4-Hydroxynonenal activates Src through a non-canonical pathway that involves EGFR/PTP1B

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 701-707

  Zhang, Hongqiao ^a   Forman, Henry Jay ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

EGFR; lipid peroxidation; protein tyrosine phosphatase; redox signaling; signal transduction; Src kinase

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 HYDROXYNONENAL; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; SMALL INTERFERING RNA; SRC PROTEIN; TYROSINE; UNCLASSIFIED DRUG; 4-HYDROXY-2-NONENAL; ALDEHYDE; EGFR PROTEIN, HUMAN; PTPN1 PROTEIN, HUMAN;

ARTICLE; AUTOPHOSPHORYLATION; CARCINOMA CELL LINE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NON SMALL CELL LUNG CANCER; ONCOGENE SRC; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; WESTERN BLOTTING; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; TUMOR CELL LINE;

ALDEHYDES; BLOTTING, WESTERN; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; OXIDATION-REDUCTION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84944385541     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.08.025     Document Type: Article

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