Asexual sporulation facilitates adaptation: The emergence of azole resistance in Aspergillus fumigatus

Evolution

Volumn 69, Issue 10, 2015, Pages 2573-2586

  Zhang, Jianhua ^a   Debets, Alfons J M ^a   Verweij, Paul E ^b   Melchers, Willem J G ^b   Zwaan, Bas J ^a   Schoustra, Sijmen E ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Alternation between unicellular and multicellular growth; Asexual sporulation; Aspergillus fumigatus; Azole resistance; Experimental evolution; MIC value; Mycelial growth rate

Indexed keywords

ADAPTATION; ASEXUAL REPRODUCTION; CONCENTRATION (COMPOSITION); EVOLUTIONARY BIOLOGY; EXPERIMENTAL STUDY; FUNGICIDE; FUNGUS; GROWTH RATE; NATURAL SELECTION; PESTICIDE RESISTANCE; PUBLIC HEALTH; SPORULATION;

ASPERGILLUS FUMIGATUS; FUNGI;

FUNGICIDE; TRIAZOLE DERIVATIVE;

ADAPTATION; ASEXUAL REPRODUCTION; ASPERGILLUS FUMIGATUS; DRUG EFFECTS; EVOLUTION; FUNGAL GENE; GENETIC SELECTION; GENETICS; MULTIDRUG RESISTANCE; MUTATION;

ADAPTATION, BIOLOGICAL; ASPERGILLUS FUMIGATUS; BIOLOGICAL EVOLUTION; DRUG RESISTANCE, MULTIPLE, FUNGAL; FUNGICIDES, INDUSTRIAL; GENES, FUNGAL; MUTATION; REPRODUCTION, ASEXUAL; SELECTION, GENETIC; TRIAZOLES;

EID: 84944152916     PISSN: 00143820     EISSN: 15585646     Source Type: Journal    
DOI: 10.1111/evo.12763     Document Type: Article

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