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Volumn 6, Issue 29, 2015, Pages 27478-27489

Myeloid-derived suppressor cells contribute to A2B adenosine receptor-induced VEGF production and angiogenesis in a mouse melanoma model

Author keywords

A2B adenosine receptor; Melanoma; Myeloid derived suppressor cells; Tumor angiogenesis

Indexed keywords

ADENOSINE A2B RECEPTOR; STAT3 PROTEIN; VASCULOTROPIN A; AMINOPYRIDINE DERIVATIVE; ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; BAY 60-6583; CD11B ANTIGEN; LY ANTIGEN; LY6G ANTIGEN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE;

EID: 84944463131     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4393     Document Type: Article
Times cited : (92)

References (53)
  • 1
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev. 2001; 53:527-552.
    • (2001) Pharmacol Rev. , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.N.4    Linden, J.5
  • 2
    • 0035924320 scopus 로고    scopus 로고
    • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
    • Ohta A, Sitkovsky M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature. 2001; 414:916-920.
    • (2001) Nature. , vol.414 , pp. 916-920
    • Ohta, A.1    Sitkovsky, M.2
  • 3
    • 84888385324 scopus 로고    scopus 로고
    • Immunity, inflammation and cancer: a leading role for adenosine
    • Antonioli L, Blandizzi C, Pacher P, Haskó G. Immunity, inflammation and cancer: a leading role for adenosine. Nat Rev Cancer. 2013; 13:842-857.
    • (2013) Nat Rev Cancer. , vol.13 , pp. 842-857
    • Antonioli, L.1    Blandizzi, C.2    Pacher, P.3    Haskó, G.4
  • 4
    • 0030785819 scopus 로고    scopus 로고
    • The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine
    • Blay J, White TD, Hoskin DW. The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine. Cancer Res. 1997; 57:2602-2605.
    • (1997) Cancer Res. , vol.57 , pp. 2602-2605
    • Blay, J.1    White, T.D.2    Hoskin, D.W.3
  • 5
    • 84902688437 scopus 로고    scopus 로고
    • Immunoregulatory activity of adenosine and its role in human cancer progression
    • Muller-Haegele S, Muller L, Whiteside TL. Immunoregulatory activity of adenosine and its role in human cancer progression. Expert Rev Clin Immunol. 2014; 10:897-914.
    • (2014) Expert Rev Clin Immunol. , vol.10 , pp. 897-914
    • Muller-Haegele, S.1    Muller, L.2    Whiteside, T.L.3
  • 6
    • 84964315622 scopus 로고    scopus 로고
    • Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists
    • Sitkovsky MV, Hatfield S, Abbott R, Belikoff B, Lukashev D, Ohta A. Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists. Cancer Immunol Res. 2014; 2:598-605.
    • (2014) Cancer Immunol Res. , vol.2 , pp. 598-605
    • Sitkovsky, M.V.1    Hatfield, S.2    Abbott, R.3    Belikoff, B.4    Lukashev, D.5    Ohta, A.6
  • 10
    • 0037155773 scopus 로고    scopus 로고
    • Differential expression of adenosine receptors in human endothelial cells: role of A2B receptors in angiogenic factor regulation
    • Feoktistov I, Goldstein AE, Ryzhov S, Zeng D, Belardinelli L, Voyno-Yasenetskaya T, Biaggioni I. Differential expression of adenosine receptors in human endothelial cells: role of A2B receptors in angiogenic factor regulation. Circ Res. 2002; 90:531-538.
    • (2002) Circ Res. , vol.90 , pp. 531-538
    • Feoktistov, I.1    Goldstein, A.E.2    Ryzhov, S.3    Zeng, D.4    Belardinelli, L.5    Voyno-Yasenetskaya, T.6    Biaggioni, I.7
  • 11
    • 7244234161 scopus 로고    scopus 로고
    • Hypoxia modulates adenosine receptors in human endothelial and smooth muscle cells toward an A2B angiogenic phenotype
    • Feoktistov I, Ryzhov S, Zhong H, Goldstein AE, Matafonov A, Zeng D, Biaggioni I. Hypoxia modulates adenosine receptors in human endothelial and smooth muscle cells toward an A2B angiogenic phenotype. Hypertension. 2004; 44:649-654.
    • (2004) Hypertension. , vol.44 , pp. 649-654
    • Feoktistov, I.1    Ryzhov, S.2    Zhong, H.3    Goldstein, A.E.4    Matafonov, A.5    Zeng, D.6    Biaggioni, I.7
  • 12
    • 70249123905 scopus 로고    scopus 로고
    • A(2B) and A(3) adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin
    • Merighi S, Simioni C, Gessi S, Varani K, Mirandola P, Tabrizi MA, Baraldi PG, Borea PA. A(2B) and A(3) adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin. Neoplasia. 2009; 11:1064-1073.
    • (2009) Neoplasia. , vol.11 , pp. 1064-1073
    • Merighi, S.1    Simioni, C.2    Gessi, S.3    Varani, K.4    Mirandola, P.5    Tabrizi, M.A.6    Baraldi, P.G.7    Borea, P.A.8
  • 16
    • 84872559040 scopus 로고    scopus 로고
    • The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells
    • Lindau D, Gielen P, Kroesen M, Wesseling P, Adema GJ. The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells. Immunology. 2013; 138:105-115.
    • (2013) Immunology. , vol.138 , pp. 105-115
    • Lindau, D.1    Gielen, P.2    Kroesen, M.3    Wesseling, P.4    Adema, G.J.5
  • 17
    • 84866916560 scopus 로고    scopus 로고
    • Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives
    • Raber P, Ochoa AC, Rodríguez PC. Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunol Invest. 2012; 41:614-634.
    • (2012) Immunol Invest. , vol.41 , pp. 614-634
    • Raber, P.1    Ochoa, A.C.2    Rodríguez, P.C.3
  • 20
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • Murdoch C, Muthana M, Coffelt SB, Lewis CE. The role of myeloid cells in the promotion of tumour angiogenesis. Nat. Rev. Cancer. 2008; 8:618-631.
    • (2008) Nat. Rev. Cancer. , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 21
    • 0032400862 scopus 로고    scopus 로고
    • Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of Multiple Hematopoietic Lineages
    • Gabrilovich D, Ishida T, Oyama T, Ran S, Kravtsov V, Nadaf S, Carbone DP. Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of Multiple Hematopoietic Lineages. In Vivo Blood. 1998; 92:4150-4166.
    • (1998) In Vivo Blood. , vol.92 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3    Ran, S.4    Kravtsov, V.5    Nadaf, S.6    Carbone, D.P.7
  • 22
    • 84891612009 scopus 로고    scopus 로고
    • Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma
    • Iannone R, Miele L, Maiolino P, Pinto A, Morello S. Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma. Neoplasia. 2013; 15:1400-1409.
    • (2013) Neoplasia. , vol.15 , pp. 1400-1409
    • Iannone, R.1    Miele, L.2    Maiolino, P.3    Pinto, A.4    Morello, S.5
  • 23
    • 84899084303 scopus 로고    scopus 로고
    • Targeting the adenosine A2b receptor in the tumor microenvironment overcomes local immunosuppression by myeloid-derived suppressor cells
    • Morello S, Miele L. Targeting the adenosine A2b receptor in the tumor microenvironment overcomes local immunosuppression by myeloid-derived suppressor cells. Oncoimmunology. 2014; 3:e27989.
    • (2014) Oncoimmunology. , vol.3
    • Morello, S.1    Miele, L.2
  • 24
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression
    • Serafini P, Borrello I, Bronte V. Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin Cancer Biol. 2006; 16:53-65.
    • (2006) Semin Cancer Biol. , vol.16 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 25
    • 84862143053 scopus 로고    scopus 로고
    • Melanoma-induced immunosuppression and its neutralization
    • Umansky V, Sevko A. Melanoma-induced immunosuppression and its neutralization. Semin Cancer Biol. 2012; 22:319-326.
    • (2012) Semin Cancer Biol. , vol.22 , pp. 319-326
    • Umansky, V.1    Sevko, A.2
  • 26
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009; 9:162-174.
    • (2009) Nat Rev Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 27
    • 55849114101 scopus 로고    scopus 로고
    • A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    • Eckle T, Grenz A, Laucher S, Eltzschig HK. A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice. J Clin Invest. 2008; 118:3301-3315.
    • (2008) J Clin Invest. , vol.118 , pp. 3301-3315
    • Eckle, T.1    Grenz, A.2    Laucher, S.3    Eltzschig, H.K.4
  • 28
    • 64249107208 scopus 로고    scopus 로고
    • Cutting Edge: A2B Adenosine receptor signaling provides potent protection during intestinal ischemia/reperfusion injury
    • Hart ML, Jacobi B, Schittenhelm J, Henn M, Eltzschig HK. Cutting Edge: A2B Adenosine receptor signaling provides potent protection during intestinal ischemia/reperfusion injury. J Immunol. 2009; 182:3965-3968.
    • (2009) J Immunol. , vol.182 , pp. 3965-3968
    • Hart, M.L.1    Jacobi, B.2    Schittenhelm, J.3    Henn, M.4    Eltzschig, H.K.5
  • 29
    • 0027960791 scopus 로고
    • Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression
    • Hlatky L, Tsionou C, Hahnfeldt P, Coleman CN. Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression. Cancer Res. 1994; 54:6083-6086.
    • (1994) Cancer Res. , vol.54 , pp. 6083-6086
    • Hlatky, L.1    Tsionou, C.2    Hahnfeldt, P.3    Coleman, C.N.4
  • 32
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res. 2005; 11:6713-6721.
    • (2005) Clin Cancer Res. , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 33
    • 67349133537 scopus 로고    scopus 로고
    • Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice
    • Le HK, Graham L, Cha E, Morales JK, Manjili MH, Bear HD. Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice. Int Immunopharmacol. 2009; 9:900-909.
    • (2009) Int Immunopharmacol. , vol.9 , pp. 900-909
    • Le, H.K.1    Graham, L.2    Cha, E.3    Morales, J.K.4    Manjili, M.H.5    Bear, H.D.6
  • 35
    • 39549102220 scopus 로고    scopus 로고
    • STAT3: a critical transcription activator in angiogenesis
    • Chen Z, Han ZC. STAT3: a critical transcription activator in angiogenesis. Med Res Rev. 2008; 28:185-200.
    • (2008) Med Res Rev. , vol.28 , pp. 185-200
    • Chen, Z.1    Han, Z.C.2
  • 38
    • 77954730368 scopus 로고    scopus 로고
    • A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy
    • Pang M, Ma L, Gong R, Tolbert E, Mao H, Ponnusamy M, Chin YE, Yan H, Dworkin LD, Zhuang S. A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy. Kidney Int. 2010; 78:257-268.
    • (2010) Kidney Int. , vol.78 , pp. 257-268
    • Pang, M.1    Ma, L.2    Gong, R.3    Tolbert, E.4    Mao, H.5    Ponnusamy, M.6    Chin, Y.E.7    Yan, H.8    Dworkin, L.D.9    Zhuang, S.10
  • 39
    • 84856015015 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis
    • Sen N, Che X, Rajamani J, Zerboni L, Sung P, Ptacek J, Arvin AM. Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis. Proc Natl Acad Sci U S A. 2012; 109:600-605.
    • (2012) Proc Natl Acad Sci U S A. , vol.109 , pp. 600-605
    • Sen, N.1    Che, X.2    Rajamani, J.3    Zerboni, L.4    Sung, P.5    Ptacek, J.6    Arvin, A.M.7
  • 42
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: basic science and clinical progress
    • Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev. 2004; 25:581-611.
    • (2004) Endocr Rev. , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 43
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and Pharmacodynamics of Bevacizumab as Monotherapy or in Combination with Cytotoxic Therapy in Preclinical Studies
    • Gerber HP, Ferrara N. Pharmacology and Pharmacodynamics of Bevacizumab as Monotherapy or in Combination with Cytotoxic Therapy in Preclinical Studies. Cancer Res. 2005; 65:671-680.
    • (2005) Cancer Res. , vol.65 , pp. 671-680
    • Gerber, H.P.1    Ferrara, N.2
  • 46
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer. 2008; 8:592-603.
    • (2008) Nat. Rev. Cancer. , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 47
    • 61349158530 scopus 로고    scopus 로고
    • T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
    • Sitkovsky MV. T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response. Trends Immunol. 2009; 30:102-108.
    • (2009) Trends Immunol. , vol.30 , pp. 102-108
    • Sitkovsky, M.V.1


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