메뉴 건너뛰기




Volumn 45, Issue 12, 2015, Pages 797-808

The HFE genotype and a formulated diet controlling for iron status attenuate experimental cerebral malaria in mice

Author keywords

Epo; IL 6; Iron; Malaria; Myelin; Sema4A

Indexed keywords

BRAIN; DIET; GENOTYPE; IRON; MALARIA; MORBIDITY; NEUROLOGY; PROTEIN; RODENT;

EID: 84944441241     PISSN: 00207519     EISSN: 18790135     Source Type: Journal    
DOI: 10.1016/j.ijpara.2015.07.003     Document Type: Article
Times cited : (6)

References (80)
  • 1
    • 84908365787 scopus 로고    scopus 로고
    • Update: malaria, U.S. Armed Forces, 2013
    • AFHSC Update: malaria, U.S. Armed Forces, 2013. MSMR 2014, 21:4-7.
    • (2014) MSMR , vol.21 , pp. 4-7
  • 3
    • 0034056566 scopus 로고    scopus 로고
    • Effectiveness and strategies of iron supplementation during pregnancy
    • Beard J.L. Effectiveness and strategies of iron supplementation during pregnancy. Am. J. Clin. Nutr. 2000, 71:1288S-1294S.
    • (2000) Am. J. Clin. Nutr. , vol.71 , pp. 1288S-1294S
    • Beard, J.L.1
  • 4
    • 0344395069 scopus 로고    scopus 로고
    • Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats
    • Beard J.L., Wiesinger J.A., Connor J.R. Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats. Dev. Neurosci. 2003, 25:308-315.
    • (2003) Dev. Neurosci. , vol.25 , pp. 308-315
    • Beard, J.L.1    Wiesinger, J.A.2    Connor, J.R.3
  • 6
    • 42649093779 scopus 로고    scopus 로고
    • Artesunate-erythropoietin combination for murine cerebral malaria treatment
    • Bienvenu A.L., Ferrandiz J., Kaiser K., Latour C., Picot S. Artesunate-erythropoietin combination for murine cerebral malaria treatment. Acta Trop. 2008, 106:104-108.
    • (2008) Acta Trop. , vol.106 , pp. 104-108
    • Bienvenu, A.L.1    Ferrandiz, J.2    Kaiser, K.3    Latour, C.4    Picot, S.5
  • 7
    • 0037954281 scopus 로고    scopus 로고
    • HFE, the MHC and hemochromatosis: paradigm for an extended function for MHC class I
    • Cardoso C.S., de Sousa M. HFE, the MHC and hemochromatosis: paradigm for an extended function for MHC class I. Tissue Antigens 2003, 61:263-275.
    • (2003) Tissue Antigens , vol.61 , pp. 263-275
    • Cardoso, C.S.1    de Sousa, M.2
  • 10
    • 84904656232 scopus 로고    scopus 로고
    • Influence of host iron status on Plasmodium falciparum infection
    • Clark M.A., Goheen M.M., Cerami C. Influence of host iron status on Plasmodium falciparum infection. Front. Pharmacol. 2014, 5:84.
    • (2014) Front. Pharmacol. , vol.5 , pp. 84
    • Clark, M.A.1    Goheen, M.M.2    Cerami, C.3
  • 14
    • 0033634877 scopus 로고    scopus 로고
    • HFE - A novel nonclassical class I molecule that is involved in iron metabolism
    • Ehrlich R., Lemonnier F.A. HFE - A novel nonclassical class I molecule that is involved in iron metabolism. Immunity 2000, 13:585-588.
    • (2000) Immunity , vol.13 , pp. 585-588
    • Ehrlich, R.1    Lemonnier, F.A.2
  • 16
    • 64049100955 scopus 로고    scopus 로고
    • Iron in innate immunity: starve the invaders
    • Ganz T. Iron in innate immunity: starve the invaders. Curr. Opin. Immunol. 2009, 21:63-67.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 63-67
    • Ganz, T.1
  • 17
    • 0035154276 scopus 로고    scopus 로고
    • A review of studies on the effect of iron deficiency on cognitive development in children
    • Discussion 666S-668S
    • Grantham-McGregor S., Ani C. A review of studies on the effect of iron deficiency on cognitive development in children. J. Nutr. 2001, 131:649S-666S. Discussion 666S-668S.
    • (2001) J. Nutr. , vol.131 , pp. 649S-666S
    • Grantham-McGregor, S.1    Ani, C.2
  • 18
    • 80053276009 scopus 로고    scopus 로고
    • CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin
    • Hempel C., Combes V., Hunt N.H., Kurtzhals J.A., Grau G.E. CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin. Am. J. Pathol. 2011, 179:1939-1950.
    • (2011) Am. J. Pathol. , vol.179 , pp. 1939-1950
    • Hempel, C.1    Combes, V.2    Hunt, N.H.3    Kurtzhals, J.A.4    Grau, G.E.5
  • 19
    • 84862771113 scopus 로고    scopus 로고
    • Erythropoietin treatment alleviates ultrastructural myelin changes induced by murine cerebral malaria
    • Hempel C., Hyttel P., Staalsø T., Nyengaard J.R., Kurtzhals J.A. Erythropoietin treatment alleviates ultrastructural myelin changes induced by murine cerebral malaria. Malar. J. 2012, 11:216.
    • (2012) Malar. J. , vol.11 , pp. 216
    • Hempel, C.1    Hyttel, P.2    Staalsø, T.3    Nyengaard, J.R.4    Kurtzhals, J.A.5
  • 20
    • 0041378119 scopus 로고    scopus 로고
    • Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria
    • Hunt N.H., Grau G.E. Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends Immunol. 2003, 24:491-499.
    • (2003) Trends Immunol. , vol.24 , pp. 491-499
    • Hunt, N.H.1    Grau, G.E.2
  • 22
    • 77957288323 scopus 로고    scopus 로고
    • Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome
    • Idro R., Marsh K., John C.C., Newton C.R. Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome. Pediatr. Res. 2010, 68:267-274.
    • (2010) Pediatr. Res. , vol.68 , pp. 267-274
    • Idro, R.1    Marsh, K.2    John, C.C.3    Newton, C.R.4
  • 23
    • 0018625631 scopus 로고
    • Cerebral malaria in the United Kingdom
    • Janota I., Doshi B. Cerebral malaria in the United Kingdom. J. Clin. Pathol. 1979, 32:769-772.
    • (1979) J. Clin. Pathol. , vol.32 , pp. 769-772
    • Janota, I.1    Doshi, B.2
  • 27
    • 35448938485 scopus 로고    scopus 로고
    • Association of hemochromatosis with infectious diseases: expanding spectrum
    • Khan F.A., Fisher M.A., Khakoo R.A. Association of hemochromatosis with infectious diseases: expanding spectrum. Int. J. Infect. Dis. 2007, 11:482-487.
    • (2007) Int. J. Infect. Dis. , vol.11 , pp. 482-487
    • Khan, F.A.1    Fisher, M.A.2    Khakoo, R.A.3
  • 31
    • 0032478524 scopus 로고    scopus 로고
    • Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
    • Lebrón J.A., Bennett M.J., Vaughn D.E., Chirino A.J., Snow P.M., Mintier G.A., Feder J.N., Bjorkman P.J. Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell 1998, 93:111-123.
    • (1998) Cell , vol.93 , pp. 111-123
    • Lebrón, J.A.1    Bennett, M.J.2    Vaughn, D.E.3    Chirino, A.J.4    Snow, P.M.5    Mintier, G.A.6    Feder, J.N.7    Bjorkman, P.J.8
  • 32
    • 84930466009 scopus 로고    scopus 로고
    • Semaphorin4A is cytotoxic to oligodendrocytes and is elevated in microglia and multiple sclerosis
    • Leitner D.F., Todorich B., Zhang X., Connor J.R. Semaphorin4A is cytotoxic to oligodendrocytes and is elevated in microglia and multiple sclerosis. ASN Neuro 2015, 7:1-13.
    • (2015) ASN Neuro , vol.7 , pp. 1-13
    • Leitner, D.F.1    Todorich, B.2    Zhang, X.3    Connor, J.R.4
  • 33
    • 33845980588 scopus 로고    scopus 로고
    • Chemokine CXCL12 induces binding of ferritin heavy chain to the chemokine receptor CXCR4, alters CXCR4 signaling, and induces phosphorylation and nuclear translocation of ferritin heavy chain
    • Li R., Luo C., Mines M., Zhang J., Fan G.H. Chemokine CXCL12 induces binding of ferritin heavy chain to the chemokine receptor CXCR4, alters CXCR4 signaling, and induces phosphorylation and nuclear translocation of ferritin heavy chain. J. Biol. Chem. 2006, 281:37616-37627.
    • (2006) J. Biol. Chem. , vol.281 , pp. 37616-37627
    • Li, R.1    Luo, C.2    Mines, M.3    Zhang, J.4    Fan, G.H.5
  • 36
    • 4644337572 scopus 로고    scopus 로고
    • Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls
    • Lyke K.E., Burges R., Cissoko Y., Sangare L., Dao M., Diarra I., Kone A., Harley R., Plowe C.V., Doumbo O.K., Sztein M.B. Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls. Infect. Immun. 2004, 72:5630-5637.
    • (2004) Infect. Immun. , vol.72 , pp. 5630-5637
    • Lyke, K.E.1    Burges, R.2    Cissoko, Y.3    Sangare, L.4    Dao, M.5    Diarra, I.6    Kone, A.7    Harley, R.8    Plowe, C.V.9    Doumbo, O.K.10    Sztein, M.B.11
  • 37
    • 0031081451 scopus 로고    scopus 로고
    • Compromised blood-nerve barrier, astrogliosis, and myelin disruption in optic nerves during fatal murine cerebral malaria
    • Ma N., Madigan M.C., Chan-Ling T., Hunt N.H. Compromised blood-nerve barrier, astrogliosis, and myelin disruption in optic nerves during fatal murine cerebral malaria. Glia 1997, 19:135-151.
    • (1997) Glia , vol.19 , pp. 135-151
    • Ma, N.1    Madigan, M.C.2    Chan-Ling, T.3    Hunt, N.H.4
  • 38
    • 0036413580 scopus 로고    scopus 로고
    • Erythropoietin resistance: the role of inflammation and pro-inflammatory cytokines
    • Macdougall I.C., Cooper A.C. Erythropoietin resistance: the role of inflammation and pro-inflammatory cytokines. Nephrol. Dial. Transplant. 2002, 17(Suppl. 11):39-43.
    • (2002) Nephrol. Dial. Transplant. , vol.17 , pp. 39-43
    • Macdougall, I.C.1    Cooper, A.C.2
  • 39
    • 0035070574 scopus 로고    scopus 로고
    • Central nervous system in cerebral malaria: 'Innocent bystander' or active participant in the induction of immunopathology?
    • Medana I.M., Chaudhri G., Chan-Ling T., Hunt N.H. Central nervous system in cerebral malaria: 'Innocent bystander' or active participant in the induction of immunopathology?. Immunol. Cell Biol. 2001, 79:101-120.
    • (2001) Immunol. Cell Biol. , vol.79 , pp. 101-120
    • Medana, I.M.1    Chaudhri, G.2    Chan-Ling, T.3    Hunt, N.H.4
  • 42
    • 0031909455 scopus 로고    scopus 로고
    • A functional defect in hereditary haemochromatosis monocytes and monocyte-derived macrophages
    • Moura E., Verheul A.F., Marx J.J. A functional defect in hereditary haemochromatosis monocytes and monocyte-derived macrophages. Eur. J. Clin. Invest. 1998, 28:164-173.
    • (1998) Eur. J. Clin. Invest. , vol.28 , pp. 164-173
    • Moura, E.1    Verheul, A.F.2    Marx, J.J.3
  • 43
    • 84856317888 scopus 로고    scopus 로고
    • The pleiotropic effects of erythropoietin in infection and inflammation
    • Nairz M., Sonnweber T., Schroll A., Theurl I., Weiss G. The pleiotropic effects of erythropoietin in infection and inflammation. Microbes Infect. 2012, 14:238-246.
    • (2012) Microbes Infect. , vol.14 , pp. 238-246
    • Nairz, M.1    Sonnweber, T.2    Schroll, A.3    Theurl, I.4    Weiss, G.5
  • 44
    • 84861110359 scopus 로고    scopus 로고
    • Elevation of Sema4A implicates Th cell skewing and the efficacy of IFN-β therapy in multiple sclerosis
    • Nakatsuji Y., et al. Elevation of Sema4A implicates Th cell skewing and the efficacy of IFN-β therapy in multiple sclerosis. J. Immunol. 2012, 188:4858-4865.
    • (2012) J. Immunol. , vol.188 , pp. 4858-4865
    • Nakatsuji, Y.1
  • 45
    • 84875082623 scopus 로고    scopus 로고
    • A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice
    • Nandar W., Neely E.B., Unger E., Connor J.R. A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice. Biochim. Biophys. Acta 2013, 1832:729-741.
    • (2013) Biochim. Biophys. Acta , vol.1832 , pp. 729-741
    • Nandar, W.1    Neely, E.B.2    Unger, E.3    Connor, J.R.4
  • 46
    • 0026746246 scopus 로고
    • Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice
    • Neill A.L., Hunt N.H. Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice. Parasitology 1992, 105(Pt. 2):165-175.
    • (1992) Parasitology , vol.105 , pp. 165-175
    • Neill, A.L.1    Hunt, N.H.2
  • 47
    • 0015857284 scopus 로고
    • Myelination in rat brain: method of myelin isolation
    • Norton W.T., Poduslo S.E. Myelination in rat brain: method of myelin isolation. J. Neurochem. 1973, 21:749-757.
    • (1973) J. Neurochem. , vol.21 , pp. 749-757
    • Norton, W.T.1    Poduslo, S.E.2
  • 48
    • 70049105108 scopus 로고    scopus 로고
    • Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas
    • Ojukwu J.U., Okebe J.U., Yahav D., Paul M. Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas. Cochrane Database Syst. Rev. 2009, CD006589.
    • (2009) Cochrane Database Syst. Rev. , pp. CD006589
    • Ojukwu, J.U.1    Okebe, J.U.2    Yahav, D.3    Paul, M.4
  • 50
    • 4444273210 scopus 로고    scopus 로고
    • Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models
    • Ortiz E., Pasquini J.M., Thompson K., Felt B., Butkus G., Beard J., Connor J.R. Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models. J. Neurosci. Res. 2004, 77:681-689.
    • (2004) J. Neurosci. Res. , vol.77 , pp. 681-689
    • Ortiz, E.1    Pasquini, J.M.2    Thompson, K.3    Felt, B.4    Butkus, G.5    Beard, J.6    Connor, J.R.7
  • 51
    • 0017799101 scopus 로고
    • The effects of therapy on the developmental scores of iron-deficient infants
    • Oski F.A., Honig A.S. The effects of therapy on the developmental scores of iron-deficient infants. J. Pediatr. 1978, 92:21-25.
    • (1978) J. Pediatr. , vol.92 , pp. 21-25
    • Oski, F.A.1    Honig, A.S.2
  • 52
    • 0020532206 scopus 로고
    • Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants
    • Oski F.A., Honig A.S., Helu B., Howanitz P. Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants. Pediatrics 1983, 71:877-880.
    • (1983) Pediatrics , vol.71 , pp. 877-880
    • Oski, F.A.1    Honig, A.S.2    Helu, B.3    Howanitz, P.4
  • 53
    • 33845245942 scopus 로고    scopus 로고
    • Suppression of hepcidin during anemia requires erythropoietic activity
    • Pak M., Lopez M.A., Gabayan V., Ganz T., Rivera S. Suppression of hepcidin during anemia requires erythropoietic activity. Blood 2006, 108:3730-3735.
    • (2006) Blood , vol.108 , pp. 3730-3735
    • Pak, M.1    Lopez, M.A.2    Gabayan, V.3    Ganz, T.4    Rivera, S.5
  • 54
    • 77954653333 scopus 로고    scopus 로고
    • CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination
    • Patel J.R., McCandless E.E., Dorsey D., Klein R.S. CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:11062-11067.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 11062-11067
    • Patel, J.R.1    McCandless, E.E.2    Dorsey, D.3    Klein, R.S.4
  • 56
    • 0028264088 scopus 로고
    • Haemochromatosis as a window into the study of the immunological system: a novel correlation between CD8+ lymphocytes and iron overload
    • Porto G., Reimão R., Gonçalves C., Vicente C., Justiça B., de Sousa M. Haemochromatosis as a window into the study of the immunological system: a novel correlation between CD8+ lymphocytes and iron overload. Eur. J. Haematol. 1994, 52:283-290.
    • (1994) Eur. J. Haematol. , vol.52 , pp. 283-290
    • Porto, G.1    Reimão, R.2    Gonçalves, C.3    Vicente, C.4    Justiça, B.5    de Sousa, M.6
  • 57
    • 57349160468 scopus 로고    scopus 로고
    • Iron metabolism, malaria, and other infections: what is all the fuss about?
    • Prentice A.M. Iron metabolism, malaria, and other infections: what is all the fuss about?. J. Nutr. 2008, 138:2537-2541.
    • (2008) J. Nutr. , vol.138 , pp. 2537-2541
    • Prentice, A.M.1
  • 58
    • 0037055997 scopus 로고    scopus 로고
    • Ferritin induction protects cortical astrocytes from heme-mediated oxidative injury
    • Regan R.F., Kumar N., Gao F., Guo Y. Ferritin induction protects cortical astrocytes from heme-mediated oxidative injury. Neuroscience 2002, 113:985-994.
    • (2002) Neuroscience , vol.113 , pp. 985-994
    • Regan, R.F.1    Kumar, N.2    Gao, F.3    Guo, Y.4
  • 59
    • 0020016101 scopus 로고
    • Cerebral malaria in inbred mice. I. A new model and its pathology
    • Rest J.R. Cerebral malaria in inbred mice. I. A new model and its pathology. Trans. R. Soc. Trop. Med. Hyg. 1982, 76:410-415.
    • (1982) Trans. R. Soc. Trop. Med. Hyg. , vol.76 , pp. 410-415
    • Rest, J.R.1
  • 61
    • 30444459334 scopus 로고    scopus 로고
    • Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial
    • Sazawal S., Black R.E., Ramsan M., Chwaya H.M., Stoltzfus R.J., Dutta A., Dhingra U., Kabole I., Deb S., Othman M.K., Kabole F.M. Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial. Lancet 2006, 367:133-143.
    • (2006) Lancet , vol.367 , pp. 133-143
    • Sazawal, S.1    Black, R.E.2    Ramsan, M.3    Chwaya, H.M.4    Stoltzfus, R.J.5    Dutta, A.6    Dhingra, U.7    Kabole, I.8    Deb, S.9    Othman, M.K.10    Kabole, F.M.11
  • 62
    • 84859739036 scopus 로고    scopus 로고
    • Ferritin stimulates oligodendrocyte genesis in the adult spinal cord and can be transferred from macrophages to NG2 cells in vivo
    • Schonberg D.L., Goldstein E.Z., Sahinkaya F.R., Wei P., Popovich P.G., McTigue D.M. Ferritin stimulates oligodendrocyte genesis in the adult spinal cord and can be transferred from macrophages to NG2 cells in vivo. J. Neurosci. 2012, 32:5374-5384.
    • (2012) J. Neurosci. , vol.32 , pp. 5374-5384
    • Schonberg, D.L.1    Goldstein, E.Z.2    Sahinkaya, F.R.3    Wei, P.4    Popovich, P.G.5    McTigue, D.M.6
  • 64
    • 15044338866 scopus 로고    scopus 로고
    • The global distribution of clinical episodes of Plasmodium falciparum malaria
    • Snow R.W., Guerra C.A., Noor A.M., Myint H.Y., Hay S.I. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 2005, 434:214-217.
    • (2005) Nature , vol.434 , pp. 214-217
    • Snow, R.W.1    Guerra, C.A.2    Noor, A.M.3    Myint, H.Y.4    Hay, S.I.5
  • 66
    • 79954616688 scopus 로고    scopus 로고
    • H-ferritin is the major source of iron for oligodendrocytes
    • Todorich B., Zhang X., Connor J.R. H-ferritin is the major source of iron for oligodendrocytes. Glia 2011, 59:927-935.
    • (2011) Glia , vol.59 , pp. 927-935
    • Todorich, B.1    Zhang, X.2    Connor, J.R.3
  • 69
    • 0037093202 scopus 로고    scopus 로고
    • Regulation of ferritin genes and protein
    • Torti F.M., Torti S.V. Regulation of ferritin genes and protein. Blood 2002, 99:3505-3516.
    • (2002) Blood , vol.99 , pp. 3505-3516
    • Torti, F.M.1    Torti, S.V.2
  • 70
    • 0021673713 scopus 로고
    • Functional defects in phagocytic cells from patients with iron overload
    • van Asbeck B.S., Marx J.J., Struyvenberg A., Verhoef J. Functional defects in phagocytic cells from patients with iron overload. J. Infect. 1984, 8:232-240.
    • (1984) J. Infect. , vol.8 , pp. 232-240
    • van Asbeck, B.S.1    Marx, J.J.2    Struyvenberg, A.3    Verhoef, J.4
  • 72
    • 53149123286 scopus 로고    scopus 로고
    • Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation
    • Wang L., Johnson E.E., Shi H.N., Walker W.A., Wessling-Resnick M., Cherayil B.J. Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. J. Immunol. 2008, 181:2723-2731.
    • (2008) J. Immunol. , vol.181 , pp. 2723-2731
    • Wang, L.1    Johnson, E.E.2    Shi, H.N.3    Walker, W.A.4    Wessling-Resnick, M.5    Cherayil, B.J.6
  • 74
    • 84890848421 scopus 로고    scopus 로고
    • Erythropoietin protects against murine cerebral malaria through actions on host cellular immunity
    • Wei X., Li Y., Sun X., Zhu X., Feng Y., Liu J., Jiang Y., Shang H., Cui L., Cao Y. Erythropoietin protects against murine cerebral malaria through actions on host cellular immunity. Infect. Immun. 2014, 82:165-173.
    • (2014) Infect. Immun. , vol.82 , pp. 165-173
    • Wei, X.1    Li, Y.2    Sun, X.3    Zhu, X.4    Feng, Y.5    Liu, J.6    Jiang, Y.7    Shang, H.8    Cui, L.9    Cao, Y.10
  • 75
    • 77955600573 scopus 로고    scopus 로고
    • Iron homeostasis and the inflammatory response
    • Wessling-Resnick M. Iron homeostasis and the inflammatory response. Annu. Rev. Nutr. 2010, 30:105-122.
    • (2010) Annu. Rev. Nutr. , vol.30 , pp. 105-122
    • Wessling-Resnick, M.1
  • 76
    • 0034068284 scopus 로고    scopus 로고
    • Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster
    • WHO Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster. Trans. R. Soc. Trop. Med. Hyg. 2000, 94(Suppl. 1):S1-S90.
    • (2000) Trans. R. Soc. Trop. Med. Hyg. , vol.94 , pp. S1-S90
  • 77
    • 40149110953 scopus 로고    scopus 로고
    • Recombinant human erythropoietin increases survival and reduces neuronal apoptosis in a murine model of cerebral malaria
    • Wiese L., Hempel C., Penkowa M., Kirkby N., Kurtzhals J.A. Recombinant human erythropoietin increases survival and reduces neuronal apoptosis in a murine model of cerebral malaria. Malar. J. 2008, 7:3.
    • (2008) Malar. J. , vol.7 , pp. 3
    • Wiese, L.1    Hempel, C.2    Penkowa, M.3    Kirkby, N.4    Kurtzhals, J.A.5
  • 78
    • 49749092336 scopus 로고    scopus 로고
    • Anemia of chronic disease: a harmful disorder or an adaptive, beneficial response?
    • Zarychanski R., Houston D.S. Anemia of chronic disease: a harmful disorder or an adaptive, beneficial response?. CMAJ 2008, 179:333-337.
    • (2008) CMAJ , vol.179 , pp. 333-337
    • Zarychanski, R.1    Houston, D.S.2
  • 79
    • 33750535445 scopus 로고    scopus 로고
    • Cellular iron status influences the functional relationship between microglia and oligodendrocytes
    • Zhang X., Surguladze N., Slagle-Webb B., Cozzi A., Connor J.R. Cellular iron status influences the functional relationship between microglia and oligodendrocytes. Glia 2006, 54:795-804.
    • (2006) Glia , vol.54 , pp. 795-804
    • Zhang, X.1    Surguladze, N.2    Slagle-Webb, B.3    Cozzi, A.4    Connor, J.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.