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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 21, 2015, Pages 4922-4926

An unprecedented dual antagonist and agonist of human Transglutaminase 2

(5) Yi, Michael C a Palanski, Brad A b Quintero, Steven A b Plugis, Nicholas M b Khosla, Chaitan a,b

a Stanford University (United States)

b STANFORD UNIVERSITY (United States)

Author keywords

Allostery; Celiac disease; Oxoindole; Transglutaminase 2

Indexed keywords

ACYLIDENEOXOINDOLE DERIVATIVE; ACYLTRANSFERASE INHIBITOR; CALCIUM; INDOLE DERIVATIVE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; TRANSGLUTAMINASE 2 INHIBITOR; UNCLASSIFIED DRUG; ENZYME INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; MUTANT; AGONISTS; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; FIBROBLAST; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FIBROBLASTS; GTP-BINDING PROTEINS; HUMANS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSGLUTAMINASES;

EID: 84944154462 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2015.05.006 Document Type: Article

Times cited : (9)

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