Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Volumn 24, Issue 33, 2006, Pages

  Soverini, Simona ^a   Martinelli, Giovanni ^a   Colarossi, Sabrina ^a   Gnani, Alessandra ^a   Castagnetti, Fausto ^a   Rosti, Gianantonio ^a   Bosi, Costanza ^a   Paolini, Stefania ^a   Rondoni, Michela ^a   Piccaluga, Pier Paolo ^a   Palandri, Francesca ^a   Giannoulia, Panagiota ^a   Marzocchi, Giulia ^a   Luatti, Simona ^a   Testoni, Nicoletta ^a   Iacobucci, Ilaria ^a   Cilloni, Daniela ^a   Saglio, Giuseppe ^a   Baccarani, Michele ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DASATINIB; LEUCINE; PHENYLALANINE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; THIAZOLE DERIVATIVE;

ACUTE LYMPHOCYTIC LEUKEMIA; ADULT; BLAST CELL CRISIS; CASE REPORT; DISEASE COURSE; DRUG RESISTANCE; FEMALE; GENETICS; HUMAN; LETTER; MALE; MIDDLE AGED; MUTATION; MYELOID LEUKEMIA; ONCOGENE; PHASE 2 CLINICAL TRIAL; TREATMENT FAILURE;

ADULT; ANTINEOPLASTIC AGENTS; BLAST CRISIS; CLINICAL TRIALS, PHASE II; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; FEMALE; GENES, ABL; HUMANS; LEUCINE; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MALE; MIDDLE AGED; MUTATION; PHENYLALANINE; PROTEIN KINASE INHIBITORS; PYRIMIDINES; THIAZOLES; TREATMENT FAILURE;

EID: 34548825177     PISSN: None     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2006.08.9128     Document Type: Letter

References (0)