Differential ASC requirements reveal a key role for neutrophils and a noncanonical IL-1β response to Pseudomonas aeruginosa

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 309, Issue 8, 2015, Pages L902-L913

  Patankar, Yash R ^a   Mabaera, Rodwell ^a   Berwin, Brent ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

ASC; Inflammation; Interleukin 1 ; Neutrophils; Pseudomonas aeruginosa

Indexed keywords

APOPTOSIS ASSOCIATED SPECKLIKE PROTEIN CONTAINING A CASPASE RECRUITMENT DOMAIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; IPAF PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; IN VITRO STUDY; LOBAR PNEUMONIA; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; TYPE III SECRETION SYSTEM; ANIMAL; BACTERIAL PNEUMONIA; BIOSYNTHESIS; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MICROBIOLOGY; PATHOGENICITY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; DISEASE MODELS, ANIMAL; IN VITRO TECHNIQUES; INFLAMMASOMES; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; PERITONITIS; PNEUMONIA, BACTERIAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 84944453679     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00228.2015     Document Type: Article

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