A randomized double-blind trial of chloral hydrate/hydroxyzine versus midazolam/acetaminophen in the sedation of pediatric dental outpatients

Journal of Dentistry for Children

Volumn 63, Issue 2, 1996, Pages 95-100

  Reeves, Scott T ^a   Wiedenfeld, Kenneth R ^a   Wrobleski, Jan ^a   Hardin, Cynthia L ^a   Pinosky, Mark L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Chloral hydrate hydroxyzine; Midazolam acetaminophen; Sedation

Indexed keywords

CHLORAL HYDRATE; HYDROXYZINE; MIDAZOLAM; PARACETAMOL;

ARTICLE; CHI SQUARE DISTRIBUTION; CHILD; CHILD BEHAVIOR; CLINICAL TRIAL; CONSCIOUS SEDATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DENTAL ANESTHESIA; DENTAL CARE; DOUBLE BLIND PROCEDURE; DRUG COMBINATION; DRUG EFFECT; FEMALE; HUMAN; MALE; METHODOLOGY; NONPARAMETRIC TEST; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL;

ACETAMINOPHEN; ANESTHESIA, DENTAL; CHI-SQUARE DISTRIBUTION; CHILD; CHILD BEHAVIOR; CHILD, PRESCHOOL; CHLORAL HYDRATE; CONSCIOUS SEDATION; DENTAL CARE FOR CHILDREN; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; HUMANS; HYDROXYZINE; MALE; MIDAZOLAM; STATISTICS, NONPARAMETRIC;

EID: 0030099699     PISSN: 15518949     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Duncan, W.K.; Pruhs, R.J.; Ashraf, M.H. et al: Chloral hydrate and other drugs used in sedating young children: a survey of American Academy of Pedodontics Diplomates. Pediatr Dent, 5:252-256, December 1983.
2. Houpt, M.l.: Report of project USAP: The use of sedative agents in pediatric dentistry. J Dent Child, 56:302-309 July-August 1989.
3. Houpt, M.l.: Project USAP - Part Ill: Practice by heavy users of sedation in pediatric dentistry. J Dent Child, 60:183-185; May-June 1993.
4. Nathan, J.E.: Management of the refractory young child with chloral hydrate: Dosage selection. J Dent Child, 54:93-100; March-April 1987.
5. Badalaty, M.M.; Houpt, M.l.; Koenigsberg, S.R. et al: Comparison of chloral hydrate and diazepam sedation in young children. Pediatr Dent, 12:33-37, February 1990.
6. Meyer, M.L.; Mourine, A.P.; Farrington, F.H.: Comparison of triazolam to a chloral hydrate/hydroxyzine combination in the sedation of pediatric dental patients. Pediatr Dent 12:283-287, September-October 1990.
7. Wilson, S.: Chloral hydrate and its effects on multiple physiological parameters in young children: a dose-response study. Pediatr Dent, 14:171-177, May-June 1992.
8. Houpt, M.l.; Sheskin, R.B.; Koenigsberg, S.R. et al: Assessing chloral hydrate dosage for young children. J Dent Child, 52:364-369; September-October 1985.
9. Tobias, M.; Lipshultz, D.H.; Album, M.M.: A study of three pre-operative sedative combinations. J Dent Child, 42:453-459, November-December 1975.
10. Nathan, J.E. and West, M.S.: Comparison of chloral hydrate-hydroxyzine with and without meperidine for management of the difficult pediatric patient. J Dent Child, 54:437-444, November-December 1987.
11. Sams, D.R.; Thornton, J.B.; Wright, J.T.: The assessment of two oral sedation drug regimens in pediatric dental patients. J Dent Child, 59:306-312, July-August 1992.
12. Poorman, T.L.; Farrington, F.H.; Mourino, A.P.: Comparison of a chloral hydrate/hydroxyzine combination with and without meperidine in the sedation of pediatric dental patients. Pediatr Dent, 12: 188-291, September-October 1990.
13. Sams, D.R.; Cook, E.W.; Jackson, J.G. et al: Behavioral assessments of two drug combinations for oral sedation. Pediatr Dent, 15:186-190, May-June 1993.
14. Committee on Drugs and Committee on Environmental Health: Use of chloral hydrate for sedation in children. Pediatrics, 92:471-473, September 1993.
15. Stephens, A.J.; Sapsford, D.J.; Curzon, M.E.J.: Intravenous sedation for handicapped dental patients: a clinical trial of midazolam and propofol. Brit Dent J, 175:20-25, July 1993.
16. Luyk, N.H. and Whitley, B.D.: Efficacy of oral midazolam prior to intravenous sedation for the removal of third molars. Int J Oral Maxillofac Surg, 20:264-267, 1991.
17. Roelofse, J.A. and Van Der Bijl, P.: Comparison of rectal midazolam and diazepam for premedication in pediatric dental patients. J Oral Maxillofac Surg, 51:525-529, May 1993.
18. Kraffl, T.C.; Kramer, N.; Kunzelmann, K.H. et al: Experience with midazolam as sedative in the dental treatment of uncooperative children. J Dent Child, 60:295-299, July-October 1993.
19. Karl, H.W.; Rosenberger, J.L.; Larach, M.G. et al: Transmucosal administration of midazolam for premedication of pediatric patients. Anesthesiology, 78:885-891, May 1993.
20. Fuks, A.B.; Kaufman, E.; Ram, D. et al: Assessment of two doses of intranasal midazolam for sedation of young pediatric dental patients. Pediatr Dent, 16:301-305, July-August 1994.
21. Hartgraves, P.M. and Primosch, R.E.: An evaluation of oral and nasal midazolam for pediatric dental sedation. J Dent Child, 61: 175-181, May-June 1994.
22. Silver, T.; Wilson, C.; Webb, M.: Evaluation of two dosages of oral midazolam as a conscious sedation for physically and neurologically compromised pediatric dental patients. Pediatr Dent, 16:350-359, September-October 1994.
23. Reld, L.H.; Negus, J.B.; White, P.F.: Oral midazolam preanesthetic medication in pediatric outpatients. Anesthesiology, 73:831-834, November 1990.
24. Weldon, B.C.; Watcha, M.F.; White, P.F.: Oral midazolam in children: effect of time and adjunctive therapy. Anesth Analg, 75:51-55, January 1992.
25. Kupietzky, A. and Houpt, M.l.: Midazolam: a review of its use for conscious sedation of children. Pediatr Dent, 15:237-241, July-August 1993.
26. Cooper, A.C.; Quinn, P.D.; MacAfee, K. et al: Reversing intravenous sedation with flumazenil. Oral Surg Oral Med Oral Pathol, 72:2-9, July 1991.
27. Stoelting, R.K.: Pharmacology & Physiology in Anesthetic Practice. Philadelphia: J.B. Lippincott Company, 1991, p131.
28. Frankl, S.N.; Shiere, F.Z.; Fozels, H.C.: Should the parent remain with the child in the dental operatory? J Dent Child, 29:150-163, Second Quarter 1962.
29. Guidelines for the elective use of pharmacologic conscious sedation and deep sedation in pediatric dental patients. Pediatr Dent, 15:297-301, July-August 1993.
30. Feld, L.H.; Negus, J.B.; White, P.F.: Oral midazolam preanesthetic medication in pediatric outpatients. Anesthesiology, 73:831-834, November 1990.
31. McMillan, C.O. and Spahr-Schopfe, I.A.: Premedication of children with oral midazolam. Can J Anaesth, 39:545-550, July 1992.
32. Hasty, M.F.; Vann, W.F.; Dilley, D.C. et al: Conscious sedation of pediatric dental patients: an investigation of chloral hydrate, hydroxyzine pamoate, and meperidine vs. chloral hydrate and hydroxyzine pamoate. Pediatr Dent, 13:10-19, January-February 1991.