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Volumn 7, Issue 23, 2015, Pages 2459-2469

Contribution of the toxic advanced glycation end-products-receptor axis in nonalcoholic steatohepatitis-related hepatocellular carcinoma

Author keywords

Advanced glycation end products; Hepatic stellate cells; Hepatocellular carcinoma; Nonalcoholic steatohepatitis; Receptor for advanced glycation end products; Toxic advanced glycation end products

Indexed keywords


EID: 84944043271     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v7.i23.2459     Document Type: Review
Times cited : (29)

References (111)
  • 1
    • 0037412432 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • [PMID: 12684589]
    • Yu AS, Keeffe EB. Management of hepatocellular carcinoma. Rev Gastroenterol Disord 2003; 3: 8-24 [PMID: 12684589]
    • (2003) Rev Gastroenterol Disord , vol.3 , pp. 8-24
    • Yu, A.S.1    Keeffe, E.B.2
  • 2
    • 7044229778 scopus 로고    scopus 로고
    • Primary liver cancer: worldwide incidence and trends
    • [PMID: 15508102]
    • Bosch FX, Ribes J, Díaz M, Cléries R. Primary liver cancer: worldwide incidence and trends. Gastroenterology 2004; 127: S5-S16 [PMID: 15508102 DOI: 10.1053/j.gastro.2004.09.011]
    • (2004) Gastroenterology , vol.127 , pp. S5-S16
    • Bosch, F.X.1    Ribes, J.2    Díaz, M.3    Cléries, R.4
  • 3
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • [PMID: 21351269]
    • Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-2917 [PMID: 21351269 DOI: 10.1002/ijc.25516]
    • (2010) Int J Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3    Forman, D.4    Mathers, C.5    Parkin, D.M.6
  • 4
  • 5
    • 14944385553 scopus 로고    scopus 로고
    • Global cancer statistics, 2002
    • [PMID: 15761078]
    • Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108 [PMID: 15761078 DOI: 10.3322/canjclin.55.2.74]
    • (2005) CA Cancer J Clin , vol.55 , pp. 74-108
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 6
    • 84901241878 scopus 로고    scopus 로고
    • Emerging trends in hepatocellular carcinoma: focus on diagnosis and therapeutics
    • [PMID: 24899827]
    • Flores A, Marrero JA. Emerging trends in hepatocellular carcinoma: focus on diagnosis and therapeutics. Clin Med Insights Oncol 2014; 8: 71-76 [PMID: 24899827 DOI: 10.4137/CMO. S9926]
    • (2014) Clin Med Insights Oncol , vol.8 , pp. 71-76
    • Flores, A.1    Marrero, J.A.2
  • 7
    • 84897654813 scopus 로고    scopus 로고
    • Hepatocarcinogenesis in non-alcoholic fatty liver disease in Japan
    • [PMID: 24251711]
    • Tokushige K, Hashimoto E, Kodama K. Hepatocarcinogenesis in non-alcoholic fatty liver disease in Japan. J Gastroenterol Hepatol 2013; 28 Suppl 4: 88-92 [PMID: 24251711 DOI: 10.1111/jgh.12239]
    • (2013) J Gastroenterol Hepatol , vol.28 , pp. 88-92
    • Tokushige, K.1    Hashimoto, E.2    Kodama, K.3
  • 8
    • 85027932655 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease, alcoholic liver disease, and chronic liver disease of unknown etiology: report of the nationwide survey
    • [PMID: 21748549]
    • Tokushige K, Hashimoto E, Horie Y, Taniai M, Higuchi S. Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease, alcoholic liver disease, and chronic liver disease of unknown etiology: report of the nationwide survey. J Gastroenterol 2011; 46: 1230-1237 [PMID: 21748549 DOI: 10.1007/s00535-011-0431-9]
    • (2011) J Gastroenterol , vol.46 , pp. 1230-1237
    • Tokushige, K.1    Hashimoto, E.2    Horie, Y.3    Taniai, M.4    Higuchi, S.5
  • 11
    • 0032828872 scopus 로고    scopus 로고
    • Advanced glycation end products: detection and reversal
    • [PMID: 10507023]
    • al-Abed Y, Kapurniotu A, Bucala R. Advanced glycation end products: detection and reversal. Methods Enzymol 1999; 309: 152-172 [PMID: 10507023 DOI: 10.1016/S0076-6879(99)09013-8]
    • (1999) Methods Enzymol , vol.309 , pp. 152-172
    • al-Abed, Y.1    Kapurniotu, A.2    Bucala, R.3
  • 12
    • 0036167208 scopus 로고    scopus 로고
    • Diabetes and advanced glycation endproducts
    • [PMID: 11905595]
    • Vlassara H, Palace MR. Diabetes and advanced glycation endproducts. J Intern Med 2002; 251: 87-101 [PMID: 11905595 DOI: 10.1046/j.1365-2796.2002.00932.x]
    • (2002) J Intern Med , vol.251 , pp. 87-101
    • Vlassara, H.1    Palace, M.R.2
  • 13
    • 0035412127 scopus 로고    scopus 로고
    • Alternative routes for the formation of immunochemically distinct advanced glycation end-products in vivo
    • [PMID: 11899079]
    • Takeuchi M, Makita Z. Alternative routes for the formation of immunochemically distinct advanced glycation end-products in vivo. Curr Mol Med 2001; 1: 305-315 [PMID: 11899079 DOI: 10.2174/1566524013363735]
    • (2001) Curr Mol Med , vol.1 , pp. 305-315
    • Takeuchi, M.1    Makita, Z.2
  • 14
    • 0028934990 scopus 로고
    • Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction
    • [PMID: 7730303]
    • Glomb MA, Monnier VM. Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction. J Biol Chem 1995; 270: 10017-10026 [PMID: 7730303 DOI: 10.1074/jbc.270.17.10017]
    • (1995) J Biol Chem , vol.270 , pp. 10017-10026
    • Glomb, M.A.1    Monnier, V.M.2
  • 15
    • 0033571012 scopus 로고    scopus 로고
    • Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
    • [PMID: 10548540]
    • Thornalley PJ, Langborg A, Minhas HS. Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose. Biochem J 1999; 344 Pt 1: 109-116 [PMID: 10548540]
    • (1999) Biochem J , vol.344 , pp. 109-116
    • Thornalley, P.J.1    Langborg, A.2    Minhas, H.S.3
  • 16
    • 3342891410 scopus 로고    scopus 로고
    • TAGE (toxic AGEs) hypothesis in various chronic diseases
    • [PMID: 15288366]
    • Takeuchi M, Yamagishi S. TAGE (toxic AGEs) hypothesis in various chronic diseases. Med Hypotheses 2004; 63: 449-452 [PMID: 15288366 DOI: 10.1016/j.mehy.2004.02.042]
    • (2004) Med Hypotheses , vol.63 , pp. 449-452
    • Takeuchi, M.1    Yamagishi, S.2
  • 17
    • 33646556661 scopus 로고    scopus 로고
    • TAGE (toxic AGEs) theory in diabetic complications
    • [PMID: 16712480]
    • Sato T, Iwaki M, Shimogaito N, Wu X, Yamagishi S, Takeuchi M. TAGE (toxic AGEs) theory in diabetic complications. Curr Mol Med 2006; 6: 351-358 [PMID: 16712480 DOI: 10.2174/156652406776894536]
    • (2006) Curr Mol Med , vol.6 , pp. 351-358
    • Sato, T.1    Iwaki, M.2    Shimogaito, N.3    Wu, X.4    Yamagishi, S.5    Takeuchi, M.6
  • 18
    • 44449097168 scopus 로고    scopus 로고
    • AGE-RAGE system and carcinogenesis
    • [PMID: 18473843]
    • Abe R, Yamagishi S. AGE-RAGE system and carcinogenesis. Curr Pharm Des 2008; 14: 940-945 [PMID: 18473843 DOI: 10.2174/138161208784139765]
    • (2008) Curr Pharm Des , vol.14 , pp. 940-945
    • Abe, R.1    Yamagishi, S.2
  • 19
    • 44449166649 scopus 로고    scopus 로고
    • Advanced glycation end products (AGEs) and their involvement in liver disease
    • [PMID: 18473847]
    • Hyogo H, Yamagishi S. Advanced glycation end products (AGEs) and their involvement in liver disease. Curr Pharm Des 2008; 14: 969-972 [PMID: 18473847 DOI: 10.2174/138161208784139701]
    • (2008) Curr Pharm Des , vol.14 , pp. 969-972
    • Hyogo, H.1    Yamagishi, S.2
  • 20
    • 44449179863 scopus 로고    scopus 로고
    • Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease
    • [PMID: 18473848]
    • Takeuchi M, Yamagishi S. Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease. Curr Pharm Des 2008; 14: 973-978 [PMID: 18473848 DOI: 10.2174/138161208784139693]
    • (2008) Curr Pharm Des , vol.14 , pp. 973-978
    • Takeuchi, M.1    Yamagishi, S.2
  • 21
    • 67649695176 scopus 로고    scopus 로고
    • Involvement of toxic AGEs (TAGE) in the pathogenesis of diabetic vascular complications and Alzheimer's disease
    • [PMID: 19387117]
    • Takeuchi M, Yamagishi S. Involvement of toxic AGEs (TAGE) in the pathogenesis of diabetic vascular complications and Alzheimer's disease. J Alzheimers Dis 2009; 16: 845-858 [PMID: 19387117 DOI: 10.3233/JAD-2009-0974]
    • (2009) J Alzheimers Dis , vol.16 , pp. 845-858
    • Takeuchi, M.1    Yamagishi, S.2
  • 22
    • 79954991400 scopus 로고    scopus 로고
    • Involvement of the toxic AGEs (TAGE)-RAGE system in the pathogenesis of diabetic vascular complications: a novel therapeutic strategy
    • [PMID: 20583971]
    • Takeuchi M, Takino J, Yamagishi S. Involvement of the toxic AGEs (TAGE)-RAGE system in the pathogenesis of diabetic vascular complications: a novel therapeutic strategy. Curr Drug Targets 2010; 11: 1468-1482 [PMID: 20583971 DOI: 10.2174/1389450111009011468]
    • (2010) Curr Drug Targets , vol.11 , pp. 1468-1482
    • Takeuchi, M.1    Takino, J.2    Yamagishi, S.3
  • 23
    • 84859343649 scopus 로고    scopus 로고
    • Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes
    • [PMID: 21440603]
    • Yamagishi S, Maeda S, Matsui T, Ueda S, Fukami K, Okuda S. Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes. Biochim Biophys Acta 2012; 1820: 663-671 [PMID: 21440603 DOI: 10.1016/j. bbagen.2011.03.014]
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 663-671
    • Yamagishi, S.1    Maeda, S.2    Matsui, T.3    Ueda, S.4    Fukami, K.5    Okuda, S.6
  • 24
    • 84987917076 scopus 로고    scopus 로고
    • Involvement of the TAGERAGE system in non-alcoholic steatohepatitis: Novel treatment strategies
    • [PMID: 25544875]
    • Takeuchi M, Takino J, Sakasai-Sakai A, Takata T, Ueda T, Tsutsumi M, Hyogo H, Yamagishi S. Involvement of the TAGERAGE system in non-alcoholic steatohepatitis: Novel treatment strategies. World J Hepatol 2014; 6: 880-893 [PMID: 25544875 DOI: 10.4254/wjh.v6.i12.880]
    • (2014) World J Hepatol , vol.6 , pp. 880-893
    • Takeuchi, M.1    Takino, J.2    Sakasai-Sakai, A.3    Takata, T.4    Ueda, T.5    Tsutsumi, M.6    Hyogo, H.7    Yamagishi, S.8
  • 26
    • 0034277471 scopus 로고    scopus 로고
    • Atherosclerosis and diabetes: the RAGE connection
    • [PMID: 11122775]
    • Schmidt AM, Stern D. Atherosclerosis and diabetes: the RAGE connection. Curr Atheroscler Rep 2000; 2: 430-436 [PMID: 11122775 DOI: 10.1007/s11883-000-0082-4]
    • (2000) Curr Atheroscler Rep , vol.2 , pp. 430-436
    • Schmidt, A.M.1    Stern, D.2
  • 27
    • 0000352972 scopus 로고    scopus 로고
    • Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: insights into the pathogenesis of macrovascular complications in diabetes
    • [PMID: 11931721]
    • Wendt T, Bucciarelli L, Qu W, Lu Y, Yan SF, Stern DM, Schmidt AM. Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: insights into the pathogenesis of macrovascular complications in diabetes. Curr Atheroscler Rep 2002; 4: 228-237 [PMID: 11931721 DOI: 10.1007/s11883-002-0024-4]
    • (2002) Curr Atheroscler Rep , vol.4 , pp. 228-237
    • Wendt, T.1    Bucciarelli, L.2    Qu, W.3    Lu, Y.4    Yan, S.F.5    Stern, D.M.6    Schmidt, A.M.7
  • 28
    • 0142029114 scopus 로고    scopus 로고
    • Novel inhibitors of advanced glycation endproducts
    • [PMID: 14568010]
    • Rahbar S, Figarola JL. Novel inhibitors of advanced glycation endproducts. Arch Biochem Biophys 2003; 419: 63-79 [PMID: 14568010 DOI: 10.1016/j.abb.2003.08.009]
    • (2003) Arch Biochem Biophys , vol.419 , pp. 63-79
    • Rahbar, S.1    Figarola, J.L.2
  • 29
    • 3042637228 scopus 로고    scopus 로고
    • Role of advanced glycation end products (AGEs) and their receptor (RAGE) in the pathogenesis of diabetic microangiopathy
    • [PMID: 15224502]
    • Yamagishi S, Takeuchi M, Inagaki Y, Nakamura K, Imaizumi T. Role of advanced glycation end products (AGEs) and their receptor (RAGE) in the pathogenesis of diabetic microangiopathy. Int J Clin Pharmacol Res 2003; 23: 129-134 [PMID: 15224502]
    • (2003) Int J Clin Pharmacol Res , vol.23 , pp. 129-134
    • Yamagishi, S.1    Takeuchi, M.2    Inagaki, Y.3    Nakamura, K.4    Imaizumi, T.5
  • 30
    • 21044443182 scopus 로고    scopus 로고
    • Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy
    • [PMID: 16022668]
    • Yamagishi S, Imaizumi T. Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy. Curr Pharm Des 2005; 11: 2279-2299 [PMID: 16022668 DOI: 10.2174/1381612054367300]
    • (2005) Curr Pharm Des , vol.11 , pp. 2279-2299
    • Yamagishi, S.1    Imaizumi, T.2
  • 31
    • 33645890286 scopus 로고    scopus 로고
    • Role of advanced glycation end products (AGEs) in thrombogenic abnormalities in diabetes
    • [PMID: 16472128]
    • Takenaka K, Yamagishi S, Matsui T, Nakamura K, Imaizumi T. Role of advanced glycation end products (AGEs) in thrombogenic abnormalities in diabetes. Curr Neurovasc Res 2006; 3: 73-77 [PMID: 16472128 DOI: 10.2174/156720206775541804]
    • (2006) Curr Neurovasc Res , vol.3 , pp. 73-77
    • Takenaka, K.1    Yamagishi, S.2    Matsui, T.3    Nakamura, K.4    Imaizumi, T.5
  • 33
    • 77955395009 scopus 로고    scopus 로고
    • Cancer malignancy is enhanced by glyceraldehyde-derived advanced glycation endproducts
    • [PMID: 20631911]
    • Takino J, Yamagishi S, Takeuchi M. Cancer malignancy is enhanced by glyceraldehyde-derived advanced glycation endproducts. J Oncol 2010; 2010: 739852 [PMID: 20631911 DOI: 10.1155/2010/739852]
    • (2010) J Oncol , vol.2010 , pp. 739852
    • Takino, J.1    Yamagishi, S.2    Takeuchi, M.3
  • 35
    • 84866155524 scopus 로고    scopus 로고
    • Glycer-AGEs-RAGE signaling enhances the angiogenic potential of hepatocellular carcinoma by upregulating VEGF expression
    • [PMID: 22553402]
    • Takino J, Yamagishi S, Takeuchi M. Glycer-AGEs-RAGE signaling enhances the angiogenic potential of hepatocellular carcinoma by upregulating VEGF expression. World J Gastroenterol 2012; 18: 1781-1788 [PMID: 22553402 DOI: 10.3748/wjg.v18.i15.1781]
    • (2012) World J Gastroenterol , vol.18 , pp. 1781-1788
    • Takino, J.1    Yamagishi, S.2    Takeuchi, M.3
  • 36
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • [PMID: 11961152]
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-1231 [PMID: 11961152 DOI: 10.1056/NEJMra011775]
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 37
    • 75149166672 scopus 로고    scopus 로고
    • Metabolic effects of fructose and the worldwide increase in obesity
    • [PMID: 20086073]
    • Tappy L, Lê KA. Metabolic effects of fructose and the worldwide increase in obesity. Physiol Rev 2010; 90: 23-46 [PMID: 20086073 DOI: 10.1152/physrev.00019.2009]
    • (2010) Physiol Rev , vol.90 , pp. 23-46
    • Tappy, L.1    Lê, K.A.2
  • 38
    • 78349283092 scopus 로고    scopus 로고
    • Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome
    • [PMID: 20823452]
    • Dekker MJ, Su Q, Baker C, Rutledge AC, Adeli K. Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome. Am J Physiol Endocrinol Metab 2010; 299: E685-E694 [PMID: 20823452 DOI: 10.1152/ajpendo.00283.2010]
    • (2010) Am J Physiol Endocrinol Metab , vol.299 , pp. E685-E694
    • Dekker, M.J.1    Su, Q.2    Baker, C.3    Rutledge, A.C.4    Adeli, K.5
  • 39
    • 84879090877 scopus 로고    scopus 로고
    • Dietary fructose in nonalcoholic fatty liver disease
    • [PMID: 23390127]
    • Vos MB, Lavine JE. Dietary fructose in nonalcoholic fatty liver disease. Hepatology 2013; 57: 2525-2531 [PMID: 23390127 DOI: 10.1002/hep.26299]
    • (2013) Hepatology , vol.57 , pp. 2525-2531
    • Vos, M.B.1    Lavine, J.E.2
  • 40
    • 84876522373 scopus 로고    scopus 로고
    • Current concepts and management approaches in nonalcoholic fatty liver disease
    • [PMID: 23576902]
    • Attar BM, Van Thiel DH. Current concepts and management approaches in nonalcoholic fatty liver disease. ScientificWorldJournal 2013; 2013: 481893 [PMID: 23576902 DOI: 10.1155/2013/481893]
    • (2013) ScientificWorldJournal , vol.2013 , pp. 481893
    • Attar, B.M.1    Van Thiel, D.H.2
  • 41
    • 84885920935 scopus 로고    scopus 로고
    • Nutritional management of insulin resistance in nonalcoholic fatty liver disease (NAFLD)
    • [PMID: 24152749]
    • Conlon BA, Beasley JM, Aebersold K, Jhangiani SS, Wylie-Rosett J. Nutritional management of insulin resistance in nonalcoholic fatty liver disease (NAFLD). Nutrients 2013; 5: 4093-4114 [PMID: 24152749 DOI: 10.3390/nu5104093]
    • (2013) Nutrients , vol.5 , pp. 4093-4114
    • Conlon, B.A.1    Beasley, J.M.2    Aebersold, K.3    Jhangiani, S.S.4    Wylie-Rosett, J.5
  • 42
    • 21344449292 scopus 로고    scopus 로고
    • Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study
    • [PMID: 15895401]
    • Bedogni G, Miglioli L, Masutti F, Tiribelli C, Marchesini G, Bellentani S. Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology 2005; 42: 44-52 [PMID: 15895401 DOI: 10.1002/hep.20734]
    • (2005) Hepatology , vol.42 , pp. 44-52
    • Bedogni, G.1    Miglioli, L.2    Masutti, F.3    Tiribelli, C.4    Marchesini, G.5    Bellentani, S.6
  • 43
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • [PMID: 7382552]
    • Ludwig J, Viggiano TR, McGill DB, Oh BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980; 55: 434-438 [PMID: 7382552]
    • (1980) Mayo Clin Proc , vol.55 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3    Oh, B.J.4
  • 47
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity
    • [PMID: 10348825]
    • Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999; 116: 1413-1419 [PMID: 10348825 DOI: 10.1016/S0016-5085(99)70506-8]
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3    Boparai, N.4    Liu, Y.C.5    McCullough, A.J.6
  • 49
    • 58849132440 scopus 로고    scopus 로고
    • Clinical features and outcomes of cirrhosis due to nonalcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C
    • [PMID: 19032450]
    • Yatsuji S, Hashimoto E, Tobari M, Taniai M, Tokushige K, Shiratori K. Clinical features and outcomes of cirrhosis due to nonalcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C. J Gastroenterol Hepatol 2009; 24: 248-254 [PMID: 19032450 DOI: 10.1111/j.1440-1746.2008.05640.x]
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 248-254
    • Yatsuji, S.1    Hashimoto, E.2    Tobari, M.3    Taniai, M.4    Tokushige, K.5    Shiratori, K.6
  • 50
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection
    • [PMID: 20432259]
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology 2010; 51: 1820-1832 [PMID: 20432259 DOI: 10.1002/hep.23594]
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 51
    • 77950803622 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis-associated hepatocellular carcinoma: our case series and literature review
    • [PMID: 20333782]
    • Takuma Y, Nouso K. Nonalcoholic steatohepatitis-associated hepatocellular carcinoma: our case series and literature review. World J Gastroenterol 2010; 16: 1436-1441 [PMID: 20333782 DOI: 10.3748/wjg.v16.i12.1436]
    • (2010) World J Gastroenterol , vol.16 , pp. 1436-1441
    • Takuma, Y.1    Nouso, K.2
  • 52
    • 79953185045 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis
    • [PMID: 21128245]
    • Ertle J, Dechêne A, Sowa JP, Penndorf V, Herzer K, Kaiser G, Schlaak JF, Gerken G, Syn WK, Canbay A. Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis. Int J Cancer 2011; 128: 2436-2443 [PMID: 21128245 DOI: 10.1002/ijc.25797]
    • (2011) Int J Cancer , vol.128 , pp. 2436-2443
    • Ertle, J.1    Dechêne, A.2    Sowa, J.P.3    Penndorf, V.4    Herzer, K.5    Kaiser, G.6    Schlaak, J.F.7    Gerken, G.8    Syn, W.K.9    Canbay, A.10
  • 53
    • 0033019013 scopus 로고    scopus 로고
    • Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease
    • [PMID: 10051466]
    • Caldwell SH, Oelsner DH, Iezzoni JC, Hespenheide EE, Battle EH, Driscoll CJ. Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 1999; 29: 664-669 [PMID: 10051466 DOI: 10.1002/hep.510290347]
    • (1999) Hepatology , vol.29 , pp. 664-669
    • Caldwell, S.H.1    Oelsner, D.H.2    Iezzoni, J.C.3    Hespenheide, E.E.4    Battle, E.H.5    Driscoll, C.J.6
  • 54
    • 0034843450 scopus 로고    scopus 로고
    • Cryptogenic cirrhosis and posttransplantation nonalcoholic fatty liver disease
    • [PMID: 11552214]
    • Ong J, Younossi ZM, Reddy V, Price LL, Gramlich T, Mayes J, Boparai N. Cryptogenic cirrhosis and posttransplantation nonalcoholic fatty liver disease. Liver Transpl 2001; 7: 797-801 [PMID: 11552214 DOI: 10.1053/jlts.2001.24644]
    • (2001) Liver Transpl , vol.7 , pp. 797-801
    • Ong, J.1    Younossi, Z.M.2    Reddy, V.3    Price, L.L.4    Gramlich, T.5    Mayes, J.6    Boparai, N.7
  • 55
    • 0033797838 scopus 로고    scopus 로고
    • Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study
    • [PMID: 11003611]
    • Poonawala A, Nair SP, Thuluvath PJ. Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study. Hepatology 2000; 32: 689-692 [PMID: 11003611 DOI: 10.1053/jhep.2000.17894]
    • (2000) Hepatology , vol.32 , pp. 689-692
    • Poonawala, A.1    Nair, S.P.2    Thuluvath, P.J.3
  • 56
    • 0036894480 scopus 로고    scopus 로고
    • NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States
    • [PMID: 12447858]
    • Marrero JA, Fontana RJ, Su GL, Conjeevaram HS, Emick DM, Lok AS. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology 2002; 36: 1349-1354 [PMID: 12447858 DOI: 10.1002/hep.1840360609]
    • (2002) Hepatology , vol.36 , pp. 1349-1354
    • Marrero, J.A.1    Fontana, R.J.2    Su, G.L.3    Conjeevaram, H.S.4    Emick, D.M.5    Lok, A.S.6
  • 57
    • 0030176306 scopus 로고    scopus 로고
    • Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy
    • [PMID: 8853285]
    • Thornalley PJ. Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy. Gen Pharmacol 1996; 27: 565-573 [PMID: 8853285 DOI: 10.1016/0306-3623(95)02054-3]
    • (1996) Gen Pharmacol , vol.27 , pp. 565-573
    • Thornalley, P.J.1
  • 58
    • 0032810308 scopus 로고    scopus 로고
    • Detection of noncarboxymethyllysine and carboxymethyllysine advanced glycation end products (AGE) in serum of diabetic patients
    • [PMID: 10415164]
    • Takeuchi M, Makita Z, Yanagisawa K, Kameda Y, Koike T. Detection of noncarboxymethyllysine and carboxymethyllysine advanced glycation end products (AGE) in serum of diabetic patients. Mol Med 1999; 5: 393-405 [PMID: 10415164]
    • (1999) Mol Med , vol.5 , pp. 393-405
    • Takeuchi, M.1    Makita, Z.2    Yanagisawa, K.3    Kameda, Y.4    Koike, T.5
  • 59
    • 0034136370 scopus 로고    scopus 로고
    • Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo
    • [PMID: 10859028]
    • Takeuchi M, Makita Z, Bucala R, Suzuki T, Koike T, Kameda Y. Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo. Mol Med 2000; 6: 114-125 [PMID: 10859028]
    • (2000) Mol Med , vol.6 , pp. 114-125
    • Takeuchi, M.1    Makita, Z.2    Bucala, R.3    Suzuki, T.4    Koike, T.5    Kameda, Y.6
  • 61
    • 77954164767 scopus 로고    scopus 로고
    • Immunological detection of fructose-derived advanced glycation end-products
    • [PMID: 20212455]
    • Takeuchi M, Iwaki M, Takino J, Shirai H, Kawakami M, Bucala R, Yamagishi S. Immunological detection of fructose-derived advanced glycation end-products. Lab Invest 2010; 90: 1117-1127 [PMID: 20212455 DOI: 10.1038/labinvest.2010.62]
    • (2010) Lab Invest , vol.90 , pp. 1117-1127
    • Takeuchi, M.1    Iwaki, M.2    Takino, J.3    Shirai, H.4    Kawakami, M.5    Bucala, R.6    Yamagishi, S.7
  • 62
    • 3342948649 scopus 로고    scopus 로고
    • Alternative routes for the formation of glyceraldehyde-derived AGEs (TAGE) in vivo
    • [PMID: 15288367]
    • Takeuchi M, Yamagishi S. Alternative routes for the formation of glyceraldehyde-derived AGEs (TAGE) in vivo. Med Hypotheses 2004; 63: 453-455 [PMID: 15288367 DOI: 10.1016/j. mehy.2004.03.005]
    • (2004) Med Hypotheses , vol.63 , pp. 453-455
    • Takeuchi, M.1    Yamagishi, S.2
  • 63
    • 0026482265 scopus 로고
    • Advanced glycosylation: chemistry, biology, and implications for diabetes and aging
    • [PMID: 1540533]
    • Bucala R, Cerami A. Advanced glycosylation: chemistry, biology, and implications for diabetes and aging. Adv Pharmacol 1992; 23: 1-34 [PMID: 1540533 DOI: 10.1016/S1054-3589(08)60961-8]
    • (1992) Adv Pharmacol , vol.23 , pp. 1-34
    • Bucala, R.1    Cerami, A.2
  • 64
    • 0028272883 scopus 로고
    • Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging
    • [PMID: 8139257]
    • Vlassara H, Bucala R, Striker L. Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging. Lab Invest 1994; 70: 138-151 [PMID: 8139257]
    • (1994) Lab Invest , vol.70 , pp. 138-151
    • Vlassara, H.1    Bucala, R.2    Striker, L.3
  • 65
    • 0028908348 scopus 로고
    • Advanced protein glycosylation in diabetes and aging
    • [PMID: 7598459]
    • Brownlee M. Advanced protein glycosylation in diabetes and aging. Annu Rev Med 1995; 46: 223-234 [PMID: 7598459 DOI: 10.1146/annurev.med.46.1.223]
    • (1995) Annu Rev Med , vol.46 , pp. 223-234
    • Brownlee, M.1
  • 66
    • 0023950461 scopus 로고
    • Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
    • [PMID: 3283558]
    • Brownlee M, Cerami A, Vlassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N Engl J Med 1988; 318: 1315-1321 [PMID: 3283558 DOI: 10.1056/NEJM198805193182007]
    • (1988) N Engl J Med , vol.318 , pp. 1315-1321
    • Brownlee, M.1    Cerami, A.2    Vlassara, H.3
  • 67
    • 0019475899 scopus 로고
    • Nonenzymatic browning in vivo: possible process for aging of long-lived proteins
    • [PMID: 6779377]
    • Monnier VM, Cerami A. Nonenzymatic browning in vivo: possible process for aging of long-lived proteins. Science 1981; 211: 491-493 [PMID: 6779377 DOI: 10.1126/science.6779377]
    • (1981) Science , vol.211 , pp. 491-493
    • Monnier, V.M.1    Cerami, A.2
  • 68
    • 0029923574 scopus 로고    scopus 로고
    • The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions
    • [PMID: 8626637]
    • Fu MX, Requena JR, Jenkins AJ, Lyons TJ, Baynes JW, Thorpe SR. The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions. J Biol Chem 1996; 271: 9982-9986 [PMID: 8626637 DOI: 10.1074/jbc.271.17.9982]
    • (1996) J Biol Chem , vol.271 , pp. 9982-9986
    • Fu, M.X.1    Requena, J.R.2    Jenkins, A.J.3    Lyons, T.J.4    Baynes, J.W.5    Thorpe, S.R.6
  • 69
    • 0036126560 scopus 로고    scopus 로고
    • Markedly elevated levels of plasma advanced glycation end products in patients with liver cirrhosis - amelioration by liver transplantation
    • [PMID: 11804666]
    • Sebeková K, Kupcová V, Schinzel R, Heidland A. Markedly elevated levels of plasma advanced glycation end products in patients with liver cirrhosis - amelioration by liver transplantation. J Hepatol 2002; 36: 66-71 [PMID: 11804666]
    • (2002) J Hepatol , vol.36 , pp. 66-71
    • Sebeková, K.1    Kupcová, V.2    Schinzel, R.3    Heidland, A.4
  • 70
    • 29344443061 scopus 로고    scopus 로고
    • Elevation of Nepsilon-(carboxymethyl) lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis
    • [PMID: 16321365]
    • Yagmur E, Tacke F, Weiss C, Lahme B, Manns MP, Kiefer P, Trautwein C, Gressner AM. Elevation of Nepsilon-(carboxymethyl) lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis. Clin Biochem 2006; 39: 39-45 [PMID: 16321365 DOI: 10.1016/j.clinbiochem.2005.07.016]
    • (2006) Clin Biochem , vol.39 , pp. 39-45
    • Yagmur, E.1    Tacke, F.2    Weiss, C.3    Lahme, B.4    Manns, M.P.5    Kiefer, P.6    Trautwein, C.7    Gressner, A.M.8
  • 72
    • 77955664397 scopus 로고    scopus 로고
    • Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH
    • [PMID: 20112031]
    • Kimura Y, Hyogo H, Yamagishi S, Takeuchi M, Ishitobi T, Nabeshima Y, Arihiro K, Chayama K. Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH. J Gastroenterol 2010; 45: 750-757 [PMID: 20112031 DOI: 10.1007/s00535-010-0203-y]
    • (2010) J Gastroenterol , vol.45 , pp. 750-757
    • Kimura, Y.1    Hyogo, H.2    Yamagishi, S.3    Takeuchi, M.4    Ishitobi, T.5    Nabeshima, Y.6    Arihiro, K.7    Chayama, K.8
  • 73
    • 84954318925 scopus 로고    scopus 로고
    • Elevation of Serum Levels of Advanced Glycation End Products in Patients With Non-B or Non-C Hepatocellular Carcinoma
    • Epub ahead of print [PMID: 25252033]
    • Kan H, Yamagishi SI, Ojima A, Fukami K, Ueda S, Takeuchi M, Hyogo H, Aikata H, Chayama K. Elevation of Serum Levels of Advanced Glycation End Products in Patients With Non-B or Non-C Hepatocellular Carcinoma. J Clin Lab Anal 2014; Epub ahead of print [PMID: 25252033 DOI: 10.1002/jcla.21797]
    • (2014) J Clin Lab Anal
    • Kan, H.1    Yamagishi, S.I.2    Ojima, A.3    Fukami, K.4    Ueda, S.5    Takeuchi, M.6    Hyogo, H.7    Aikata, H.8    Chayama, K.9
  • 75
    • 84925710959 scopus 로고    scopus 로고
    • Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH
    • [PMID: 25697114]
    • Takeuchi M, Sakasai-Sakai A, Takata T, Ueda T, Takino J, Tsutsumi M, Hyogo H, Yamagishi S. Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH. Med Hypotheses 2015; 84: 490-493 [PMID: 25697114 DOI: 10.1016/j.mehy.2015.02.002]
    • (2015) Med Hypotheses , vol.84 , pp. 490-493
    • Takeuchi, M.1    Sakasai-Sakai, A.2    Takata, T.3    Ueda, T.4    Takino, J.5    Tsutsumi, M.6    Hyogo, H.7    Yamagishi, S.8
  • 76
    • 0034795140 scopus 로고    scopus 로고
    • The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
    • [PMID: 11581294]
    • Schmidt AM, Yan SD, Yan SF, Stern DM. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 2001; 108: 949-955 [PMID: 11581294 DOI: 10.1172/JCI14002]
    • (2001) J Clin Invest , vol.108 , pp. 949-955
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 77
    • 0036156244 scopus 로고    scopus 로고
    • Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer
    • [PMID: 11793367]
    • Kuniyasu H, Oue N, Wakikawa A, Shigeishi H, Matsutani N, Kuraoka K, Ito R, Yokozaki H, Yasui W. Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer. J Pathol 2002; 196: 163-170 [PMID: 11793367 DOI: 10.1002/path.1031]
    • (2002) J Pathol , vol.196 , pp. 163-170
    • Kuniyasu, H.1    Oue, N.2    Wakikawa, A.3    Shigeishi, H.4    Matsutani, N.5    Kuraoka, K.6    Ito, R.7    Yokozaki, H.8    Yasui, W.9
  • 79
    • 84861536618 scopus 로고    scopus 로고
    • High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases
    • [PMID: 22234969]
    • Yan W, Chang Y, Liang X, Cardinal JS, Huang H, Thorne SH, Monga SP, Geller DA, Lotze MT, Tsung A. High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases. Hepatology 2012; 55: 1863-1875 [PMID: 22234969 DOI: 10.1002/hep.25572]
    • (2012) Hepatology , vol.55 , pp. 1863-1875
    • Yan, W.1    Chang, Y.2    Liang, X.3    Cardinal, J.S.4    Huang, H.5    Thorne, S.H.6    Monga, S.P.7    Geller, D.A.8    Lotze, M.T.9    Tsung, A.10
  • 80
    • 84898910879 scopus 로고    scopus 로고
    • The role of HMGB1-RAGE axis in migration and invasion of hepatocellular carcinoma cell lines
    • [PMID: 24510323]
    • Chen RC, Yi PP, Zhou RR, Xiao MF, Huang ZB, Tang DL, Huang Y, Fan XG. The role of HMGB1-RAGE axis in migration and invasion of hepatocellular carcinoma cell lines. Mol Cell Biochem 2014; 390: 271-280 [PMID: 24510323 DOI: 10.1007/s11010-014-1978-6]
    • (2014) Mol Cell Biochem , vol.390 , pp. 271-280
    • Chen, R.C.1    Yi, P.P.2    Zhou, R.R.3    Xiao, M.F.4    Huang, Z.B.5    Tang, D.L.6    Huang, Y.7    Fan, X.G.8
  • 81
    • 39149118886 scopus 로고    scopus 로고
    • A novel function of the receptor for advanced glycation end-products (RAGE) in association with tumorigenesis and tumor differentiation of HCC
    • [PMID: 18080716]
    • Hiwatashi K, Ueno S, Abeyama K, Kubo F, Sakoda M, Maruyama I, Hamanoue M, Natsugoe S, Aikou T. A novel function of the receptor for advanced glycation end-products (RAGE) in association with tumorigenesis and tumor differentiation of HCC. Ann Surg Oncol 2008; 15: 923-933 [PMID: 18080716 DOI: 10.1245/s10434-007-9698-8]
    • (2008) Ann Surg Oncol , vol.15 , pp. 923-933
    • Hiwatashi, K.1    Ueno, S.2    Abeyama, K.3    Kubo, F.4    Sakoda, M.5    Maruyama, I.6    Hamanoue, M.7    Natsugoe, S.8    Aikou, T.9
  • 82
    • 0034768777 scopus 로고    scopus 로고
    • Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts
    • [PMID: 11679965]
    • Fehrenbach H, Weiskirchen R, Kasper M, Gressner AM. Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts. Hepatology 2001; 34: 943-952 [PMID: 11679965 DOI: 10.1053/jhep.2001.28788]
    • (2001) Hepatology , vol.34 , pp. 943-952
    • Fehrenbach, H.1    Weiskirchen, R.2    Kasper, M.3    Gressner, A.M.4
  • 83
    • 10744229479 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice
    • [PMID: 14767995]
    • Zeng S, Feirt N, Goldstein M, Guarrera J, Ippagunta N, Ekong U, Dun H, Lu Y, Qu W, Schmidt AM, Emond JC. Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice. Hepatology 2004; 39: 422-432 [PMID: 14767995]
    • (2004) Hepatology , vol.39 , pp. 422-432
    • Zeng, S.1    Feirt, N.2    Goldstein, M.3    Guarrera, J.4    Ippagunta, N.5    Ekong, U.6    Dun, H.7    Lu, Y.8    Qu, W.9    Schmidt, A.M.10    Emond, J.C.11
  • 86
    • 84867771965 scopus 로고    scopus 로고
    • Metabolic activation and inflammation reactions involved in carbamazepine-induced liver injury
    • [PMID: 22790970]
    • Higuchi S, Yano A, Takai S, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. Metabolic activation and inflammation reactions involved in carbamazepine-induced liver injury. Toxicol Sci 2012; 130: 4-16 [PMID: 22790970 DOI: 10.1093/toxsci/kfs222]
    • (2012) Toxicol Sci , vol.130 , pp. 4-16
    • Higuchi, S.1    Yano, A.2    Takai, S.3    Tsuneyama, K.4    Fukami, T.5    Nakajima, M.6    Yokoi, T.7
  • 88
    • 84879372858 scopus 로고    scopus 로고
    • Losartan protects liver against ischaemia/reperfusion injury through PPAR-γ activation and receptor for advanced glycation end-products down-regulation
    • [PMID: 23647130]
    • Koh EJ, Yoon SJ, Lee SM. Losartan protects liver against ischaemia/reperfusion injury through PPAR-γ activation and receptor for advanced glycation end-products down-regulation. Br J Pharmacol 2013; 169: 1404-1416 [PMID: 23647130 DOI: 10.1111/bph.12229]
    • (2013) Br J Pharmacol , vol.169 , pp. 1404-1416
    • Koh, E.J.1    Yoon, S.J.2    Lee, S.M.3
  • 89
    • 84880135909 scopus 로고    scopus 로고
    • RAGE blockade and hepatic microcirculation in experimental endotoxaemic liver failure
    • [PMID: 23804133]
    • Kuhla A, Norden J, Abshagen K, Menger MD, Vollmar B. RAGE blockade and hepatic microcirculation in experimental endotoxaemic liver failure. Br J Surg 2013; 100: 1229-1239 [PMID: 23804133 DOI: 10.1002/bjs.9188]
    • (2013) Br J Surg , vol.100 , pp. 1229-1239
    • Kuhla, A.1    Norden, J.2    Abshagen, K.3    Menger, M.D.4    Vollmar, B.5
  • 90
    • 84912114084 scopus 로고    scopus 로고
    • Prognostic significance of receptor for advanced glycation end products expression in hepatocellular carcinoma after hepatectomy
    • [PMID: 25043528]
    • Ito R, Ishii Y, Wakiyama S, Shiba H, Fujioka S, Misawa T, Ishida Y, Hano H, Yanaga K. Prognostic significance of receptor for advanced glycation end products expression in hepatocellular carcinoma after hepatectomy. J Surg Res 2014; 192: 503-508 [PMID: 25043528 DOI: 10.1016/j.jss.2014.06.028]
    • (2014) J Surg Res , vol.192 , pp. 503-508
    • Ito, R.1    Ishii, Y.2    Wakiyama, S.3    Shiba, H.4    Fujioka, S.5    Misawa, T.6    Ishida, Y.7    Hano, H.8    Yanaga, K.9
  • 91
    • 84944576851 scopus 로고    scopus 로고
    • Pioglitazone, a PPAR? agonist, inhibits growth and invasion of human hepatocellular carcinoma via blockade of the rage signaling
    • Epub ahead of print [PMID: 25307746]
    • Yang Y, Zhao LH, Huang B, Wang RY, Yuan SX, Tao QF, Xu Y, Sun HY, Lin C, Zhou WP. Pioglitazone, a PPAR? agonist, inhibits growth and invasion of human hepatocellular carcinoma via blockade of the rage signaling. Mol Carcinog 2014; Epub ahead of print [PMID: 25307746 DOI: 10.1002/mc.22231]
    • (2014) Mol Carcinog
    • Yang, Y.1    Zhao, L.H.2    Huang, B.3    Wang, R.Y.4    Yuan, S.X.5    Tao, Q.F.6    Xu, Y.7    Sun, H.Y.8    Lin, C.9    Zhou, W.P.10
  • 92
    • 33750913676 scopus 로고    scopus 로고
    • Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation
    • [PMID: 17004092]
    • Yoshida T, Yamagishi S, Nakamura K, Matsui T, Imaizumi T, Takeuchi M, Koga H, Ueno T, Sata M. Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation. Diabetologia 2006; 49: 3094-3099 [PMID: 17004092 DOI: 10.1007/s00125-006-0437-7]
    • (2006) Diabetologia , vol.49 , pp. 3094-3099
    • Yoshida, T.1    Yamagishi, S.2    Nakamura, K.3    Matsui, T.4    Imaizumi, T.5    Takeuchi, M.6    Koga, H.7    Ueno, T.8    Sata, M.9
  • 93
    • 0037444761 scopus 로고    scopus 로고
    • Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetesinduced vascular injury
    • [PMID: 12495433]
    • Yonekura H, Yamamoto Y, Sakurai S, Petrova RG, Abedin MJ, Li H, Yasui K, Takeuchi M, Makita Z, Takasawa S, Okamoto H, Watanabe T, Yamamoto H. Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetesinduced vascular injury. Biochem J 2003; 370: 1097-1109 [PMID: 12495433 DOI: 10.1042/BJ20021371]
    • (2003) Biochem J , vol.370 , pp. 1097-1109
    • Yonekura, H.1    Yamamoto, Y.2    Sakurai, S.3    Petrova, R.G.4    Abedin, M.J.5    Li, H.6    Yasui, K.7    Takeuchi, M.8    Makita, Z.9    Takasawa, S.10    Okamoto, H.11    Watanabe, T.12    Yamamoto, H.13
  • 94
    • 33745741894 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation end products: from disease marker to potential therapeutic target
    • [PMID: 16842191]
    • Geroldi D, Falcone C, Emanuele E. Soluble receptor for advanced glycation end products: from disease marker to potential therapeutic target. Curr Med Chem 2006; 13: 1971-1978 [PMID: 16842191 DOI: 10.2174/092986706777585013]
    • (2006) Curr Med Chem , vol.13 , pp. 1971-1978
    • Geroldi, D.1    Falcone, C.2    Emanuele, E.3
  • 95
    • 67349263467 scopus 로고    scopus 로고
    • Decreased plasma levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with nonalcoholic fatty liver disease
    • [PMID: 19217891]
    • Yilmaz Y, Ulukaya E, Gul OO, Arabul M, Gul CB, Atug O, Oral AY, Aker S, Dolar E. Decreased plasma levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with nonalcoholic fatty liver disease. Clin Biochem 2009; 42: 802-807 [PMID: 19217891 DOI: 10.1016/j.clinbiochem.2009.02.003]
    • (2009) Clin Biochem , vol.42 , pp. 802-807
    • Yilmaz, Y.1    Ulukaya, E.2    Gul, O.O.3    Arabul, M.4    Gul, C.B.5    Atug, O.6    Oral, A.Y.7    Aker, S.8    Dolar, E.9
  • 96
    • 85027938747 scopus 로고    scopus 로고
    • Predictive value of immunogenic cell death biomarkers HMGB1, sRAGE, and DNase in liver cancer patients receiving transarterial chemoembolization therapy
    • [PMID: 22965881]
    • Kohles N, Nagel D, Jüngst D, Stieber P, Holdenrieder S. Predictive value of immunogenic cell death biomarkers HMGB1, sRAGE, and DNase in liver cancer patients receiving transarterial chemoembolization therapy. Tumour Biol 2012; 33: 2401-2409 [PMID: 22965881 DOI: 10.1007/s13277-012-0504-2]
    • (2012) Tumour Biol , vol.33 , pp. 2401-2409
    • Kohles, N.1    Nagel, D.2    Jüngst, D.3    Stieber, P.4    Holdenrieder, S.5
  • 97
    • 38149001527 scopus 로고    scopus 로고
    • Serum levels of soluble form of receptor for advanced glycation end products (sRAGE) are correlated with AGEs in both diabetic and non-diabetic subjects
    • [PMID: 18188534]
    • Nakamura K, Yamagishi SI, Matsui T, Adachi H, Takeuchi M, Imaizumi T. Serum levels of soluble form of receptor for advanced glycation end products (sRAGE) are correlated with AGEs in both diabetic and non-diabetic subjects. Clin Exp Med 2007; 7: 188-190 [PMID: 18188534 DOI: 10.1007/s10238-007-0146-7]
    • (2007) Clin Exp Med , vol.7 , pp. 188-190
    • Nakamura, K.1    Yamagishi, S.I.2    Matsui, T.3    Adachi, H.4    Takeuchi, M.5    Imaizumi, T.6
  • 98
    • 33747039218 scopus 로고    scopus 로고
    • Positive association between serum levels of advanced glycation end products and the soluble form of receptor for advanced glycation end products in nondiabetic subjects
    • [PMID: 16919543]
    • Yamagishi S, Adachi H, Nakamura K, Matsui T, Jinnouchi Y, Takenaka K, Takeuchi M, Enomoto M, Furuki K, Hino A, Shigeto Y, Imaizumi T. Positive association between serum levels of advanced glycation end products and the soluble form of receptor for advanced glycation end products in nondiabetic subjects. Metabolism 2006; 55: 1227-1231 [PMID: 16919543 DOI: 10.1016/j.metabol.2006.05.007]
    • (2006) Metabolism , vol.55 , pp. 1227-1231
    • Yamagishi, S.1    Adachi, H.2    Nakamura, K.3    Matsui, T.4    Jinnouchi, Y.5    Takenaka, K.6    Takeuchi, M.7    Enomoto, M.8    Furuki, K.9    Hino, A.10    Shigeto, Y.11    Imaizumi, T.12
  • 99
    • 34249305184 scopus 로고    scopus 로고
    • Serum levels of soluble form of receptor for advanced glycation end products (sRAGE) may reflect tissue RAGE expression in diabetes
    • author reply e33-e34 [PMID: 17522392]
    • Yamagishi S, Imaizumi T. Serum levels of soluble form of receptor for advanced glycation end products (sRAGE) may reflect tissue RAGE expression in diabetes. Arterioscler Thromb Vasc Biol 2007; 27: e32; author reply e33-e34 [PMID: 17522392 DOI: 10.1161/ATVBAHA.107.139923]
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. e32
    • Yamagishi, S.1    Imaizumi, T.2
  • 100
    • 33646172955 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) inhibits advanced glycation end product (AGE)-induced C-reactive protein expression in hepatoma cells by suppressing Rac-1 activation
    • [PMID: 16674952]
    • Yoshida T, Yamagishi S, Nakamura K, Matsui T, Imaizumi T, Takeuchi M, Ueno T, Sata M. Pigment epithelium-derived factor (PEDF) inhibits advanced glycation end product (AGE)-induced C-reactive protein expression in hepatoma cells by suppressing Rac-1 activation. FEBS Lett 2006; 580: 2788-2796 [PMID: 16674952 DOI: 10.1016/j.febset.2006.04.050]
    • (2006) FEBS Lett , vol.580 , pp. 2788-2796
    • Yoshida, T.1    Yamagishi, S.2    Nakamura, K.3    Matsui, T.4    Imaizumi, T.5    Takeuchi, M.6    Ueno, T.7    Sata, M.8
  • 101
    • 84902015226 scopus 로고    scopus 로고
    • The addition of C-reactive protein to validated staging systems improves their prognostic ability in patients with hepatocellular carcinoma
    • [PMID: 24924697]
    • Kinoshita A, Onoda H, Imai N, Iwaku A, Oishi M, Tanaka K, Fushiya N, Koike K, Nishino H, Matsushima M, Tajiri H. The addition of C-reactive protein to validated staging systems improves their prognostic ability in patients with hepatocellular carcinoma. Oncology 2014; 86: 308-317 [PMID: 24924697 DOI: 10.1159/000360704]
    • (2014) Oncology , vol.86 , pp. 308-317
    • Kinoshita, A.1    Onoda, H.2    Imai, N.3    Iwaku, A.4    Oishi, M.5    Tanaka, K.6    Fushiya, N.7    Koike, K.8    Nishino, H.9    Matsushima, M.10    Tajiri, H.11
  • 102
    • 84876723146 scopus 로고    scopus 로고
    • C-reactive protein may be a prognostic factor in hepatocellular carcinoma with malignant portal vein invasion
    • [PMID: 23618082]
    • Kim JM, Kwon CH, Joh JW, Ko JS, Park JB, Lee JH, Kim SJ, Paik SW, Park CK. C-reactive protein may be a prognostic factor in hepatocellular carcinoma with malignant portal vein invasion. World J Surg Oncol 2013; 11: 92 [PMID: 23618082 DOI: 10.1186/1477-7819-11-92]
    • (2013) World J Surg Oncol , vol.11 , pp. 92
    • Kim, J.M.1    Kwon, C.H.2    Joh, J.W.3    Ko, J.S.4    Park, J.B.5    Lee, J.H.6    Kim, S.J.7    Paik, S.W.8    Park, C.K.9
  • 103
    • 43249111258 scopus 로고    scopus 로고
    • Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells
    • [PMID: 18458846]
    • Iwamoto K, Kanno K, Hyogo H, Yamagishi S, Takeuchi M, Tazuma S, Chayama K. Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells. J Gastroenterol 2008; 43: 298-304 [PMID: 18458846 DOI: 10.1007/s00535-007-2152-7]
    • (2008) J Gastroenterol , vol.43 , pp. 298-304
    • Iwamoto, K.1    Kanno, K.2    Hyogo, H.3    Yamagishi, S.4    Takeuchi, M.5    Tazuma, S.6    Chayama, K.7
  • 104
    • 35948964347 scopus 로고    scopus 로고
    • Hepatic stellate cells and liver fibrosis
    • [PMID: 17979495]
    • Moreira RK. Hepatic stellate cells and liver fibrosis. Arch Pathol Lab Med 2007; 131: 1728-1734 [PMID: 17979495]
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 1728-1734
    • Moreira, R.K.1
  • 105
    • 84902547850 scopus 로고    scopus 로고
    • Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever
    • [PMID: 24397349]
    • Carloni V, Luong TV, Rombouts K. Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever. Liver Int 2014; 34: 834-843 [PMID: 24397349 DOI: 10.1111/liv.12465]
    • (2014) Liver Int , vol.34 , pp. 834-843
    • Carloni, V.1    Luong, T.V.2    Rombouts, K.3
  • 106
    • 84901203792 scopus 로고    scopus 로고
    • Stellate cells and the development of liver cancer: therapeutic potential of targeting the stroma
    • [PMID: 24530649]
    • Coulouarn C, Clément B. Stellate cells and the development of liver cancer: therapeutic potential of targeting the stroma. J Hepatol 2014; 60: 1306-1309 [PMID: 24530649 DOI: 10.1016/j.jhep.2014.02.003]
    • (2014) J Hepatol , vol.60 , pp. 1306-1309
    • Coulouarn, C.1    Clément, B.2
  • 108
    • 84937540527 scopus 로고    scopus 로고
    • Hepatic stellate cells secretes type I collagen to trigger epithelial mesenchymal transition of hepatoma cells
    • [PMID: 25520865]
    • Yang MC, Wang CJ, Liao PC, Yen CJ, Shan YS. Hepatic stellate cells secretes type I collagen to trigger epithelial mesenchymal transition of hepatoma cells. Am J Cancer Res 2014; 4: 751-763 [PMID: 25520865]
    • (2014) Am J Cancer Res , vol.4 , pp. 751-763
    • Yang, M.C.1    Wang, C.J.2    Liao, P.C.3    Yen, C.J.4    Shan, Y.S.5
  • 110
    • 80052365527 scopus 로고    scopus 로고
    • Outcomes after curative treatment for cryptogenic cirrhosis-associated hepatocellular carcinoma satisfying the Milan criteria
    • [PMID: 21884248]
    • Takuma Y, Nouso K, Makino Y, Gotoh T, Toshikuni N, Morimoto Y, Shimomura H, Yamamoto H. Outcomes after curative treatment for cryptogenic cirrhosis-associated hepatocellular carcinoma satisfying the Milan criteria. J Gastroenterol Hepatol 2011; 26: 1417-1424 [PMID: 21884248 DOI: 10.1111/j.1440-1746.2011.06775.x]
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 1417-1424
    • Takuma, Y.1    Nouso, K.2    Makino, Y.3    Gotoh, T.4    Toshikuni, N.5    Morimoto, Y.6    Shimomura, H.7    Yamamoto, H.8
  • 111
    • 84865221394 scopus 로고    scopus 로고
    • Clinicopathologic characteristics of patients with non-B non-C hepatitis virus hepatocellular carcinoma after hepatectomy
    • [PMID: 22591698]
    • Kaibori M, Ishizaki M, Matsui K, Kwon AH. Clinicopathologic characteristics of patients with non-B non-C hepatitis virus hepatocellular carcinoma after hepatectomy. Am J Surg 2012; 204: 300-307 [PMID: 22591698 DOI: 10.1016/j.amjsurg.2011.11.014]
    • (2012) Am J Surg , vol.204 , pp. 300-307
    • Kaibori, M.1    Ishizaki, M.2    Matsui, K.3    Kwon, A.H.4


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