Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs

Journal of Alzheimer's Disease

Volumn 48, Issue 3, 2015, Pages 647-665

  Magistri, Marco ^a   Velmeshev, Dmitry ^a   Makhmutova, Madina ^a   Faghihi, Mohammad Ali ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; amyloid homeostasis; cerebral vasculature; long noncoding RNAs; natural antisense transcripts; RNA sequencing

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; ALLOGRAFT INFLAMMATORY FACTOR 1; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AQUAPORIN 4 ANTIBODY; COMPLEMENTARY RNA; DOUBLECORTIN; LONG UNTRANSLATED RNA; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROFILAMENT M PROTEIN; NEUROFILAMENT PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; RNA BINDING PROTEIN; SUBSTANCE P; TRANSCRIPTOME; UNTRANSLATED RNA;

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN TISSUE; CELL COMMUNICATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; NERVE CELL; NEUROLOGIC DISEASE; PATHOPHYSIOLOGY; PROTEIN HOMEOSTASIS; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; UPREGULATION; VASCULARIZATION; VERY ELDERLY; GENETICS; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; SEQUENCE ANALYSIS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; FEMALE; GENE EXPRESSION PROFILING; HIPPOCAMPUS; HOMEOSTASIS; HUMANS; MALE; REAL-TIME POLYMERASE CHAIN REACTION; RNA, LONG NONCODING; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME;

EID: 84943812484     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150398     Document Type: Article

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