-5807
-
-
Malempati, S.1
Gaynon, P.S.2
Sather, H.3
-
104
-
-
66549084080
-
Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: Results from the International ALL Trial MRC UKALLXII/ECOG2993
-
Fielding AK, Rowe JM, Richards SM, et al. Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG2993. Blood 2009;113:4489-4496.
-
(2009)
Blood
, vol.113
, pp. 4489-4496
-
-
Fielding, A.K.1
Rowe, J.M.2
Richards, S.M.3
-
105
-
-
85081878079
-
-
Genzyme Corporation Prescribing Information, Accessed August 6, 2015
-
Genzyme Corporation Prescribing Information. Clolar® (clofarabine) Injection for Intravenous Use. 2013. Available at: http://products.sanofi.us/clolar/clolar.html. Accessed August 6, 2015.
-
(2013)
Clolar® (Clofarabine) Injection for Intravenous Use
-
-
-
106
-
-
33646337195
-
Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia
-
Jeha S, Gaynon PS, Razzouk BI, et al. Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia. J Clin Oncol 2006;24:1917-1923.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1917-1923
-
-
Jeha, S.1
Gaynon, P.S.2
Razzouk, B.I.3
-
107
-
-
0141482004
-
Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia
-
Kantarjian H, Gandhi V, Cortes J, et al. Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia. Blood 2003;102:2379-2386.
-
(2003)
Blood
, vol.102
, pp. 2379-2386
-
-
Kantarjian, H.1
Gandhi, V.2
Cortes, J.3
-
108
-
-
70349904430
-
Clofarabine, cyclophosphamide and etoposide as single-course re-induction therapy for children with refractory/multiple relapsed acute lymphoblastic leukaemia
-
Locatelli F, Testi AM, Bernardo ME, et al. Clofarabine, cyclophosphamide and etoposide as single-course re-induction therapy for children with refractory/multiple relapsed acute lymphoblastic leukaemia. Br J Haematol 2009;147:371-378.
-
(2009)
Br J Haematol
, vol.147
, pp. 371-378
-
-
Locatelli, F.1
Testi, A.M.2
Bernardo, M.E.3
-
109
-
-
82955207681
-
Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia
-
Hijiya N, Thomson B, Isakoff MS, et al. Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia. Blood 2011;118:6043-6049.
-
(2011)
Blood
, vol.118
, pp. 6043-6049
-
-
Hijiya, N.1
Thomson, B.2
Isakoff, M.S.3
-
110
-
-
84861721732
-
Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients
-
Miano M, Pistorio A, Putti MC, et al. Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients. Leuk Lymphoma 2012;53:1693-1698.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 1693-1698
-
-
Miano, M.1
Pistorio, A.2
Putti, M.C.3
-
111
-
-
79960844332
-
Early UK experience in the use of clofarabine in the treatment of relapsed and refractory paediatric acute lymphoblastic leukaemia
-
O'Connor D, Sibson K, Caswell M, et al. Early UK experience in the use of clofarabine in the treatment of relapsed and refractory paediatric acute lymphoblastic leukaemia. Br J Haematol 2011;154:482-485.
-
(2011)
Br J Haematol
, vol.154
, pp. 482-485
-
-
O'Connor, D.1
Sibson, K.2
Caswell, M.3
-
112
-
-
84874614726
-
Clofarabine Combinations in Adults with Refractory/Relapsed Acute Lymphoblastic Leukemia (ALL): A GRAALL Report [abstract]
-
Abstract 2586
-
Pigneux A, Sauvezie M, Vey N, et al. Clofarabine Combinations in Adults with Refractory/Relapsed Acute Lymphoblastic Leukemia (ALL): A GRAALL Report [abstract]. Blood 2011;118:Abstract 2586.
-
(2011)
Blood
, vol.118
-
-
Pigneux, A.1
Sauvezie, M.2
Vey, N.3
-
113
-
-
0027322252
-
Phase II study of etoposide, ifosfamide, and mitoxantrone for the treatment of resistant adult acute lymphoblastic leukemia
-
Schiller G, Lee M, Territo M, et al. Phase II study of etoposide, ifosfamide, and mitoxantrone for the treatment of resistant adult acute lymphoblastic leukemia. Am J Hematol 1993;43:195-199.
-
(1993)
Am J Hematol
, vol.43
, pp. 195-199
-
-
Schiller, G.1
Lee, M.2
Territo, M.3
-
114
-
-
0036682235
-
A single, high dose of idarubicin combined with cytarabine as induction therapy for adult patients with recurrent or refractory acute lymphoblastic leukemia
-
Weiss MA, Aliff TB, Tallman MS, et al. A single, high dose of idarubicin combined with cytarabine as induction therapy for adult patients with recurrent or refractory acute lymphoblastic leukemia. Cancer 2002;95:581-587.
-
(2002)
Cancer
, vol.95
, pp. 581-587
-
-
Weiss, M.A.1
Aliff, T.B.2
Tallman, M.S.3
-
115
-
-
79953727884
-
Augmented hyper-CVAD based on dose-intensified vincristine, dexamethasone, and asparaginase in adult acute lymphoblastic leukemia salvage therapy
-
Faderl S, Thomas DA, O'Brien S, et al. Augmented hyper-CVAD based on dose-intensified vincristine, dexamethasone, and asparaginase in adult acute lymphoblastic leukemia salvage therapy. Clin Lymphoma Myeloma Leuk 2011;11:54-59.
-
(2011)
Clin Lymphoma Myeloma Leuk
, vol.11
, pp. 54-59
-
-
Faderl, S.1
Thomas, D.A.2
O'Brien, S.3
-
116
-
-
85081878240
-
-
GlaxoSmithKline, Accessed August 6, 2015
-
GlaxoSmithKline. Prescribing Information. ARRANON (nelarabine) Injection. 2011. Available at: http://us.gsk.com/products/assets/us-arranon.pdf. Accessed August 6, 2015.
-
(2011)
Prescribing Information. ARRANON (Nelarabine) Injection
-
-
-
117
-
-
34250003760
-
Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801
-
DeAngelo DJ, Yu D, Johnson JL, et al. Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801. Blood 2007;109:5136-5142.
-
(2007)
Blood
, vol.109
, pp. 5136-5142
-
-
DeAngelo, D.J.1
Yu, D.2
Johnson, J.L.3
-
118
-
-
72249112336
-
Phase 1 multicenter study of vincristine sulfate liposomes injection and dexamethasone in adults with relapsed or refractory acute lymphoblastic leukemia
-
Thomas DA, Kantarjian HM, Stock W, et al. Phase 1 multicenter study of vincristine sulfate liposomes injection and dexamethasone in adults with relapsed or refractory acute lymphoblastic leukemia. Cancer 2009;115:5490-5498.
-
(2009)
Cancer
, vol.115
, pp. 5490-5498
-
-
Thomas, D.A.1
Kantarjian, H.M.2
Stock, W.3
-
119
-
-
84892924472
-
Pharmacokinetics and pharmacodynamics of vincristine sulfate liposome injection (VSLI) in adults with acute lymphoblastic leukemia
-
Silverman JA, Reynolds L, Deitcher SR. Pharmacokinetics and pharmacodynamics of vincristine sulfate liposome injection (VSLI) in adults with acute lymphoblastic leukemia. J Clin Pharmacol 2013;53:1139-1145.
-
(2013)
J Clin Pharmacol
, vol.53
, pp. 1139-1145
-
-
Silverman, J.A.1
Reynolds, L.2
Deitcher, S.R.3
-
120
-
-
84875716409
-
High-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia
-
O'Brien S, Schiller G, Lister J, et al. High-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia. J Clin Oncol 2013;31:676-683.
-
(2013)
J Clin Oncol
, vol.31
, pp. 676-683
-
-
O'Brien, S.1
Schiller, G.2
Lister, J.3
-
121
-
-
58149394138
-
Outcome of adults with acute lymphocytic leukemia after second salvage therapy
-
O'Brien S, Thomas D, Ravandi F, et al. Outcome of adults with acute lymphocytic leukemia after second salvage therapy. Cancer 2008;113:3186-3191.
-
(2008)
Cancer
, vol.113
, pp. 3186-3191
-
-
O'Brien, S.1
Thomas, D.2
Ravandi, F.3
-
123
-
-
84856994479
-
Anti-CD19 BiTE blinatumomab induces high complete remission rate in adult patients with relapsed B-precursor ALL: Updated results of an ongoing phase II trial [abstract]
-
Abstract 252
-
Topp MS, Goekbuget N, Zugmaier G, et al. Anti-CD19 BiTE blinatumomab induces high complete remission rate in adult patients with relapsed B-precursor ALL: updated results of an ongoing phase II trial [abstract]. Blood 2011;118:Abstract 252.
-
(2011)
Blood
, vol.118
-
-
Topp, M.S.1
Goekbuget, N.2
Zugmaier, G.3
-
124
-
-
79959312575
-
Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival
-
Topp MS, Kufer P, Gokbuget N, et al. Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J Clin Oncol 2011;29:2493-2498.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2493-2498
-
-
Topp, M.S.1
Kufer, P.2
Gokbuget, N.3
-
125
-
-
84923106056
-
Confirmatory open-label, single-arm, multicenter phase 2 study of the BiTE antibody blinatumomab in patients (pts) with relapsed/refractory B-precursor acute lymphoblastic leukemia (r/r ALL) [abstract]
-
Abstract 7005
-
Topp MS, Goekbuget N, Stein AS, et al. Confirmatory open-label, single-arm, multicenter phase 2 study of the BiTE antibody blinatumomab in patients (pts) with relapsed/refractory B-precursor acute lymphoblastic leukemia (r/r ALL) [abstract]. J Clin Oncol 2014;32:Abstract 7005.
-
(2014)
J Clin Oncol
, vol.32
-
-
Topp, M.S.1
Goekbuget, N.2
Stein, A.S.3
-
126
-
-
85045483727
-
-
U.S. Food and Drug Administration, Accessed August 6, 2015
-
U.S. Food and Drug Administration. Prescribing Information. Blincyto® (blinatumomab) injection. 2014. Available at: http://www.accessdata.fda.gov/drugsatfda-docs/label/2014/125557lbl.pdf. Accessed August 6, 2015.
-
(2014)
Prescribing Information. Blincyto® (Blinatumomab) Injection
-
-
-
127
-
-
84876005284
-
CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
-
Brentjens RJ, Davila ML, Riviere I, et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 2013;5:177ra138.
-
(2013)
Sci Transl Med
, vol.5
, pp. 177ra138
-
-
Brentjens, R.J.1
Davila, M.L.2
Riviere, I.3
-
128
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
Kochenderfer JN, Dudley ME, Feldman SA, et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 2012;119:2709-2720.
-
(2012)
Blood
, vol.119
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
-
129
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp SA, Kalos M, Barrett D, et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med 2013;368:1509-1518.
-
(2013)
N Engl J Med
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
-
130
-
-
0037264471
-
Targeting tumours with genetically enhanced T lymphocytes
-
Sadelain M, Riviere I, Brentjens R. Targeting tumours with genetically enhanced T lymphocytes. Nat Rev Cancer 2003;3:35-45.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 35-45
-
-
Sadelain, M.1
Riviere, I.2
Brentjens, R.3
-
131
-
-
63649112916
-
Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy
-
Hollyman D, Stefanski J, Przybylowski M, et al. Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy. J Immunother 2009;32:169-180.
-
(2009)
J Immunother
, vol.32
, pp. 169-180
-
-
Hollyman, D.1
Stefanski, J.2
Przybylowski, M.3
-
132
-
-
84866094086
-
Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation
-
Gokbuget N, Stanze D, Beck J, et al. Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation. Blood 2012;120:2032-2041.
-
(2012)
Blood
, vol.120
, pp. 2032-2041
-
-
Gokbuget, N.1
Stanze, D.2
Beck, J.3
-
133
-
-
85081877882
-
CD19-Targeted 19-28z CAR modified autologous T cells induce high rates of complete remission and durable responses in adult patients with relapsed, refractory B-cell ALL [abstract]
-
Presented at, December 06-09, San Francisco, CA. Abstract
-
Park JH, Riviere I, Wang X, et al. CD19-Targeted 19-28z CAR modified autologous T cells induce high rates of complete remission and durable responses in adult patients with relapsed, refractory B-cell ALL [abstract]. Presented at the 56th Annual Meeting of the American-Society-of-Hematology; December 06-09, 2014; San Francisco, CA. Abstract: 382.
-
(2014)
The 56th Annual Meeting of the American-Society-of-Hematology;
, pp. 382
-
-
Park, J.H.1
Riviere, I.2
Wang, X.3
-
134
-
-
84897548232
-
T cells engineered with a chimeric antigen receptor (CAR) targeting CD19 (CTL019) produce significant in vivo proliferation, complete responses and long-term persistence without GVHD in children and adults with relapsed, refractory ALL [abstract]
-
Abstract 67
-
Grupp SA, Frey NV, Aplenc R, et al. T cells engineered with a chimeric antigen receptor (CAR) targeting CD19 (CTL019) produce significant in vivo proliferation, complete responses and long-term persistence without GVHD in children and adults with relapsed, refractory ALL [abstract]. Blood 2013;122:Abstract 67.
-
(2013)
Blood
, vol.122
-
-
Grupp, S.A.1
Frey, N.V.2
Aplenc, R.3
-
135
-
-
84908073316
-
Chimeric antigen receptor T cells for sustained remissions in leukemia
-
Maude SL, Frey N, Shaw PA, et al. Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med 2014;371:1507-1517.
-
(2014)
N Engl J Med
, vol.371
, pp. 1507-1517
-
-
Maude, S.L.1
Frey, N.2
Shaw, P.A.3
-
136
-
-
84862786326
-
Inotuzumab ozogamicin, an anti-CD22-calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: A phase 2 study
-
Kantarjian H, Thomas D, Jorgensen J, et al. Inotuzumab ozogamicin, an anti-CD22-calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: a phase 2 study. Lancet Oncol 2012;13:403-411.
-
(2012)
Lancet Oncol
, vol.13
, pp. 403-411
-
-
Kantarjian, H.1
Thomas, D.2
Jorgensen, J.3
-
137
-
-
85081882279
-
Efficacy and safety of inotuzumab ozogamicin (INO) vs standard of care (SOC) in salvage 1 or 2 patients with acute lymphoblastic leukemia (ALL): An ongoing global phase 3 study [abstract]
-
Presented at, Vienna Austria:Abstract LB2073
-
DeAngelo DJ, Stelljes M, Martinelli G, et al. Efficacy and safety of inotuzumab ozogamicin (INO) vs standard of care (SOC) in salvage 1 or 2 patients with acute lymphoblastic leukemia (ALL): An ongoing global phase 3 study [abstract]. Presented at: 20th Congress of the European Hematology Association (EHA) 2015;Vienna, Austria:Abstract LB2073.
-
(2015)
20th Congress of the European Hematology Association (EHA)
-
-
DeAngelo, D.J.1
Stelljes, M.2
Martinelli, G.3
-
138
-
-
29844438604
-
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: An evidence-based review
-
Hahn T, Wall D, Camitta B, et al. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review. Biol Blood Marrow Transplant 2006;12:1-30.
-
(2006)
Biol Blood Marrow Transplant
, vol.12
, pp. 1-30
-
-
Hahn, T.1
Wall, D.2
Camitta, B.3
-
139
-
-
33745080964
-
Outcomes after HLA-matched sibling transplantation or chemotherapy in children with B-precursor acute lymphoblastic leukemia in a second remission: A collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research
-
Eapen M, Raetz E, Zhang MJ, et al. Outcomes after HLA-matched sibling transplantation or chemotherapy in children with B-precursor acute lymphoblastic leukemia in a second remission: a collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research. Blood 2006;107:4961-4967.
-
(2006)
Blood
, vol.107
, pp. 4961-4967
-
-
Eapen, M.1
Raetz, E.2
Zhang, M.J.3
-
140
-
-
84872295739
-
Acute Leukemia Stem Cell Transplantation Trialists' Collaborative G. Allogeneic but not autologous, hematopoietic cell transplantation improves survival only among younger adults with acute lymphoblastic leukemia in first remission: An individual patient data meta-analysis
-
Gupta V, Richards S, Rowe J, Acute Leukemia Stem Cell Transplantation Trialists' Collaborative G. Allogeneic, but not autologous, hematopoietic cell transplantation improves survival only among younger adults with acute lymphoblastic leukemia in first remission: an individual patient data meta-analysis. Blood 2013;121:339-350.
-
(2013)
Blood
, vol.121
, pp. 339-350
-
-
Gupta, V.1
Richards, S.2
Rowe, J.3
-
141
-
-
84883134501
-
Acute lymphoblastic leukemia in first complete remission: Temporal trend of outcomes in studies comparing allogeneic transplant with autologous transplant or chemotherapy
-
Messori A, Fadda V, Maratea D, Trippoli S. Acute lymphoblastic leukemia in first complete remission: temporal trend of outcomes in studies comparing allogeneic transplant with autologous transplant or chemotherapy. Ann Hematol 2013;92:1221-1228.
-
(2013)
Ann Hematol
, vol.92
, pp. 1221-1228
-
-
Messori, A.1
Fadda, V.2
Maratea, D.3
Trippoli, S.4
-
142
-
-
0037083570
-
Minimal residual disease tests provide an independent predictor of clinical outcome in adult acute lymphoblastic leukemia
-
Mortuza FY, Papaioannou M, Moreira IM, et al. Minimal residual disease tests provide an independent predictor of clinical outcome in adult acute lymphoblastic leukemia. J Clin Oncol 2002;20:1094-1104.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1094-1104
-
-
Mortuza, F.Y.1
Papaioannou, M.2
Moreira, I.M.3
-
143
-
-
2342540402
-
Comparative analysis of flow cytometry and polymerase chain reaction for the detection of minimal residual disease in childhood acute lymphoblastic leukemia
-
Neale GA, Coustan-Smith E, Stow P, et al. Comparative analysis of flow cytometry and polymerase chain reaction for the detection of minimal residual disease in childhood acute lymphoblastic leukemia. Leukemia 2004;18:934-938.
-
(2004)
Leukemia
, vol.18
, pp. 934-938
-
-
Neale, G.A.1
Coustan-Smith, E.2
Stow, P.3
-
144
-
-
20144386608
-
Concurrent detection of minimal residual disease (MRD) in childhood acute lymphoblastic leukaemia by flow cytometry and real-time PCR
-
Kerst G, Kreyenberg H, Roth C, et al. Concurrent detection of minimal residual disease (MRD) in childhood acute lymphoblastic leukaemia by flow cytometry and real-time PCR. Br J Haematol 2005;128:774-782.
-
(2005)
Br J Haematol
, vol.128
, pp. 774-782
-
-
Kerst, G.1
Kreyenberg, H.2
Roth, C.3
-
145
-
-
0036660158
-
Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia
-
Coustan-Smith E, Sancho J, Behm FG, et al. Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia. Blood 2002;100:52-58.
-
(2002)
Blood
, vol.100
, pp. 52-58
-
-
Coustan-Smith, E.1
Sancho, J.2
Behm, F.G.3
-
146
-
-
0034667685
-
Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia
-
Coustan-Smith E, Sancho J, Hancock ML, et al. Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia. Blood 2000;96:2691-2696.
-
(2000)
Blood
, vol.96
, pp. 2691-2696
-
-
Coustan-Smith, E.1
Sancho, J.2
Hancock, M.L.3
-
147
-
-
0032572924
-
Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European Organization for Research and Treatment of Cancer-Childhood Leukemia Cooperative Group
-
Cave H, van der Werff ten Bosch J, Suciu S, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European Organization for Research and Treatment of Cancer-Childhood Leukemia Cooperative Group. N Engl J Med 1998;339:591-598.
-
(1998)
N Engl J Med
, vol.339
, pp. 591-598
-
-
Cave, H.1
Van Der Werff Ten Bosch, J.2
Suciu, S.3
-
148
-
-
0347184138
-
Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemia
-
Coustan-Smith E, Behm FG, Sanchez J, et al. Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemia. Lancet 1998;351:550-554.
-
(1998)
Lancet
, vol.351
, pp. 550-554
-
-
Coustan-Smith, E.1
Behm, F.G.2
Sanchez, J.3
-
149
-
-
77954727839
-
Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia
-
Stow P, Key L, Chen X, et al. Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia. Blood 2010;115:4657-4663.
-
(2010)
Blood
, vol.115
, pp. 4657-4663
-
-
Stow, P.1
Key, L.2
Chen, X.3
-
150
-
-
77951441599
-
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: Results in 3184 patients of the AIEOP-BFM ALL 2000 study
-
Conter V, Bartram CR, Valsecchi MG, et al. Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study. Blood 2010;115:3206-3214.
-
(2010)
Blood
, vol.115
, pp. 3206-3214
-
-
Conter, V.1
Bartram, C.R.2
Valsecchi, M.G.3
-
151
-
-
84875273960
-
Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): A randomised controlled trial
-
Vora A, Goulden N, Wade R, et al. Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial. Lancet Oncol 2013;14:199-209.
-
(2013)
Lancet Oncol
, vol.14
, pp. 199-209
-
-
Vora, A.1
Goulden, N.2
Wade, R.3
-
152
-
-
84903541143
-
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): A randomised controlled trial
-
Vora A, Goulden N, Mitchell C, et al. Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial. Lancet Oncol 2014;15:809-818.
-
(2014)
Lancet Oncol
, vol.15
, pp. 809-818
-
-
Vora, A.1
Goulden, N.2
Mitchell, C.3
-
153
-
-
84893452297
-
Use of allogeneic hematopoietic stem-cell transplantation based on minimal residual disease response improves outcomes for children with relapsed acute lymphoblastic leukemia in the intermediate-risk group
-
Eckert C, Henze G, Seeger K, et al. Use of allogeneic hematopoietic stem-cell transplantation based on minimal residual disease response improves outcomes for children with relapsed acute lymphoblastic leukemia in the intermediate-risk group. J Clin Oncol 2013;31:2736-2742.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2736-2742
-
-
Eckert, C.1
Henze, G.2
Seeger, K.3
-
154
-
-
78650168918
-
Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): An open-label randomised trial
-
Parker C, Waters R, Leighton C, et al. Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial. Lancet 2010;376:2009-2017.
-
(2010)
Lancet
, vol.376
, pp. 2009-2017
-
-
Parker, C.1
Waters, R.2
Leighton, C.3
-
155
-
-
77449130934
-
Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: A Therapeutic Advances in Childhood Leukemia Consortium study
-
Ko RH, Ji L, Barnette P, et al. Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium study. J Clin Oncol 2010;28:648-654.
-
(2010)
J Clin Oncol
, vol.28
, pp. 648-654
-
-
Ko, R.H.1
Ji, L.2
Barnette, P.3
-
156
-
-
1542503795
-
Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia after first relapse
-
Coustan-Smith E, Gajjar A, Hijiya N, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia after first relapse. Leukemia 2004;18:499-504.
-
(2004)
Leukemia
, vol.18
, pp. 499-504
-
-
Coustan-Smith, E.1
Gajjar, A.2
Hijiya, N.3
-
157
-
-
57849085208
-
Minimal residual disease is an important predictive factor of outcome in children with relapsed 'high-risk' acute lymphoblastic leukemia
-
Paganin M, Zecca M, Fabbri G, et al. Minimal residual disease is an important predictive factor of outcome in children with relapsed 'high-risk' acute lymphoblastic leukemia. Leukemia 2008;22:2193-2200.
-
(2008)
Leukemia
, vol.22
, pp. 2193-2200
-
-
Paganin, M.1
Zecca, M.2
Fabbri, G.3
-
158
-
-
70449711125
-
Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow
-
Basso G, Veltroni M, Valsecchi MG, et al. Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. J Clin Oncol 2009;27:5168-5174.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5168-5174
-
-
Basso, G.1
Veltroni, M.2
Valsecchi, M.G.3
-
159
-
-
0034141517
-
Rapid molecular response during early induction chemotherapy predicts a good outcome in childhood acute lymphoblastic leukemia
-
Panzer-Grumayer ER, Schneider M, Panzer S, et al. Rapid molecular response during early induction chemotherapy predicts a good outcome in childhood acute lymphoblastic leukemia. Blood 2000;95:790-794.
-
(2000)
Blood
, vol.95
, pp. 790-794
-
-
Panzer-Grumayer, E.R.1
Schneider, M.2
Panzer, S.3
-
160
-
-
31544467825
-
Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia
-
Bruggemann M, Raff T, Flohr T, et al. Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia. Blood 2006;107:1116-1123.
-
(2006)
Blood
, vol.107
, pp. 1116-1123
-
-
Bruggemann, M.1
Raff, T.2
Flohr, T.3
-
161
-
-
47349121885
-
Status of minimal residual disease after induction predicts outcome in both standard and high-risk Ph-negative adult acute lymphoblastic leukaemia. The Polish Adult Leukemia Group ALL 4-2002 MRD Study
-
Holowiecki J, Krawczyk-Kulis M, Giebel S, et al. Status of minimal residual disease after induction predicts outcome in both standard and high-risk Ph-negative adult acute lymphoblastic leukaemia. The Polish Adult Leukemia Group ALL 4-2002 MRD Study. Br J Haematol 2008;142:227-237.
-
(2008)
Br J Haematol
, vol.142
, pp. 227-237
-
-
Holowiecki, J.1
Krawczyk-Kulis, M.2
Giebel, S.3
-
162
-
-
72249121442
-
Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: Final results of the international trial UKALL XII/ECOG2993
-
Patel B, Rai L, Buck G, et al. Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993. Br J Haematol 2010;148:80-89.
-
(2010)
Br J Haematol
, vol.148
, pp. 80-89
-
-
Patel, B.1
Rai, L.2
Buck, G.3
-
163
-
-
10744227340
-
Minimal residual disease in adolescent (older than 14 years) and adult acute lymphoblastic leukemias: Early immunophenotypic evaluation has high clinical value
-
Vidriales MB, Perez JJ, Lopez-Berges MC, et al. Minimal residual disease in adolescent (older than 14 years) and adult acute lymphoblastic leukemias: early immunophenotypic evaluation has high clinical value. Blood 2003;101:4695-4700.
-
(2003)
Blood
, vol.101
, pp. 4695-4700
-
-
Vidriales, M.B.1
Perez, J.J.2
Lopez-Berges, M.C.3
-
164
-
-
84873255438
-
Monitoring of minimal residual disease (MRD) is useful to predict prognosis of adult patients with Ph-negative ALL: Results of a prospective study (ALL MRD2002 Study)
-
Nagafuji K, Miyamoto T, Eto T, et al. Monitoring of minimal residual disease (MRD) is useful to predict prognosis of adult patients with Ph-negative ALL: results of a prospective study (ALL MRD2002 Study). J Hematol Oncol 2013;6:14.
-
(2013)
J Hematol Oncol
, vol.6
, pp. 14
-
-
Nagafuji, K.1
Miyamoto, T.2
Eto, T.3
-
165
-
-
66149141393
-
Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)
-
Bassan R, Spinelli O, Oldani E, et al. Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL). Blood 2009;113:4153-4162.
-
(2009)
Blood
, vol.113
, pp. 4153-4162
-
-
Bassan, R.1
Spinelli, O.2
Oldani, E.3
-
166
-
-
33846882622
-
M olecular relapse in adult standard-risk ALL patients detected by prospective MRD monitoring during and after maintenance treatment: Data from the GMALL 06/99 and 07/03 trials
-
Raff T, Gokbuget N, Luschen S, et al. M olecular relapse in adult standard-risk ALL patients detected by prospective MRD monitoring during and after maintenance treatment: data from the GMALL 06/99 and 07/03 trials. Blood 2007;109:910-915.
-
(2007)
Blood
, vol.109
, pp. 910-915
-
-
Raff, T.1
Gokbuget, N.2
Luschen, S.3
-
167
-
-
84865709936
-
Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies
-
Gokbuget N, Kneba M, Raff T, et al. Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies. Blood 2012;120:1868-1876.
-
(2012)
Blood
, vol.120
, pp. 1868-1876
-
-
Gokbuget, N.1
Kneba, M.2
Raff, T.3
-
168
-
-
0037085750
-
Prognostic significance and modalities of flow cytometric minimal residual disease detection in childhood acute lymphoblastic leukemia
-
Dworzak MN, Froschl G, Printz D, et al. Prognostic significance and modalities of flow cytometric minimal residual disease detection in childhood acute lymphoblastic leukemia. Blood 2002;99:1952-1958.
-
(2002)
Blood
, vol.99
, pp. 1952-1958
-
-
Dworzak, M.N.1
Froschl, G.2
Printz, D.3
-
169
-
-
77949424466
-
Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel Germany 18-20 September 2008
-
Bruggemann M, Schrauder A, Raff T, et al. Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008. Leukemia 2010;24:521-535.
-
(2010)
Leukemia
, vol.24
, pp. 521-535
-
-
Bruggemann, M.1
Schrauder, A.2
Raff, T.3
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