Sedation of pediatric patients for dental procedures

Pediatric Sedation Outside of the Operating Room: A Multispecialty International Collaboration

Volumn , Issue , 2012, Pages 333-350

  Wilson, Stephen ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84943762746     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-09714-5_16     Document Type: Chapter

References (132)

1. Wilson S. Pharmacological management of the pediatric dental patient. Pediatr Dent. 2004;26(2): 131–6.
2. US Department of Health and Human Services. Oral health in America: a report of the surgeon general. Rockville: DHHS, National Institute of Dental and Craniofacial Research, National Institute of Health; 2000.
3. Berkowitz RJ. Mutans streptococci: acquisition and transmission. Pediatr Dent. 2006;28(2):106–9; discussion 192–8.
4. Caufield PW, Griffen AL. Dental caries. An infectious and transmissible disease. Pediatr Clin North Am. 2000;47(5):1001–19, v.
5. Houpt M. Project USAP 2000 – use of sedative agents by pediatric dentists: a 15-year follow-up survey. Pediatr Dent. 2002;24(4):289–94.
6. Wilson S. A survey of the American Academy of Pediatric Dentistry membership: nitrous oxide and sedation. Pediatr Dent. 1996;18(4):287–93.
7. The American Dental Association. Guidelines for the use of sedation and general anesthesia by dentists: as adopted by the October 2007 ADA House of Delegates. http://www.ada.org/sections/about/pdfs/anesthesia_guidelines.pdf. Accessed 2010.
8. The American Dental Association. Guidelines for teaching pain control and sedation to dentists and dental students: as adopted by the October 2007 ADA House of Delegates. http://www.ada.org/sections/professionalResources/pdfs/anxiety_guidelines.pdf. Accessed 2010.
9. American Academy of Pediatric Dentists (AAPD). Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update. developed through a collaborative effort between the American Academy of Pediatrics and the AAPD. http://www.aapd.org/media/policies.asp. Accessed 2006.
10. Adair SM et al. Survey of behavior management teaching in predoctoral pediatric dentistry programs. Pediatr Dent. 2004;26(2):143–50.
11. Waggoner WF. Conscious sedation in predoctoral pediatric dentistry programs. J Dent Educ. 1986;50(4): 225–9.
12. Wilson S et al. Conscious sedation experiences in graduate pediatric dentistry programs. Pediatr Dent. 2001;23(4):307–14.
13. Cravero JP, Blike GT. Review of pediatric sedation. Anesth Analg. 2004;99(5):1355–64.
14. Wilson S. Chloral hydrate and its effects on multiple physiological parameters in young children: a doseresponse study. Pediatr Dent. 1992;14(3):171–7.
15. Badalaty MM et al. A comparison of chloral hydrate and diazepam sedation in young children. Pediatr Dent. 1990;12(1):33–7.
16. Religa ZC et al. Association between bispectral analysis and level of conscious sedation of pediatric dental patients. Pediatr Dent. 2002;24(3):221–6.
17. Leelataweedwud P, Vann WF Jr. Adverse events and outcomes of conscious sedation for pediatric patients: study of an oral sedation regimen. J Am Dent Assoc. 2001;132(11):1531–9; quiz 1596.
18. Fishbaugh DF et al. Relationship of tonsil size on an airway blockage maneuver in children during sedation. Pediatr Dent. 1997;19(4):277–81.
19. Sanders BJ, Potter RH, Avery DR. The effect of sleep on conscious sedation. J Clin Pediatr Dent. 1994;18(3): 211–4.
20. Wilson S. Facial electromyography and chloral hydrate in the young dental patient. Pediatr Dent. 1993;15(5):343–7.
21. Chowdhury J, Vargas KG. Comparison of chloral hydrate, meperidine, and hydroxyzine to midazolam regimens for oral sedation of pediatric dental patients. Pediatr Dent. 2005;27(3):191–7.
22. Martinez D, Wilson S. Children sedated for dental care: a pilot study of the 24-hour postsedation period. Pediatr Dent. 2006;28(3):260–4.
23. Lochary ME et al. Temperament as a predictor of behavior for conscious sedation in dentistry. Pediatr Dent. 1993;15(5):348–52.
24. Musial KM et al. Comparison of the efficacy of oral midazolam alone versus midazolam and meperidine in the pediatric dental patient. Pediatr Dent. 2003;25(5):468–74.
25. Marshall WR, Weaver BD, McCutcheon P. A study of the effectiveness of oral midazolam as a dental pre-operative sedative and hypnotic. Spec Care Dentist. 1999;19(6):259–66.
26. Shapira J et al. The effectiveness of midazolam and hydroxyzine as sedative agents for young pediatric dental patients. ASDC J Dent Child. 1996;63(6): 421–5.
27. Wilson KE, Girdler NM, Welbury RR. Randomized, controlled, cross-over clinical trial comparing intravenous midazolam sedation with nitrous oxide sedation in children undergoing dental extractions. Br J Anaesth. 2003;91(6):850–6.
28. Fuks AB et al. Assessment of two doses of intranasal midazolam for sedation of young pediatric dental patients. Pediatr Dent. 1994;16(4):301–5.
29. Houpt M et al. Effects of chloral hydrate on nitrous oxide sedation of children. Pediatr Dent. 1989;11(1): 26–9.
30. Sharma RK, Pinto RR, Mirchandani NN. Use of sedation analgesia for pediatric dentistry. J Indian Soc Pedod Prev Dent. 1992;10(1):28–32.
31. Ram D, et al. The effect of metoclopramide and hydroxyzine in sedation of infants undergoing dental treatment. ASDC J Dent Child. 1999;66(1): 49–52, 13.
32. Houpt MI et al. Effects of nitrous oxide on diazepam sedation of young children. Pediatr Dent. 1996;18(3): 236–41.
33. Poorman TL, Farrington FH, Mourino AP. Comparison of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients. Pediatr Dent. 1990;12(5):288–91.
34. Meyer ML, Mourino AP, Farrington FH. Comparison of triazolam to a chloral hydrate/hydroxyzine combination in the sedation of pediatric dental patients. Pediatr Dent. 1990;12(5):283–7.
35. Brandes DA et al. A comparison of opinions from parents of disabled and non-disabled children on behavior management techniques used in dentistry. Spec Care Dentist. 1995;15(3):119–23.
36. Lam C et al. Midazolam premedication in children: a pilot study comparing intramuscular and intranasal administration. Anesth Prog. 2005;52(2):56–61.
37. Shapira J et al. Comparison of oral midazolam with and without hydroxyzine in the sedation of pediatric dental patients. Pediatr Dent. 2004;26(6):492–6.
38. Vargas KG et al. Use of restraint and management style as parameters for defining sedation success: a survey of pediatric dentists. Pediatr Dent. 2007;29(3): 220–7.
39. Cote CJ, Wilson S. Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update. Pediatrics. 2006;118(6):2587–602.
40. Arnrup K et al. Treatment outcome in subgroups of uncooperative child dental patients: an exploratory study. Int J Paediatr Dent. 2003;13(5):304–19.
41. Jensen B, Stjernqvist K. Temperament and acceptance of dental treatment under sedation in preschool children. Acta Odontol Scand. 2002;60(4):231–6.
42. Acs G, Musson CA, Burke MJ. Current teaching of restraint and sedation in pediatric dentistry: a survey of program directors. Pediatr Dent. 1990;12(6): 364–7.
43. Adair SM et al. Survey of behavior management teaching in pediatric dentistry advanced education programs. Pediatr Dent. 2004;26(2):151–8.
44. Houpt M. Report of project USAP: the use of sedative agents in pediatric dentistry. ASDC J Dent Child. 1989;56(4):302–9.
45. Houpt M. Project USAP the use of sedative agents in pediatric dentistry: 1991 update. Pediatr Dent. 1993;15(1):36–40.
46. Chen JW, Seybold SV, Yazdi H. Assessment of the effects of 2 sedation regimens on cardiopulmonary parameters in pediatric dental patients: a retrospective study. Pediatr Dent. 2006;28(4):350–6.
47. Cathers JW et al. A comparison of two meperidine/hydroxyzine sedation regimens for the uncooperative pediatric dental patient. Pediatr Dent. 2005; 27(5):395–400.
48. Song YU, Webb MD. Comparison of the effect of orally versus submucosally administered meperidine on the behavior of pediatric dental patients: a retrospective study. Anesth Prog. 2003;50(3):129–33.
49. Roberts SM et al. Evaluation of morphine as compared to meperidine when administered to the moderately anxious pediatric dental patient. Pediatr Dent. 1992;14(5):306–13.
50. Sams DR et al. Behavioral assessments of two drug combinations for oral sedation. Pediatr Dent. 1993; 15(3):186–90.
51. Nathan JE, West MS. Comparison of chloral hydratehydroxyzine with and without meperidine for management of the difficult pediatric patient. ASDC J Dent Child. 1987;54(6):437–44.
52. Sanders BJ, Avery DR. The effect of sleep on conscious sedation: a follow-up study [published erratum appears in J Clin Pediatr Dent. 1997 Summer;21(4):356]. J Clin Pediatr Dent. 1997; 21(2):131–4.
53. Leelataweewud P et al. The physiological effects of supplemental oxygen versus nitrous oxide/oxygen during conscious sedation of pediatric dental patients. Pediatr Dent. 2000;22(2):125–33.
54. Wilson S et al. A retrospective study of chloral hydrate, meperidine, hydroxyzine, and midazolam regimens used to sedate children for dental care. Pediatr Dent. 2000;22(2):107–12.
55. Rohlfing GK et al. The effect of supplemental oxygen on apnea and oxygen saturation during pediatric conscious sedation. Pediatr Dent. 1998;20(1):8–16.
56. Campbell RL et al. Comparison of oral chloral hydrate with intramuscular ketamine, meperidine, and promethazine for pediatric sedation – preliminary report. Anesth Prog. 1998;45(2):46–50.
57. Croswell RJ et al. A comparison of conventional versus electronic monitoring of sedated pediatric dental patients. Pediatr Dent. 1995;17(5):332–9.
58. Sams DR, Thornton JB, Wright JT. The assessment of two oral sedation drug regimens in pediatric dental patients. ASDC J Dent Child. 1992;59(4):306–12.
59. Hasty MF et al. Conscious sedation of pediatric dental patients: an investigation of chloral hydrate, hydroxyzine pamoate, and meperidine vs. chloral hydrate and hydroxyzine pamoate. Pediatr Dent. 1991;13(1):10–9.
60. Haney KL, McWhorter AG, Seale NS. An assessment of the success of meperidine and promethazine sedation in medically compromised children. ASDC J Dent Child. 1993;60(4–5):288–94.
61. Alfonzo-Echeverri EC et al. Oral ketamine for pediatric outpatient dental surgery sedation. Pediatr Dent. 1993;15(3):182–5.
62. Nathan JE, Vargas KG. Oral midazolam with and without meperidine for management of the difficult young pediatric dental patient: a retrospective study. Pediatr Dent. 2002;24(2):129–38.
63. Moody Jr EH, Mourino AP, Campbell RL. The therapeutic effectiveness of nitrous oxide and chloral hydrate administered orally, rectally, and combined with hydroxyzine for pediatric dentistry. ASDC J Dent Child. 1986;53(6):425–9.
64. Houpt MI et al. Comparison of chloral hydrate with and without promethazine in the sedation of young children. Pediatr Dent. 1985;7(1):41–6.
65. Avalos-Arenas V et al. Is chloral hydrate/hydroxyzine a good option for paediatric dental outpatient sedation? Curr Med Res Opin. 1998;14(4):219–26.
66. Wilson S et al. The effect of electronic dental anesthesia on behavior during local anesthetic injection in the young, sedated dental patient. Pediatr Dent. 1999; 21(1):12–7.
67. Dallman JA, Ignelzi Jr MA, Briskie DM. Comparing the safety, efficacy and recovery of intranasal midazolam vs. oral chloral hydrate and promethazine. Pediatr Dent. 2001;23(5):424–30.
68. Reeves ST et al. A randomized double-blind trial of chloral hydrate/hydroxyzine versus midazolam/acetaminophen in the sedation of pediatric dental outpatients. ASDC J Dent Child. 1996;63(2): 95–100.
69. McCann W et al. The effects of nitrous oxide on behavior and physiological parameters during conscious sedation with a moderate dose of chloral hydrate and hydroxyzine. Pediatr Dent. 1996;18(1): 35–41.
70. Haas DA et al. A pilot study of the efficacy of oral midazolam for sedation in pediatric dental patients. Anesth Prog. 1996;43(1):1–8.
71. Needleman HL, Joshi A, Griffith DG. Conscious sedation of pediatric dental patients using chloral hydrate, hydroxyzine, and nitrous oxide – a retrospective study of 382 sedations. Pediatr Dent. 1995;17(7): 424–31.
72. Duncan WK, De Ball S, Perkins TM. Chloral hydrate sedation: a simple technique. Compendium. 1994;15(7):884, 886–8, 890 passim; quiz 894.
73. Davila JM et al. Comparison of the sedative effectiveness of two pharmacological regimens. ASDC J Dent Child. 1994;61(4):276–81.
74. Iwasaki J et al. An investigation of capnography and pulse oximetry as monitors of pediatric patients sedated for dental treatment. Pediatr Dent. 1989;11(2):111–7.
75. Kantovitz KR, Puppin-Rontani RM, Gaviao MB. Sedative effect of oral diazepam and chloral hydrate in the dental treatment of children. J Indian Soc Pedod Prev Dent. 2007;25(2):69–75.
76. Torres-Perez J et al. Comparison of three conscious sedation regimens for pediatric dental patients. J Clin Pediatr Dent. 2007;31(3):183–6.
77. Myers GR et al. Effect of submucosal midazolam on behavior and physiologic response when combined with oral chloral hydrate and nitrous oxide sedation. Pediatr Dent. 2004;26(1):37–43.
78. Alhashemi JA, Daghistani MF. Effect of intraoperative intravenous acetaminophen vs. intramuscular meperidine on pain and discharge time after paediatric dental restoration. Eur J Anaesthesiol. 2007;24(2): 128–33.
79. Fukuta O et al. The sedative effects of intranasal midazolam administration in the dental treatment of patients with mental disabilities. Part 2: optimal concentration of intranasal midazolam. J Clin Pediatr Dent. 1994;18(4):259–65.
80. Krafft TC et al. Experience with midazolam as sedative in the dental treatment of uncooperative children. ASDC J Dent Child. 1993;60(4–5):295–9.
81. Lloyd CJ, Alredy T, Lowry JC. Intranasal midazolam as an alternative to general anaesthesia in the management of children with oral and maxillofacial trauma. Br J Oral Maxillofac Surg. 2000;38(6):593–5.
82. Singh N et al. A comparative evaluation of oral midazolam with other sedatives as premedication in pediatric dentistry. J Clin Pediatr Dent. 2002;26(2):161–4.
83. Erlandsson AL et al. Conscious sedation by oral administration of midazolam in paediatric dental treatment. Swed Dent J. 2001;25(3):97–104.
84. Roelofse JA, Joubert JJ, Roelofse PG. A doubleblind randomized comparison of midazolam alone and midazolam combined with ketamine for sedation of pediatric dental patients. J Oral Maxillofac Surg. 1996;54(7):838–44; discussion 845–6.
85. Kupietzky A, Holan G, Shapira J. Intranasal midazolam better at effecting amnesia after sedation than oral hydroxyzine: a pilot study. Pediatr Dent. 1996;18(1): 32–4.
86. Silver T, Wilson C, Webb M. Evaluation of two dosages of oral midazolam as a conscious sedation for physically and neurologically compromised pediatric dental patients. Pediatr Dent. 1994;16(5): 350–9.
87. Hartgraves PM, Primosch RE. An evaluation of oral and nasal midazolam for pediatric dental sedation. ASDC J Dent Child. 1994;61(3):175–81.
88. Fukuta O et al. The sedative effect of intranasal midazolam administration in the dental treatment of patients with mental disabilities. Part 1. The effect of a 0.2 mg/kg dose. J Clin Pediatr Dent. 1993;17(4): 231–7.
89. Kil N et al. The effects of midazolam on pediatric patients with asthma. Pediatr Dent. 2003;25(2): 137–42.
90. Hulland SA, Freilich MM, Sandor GK. Nitrous oxide-oxygen or oral midazolam for pediatric outpatient sedation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;93(6):643–6.
91. Lima AR, da Costa LR, da Costa PS. A randomized, controlled, crossover trial of oral midazolam and hydroxyzine for pediatric dental sedation. Pesqui Odontol Bras. 2003;17(3):206–11.
92. Tamura M et al. Oral premedication with fentanyl may be a safe and effective alternative to oral midazolam. Eur J Anaesthesiol. 2003;20(6):482–6.
93. Pisalchaiyong T et al. Comparison of the effectiveness of oral diazepam and midazolam for the sedation of autistic patients during dental treatment. Pediatr Dent. 2005;27(3):198–206.
94. Wan K, Jing Q, Zhao JZ. Evaluation of oral midazolam as conscious sedation for pediatric patients in oral restoration. Chin Med Sci J. 2006;21(3): 163–6.
95. Cote CJ et al. Adverse sedation events in pediatrics: analysis of medications used for sedation. Pediatrics. 2000;106(4):633–44.
96. Karl HW et al. Pharmacokinetics of oral triazolam in children. J Clin Psychopharmacol. 1997;17(3): 169–72.
97. Quarnstrom FC, Milgrom P, Moore PA. Experience with triazolam in preschool children. Anesth Pain Control Dent. 1992;1(3):157–9.
98. Smith BM, Cutilli BJ, Saunders W. Oral midazolam: pediatric conscious sedation. Compend Contin Educ Dent. 1998;19(6):586–8, 590, 592.
99. Abrams R et al. Safety and effectiveness of intranasal administration of sedative medications (ketamine, midazolam, or sufentanil) for urgent brief pediatric dental procedures. Anesth Prog. 1993;40(3): 63–6.
100. van der Bijl P, Roelofse JA, Stander IA. Rectal ketamine and midazolam for premedication in pediatric dentistry. J Oral Maxillofac Surg. 1991;49(10): 1050–4.
101. Alderson PJ, Lerman J. Oral premedication for paediatric ambulatory anaesthesia: a comparison of midazolam and ketamine. Can J Anaesth. 1994;41(3): 221–6.
102. Roelofse JA et al. An evaluation of the effect of oral ketamine and standard oral premedication in the sedation of paediatric dental patients. J Dent Assoc S Afr. 1996;51(4):197–201.
103. Sullivan DC, Wilson CF, Webb MD. A comparison of two oral ketamine-diazepam regimens for the sedation of anxious pediatric dental patients. Pediatr Dent. 2001;23(3):223–31.
104. Roelofse JA, Louw LR, Roelofse PG. A double blind randomized comparison of oral trimeprazine-methadone and ketamine-midazolam for sedation of pediatric dental patients for oral surgical procedures. Anesth Prog. 1998;45(1):3–11.
105. Reinemer HC, Wilson CF, Webb MD. A comparison of two oral ketamine-diazepam regimens for sedating anxious pediatric dental patients. Pediatr Dent. 1996;18(4):294–300.
106. Okamoto GU, Duperon DF, Jedrychowski JR. Clinical evaluation of the effects of ketamine sedation on pediatric dental patients. J Clin Pediatr Dent. 1992;16(4):253–7.
107. Stephens AJ, Sapsford DJ, Curzon ME. Intravenous sedation for handicapped dental patients: a clinical trial of midazolam and propofol. Br Dent J. 1993; 175(1):20–5.
108. Milnes AR, Maupome G, Cannon J. Intravenous sedation in pediatric dentistry using midazolam, nalbuphine and droperidol. Pediatr Dent. 2000;22(2): 113–9.
109. Veerkamp JS, Porcelijn T, Gruythuysen RJ. Intravenous sedation for outpatient treatment of child dental patients: an exploratory study. ASDC J Dent Child. 1997;64(1):48–54.
110. Barr EB, Wynn RL. IV sedation in pediatric dentistry: an alternative to general anesthesia. Pediatr Dent. 1992;14(4):251–5.
111. Milnes AR. Intravenous procedural sedation: an alternative to general anesthesia in the treatment of early childhood caries. J Can Dent Assoc. 2003;69(5): 298–302.
112. Lu DP, Lu GP, Reed JF III. Safety, efficacy, and acceptance of intramuscular sedation: assessment of 900 dental cases. Compendium. 1994;15(11):1348-1350, 1352 passim; quiz 1362.
113. Koroluk LD. Dental anxiety in adolescents with a history of childhood dental sedation. ASDC J Dent Child. 2000;67(3):200–5, 161.
114. Downs AT, et al. A comparative study of midazolam to meperidine/promethazine as an IM sedative technique for the pediatric dental patient. ASDC J Dent Child. 1997;64(3):197–200, 165, 228.
115. al-Rakaf H et al. Intra-nasal midazolam in conscious sedation of young paediatric dental patients. Int J Paediatr Dent. 2001;11(1):33–40.
116. Fukuta O et al. Intranasal administration of midazolam: pharmacokinetic and pharmacodynamic properties and sedative potential. ASDC J Dent Child. 1997;64(2):89–98.
117. Lee-Kim SJ et al. Nasal versus oral midazolam sedation for pediatric dental patients. J Dent Child (Chic). 2004;71(2):126–30.
118. Primosch RE, Bender F. Factors associated with administration route when using midazolam for pediatric conscious sedation. ASDC J Dent Child. 2001;68(4):233–8, 228.
119. Heard C et al. A comparison of four sedation techniques for pediatric dental surgery. Paediatr Anaesth. 2010;20(10):924–30.
120. Klein U et al. Nitrous oxide concentrations in the posterior nasopharynx during administration by nasal mask. Pediatr Dent. 2004;26(5):410–6.
121. Guo TZ et al. Antinociceptive response to nitrous oxide is mediated by supraspinal opiate and spinal alpha 2 adrenergic receptors in the rat. Anesthesiology. 1996;85(4):846–52.
122. Roberts GJ, Wignall BK. Efficacy of the laryngeal reflex during oxygen-nitrous oxide sedation (relative analgesia). Br J Anaesth. 1982;54(12):1277–81.
123. Kupietzky A et al. Fasting state and episodes of vomiting in children receiving nitrous oxide for dental treatment. Pediatr Dent. 2008;30(5):414–9.
124. Houck WR, Ripa LW. Vomiting frequency in children administered nitrous oxide-oxygen in analgesic doses. ASDC J Dent Child. 1971;28(6):404–6.
125. Malamed SF. Inhalation sedation: complications. 4th ed. St. Louis: CV Mosby; 2003.
126. Jastak JT, Pallasch T. Death after chloral hydrate sedation: report of case. J Am Dent Assoc. 1988;116(3):345–8.
127. Houpt M. Death following oral sedation. ASDC J Dent Child. 1988;55(2):123–4.
128. National Institutes of Health. Consensus development conference statement on anesthesia and sedation in the dental office. J Am Dent Assoc. 1985;111(1): 90–3.
129. American Academy of Pediatric Dentistry. Guidelines for the elective use of conscious sedation, deep sedation, and general anesthesia in pediatric patients. ASDC J Dent Child. 1986;53(1):21–2.
130. American Academy of Pediatrics. Guidelines for the elective use of conscious sedation, deep sedation, and general anesthesia in pediatric patients. Committee on drugs. Section on anesthesiology. Pediatrics. 1985;76(2):317–21.
131. Cote CJ. Sedation for the pediatric patient. A review. Pediatr Clin North Am. 1994;41(1):31–58.
132. Cote CJ. Sedation protocols – why so many variations? Pediatrics. 1994;94(3):281–3.