Semaphorin4A is cytotoxic to oligodendrocytes and is elevated in microglia and multiple sclerosis

ASN Neuro

Volumn 7, Issue 3, 2015, Pages

  Leitner, Dominique F ^a   Todorich, Bozho ^b   Zhang, Xuesheng ^a   Connor, James R ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b DUKE UNIVERSITY EYE CENTER   (United States)

Author keywords

H ferritin; Iron; Multiple sclerosis; Oligodendrocyte; Sema4A; Tim2

Indexed keywords

DEFEROXAMINE; FERRITIN; IODINE 125; LIPOPOLYSACCHARIDE; RECEPTOR; RECOMBINANT PROTEIN; SEMAPHORIN 4A; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING 2 RECEPTOR; TRANSFERRIN; UNCLASSIFIED DRUG; APOFERRITIN; IRON; LACTATE DEHYDROGENASE; SEMAPHORIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOTOXICITY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IRON CHELATION; MACROPHAGE; MICROGLIA; MULTIPLE SCLEROSIS; NONHUMAN; OLIGODENDROGLIA; RAT; WESTERN BLOTTING; AGED; ANIMAL; ASTROCYTE; CELL CULTURE; CELL DEATH; CELL LINE; ESCHERICHIA COLI; FEMALE; GENETICS; HUMAN; LYMPHOCYTE; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VERY ELDERLY; WHITE MATTER;

AGED; AGED, 80 AND OVER; ANIMALS; APOFERRITINS; ASTROCYTES; CELL DEATH; CELL LINE; CELLS, CULTURED; ESCHERICHIA COLI; FEMALE; HUMANS; IRON; L-LACTATE DEHYDROGENASE; LYMPHOCYTES; MALE; MICROGLIA; MIDDLE AGED; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SEMAPHORINS; WHITE MATTER;

EID: 84930466009     PISSN: None     EISSN: 17590914     Source Type: Journal    
DOI: 10.1177/1759091415587502     Document Type: Article

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