Hepatocarcinogenesis in non-alcoholic fatty liver disease in Japan

Journal of Gastroenterology and Hepatology (Australia)

Volumn 28, Issue S4, 2013, Pages 88-92

  Tokushige, Katsutoshi ^a   Hashimoto, Etsuko ^a   Kodama, Kazuhiko ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Hepatocellular carcinoma (HCC); Non alcoholic fatty liver disease (NAFLD); Non alcoholic steatohepatitis (NASH)

Indexed keywords

ALPHA FETOPROTEIN; DECARBOXYPROTHROMBIN; GAMMA GLUTAMYLTRANSFERASE;

AGE; ALCOHOL LIVER CIRRHOSIS; ARTICLE; ASIAN; CANCER PATIENT; CANCER RECURRENCE; CHILD PUGH SCORE; CHRONIC LIVER DISEASE; CLINICAL FEATURE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEPATITIS C; HUMAN; JAPAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; NONALCOHOLIC FATTY LIVER; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SURVIVAL TIME;

HEPATOCELLULAR CARCINOMA (HCC); NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD); NON-ALCOHOLIC STEATOHEPATITIS (NASH);

AGE FACTORS; BIOLOGICAL MARKERS; CARCINOMA, HEPATOCELLULAR; FATTY LIVER; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; JAPAN; LIVER NEOPLASMS; PREVALENCE; PROPORTIONAL HAZARDS MODELS; PROTEIN PRECURSORS; PROTHROMBIN; RISK FACTORS;

EID: 84897654813     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12239     Document Type: Article

References (23)

1. Bosch FX, Ribes J, Díaz M, Cléries R. Primary liver cancer: worldwide incidence and trends. Gastroenterology 2004; 127(5 Suppl. 1): S5-S16.
2. Sherman M. Hepatocellular carcinoma: epidemiology, risk factors and screening. Semin. Liver Dis. 2005; 25: 143-145.
3. Ikai I, Arii S, Okazaki M etal. Report of the 17th nationwide follow-up survey of primary liver cancer in Japan. Hepatol. Res. 2007; 37: 676-691.
4. Chitturi S, Farrell GC, Hashimoto E, Saibara T, Lau GK, Sollano JD, Asia-Pacific Working Party on NAFLD. Non-alcoholic fatty liver disease in the Asia-Pacific region: definitions and overview of proposed guidelines. J. Gastroenterol. Hepatol. 2007; 22: 778-787.
5. Amarapurkar DN, Hashimoto E, Lesmana LA, Sollano JD, Chen PJ, Goh KL, Asia-Pacific Working Party on NAFLD. How common is non-alcoholic fatty liver disease in the Asia-Pacific region and are there local differences? J. Gastroenterol. Hepatol. 2007; 22: 788-793.
6. Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology 2010; 51: 1820-1832.
7. Siegel AB, Zhu AX. Metabolic syndrome and hepatocellular carcinoma: two growing epidemics with a potential link. Cancer 2009; 115: 5651-5661.
8. Shimada M, Hashimoto E, Taniai M etal. Hepatocellular carcinoma in patients with non-alcoholic steatohepatitis. J. Hepatol. 2002; 37: 154-160.
9. Bugianesi E. Non-alcoholic steatohepatitis and cancer. Clin. Liver Dis. 2007; 11: 191-207.
10. Yatsuji S, Hashimoto E, Tobari M, Taniai M, Tokushige K, Shiratori K. Clinical features and outcomes of cirrhosis due to non-alcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C. J. Gastroenterol. Hepatol. 2009; 24: 248-254.
11. Tokushige K, Hashimoto E, Horie Y, Taniai M, Higuchi S. Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease, alcoholic liver disease and chronic liver disease of unknown etiology: report of the Nationwide Survey. J. Gastroenterol. 2011; 46: 1230-1237.
12. Malik SM, Gupte PA, de Vera ME, Ahmad J. Liver transplantation in patients with nonalcoholic steatohepatitis-related hepatocellular carcinoma. Clin. Gastroenterol. Hepatol. 2009; 7: 800-806.
13. Marrero JA, Fontana RJ, Su GL, Conjeevaram HS, Emick DM, Lok AS. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology 2002; 36: 1349-1354.
14. Mandayam S, Jamal MM, Morgan TR. Epidemiology of alcoholic liver disease. Semin. Liver Dis. 2004; 24: 217-232.
15. Bellentani S, Saccoccio G, Costa G etal. Drinking habits as cofactors of risk for alcohol induced liver damage. The Dionysos Study Group. Gut 1997; 41: 845-850.
16. Kawamura Y, Arase Y, Ikeda K etal. Large-scale long-term follow-up study of Japanese patients with non-alcoholic fatty liver disease for the onset of hepatocellular carcinoma. Am. J. Gastroenterol. 2012; 107: 253-261.
17. Kodama K, Tokushige K, Hashimoto E, Taniai M, Shiratori K. Hepatic and extrahepatic malignancies in cirrhosis caused by nonalcoholic steatohepatitis and alcoholic liver disease. Alcohol. Clin. Exp. Res. 2013; 37 (Suppl. 1): E247-252.
18. Sanyal AJ, Banas C, Sargeant C etal. Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C. Hepatology 2006; 43: 682-689.
19. Ascha MS, Hanouneh IA, Lopez R, Tamimi TA, Feldstein AF, Zein NN. The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis. Hepatology 2010; 51: 1972-1978.
20. Hashimoto E, Tokushige K. Hepatocellular carcinoma in non-alcoholic steatohepatitis: growing evidence of an epidemic? Hepatol. Res. 2012; 42: 1-14.
21. Yasui K, Hashimoto E, Komorizono Y etal. Characteristics of patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma. Clin. Gastroenterol. Hepatol. 2011; 9: 428-433.
22. Tokushige K, Hashimoto E, Yatsuji S etal. Prospective study of hepatocellular carcinoma in nonalcoholic steatohepatitis in comparison with hepatocellular carcinoma caused by chronic hepatitis C. J. Gastroenterol. 2010; 45: 960-967.
23. Zen Y, Katayanagi K, Tsuneyama K, Harada K, Araki I, Nakanuma Y. Hepatocellular carcinoma arising in non-alcoholic steatohepatitis. Pathol. Int. 2001; 51: 127-131.