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Volumn 119, Issue , 2015, Pages 16-26

MicroRNA-16 modulates macrophage polarization leading to improved insulin sensitivity in myoblasts

Author keywords

GLUT4; High sucrose diet; Inflammation; Insulin resistance; Macrophage polarization; microRNA

Indexed keywords

ARGINASE 1; BETA INTERFERON; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE TRANSPORTER 4; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MANNOSE RECEPTOR; MANNOSE RECEPTOR C 1; MEF2A PROTEIN; MICRORNA 155; MICRORNA 16; MICRORNA 29B; PALMITIC ACID; PROTEIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ENDOTOXIN; ENDOTOXIN, ESCHERICHIA COLI; FATTY ACID; MICRORNA; MIRN16 MICRORNA, MOUSE; MIRN16 MICRORNA, RAT; RECOMBINANT PROTEIN; SUGAR INTAKE;

EID: 84944326823     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2015.10.004     Document Type: Article
Times cited : (23)

References (79)
  • 1
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • D.M. Mosser, and J.P. Edwards Exploring the full spectrum of macrophage activation Nat. Rev. Immunol. 8 12 2008 958 969
    • (2008) Nat. Rev. Immunol. , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 2
    • 36249032544 scopus 로고    scopus 로고
    • The macrophage: Past, present and future
    • S. Gordon The macrophage: past, present and future Eur. J. Immunol. 37 Suppl. 1 2007 S9 S17
    • (2007) Eur. J. Immunol. , vol.37 , pp. S9-S17
    • Gordon, S.1
  • 3
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: Nomenclature and experimental guidelines
    • P.J. Murray, and et al. Macrophage activation and polarization: nomenclature and experimental guidelines Immunity 41 1 2014 14 20
    • (2014) Immunity , vol.41 , Issue.1 , pp. 14-20
    • Murray, P.J.1
  • 4
    • 84863455384 scopus 로고    scopus 로고
    • Inflammation and type 2 diabetes
    • M.C. Calle, and M.L. Fernandez Inflammation and type 2 diabetes Diabetes Metab. 38 3 2012 183 191
    • (2012) Diabetes Metab. , vol.38 , Issue.3 , pp. 183-191
    • Calle, M.C.1    Fernandez, M.L.2
  • 5
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • M.Y. Donath, and S.E. Shoelson Type 2 diabetes as an inflammatory disease Nat. Rev. Immunol. 11 2 2011 98 107
    • (2011) Nat. Rev. Immunol. , vol.11 , Issue.2 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 6
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • G.M. Reaven Role of insulin resistance in human disease Diabetes 37 12 1988 1595 1607
    • (1988) Diabetes , vol.37 , Issue.12 , pp. 1595-1607
    • Reaven, G.M.1
  • 7
    • 84905453839 scopus 로고    scopus 로고
    • Combination of alcohol and fructose exacerbates metabolic imbalance in terms of hepatic damage, dyslipidemia, and insulin resistance in rats
    • S.M. Alwahsh, and et al. Combination of alcohol and fructose exacerbates metabolic imbalance in terms of hepatic damage, dyslipidemia, and insulin resistance in rats PLoS One 9 8 2014 e104220
    • (2014) PLoS One , vol.9 , Issue.8 , pp. e104220
    • Alwahsh, S.M.1
  • 8
    • 15744394674 scopus 로고    scopus 로고
    • Fructose, insulin resistance, and metabolic dyslipidemia
    • H. Basciano, L. Federico, and K. Adeli Fructose, insulin resistance, and metabolic dyslipidemia Nutr. Metab. (Lond) 2 1 2005 5
    • (2005) Nutr. Metab. (Lond) , vol.2 , Issue.1 , pp. 5
    • Basciano, H.1    Federico, L.2    Adeli, K.3
  • 9
    • 66749154237 scopus 로고    scopus 로고
    • Dietary fructose and glucose differentially affect lipid and glucose homeostasis
    • E.J. Schaefer, J.A. Gleason, and M.L. Dansinger Dietary fructose and glucose differentially affect lipid and glucose homeostasis J. Nutr. 139 6 2009 1257S 1262S
    • (2009) J. Nutr. , vol.139 , Issue.6 , pp. 1257S-1262S
    • Schaefer, E.J.1    Gleason, J.A.2    Dansinger, M.L.3
  • 10
    • 84872156123 scopus 로고    scopus 로고
    • Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice
    • B.W. Parks, and et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice Cell Metab. 17 1 2013 141 152
    • (2013) Cell Metab. , vol.17 , Issue.1 , pp. 141-152
    • Parks, B.W.1
  • 11
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • C.N. Lumeng, J.L. Bodzin, and A.R. Saltiel Obesity induces a phenotypic switch in adipose tissue macrophage polarization J. Clin. Invest 117 1 2007 175 184
    • (2007) J. Clin. Invest , vol.117 , Issue.1 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 12
    • 34548477639 scopus 로고    scopus 로고
    • Adipose tissue macrophages
    • M. Zeyda, and T.M. Stulnig Adipose tissue macrophages Immunol. Lett. 112 2 2007 61 67
    • (2007) Immunol. Lett. , vol.112 , Issue.2 , pp. 61-67
    • Zeyda, M.1    Stulnig, T.M.2
  • 13
    • 4243150843 scopus 로고    scopus 로고
    • The role of TNF-alpha in insulin resistance
    • S.E. Borst The role of TNF-alpha in insulin resistance Endocrine 23 2-3 2004 177 182
    • (2004) Endocrine , vol.23 , Issue.2-3 , pp. 177-182
    • Borst, S.E.1
  • 14
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • J.M. Olefsky, and C.K. Glass Macrophages, inflammation, and insulin resistance Annu. Rev. Physiol. 72 2010 219 246
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 15
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function cell 116 2 2004 281 297
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 16
    • 26944437949 scopus 로고    scopus 로고
    • MicroRNA biogenesis and function in plants
    • X. Chen MicroRNA biogenesis and function in plants FEBS Lett. 579 26 2005 5923 5931
    • (2005) FEBS Lett. , vol.579 , Issue.26 , pp. 5923-5931
    • Chen, X.1
  • 17
    • 70349439320 scopus 로고    scopus 로고
    • MiR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses
    • G. Liu, and et al. miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses Proc. Natl. Acad. Sci. 106 37 2009 15819 15824
    • (2009) Proc. Natl. Acad. Sci. , vol.106 , Issue.37 , pp. 15819-15824
    • Liu, G.1
  • 18
    • 84859891062 scopus 로고    scopus 로고
    • MicroRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophages
    • J. Qi, and et al. microRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophages FEBS Lett. 586 8 2012 1201 1207
    • (2012) FEBS Lett. , vol.586 , Issue.8 , pp. 1201-1207
    • Qi, J.1
  • 20
    • 79953726990 scopus 로고    scopus 로고
    • Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes
    • M. Balasubramanyam, and et al. Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes Mol. Cell. Biochem. 351 1-2 2011 197 205
    • (2011) Mol. Cell. Biochem. , vol.351 , Issue.1-2 , pp. 197-205
    • Balasubramanyam, M.1
  • 21
    • 79952779639 scopus 로고    scopus 로고
    • MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases
    • R. Dai, and S.A. Ahmed MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases Transl. Res. 157 4 2011 163 179
    • (2011) Transl. Res. , vol.157 , Issue.4 , pp. 163-179
    • Dai, R.1    Ahmed, S.A.2
  • 22
    • 84864984120 scopus 로고    scopus 로고
    • MicroRNAs in insulin resistance and obesity
    • M.D. Williams, and G.M. Mitchell MicroRNAs in insulin resistance and obesity Exp. Diabetes Res. 2012 2012 484696
    • (2012) Exp. Diabetes Res. , vol.2012 , pp. 484696
    • Williams, M.D.1    Mitchell, G.M.2
  • 23
    • 4744344777 scopus 로고    scopus 로고
    • Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B
    • S. Sinha, and et al. Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B J. Biol. Chem. 279 40 2004 41294 41301
    • (2004) J. Biol. Chem. , vol.279 , Issue.40 , pp. 41294-41301
    • Sinha, S.1
  • 24
    • 0033812537 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and mTOR mediate lipopolysaccharide-stimulated nitric oxide production in macrophages via interferon-beta
    • S.L. Weinstein, and et al. Phosphatidylinositol 3-kinase and mTOR mediate lipopolysaccharide-stimulated nitric oxide production in macrophages via interferon-beta J. Leukoc. Biol. 67 3 2000 405 414
    • (2000) J. Leukoc. Biol. , vol.67 , Issue.3 , pp. 405-414
    • Weinstein, S.L.1
  • 26
    • 84872975552 scopus 로고    scopus 로고
    • MicroRNAs in immune response and macrophage polarization
    • G. Liu, and E. Abraham MicroRNAs in immune response and macrophage polarization Arterioscler., thromb., Vasc. Biol. 33 2 2013 170 177
    • (2013) Arterioscler., Thromb., Vasc. Biol. , vol.33 , Issue.2 , pp. 170-177
    • Liu, G.1    Abraham, E.2
  • 27
    • 84879118942 scopus 로고    scopus 로고
    • MicroRNA let-7c regulates macrophage polarization
    • S. Banerjee, and et al. MicroRNA let-7c regulates macrophage polarization J. Immunol. 190 12 2013 6542 6549
    • (2013) J. Immunol. , vol.190 , Issue.12 , pp. 6542-6549
    • Banerjee, S.1
  • 28
    • 33846845071 scopus 로고    scopus 로고
    • MicroRNA-155 is induced during the macrophage inflammatory response
    • R.M. O'Connell, and et al. MicroRNA-155 is induced during the macrophage inflammatory response Proc. Natl. Acad. Sci. U. S. A. 104 5 2007 1604 1609
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.5 , pp. 1604-1609
    • O'Connell, R.M.1
  • 29
    • 36849005372 scopus 로고    scopus 로고
    • A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
    • M.T. Nguyen, and et al. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways J. Biol. Chem. 282 48 2007 35279 35292
    • (2007) J. Biol. Chem. , vol.282 , Issue.48 , pp. 35279-35292
    • Nguyen, M.T.1
  • 30
    • 79959845414 scopus 로고    scopus 로고
    • MicroRNAs 103 and 107 regulate insulin sensitivity
    • M. Trajkovski, and et al. MicroRNAs 103 and 107 regulate insulin sensitivity Nature 474 7353 2011 649 653
    • (2011) Nature , vol.474 , Issue.7353 , pp. 649-653
    • Trajkovski, M.1
  • 31
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • G.S. Hotamisligil, N.S. Shargill, and B.M. Spiegelman Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance Science 259 5091 1993 87 91
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 32
    • 0036098188 scopus 로고    scopus 로고
    • Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro
    • J.P. Bastard, and et al. Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro J. Clin. Endocrinol. Metab. 87 5 2002 2084 2089
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , Issue.5 , pp. 2084-2089
    • Bastard, J.P.1
  • 33
    • 84869064162 scopus 로고    scopus 로고
    • Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes
    • S. Díaz-Prado, and et al. Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes BMC Musculoskelet. Disord. 13 1 2012 144
    • (2012) BMC Musculoskelet. Disord. , vol.13 , Issue.1 , pp. 144
    • Díaz-Prado, S.1
  • 34
    • 0023493524 scopus 로고
    • Fructose-induced insulin resistance and hypertension in rats
    • I.-S. Hwang, and et al. Fructose-induced insulin resistance and hypertension in rats Hypertension 10 5 1987 512 516
    • (1987) Hypertension , vol.10 , Issue.5 , pp. 512-516
    • Hwang, I.-S.1
  • 35
    • 0034803828 scopus 로고    scopus 로고
    • Prevention of skeletal muscle insulin resistance by dietary cod protein in high fat-fed rats
    • C. Lavigne, and et al. Prevention of skeletal muscle insulin resistance by dietary cod protein in high fat-fed rats Am. J. Physiol. Endocrinol. Metab. 281 1 2001 E62 E71
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.281 , Issue.1 , pp. E62-E71
    • Lavigne, C.1
  • 36
    • 84899869998 scopus 로고    scopus 로고
    • A novel immunomodulatory function of PHLPP1: Inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages
    • N.P. Alamuru, and et al. A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages J. Leukoc. Biol. 95 5 2014 775 783
    • (2014) J. Leukoc. Biol. , vol.95 , Issue.5 , pp. 775-783
    • Alamuru, N.P.1
  • 37
    • 79959686257 scopus 로고    scopus 로고
    • Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance
    • F. Andreozzi, and et al. Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance Diabetologia 54 7 2011 1879 1887
    • (2011) Diabetologia , vol.54 , Issue.7 , pp. 1879-1887
    • Andreozzi, F.1
  • 38
    • 33745089920 scopus 로고    scopus 로고
    • Ceramide mediates TNF-alpha-induced insulin resistance on GLUT4 gene expression in brown adipocytes
    • S. Fernandez-Veledo, and et al. Ceramide mediates TNF-alpha-induced insulin resistance on GLUT4 gene expression in brown adipocytes Arch. Physiol. Biochem. 112 1 2006 13 22
    • (2006) Arch. Physiol. Biochem. , vol.112 , Issue.1 , pp. 13-22
    • Fernandez-Veledo, S.1
  • 39
    • 0036734285 scopus 로고    scopus 로고
    • Skeletal muscle triglycerides lowering is associated with net improvement of insulin sensitivity, TNF-alpha reduction and GLUT4 expression enhancement
    • G. Mingrone, and et al. Skeletal muscle triglycerides lowering is associated with net improvement of insulin sensitivity, TNF-alpha reduction and GLUT4 expression enhancement Int. J. Obes. Relat. Metab. Disord. 26 9 2002 1165 1172
    • (2002) Int. J. Obes. Relat. Metab. Disord. , vol.26 , Issue.9 , pp. 1165-1172
    • Mingrone, G.1
  • 40
    • 0034717280 scopus 로고    scopus 로고
    • The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter
    • S. Mora, and J.E. Pessin The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter J. Biol. Chem. 275 21 2000 16323 16328
    • (2000) J. Biol. Chem. , vol.275 , Issue.21 , pp. 16323-16328
    • Mora, S.1    Pessin, J.E.2
  • 41
    • 43149104404 scopus 로고    scopus 로고
    • GLUT4 enhancer factor (GEF) interacts with MEF2A and HDAC5 to regulate the GLUT4 promoter in adipocytes
    • D.P. Sparling, and et al. GLUT4 enhancer factor (GEF) interacts with MEF2A and HDAC5 to regulate the GLUT4 promoter in adipocytes J. Biol. Chem. 283 12 2008 7429 7437
    • (2008) J. Biol. Chem. , vol.283 , Issue.12 , pp. 7429-7437
    • Sparling, D.P.1
  • 42
    • 0029041905 scopus 로고
    • Effects of tumour necrosis factor alpha (TNFα) on glucose transport and lipid metabolism of newly-differentiated human fat cells in cell culture
    • H. Hauner, and et al. Effects of tumour necrosis factor alpha (TNFα) on glucose transport and lipid metabolism of newly-differentiated human fat cells in cell culture Diabetologia 38 7 1995 764 771
    • (1995) Diabetologia , vol.38 , Issue.7 , pp. 764-771
    • Hauner, H.1
  • 43
    • 0345166869 scopus 로고    scopus 로고
    • Regulation of the human GLUT4 gene promoter: Interaction between a transcriptional activator and myocyte enhancer factor 2A
    • J.B. Knight, and et al. Regulation of the human GLUT4 gene promoter: interaction between a transcriptional activator and myocyte enhancer factor 2A Proc. Natl. Acad. Sci. 100 25 2003 14725 14730
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , Issue.25 , pp. 14725-14730
    • Knight, J.B.1
  • 44
    • 84856741945 scopus 로고    scopus 로고
    • Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): A new player in cell signaling
    • N.A. Warfel, and A.C. Newton Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling J. Biol. Chem. 287 6 2012 3610 3616
    • (2012) J. Biol. Chem. , vol.287 , Issue.6 , pp. 3610-3616
    • Warfel, N.A.1    Newton, A.C.2
  • 45
    • 84862697885 scopus 로고    scopus 로고
    • Identifying functional microRNAs in macrophages with polarized phenotypes
    • J.W. Graff, and et al. Identifying functional microRNAs in macrophages with polarized phenotypes J. Biol. Chem. 287 26 2012 21816 21825
    • (2012) J. Biol. Chem. , vol.287 , Issue.26 , pp. 21816-21825
    • Graff, J.W.1
  • 46
    • 84908141399 scopus 로고    scopus 로고
    • MiR-15a/16 regulates macrophage phagocytosis after bacterial infection
    • H.-G. Moon, and et al. miR-15a/16 regulates macrophage phagocytosis after bacterial infection J. Immunol. 193 9 2014 4558 4567
    • (2014) J. Immunol. , vol.193 , Issue.9 , pp. 4558-4567
    • Moon, H.-G.1
  • 47
    • 74249084440 scopus 로고    scopus 로고
    • MiR-15a and miR-16-1 in cancer: Discovery, function and future perspectives
    • R. Aqeilan, G. Calin, and C. Croce miR-15a and miR-16-1 in cancer: discovery, function and future perspectives Cell Death Differ. 17 2 2010 215 220
    • (2010) Cell Death Differ. , vol.17 , Issue.2 , pp. 215-220
    • Aqeilan, R.1    Calin, G.2    Croce, C.3
  • 48
    • 18844459384 scopus 로고    scopus 로고
    • MiR-15a and miR-16-1 down-regulation in pituitary adenomas
    • A. Bottoni, and et al. miR-15a and miR-16-1 down-regulation in pituitary adenomas J. Cell. Physiol. 204 1 2005 280 285
    • (2005) J. Cell. Physiol. , vol.204 , Issue.1 , pp. 280-285
    • Bottoni, A.1
  • 49
    • 77955924350 scopus 로고    scopus 로고
    • MicroRNAs modulate the noncanonical NF-κB pathway by regulating IKKα expression during macrophage differentiation
    • T. Li, and et al. MicroRNAs modulate the noncanonical NF-κB pathway by regulating IKKα expression during macrophage differentiation Nat. Immunol. 11 9 2010 799
    • (2010) Nat. Immunol. , vol.11 , Issue.9 , pp. 799
    • Li, T.1
  • 50
    • 84925448101 scopus 로고    scopus 로고
    • Circulating Toll-like receptor 4-responsive microRNA panel in patients with coronary artery disease: Results from prospective and randomized study of treatment with renin-angiotensin system blockade
    • M. Satoh, and et al. Circulating Toll-like receptor 4-responsive microRNA panel in patients with coronary artery disease: results from prospective and randomized study of treatment with renin-angiotensin system blockade Clin. Sci. (Lond) 128 8 2015 483 491
    • (2015) Clin. Sci. (Lond) , vol.128 , Issue.8 , pp. 483-491
    • Satoh, M.1
  • 51
    • 77549083560 scopus 로고    scopus 로고
    • Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer
    • S.I. Grivennikov, and M. Karin Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer Cytokine Growth Factor Rev. 21 1 2010 11 19
    • (2010) Cytokine Growth Factor Rev. , vol.21 , Issue.1 , pp. 11-19
    • Grivennikov, S.I.1    Karin, M.2
  • 52
    • 84860788476 scopus 로고    scopus 로고
    • Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development
    • M.A. Rivas, and et al. Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development Breast Cancer Res. 14 3 2012 R77
    • (2012) Breast Cancer Res. , vol.14 , Issue.3 , pp. R77
    • Rivas, M.A.1
  • 53
    • 84856195948 scopus 로고    scopus 로고
    • MiR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene
    • R. Zhou, and et al. miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene PLoS One 7 1 2012 e30772
    • (2012) PLoS One , vol.7 , Issue.1 , pp. e30772
    • Zhou, R.1
  • 54
    • 84908141399 scopus 로고    scopus 로고
    • MiR-15a/16 regulates macrophage phagocytosis after bacterial infection
    • H.G. Moon, and et al. miR-15a/16 regulates macrophage phagocytosis after bacterial infection J. Immunol. 193 9 2014 4558 4567
    • (2014) J. Immunol. , vol.193 , Issue.9 , pp. 4558-4567
    • Moon, H.G.1
  • 55
    • 20044388720 scopus 로고    scopus 로고
    • Involvement of microRNA in AU-rich element-mediated mRNA instability
    • Q. Jing, and et al. Involvement of microRNA in AU-rich element-mediated mRNA instability Cell 120 5 2005 623 634
    • (2005) Cell , vol.120 , Issue.5 , pp. 623-634
    • Jing, Q.1
  • 56
    • 40949102111 scopus 로고    scopus 로고
    • Post-transcriptional control of cytokine production
    • P. Anderson Post-transcriptional control of cytokine production Nat. Immunol. 9 4 2008 353 359
    • (2008) Nat. Immunol. , vol.9 , Issue.4 , pp. 353-359
    • Anderson, P.1
  • 57
    • 41649097735 scopus 로고    scopus 로고
    • Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality sixteen years of follow-up in US women
    • C. Zhang, and et al. Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality sixteen years of follow-up in US women Circulation 117 13 2008 1658 1667
    • (2008) Circulation , vol.117 , Issue.13 , pp. 1658-1667
    • Zhang, C.1
  • 58
    • 35848935201 scopus 로고    scopus 로고
    • Cause-specific excess deaths associated with underweight, overweight, and obesity
    • K.M. Flegal, and et al. Cause-specific excess deaths associated with underweight, overweight, and obesity Jama 298 17 2007 2028 2037
    • (2007) Jama , vol.298 , Issue.17 , pp. 2028-2037
    • Flegal, K.M.1
  • 59
    • 19044393872 scopus 로고    scopus 로고
    • Adipose tissue, inflammation, and cardiovascular disease
    • A.H. Berg, and P.E. Scherer Adipose tissue, inflammation, and cardiovascular disease Circ. Res. 96 9 2005 939 949
    • (2005) Circ. Res. , vol.96 , Issue.9 , pp. 939-949
    • Berg, A.H.1    Scherer, P.E.2
  • 60
    • 0033984744 scopus 로고    scopus 로고
    • Inflammation, obesity, stress and coronary heart disease: Is interleukin-6 the link?
    • J.S. Yudkin, and et al. Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis 148 2 2000 209 214
    • (2000) Atherosclerosis , vol.148 , Issue.2 , pp. 209-214
    • Yudkin, J.S.1
  • 61
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: The link between insulin resistance, obesity and diabetes
    • P. Dandona, A. Aljada, and A. Bandyopadhyay Inflammation: the link between insulin resistance, obesity and diabetes Trends Immunol. 25 1 2004 4 7
    • (2004) Trends Immunol. , vol.25 , Issue.1 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 62
    • 79960175448 scopus 로고    scopus 로고
    • MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis
    • M. Hulsmans, D. De Keyzer, and P. Holvoet MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis FASEB J. 25 8 2011 2515 2527
    • (2011) FASEB J. , vol.25 , Issue.8 , pp. 2515-2527
    • Hulsmans, M.1    De Keyzer, D.2    Holvoet, P.3
  • 63
    • 77951117713 scopus 로고    scopus 로고
    • Role of microRNAs in obesity and the metabolic syndrome
    • H. Heneghan, N. Miller, and M. Kerin Role of microRNAs in obesity and the metabolic syndrome Obes. Rev. 11 5 2010 354 361
    • (2010) Obes. Rev. , vol.11 , Issue.5 , pp. 354-361
    • Heneghan, H.1    Miller, N.2    Kerin, M.3
  • 64
    • 79958121735 scopus 로고    scopus 로고
    • MicroRNAs in the regulation of adipogenesis and obesity
    • R. McGregor, and M. Choi microRNAs in the regulation of adipogenesis and obesity Curr. Mol. Med. 11 4 2011 304
    • (2011) Curr. Mol. Med. , vol.11 , Issue.4 , pp. 304
    • McGregor, R.1    Choi, M.2
  • 65
    • 41749110910 scopus 로고    scopus 로고
    • Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans
    • A.B. Thrush, and et al. Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans Am. J. Physiol. Regul. Integr. Comp. Physiol. 294 4 2008 p. R1205-12
    • (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.294 , Issue.4 , pp. R1205-R1212
    • Thrush, A.B.1
  • 66
    • 84899630749 scopus 로고    scopus 로고
    • Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and microRNA expression
    • S.E. Olivo-Marston, and et al. Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and microRNA expression PloS One 9 4 2014 e94765
    • (2014) PloS One , vol.9 , Issue.4 , pp. e94765
    • Olivo-Marston, S.E.1
  • 67
    • 84922105005 scopus 로고    scopus 로고
    • Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: Results from studies of twins with and without type 2 diabetes
    • J. Bork-Jensen, and et al. Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes Diabetologia 58 2 2015 363 373
    • (2015) Diabetologia , vol.58 , Issue.2 , pp. 363-373
    • Bork-Jensen, J.1
  • 68
    • 84924872826 scopus 로고    scopus 로고
    • MiR-15b/16 protects primary human retinal microvascular endothelial cells against hyperglycemia-induced increases in tumor necrosis factor alpha and suppressor of cytokine signaling 3
    • E.-A. Ye, and J.J. Steinle miR-15b/16 protects primary human retinal microvascular endothelial cells against hyperglycemia-induced increases in tumor necrosis factor alpha and suppressor of cytokine signaling 3 J. Neuroinflamm. 12 1 2015 44
    • (2015) J. Neuroinflamm. , vol.12 , Issue.1 , pp. 44
    • Ye, E.-A.1    Steinle, J.J.2
  • 69
    • 20044388720 scopus 로고    scopus 로고
    • Involvement of microRNA in AU-rich element-mediated mRNA instability
    • Q. Jing, and et al. Involvement of microRNA in AU-rich element-mediated mRNA instability Cell 120 5 2005 623 634
    • (2005) Cell , vol.120 , Issue.5 , pp. 623-634
    • Jing, Q.1
  • 70
    • 43049179999 scopus 로고    scopus 로고
    • LPS/TLR4 signal transduction pathway
    • Y.-C. Lu, W.-C. Yeh, and P.S. Ohashi LPS/TLR4 signal transduction pathway Cytokine 42 2 2008 145 151
    • (2008) Cytokine , vol.42 , Issue.2 , pp. 145-151
    • Lu, Y.-C.1    Yeh, W.-C.2    Ohashi, P.S.3
  • 71
    • 0742324860 scopus 로고    scopus 로고
    • TLR signaling pathways
    • K. Takeda, and S. Akira TLR signaling pathways Semin. Immunol. 16 1 2004 3 9
    • (2004) Semin. Immunol. , vol.16 , Issue.1 , pp. 3-9
    • Takeda, K.1    Akira, S.2
  • 72
    • 0346243941 scopus 로고    scopus 로고
    • Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
    • T. Ishitani, and et al. Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling EMBO J. 22 23 2003 6277 6288
    • (2003) EMBO J. , vol.22 , Issue.23 , pp. 6277-6288
    • Ishitani, T.1
  • 73
    • 33748797424 scopus 로고    scopus 로고
    • LPS-induced TNF-α factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways
    • X. Tang, and et al. LPS-induced TNF-α factor (LITAF)-deficient mice express reduced LPS-induced cytokine: evidence for LITAF-dependent LPS signaling pathways Proc. Natl. Acad. Sci. 103 37 2006 13777 13782
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , Issue.37 , pp. 13777-13782
    • Tang, X.1
  • 74
    • 84866436241 scopus 로고    scopus 로고
    • MiR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma
    • C.-K. Cai, and et al. miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma Oncol. Rep. 28 5 2012 1764 1770
    • (2012) Oncol. Rep. , vol.28 , Issue.5 , pp. 1764-1770
    • Cai, C.-K.1
  • 75
    • 25444520537 scopus 로고    scopus 로고
    • MiR-15 and miR-16 induce apoptosis by targeting BCL2
    • A. Cimmino, and et al. miR-15 and miR-16 induce apoptosis by targeting BCL2 Proc. Natl. Acad. Sci. U. S. A. 102 39 2005 13944 13949
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , Issue.39 , pp. 13944-13949
    • Cimmino, A.1
  • 76
    • 84903521363 scopus 로고    scopus 로고
    • Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression
    • Y. Lee, and et al. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression Nature 510 7506 2014 547 551
    • (2014) Nature , vol.510 , Issue.7506 , pp. 547-551
    • Lee, Y.1
  • 77
    • 67849091040 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents
    • A. Leitch, C. Haslett, and A. Rossi Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents Br. J. Pharmacol. 158 4 2009 1004 1016
    • (2009) Br. J. Pharmacol. , vol.158 , Issue.4 , pp. 1004-1016
    • Leitch, A.1    Haslett, C.2    Rossi, A.3
  • 78
    • 17744404883 scopus 로고    scopus 로고
    • Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function
    • H. Ueno, and et al. Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function Mol. Biol. Cell 11 2 2000 735 746
    • (2000) Mol. Biol. Cell , vol.11 , Issue.2 , pp. 735-746
    • Ueno, H.1
  • 79
    • 84935844640 scopus 로고    scopus 로고
    • MicroRNA dysregulation in liver and pancreas of CMP-Neu5Ac hydroxylase null mice disrupts insulin/PI3K-AKT signaling
    • D.-N. Kwon, B.-S. Chang, and J.-H. Kim MicroRNA dysregulation in liver and pancreas of CMP-Neu5Ac hydroxylase null mice disrupts insulin/PI3K-AKT signaling BioMed Res. Int. 2014 2014
    • (2014) BioMed Res. Int. , vol.2014
    • Kwon, D.-N.1    Chang, B.-S.2    Kim, J.-H.3


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