Divalent Metal Ions Mg2+ and Ca2+ Have Distinct Effects on Protein Kinase A Activity and Regulation

ACS Chemical Biology

Volumn 10, Issue 10, 2015, Pages 2303-2315

  Knape, Matthias J ^a   Ahuja, Lalima G ^b   Bertinetti, Daniela ^a   Burghardt, Nicole C G ^a   Zimmermann, Bastian ^c   Taylor, Susan S ^b   Herberg, Friedrich W ^a  

^a UNIVERSITY OF KASSEL   (Germany)

^b San Diego   (United States)

^c Biaffin GmbH and CoKG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; MAGNESIUM ION; CALCIUM; DIVALENT CATION; ION; MAGNESIUM;

ARTICLE; BINDING AFFINITY; CALCIUM SIGNALING; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE POLARIZATION; PHOSPHORYLATION; PRIORITY JOURNAL; REGULATORY MECHANISM; STEADY STATE; SURFACE PLASMON RESONANCE; AMINO ACID SEQUENCE; BINDING SITE; BIOLOGICAL MODEL; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; BINDING SITES; CALCIUM; CATIONS, DIVALENT; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IONS; MAGNESIUM; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT;

EID: 84944747886     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b00271     Document Type: Article

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