Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1-AS expression

Molecular Medicine Reports

Volumn 10, Issue 3, 2014, Pages 1275-1281

  Liu, Te ^a   Huang, Yongyi ^b   Chen, Jiulin ^a   Chi, Huiying ^a   Yu, Zhihua ^a   Wang, Jian ^a   Chen, Chuan ^a  

^a LONGHUA HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b TONGJI UNIVERSITY   (China)

Author keywords

Amyloid precursor protein; Long noncoding RNAs; Noncoding RNAs; secretase 1; secretase 1 antisense

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; KI 67 ANTIGEN; LONG UNTRANSLATED RNA; MESSENGER RNA; PLASMID DNA; SMALL INTERFERING RNA; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; PEPTIDE FRAGMENT; SECRETASE;

ALZHEIMER DISEASE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MTT ASSAY; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; QUANTITATIVE STUDY; RIBONUCLEASE PROTECTION ASSAY; SENILE PLAQUE; WESTERN BLOTTING; AMYLOID PLAQUE; GENE SILENCING; GENETICS; METABOLISM; PROTEIN PROCESSING; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; GENE SILENCING; HUMANS; KI-67 ANTIGEN; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, LONG NONCODING; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84905449570     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2351     Document Type: Article

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