High prevalence of triazole resistance in Aspergillus fumigatus, especially mediated by TR/L98H, in a French cohort of patients with cystic fibrosis

Journal of Antimicrobial Chemotherapy

Volumn 67, Issue 8, 2012, Pages 1870-1873

  Morio, Florent ^a,b   Aubin, Guillaume G ^b   Danner Boucher, Isabelle ^b   Haloun, Alain ^b   Sacchetto, Emilie ^b   Garcia Hermoso, Dea ^c,d   Bretagne, Stéphane ^c,d   Miegeville, Michel ^a,b   Le Pape, Patrice ^a,b  

^a UNIVERSITÉ DE NANTES   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c INSTITUT PASTEUR   (France)

^d CNRS   (France)

Author keywords

A. fumigatus; CFTR; Cyp51A mutations; Multi azole resistance

Indexed keywords

AGAR; BETA TUBULIN; CYP51A PROTEIN; FUNGAL PROTEIN; ITRACONAZOLE; POSACONAZOLE; UNCLASSIFIED DRUG; VORICONAZOLE;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; ASPERGILLUS FUMIGATUS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; CYSTIC FIBROSIS; FEMALE; FUNGAL GENE; FUNGUS GROWTH; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCHOOL CHILD;

ADOLESCENT; ADULT; ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; DRUG RESISTANCE, FUNGAL; FRANCE; HUMANS; ITRACONAZOLE; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PREVALENCE; PYRIMIDINES; RETROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA; TRIAZOLES; TUBULIN; YOUNG ADULT;

EID: 84864526497     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks160     Document Type: Article

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