MiR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Zhou, Rui ^a   Li, Xiaoqing ^b   Hu, Guoku ^a   Gong, Ai Yu ^a   Drescher, Kristen M ^a   Chen, Xian Ming ^a  

^a CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA; MICRORNA 16; MITOGEN ACTIVATED PROTEIN KINASE; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; UNCLASSIFIED DRUG; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; ENZYME INHIBITOR; FLAVONOID; IL8 PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE; MIRN16 MICRORNA, HUMAN; PYRIDINE DERIVATIVE;

3' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; EPITHELIUM CELL; GENE; GENE REPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IL 8 GENE; MONOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RNA STABILITY; TRANSACTIVATION; CELL CULTURE; CELL STRAIN U937; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANTHRACENES; CELLS, CULTURED; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GENE EXPRESSION REGULATION; HUMANS; IMIDAZOLES; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICRORNAS; NF-KAPPA B; NUCLEAR RECEPTOR CO-REPRESSOR 2; PYRIDINES; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; U937 CELLS;

EID: 84856195948     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030772     Document Type: Article

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