메뉴 건너뛰기




Volumn 17, Issue 10, 2011, Pages 1846-1854

Clinical implications of azole resistance in Aspergillus fumigatus, The Netherlands, 2007-2009

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; CASPOFUNGIN; ECHINOCANDIN; FLUCONAZOLE; ITRACONAZOLE; POLYENE; POSACONAZOLE; PYRROLE DERIVATIVE; VORICONAZOLE;

EID: 84930481483     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid1710.110226     Document Type: Article
Times cited : (389)

References (37)
  • 1
    • 39449095735 scopus 로고    scopus 로고
    • Treatment of aspergillosis: Clinical practice guidelines of the Infectious Diseases Society of America
    • doi:10.1086/525258
    • Walsh TJ, Anaissie EJ, Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis. 2008;46:327-60.doi:10.1086/525258
    • (2008) Clin Infect Dis , vol.46 , pp. 327-360
    • Walsh, T.J.1    Anaissie, E.J.2    Denning, D.W.3    Herbrecht, R.4    Kontoyiannis, D.P.5    Marr, K.A.6
  • 2
    • 0037043655 scopus 로고    scopus 로고
    • Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis
    • doi:10.1056/NEJMoa020191
    • Herbrecht R, Denning DW, Patterson TF, Bennett JE, Greene RE, Oestmann JW, et al. Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis. N Engl J Med. 2002;347:408-15. doi:10.1056/NEJMoa020191
    • (2002) N Engl J Med , vol.347 , pp. 408-415
    • Herbrecht, R.1    Denning, D.W.2    Patterson, T.F.3    Bennett, J.E.4    Greene, R.E.5    Oestmann, J.W.6
  • 3
    • 0037165259 scopus 로고    scopus 로고
    • Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever
    • doi:10.1056/ NEJM200201243460403
    • Walsh TJ, Pappas P, Winston DJ, Lazarus HM, Petersen F, Raffalli J, et al. Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever. N Engl J Med. 2002;346:225-34. doi:10.1056/ NEJM200201243460403
    • (2002) N Engl J Med , vol.346 , pp. 225-234
    • Walsh, T.J.1    Pappas, P.2    Winston, D.J.3    Lazarus, H.M.4    Petersen, F.5    Raffalli, J.6
  • 4
    • 27144499529 scopus 로고    scopus 로고
    • Improved outcome in central nervous system aspergillosis, using voriconazole treatment
    • doi:10.1182/ blood-2005-02-0733
    • Schwartz S, Ruhnke M, Ribaud P, Corey L, Driscoll T, Cornely OA, et al. Improved outcome in central nervous system aspergillosis, using voriconazole treatment. Blood. 2005;106:2641-5.doi:10.1182/ blood-2005-02-0733
    • (2005) Blood , vol.106 , pp. 2641-2645
    • Schwartz, S.1    Ruhnke, M.2    Ribaud, P.3    Corey, L.4    Driscoll, T.5    Cornely, O.A.6
  • 5
    • 56749174734 scopus 로고    scopus 로고
    • Outcome and medical costs of patients with invasive aspergillosis and acute myelogenous leukemia-myelodysplastic syndrome treated with intensive chemotherapy: An observational study
    • doi:10.1086/591531
    • Slobbe L, Polinder S, Doorduijn JK, Lugtenburg PJ, el Barzouhi A, Steyerberg EW, et al. Outcome and medical costs of patients with invasive aspergillosis and acute myelogenous leukemia-myelodysplastic syndrome treated with intensive chemotherapy: an observational study. Clin Infect Dis. 2008;47:1507-12.doi:10.1086/591531
    • (2008) Clin Infect Dis , vol.47 , pp. 1507-1512
    • Slobbe, L.1    Polinder, S.2    Doorduijn, J.K.3    Lugtenburg, P.J.4    El Barzouhi, A.5    Steyerberg, E.W.6
  • 6
    • 56749159784 scopus 로고    scopus 로고
    • Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism
    • doi:10.1371/journal.pmed.0050219
    • Snelders E, van der Lee HAL, Kuijpers J, Rijs AJMM, Varga J, Samson RA, et al. Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism. PLoS Med. 2008;5:e219. doi:10.1371/journal.pmed.0050219
    • (2008) PLoS Med , vol.5
    • Snelders, E.1    van der Lee, H.A.L.2    Kuijpers, J.3    Rijs, A.J.M.M.4    Varga, J.5    Samson, R.A.6
  • 7
    • 67650657544 scopus 로고    scopus 로고
    • Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure
    • doi:10.3201/eid1507.090043
    • Howard SJ, Cerar D, Anderson MJ, Albarrag A, Fisher MC, Pasqualotto AC, et al. Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure. Emerg Infect Dis. 2009;15:1068-76.doi:10.3201/eid1507.090043
    • (2009) Emerg Infect Dis , vol.15 , pp. 1068-1076
    • Howard, S.J.1    Cerar, D.2    Anderson, M.J.3    Albarrag, A.4    Fisher, M.C.5    Pasqualotto, A.C.6
  • 9
    • 0037180790 scopus 로고    scopus 로고
    • Multidrug resistance in Aspergillus fumigatus
    • doi:10.1056/ NEJM200212263472618
    • Warris A, Weemaes CM, Verweij PE. Multidrug resistance in Aspergillus fumigatus. N Engl J Med. 2002;347:2173-4.doi:10.1056/ NEJM200212263472618
    • (2002) N Engl J Med , vol.347 , pp. 2173-2174
    • Warris, A.1    Weemaes, C.M.2    Verweij, P.E.3
  • 10
    • 34047269418 scopus 로고    scopus 로고
    • Multiple-triazole-resistant aspergillosis
    • doi:10.1056/ NEJMc061720
    • Verweij PE, Mellado E, Melchers WJ. Multiple-triazole-resistant aspergillosis. N Engl J Med. 2007;356:1481-3.doi:10.1056/ NEJMc061720
    • (2007) N Engl J Med , vol.356 , pp. 1481-1483
    • Verweij, P.E.1    Mellado, E.2    Melchers, W.J.3
  • 11
    • 34250223076 scopus 로고    scopus 로고
    • A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations
    • doi:10.1128/AAC.01092-06
    • Mellado E, Garcia-Effron G, Alcázar-Fuoli L, Melchers WJ, Verweij PE, Cuenca-Estrella M, et al. A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations. Antimicrob Agents Chemother. 2007;51:1897-904.doi:10.1128/AAC.01092-06
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 1897-1904
    • Mellado, E.1    Garcia-Effron, G.2    Alcázar-Fuoli, L.3    Melchers, W.J.4    Verweij, P.E.5    Cuenca-Estrella, M.6
  • 13
    • 54049095946 scopus 로고    scopus 로고
    • Establishing in vitro-in vivo correlations for Aspergillus fumigatus: The challenge of azoles versus echinocandins
    • doi:10.1128/ AAC.00190-08
    • Arendrup MC, Perkhofer S, Howard SJ, Garcia-Effron G, Vishukumar A, Perlin D, et al. Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins. Antimicrob Agents Chemother. 2008;52:3504-11.doi:10.1128/ AAC.00190-08
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 3504-3511
    • Arendrup, M.C.1    Perkhofer, S.2    Howard, S.J.3    Garcia-Effron, G.4    Vishukumar, A.5    Perlin, D.6
  • 14
    • 0030659412 scopus 로고    scopus 로고
    • In vitro susceptibility of respiratory isolates of Aspergillus species to itraconazole and amphotericin B acquired resistance to itraconazole
    • doi:10.3109/00365549709011864
    • Chryssanthou E. In vitro susceptibility of respiratory isolates of Aspergillus species to itraconazole and amphotericin B acquired resistance to itraconazole. Scand J Infect Dis. 1997;29:509-12.doi:10.3109/00365549709011864
    • (1997) Scand J Infect Dis , vol.29 , pp. 509-512
    • Chryssanthou, E.1
  • 16
    • 0030824612 scopus 로고    scopus 로고
    • Correlation between in-vitro susceptibility testing to itraconazole and in-vivo outcome of Aspergillus fumigatus infection
    • doi:10.1093/jac/40.3.401
    • Denning DW, Radford SA, Oakley KL, Hall L, Johnson EM, Warnock DW. Correlation between in-vitro susceptibility testing to itraconazole and in-vivo outcome of Aspergillus fumigatus infection. J Antimicrob Chemother. 1997;40:401-14.doi:10.1093/jac/40.3.401
    • (1997) J Antimicrob Chemother , vol.40 , pp. 401-414
    • Denning, D.W.1    Radford, S.A.2    Oakley, K.L.3    Hall, L.4    Johnson, E.M.5    Warnock, D.W.6
  • 17
    • 13244298189 scopus 로고    scopus 로고
    • Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma
    • doi:10.1093/jac/dkh507
    • Chen J, Li H, Li R, Bu D, Wan Z. Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma. J Antimicrob Chemother. 2005;55:31-7 doi:10.1093/jac/dkh507
    • (2005) J Antimicrob Chemother , vol.55 , pp. 31-37
    • Chen, J.1    Li, H.2    Li, R.3    Bu, D.4    Wan, Z.5
  • 18
    • 3042531281 scopus 로고    scopus 로고
    • Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs
    • doi:10.1128/ AAC.48.7.2747-2750.2004
    • Mellado E, Garcia-Effron G, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs. Antimicrob Agents Chemother. 2004;48:2747-50.doi:10.1128/ AAC.48.7.2747-2750.2004
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2747-2750
    • Mellado, E.1    Garcia-Effron, G.2    Alcazar-Fuoli, L.3    Cuenca-Estrella, M.4    Rodriguez-Tudela, J.L.5
  • 19
    • 0037417050 scopus 로고    scopus 로고
    • A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus
    • doi:10.1128/ AAC.47.3.1120-1124.2003
    • Diaz-Guerra TM, Mellado E, Cuenca-Estrella M, Rodriguez-Tudela JL. A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus. Antimicrob Agents Chemother. 2003;47:1120-4.doi:10.1128/ AAC.47.3.1120-1124.2003
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1120-1124
    • Diaz-Guerra, T.M.1    Mellado, E.2    Cuenca-Estrella, M.3    Rodriguez-Tudela, J.L.4
  • 20
    • 70749088981 scopus 로고    scopus 로고
    • Azole resistance in Aspergillus: Proposed nomenclature and breakpoints
    • doi:10.1016/j.drup.2009.09.002
    • Verweij PE, Howard SJ, Melchers WJG, Denning DW. Azole resistance in Aspergillus: proposed nomenclature and breakpoints. Drug Resist Updat. 2009;12:141-7.doi:10.1016/j.drup.2009.09.002
    • (2009) Drug Resist Updat , vol.12 , pp. 141-147
    • Verweij, P.E.1    Howard, S.J.2    Melchers, W.J.G.3    Denning, D.W.4
  • 21
    • 77952597776 scopus 로고    scopus 로고
    • Azole resistance profile of amino acid changes in Aspergillus fumigatus cyp51A based on protein homology modeling
    • doi:10.1128/AAC.01599-09
    • Snelders E. Karawajczyk, Schaftenaar G, Verweij PE, Melchers WJ. Azole resistance profile of amino acid changes in Aspergillus fumigatus cyp51A based on protein homology modeling. Antimicrob Agents Chemother. 2010;54:2425-30.doi:10.1128/AAC.01599-09
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 2425-2430
    • Snelders, E.1    Karawajczyk, S.G.2    Verweij, P.E.3    Melchers, W.J.4
  • 22
    • 34347343785 scopus 로고    scopus 로고
    • Aspergillosis-and a misleading sensitivity result
    • doi:10.1016/S0140-6736(07)61055-1
    • van Leer-Buter C, Takes RP, Hebeda KM, Melchers WJ, Verweij PE. Aspergillosis-and a misleading sensitivity result. Lancet. 2007;370:102.doi:10.1016/S0140-6736(07)61055-1
    • (2007) Lancet , vol.370 , pp. 102
    • van Leer-Buter, C.1    Takes, R.P.2    Hebeda, K.M.3    Melchers, W.J.4    Verweij, P.E.5
  • 24
    • 56749116474 scopus 로고    scopus 로고
    • Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery
    • doi:10.1080/13693780802545600
    • Hodiamont CJ, Dolman KM, ten Berge RJM, Melchers WJ, Verweij PE, Pajkrt D. Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery. Med Mycol. 2009;47:217-20.doi:10.1080/13693780802545600
    • (2009) Med Mycol , vol.47 , pp. 217-220
    • Hodiamont, C.J.1    Dolman, K.M.2    ten Berge, R.J.M.3    Melchers, W.J.4    Verweij, P.E.5    Pajkrt, D.6
  • 25
    • 78049299102 scopus 로고    scopus 로고
    • Impact of cyp51A mutations on the pharmacokinetic and pharmacodynamic properties of voriconazole in a murine model of disseminated aspergillosis
    • doi:10.1128/AAC.00606-10
    • Mavridou E, Brüggemann RJ, Melchers WJ, Verweij PE, Mouton JW. Impact of cyp51A mutations on the pharmacokinetic and pharmacodynamic properties of voriconazole in a murine model of disseminated aspergillosis. Antimicrob Agents Chemother. 2010;54:4758-64.doi:10.1128/AAC.00606-10
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4758-4764
    • Mavridou, E.1    Brüggemann, R.J.2    Melchers, W.J.3    Verweij, P.E.4    Mouton, J.W.5
  • 26
    • 75749102569 scopus 로고    scopus 로고
    • Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene
    • doi:10.1128/AAC.00931-09
    • Mavridou E, Brüggemann RJ, Melchers WJ, Mouton JW, Verweij PE. Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene. Antimicrob Agents Chemother. 2010;54:860-5.doi:10.1128/AAC.00931-09
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 860-865
    • Mavridou, E.1    Brüggemann, R.J.2    Melchers, W.J.3    Mouton, J.W.4    Verweij, P.E.5
  • 27
    • 71549143158 scopus 로고    scopus 로고
    • Azole resistance in Aspergillus fumigatus: A side-effect of environmental fungicide use?
    • doi:10.1016/ S1473-3099(09)70265-8
    • Verweij PE, Snelders E, Kema GH, Mellado E, Melchers WJ. Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use? Lancet Infect Dis. 2009;9:789-95.doi:10.1016/ S1473-3099(09)70265-8
    • (2009) Lancet Infect Dis , vol.9 , pp. 789-795
    • Verweij, P.E.1    Snelders, E.2    Kema, G.H.3    Mellado, E.4    Melchers, W.J.5
  • 28
    • 67149128129 scopus 로고    scopus 로고
    • Possible environmental origin of resistance of Aspergillus fumigatus to medical triazoles
    • doi:10.1128/AEM.00231-09
    • Snelders E, Huisin't Veld RAG, Rijs AJJM, Kema GHJ, Melchers WJ, Verweij PE. Possible environmental origin of resistance of Aspergillus fumigatus to medical triazoles. Appl Environ Microbiol. 2009;75:4053-7.doi:10.1128/AEM.00231-09
    • (2009) Appl Environ Microbiol , vol.75 , pp. 4053-4057
    • Snelders, E.1    Huisin't2    Rijs, A.J.J.M.3    Kema, G.H.J.4    Melchers, W.J.5    Verweij, P.E.6
  • 30
    • 0036305717 scopus 로고    scopus 로고
    • Nationwide survey of in vitro activities of itraconazole and voriconazole against clinical Aspergillus fumigatus isolates cultured between 1945 and 1998
    • doi:10.1128/JCM.40.7.2648-2650.2002
    • Verweij PE, Te Dorsthorst DT, Rijs AJ, De Vries-Hospers HG, Meis JF. Nationwide survey of in vitro activities of itraconazole and voriconazole against clinical Aspergillus fumigatus isolates cultured between 1945 and 1998. J Clin Microbiol. 2002;40:2648-50.doi:10.1128/JCM.40.7.2648-2650.2002
    • (2002) J Clin Microbiol , vol.40 , pp. 2648-2650
    • Verweij, P.E.1    Te Dorsthorst, D.T.2    Rijs, A.J.3    De Vries-Hospers, H.G.4    Meis, J.F.5
  • 31
    • 77953721389 scopus 로고    scopus 로고
    • Novel mixed-format real-time PCR assay to detect mutations conferring resistance to triazoles in Aspergillus fumigatus and prevalence of multi-triazole resistance among clinical isolates in the Netherlands
    • doi:10.1093/jac/dkq041
    • Klaassen CH, de Valk HA, Curfs-Breuker IM, Meis JF. Novel mixed-format real-time PCR assay to detect mutations conferring resistance to triazoles in Aspergillus fumigatus and prevalence of multi-triazole resistance among clinical isolates in the Netherlands. J Antimicrob Chemother. 2010;65:901-5.doi:10.1093/jac/dkq041
    • (2010) J Antimicrob Chemother , vol.65 , pp. 901-905
    • Klaassen, C.H.1    de Valk, H.A.2    Curfs-Breuker, I.M.3    Meis, J.F.4
  • 32
    • 80053253460 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of filamentous fungi; approved standard, 2nd ed, Wayne (PA): The Institute
    • Clinical and Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of filamentous fungi; approved standard, 2nd ed. CLSI document M38-A2. Wayne (PA): The Institute; 2008.
    • (2008) CLSI Document M38-A2
  • 34
    • 0017360990 scopus 로고
    • The measurement of observer agreement for categorical data
    • doi:10.2307/2529310
    • Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159-74.doi:10.2307/2529310
    • (1977) Biometrics , vol.33 , pp. 159-174
    • Landis, J.R.1    Koch, G.G.2
  • 35
    • 70349646099 scopus 로고    scopus 로고
    • Patterns of susceptibility of Aspergillus isolates recovered from patients enrolled in the Transplant-Associated Infection Surveillance Network
    • doi:10.1128/JCM.00854-09
    • Baddley JW, Marr KA, Andes DR, Walsh TJ, Kauffman CA, Kontoyiannis DP, et al. Patterns of susceptibility of Aspergillus isolates recovered from patients enrolled in the Transplant-Associated Infection Surveillance Network. J Clin Microbiol. 2009;47:3271-5.doi:10.1128/JCM.00854-09
    • (2009) J Clin Microbiol , vol.47 , pp. 3271-3275
    • Baddley, J.W.1    Marr, K.A.2    Andes, D.R.3    Walsh, T.J.4    Kauffman, C.A.5    Kontoyiannis, D.P.6
  • 37
    • 79953869925 scopus 로고    scopus 로고
    • High-frequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease
    • doi:10.1093/cid/cir179
    • Denning DW, Park S, Lass-Florl C, Fraczek MG, Kirwan M, Gore R, et al. High-frequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease. Clin Infect Dis. 2011;52:1123-9.doi:10.1093/cid/cir179
    • (2011) Clin Infect Dis , vol.52 , pp. 1123-1129
    • Denning, D.W.1    Park, S.2    Lass-Florl, C.3    Fraczek, M.G.4    Kirwan, M.5    Gore, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.