Low molecular weight protein tyrosine phosphatases: Small, but smart

Cellular and Molecular Life Sciences

Volumn 59, Issue 6, 2002, Pages 941-949

  Raugei, G ^a   Ramponi, G ^a   Chiarugi, P ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cytoskeleton rearrangement; Growth inhibition; LMW PTP; PDGF r; PTP; Redox regulation

Indexed keywords

EPHRIN RECEPTOR; GLUTATHIONE; INSULIN RECEPTOR; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE PHOSPHATASE; TYROSINE KINASE RECEPTOR;

CATALYSIS; CELL DIVISION; CELL GROWTH; DEPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME REGULATION; GROWTH INHIBITION; GROWTH REGULATION; HUMAN; MOLECULAR WEIGHT; MYOBLAST; NONHUMAN; OXIDATION; OXIDATION REDUCTION STATE; RECEPTOR DOWN REGULATION; REVIEW; SEQUENCE HOMOLOGY;

ANIMALS; CELL PHYSIOLOGY; DOWN-REGULATION; HUMANS; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR WEIGHT; OXIDATION-REDUCTION; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; STRUCTURE-ACTIVITY RELATIONSHIP; UP-REGULATION;

EID: 0036305442     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-002-8481-z     Document Type: Review

References (61)

1. Receptor protein-tyrosine kinases and their signal transduction pathways
2. Structure and function of the protein tyrosine phosphatases
3. r phosphotyrosine protein phosphatases
4. Cloning, expression and characterisation of a new human low Mr phosphotyrosine protein phosphatase originating by alternative splicing
5. The molecular basis of the differing kinetic behavior of the two low molecular mass phosphotyrosine protein phosphatase isoforms
6. Sequencing, cloning and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatases
7. A novel isoform of the low molecular weight phosphotyrosine phosphatase, LMPTP-C, arising from alternative mRNA splicing
8. The Src and signal transducers and activators of transcription pathways as specific targets for low molecular weight phosphotyrosine-protein phosphatase in platelet-derived growth factor signaling
9. PDGF receptor as a specific in vivo target for low M(r) phosphotyrosine protein phosphatases
10. LMW-PTP is a negative regulator of insulin-mediated mitotic and metabolic signaling
11. Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses
12. Low M(r) phosphotyrosine protein phosphatase activity on fibroblast growth factor receptor is not associated with enzyme translocation
13. The low-molecular-weight phosphotyrosine protein phosphatase, when overexpressed, reduces the mitogenic response to macrophage colony- stimulating factor and tyrosine phosphorylation of its receptor
14. LMW-PTP associates and dephosphorylates Fak interfering with cell motility and spreading
15. The crystal structure of low-molecular-weight phosphotyrosine protein phosphatases
16. Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity
17. pp60v-src phosphorylates and activates low molecular weight phosphotyrosine-protein phosphatases
18. Regulation of the low molecular weight phosphotyrosine phosphatase by phosphorylation at tyrosines 131 and 132
19. r phosphotyrosine protein phosphatase behaves differently when phosphorylated at Tyr131 or Tyr132 by Src kinase
20. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk and Vav
21. Low molecular weight protein-tyrosine phosphatase tyrosine phosphorylation by c-Src during platelet-derived growth factor-induced mitogenesis correlates with its subcellular targeting
22. The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation
23. Low M(r) protein tyrosine phosphatase inhibits growth and migration of vascular smooth muscle cells induced by platelet-derived growth factor
24. Requirement for Rho in integrin signaling
25. Inhibition of RhoGAP activity is sufficient for the induction of Rho- mediated actin reorganization
26. c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation
27. Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c- Src, is the sole p-Tyr mediator of complex formation
28. Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation
29. LMW-PTP exerts a differential regulation on
30. Low molecular weight protein-tyrosine phosphatase controls the rate and the strength of NIH-3T3 cells adhesion through its phosphorylation on tyrosine 131 or 132
31. Protein phosphatases and the regulation of mitogen-activated protein kinase signaling
32. Regulation of matrix metalloproteinase expression in tumor invasion
33. Tyrosine-phosphorylated caveolin is a physiological substrate of the low M(r) protein-tyrosine phosphatases
34. Oligomeric structure of caveolin: Implications for caveolae membrane organization
35. Porcine liver low M(r) phosphotyrosine protein phosphatase: The amino acid sequenze
36. Nitric oxide causes inactivation of the low molecular weight phosphotyrosine protein phosphatases
37. 2
38. Redox regulation of cellular signalling
39. Protein tyrosine phosphatases: Mechanism of catalysis and substrate specificity
40. Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor
41. Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase 1B
42. Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: Evidence for a sulfenic acid intermediate and implications for redox regulation
43. 2 and vanadate in vitro
44. Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation
45. Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
46. Platelet-derived growth factor-induced H(2)O(2) production requires the activation of phosphatidylinositol 3-kinase
47. Inactivation of protein-tyrosine phosphatases as mechanism of UV-induced signal transduction
48. 2 sensing through oxidation of the Yap1 transcription factor
49. Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
50. Cell surface expression of receptor protein tyrosine phosphatase RPTP mu is regulated by cell-cell contact
51. Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density
52. A redox signaling mechanism for density-dependent inhibition of cell growth
53. Low molecular weight protein-tyrosine phosphatase is involved in growth inhibition during cell differentiation
54. LMW-PTP increases cadherin mediated cell-cell adhesion in NIH-3T3. EJB
55. Regulation of proliferation and differentiation of myoblasts derived from adult mouse skeletal muscle by specific isoforms of PDGF
56. A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation
57. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
58. PRL-1 PTPase expression is developmentally regulated with tissue-specific patterns in epithelial tissues
59. Expression of the protein tyrosine phosphatase beta2 gene in mouse erythroleukemia cells induces terminal erythroid differentiation
60. Site-selective dephosphorylation of the platelet-derived growth factor beta-receptor by the receptor-like protein-tyrosine phosphatase DEP-1
61. The novel protein-tyrosine phosphatase PTP20 is a positive regulator of PC12 cell neuronal differentiation