Stem cells as hormone targets that lead to increased cancer susceptibility

Endocrinology (United States)

Volumn 156, Issue 10, 2015, Pages 3451-3457

  Prins, Gail S ^a   Calderon Gierszal, Esther L ^a   Hu, Wen Yang ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOCRINE DISRUPTOR; ESTROGEN; HORMONE; 4,4' ISOPROPYLIDENEDIPHENOL; BENZHYDRYL DERIVATIVE; PHENOL DERIVATIVE;

CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CYTOPLASM; EMBRYONIC STEM CELL; ENVIRONMENTAL FACTOR; HUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROSTATE; PROSTATE EPITHELIUM; REVIEW; STEM CELL; ANIMAL; CELL DIFFERENTIATION; CELL LINEAGE; CYTOLOGY; DISEASE PREDISPOSITION; DRUG EFFECTS; ENDOCRINE SYSTEM; GENETICS; MALE; MESENCHYMAL STROMA CELL; METABOLISM; MOUSE; NEOPLASM; NUDE MOUSE; PATHOLOGY; RISK FACTOR;

ANIMALS; BENZHYDRYL COMPOUNDS; CELL DIFFERENTIATION; CELL LINEAGE; DISEASE SUSCEPTIBILITY; ENDOCRINE DISRUPTORS; ENDOCRINE SYSTEM; ESTROGENS; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, NUDE; NEOPLASMS; PHENOLS; PROSTATE; RISK FACTORS; STEM CELLS;

EID: 84943635503     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1357     Document Type: Review

References (43)

1. Weissman IL. Stem cells: units of development, units of regeneration, and units in evolution. Cell. 2000;100(1):157-168.
2. Spence JR, Mayhew CN, Rankin SA, et al. Directed differentiation ofhumanpluripotent stem cells into intestinal tissue in vitro. Nature. 2011;470(7332):105-109.
3. Wicha MS. Targeting breast cancer stem cells. Breast (Edinburgh, Scotland). 2009;18(suppl 3):S56 -S58.
4. Fulawka L, Donizy P, Halon A. Cancer stem cells-the current status of an old concept: literature review and clinical approaches. Biol Res. 2014;47(1):66.
5. Clarke RB, Spence K, Anderson E, Howell A, Okano H, Potten CS. A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev Biol. 2005;277(2):443-456.
6. Asselin-Labat ML, Vaillant F, Sheridan JM, et al. Control of mammary stem cell function by steroid hormone signalling. Nature. 2010;465(7299):798-802.
7. Visvader JE, Stingl J. Mammary stem cells and the differentiation hierarchy: current status and perspectives. Genes Dev. 2014;28(11): 1143-1158.
8. Joshi PA, Jackson HW, Beristain AG, et al. Progesterone induces adult mammary stem cell expansion. Nature. 2010;465(7299):803-807.
9. Graham JD, Mote PA, Salagame U, et al. DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast. Endocrinology. 2009;150(7):3318-3326.
10. Pal B, Bouras T, Shi W, et al. Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2. Cell Rep. 2013;3(2):411-426.
11. Hu WY, Shi GB, Lam HM, et al. Estrogen-initiated transformation of prostate epithelium derived from normal human prostate stemprogenitor cells. Endocrinology. 2011;152(6):2150-2163.
12. Hu WY, Shi GB, Hu DP, Nelles JL, Prins GS. Actions of endocrine disrupting chemicals on human prostate stem/progenitor cells and prostate cancer risk. Mol Cell Endocrinol. 2012;354(1-2):63-73.
13. Prins GS, Hu WY. Prostate stem cells, hormones and development. In: Cramer SD, ed. Stem Cells and Prostate Cancer. Vol VII. New York, NY: Springer LLC; 2013:1-20.
14. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63(1):11-30.
15. Prins GS, Putz O. Molecular signaling pathways that regulate prostate gland development. Differentiation. 2008;76(6):641-659.
16. Adams JY, Leav I, Lau KM, Ho SM, Pflueger SM. Expression of estrogen receptor beta in the fetal, neonatal, and prepubertal human prostate. Prostate. 2002;52(1):69-81.
17. Henderson BE, Bernstein L, Ross RK, Depue RH, Judd HL. The early in utero oestrogen and testosterone environment of blacks and whites: potential effects on male offspring. Br J Cancer. 1988;57(2): 216-218.
18. Ekbom A. Growing evidence that several human cancers may originate in utero. Cancer Biol. 1998;8:237-244.
19. Calafat AM, Ye X, Wong LY, Reidy JA, Needham LL. Exposure of the US population to bisphenolAand 4-tertiary-octylphenol: 2003-2004. Environ Health Prospect. 2008;116(1):39-44.
20. Gerona RR, Woodruff TJ, Dickenson CA, et al. BPA, BPA glucuronide, and BPA sulfate in mid-gestation umbilical cord serum in a northern California cohort. Environ Sci Technol. 2013;47(21): 12477-12485.
21. Prins GS, Birch L, Tang WY, Ho SM. Developmental estrogen exposures predispose to prostate carcinogenesis with aging. Reprod Toxicol. 2007;23(3):374-382.
22. Ho SM, Tang WY, Belmonte J, Prins GS. Developmental exposure to estradiol and bisphenol A (BPA) increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant (PDE4D4) in the rat prostate. Cancer Res. 2006; 66(11):5624-5632.
23. Prins GS, Ye SH, Birch L, Ho SM, Kannan K. Serum Bisphenol A pharmacokinetics and prostatic responses following oral and subcutaneous exposures in neonatal Sprague-Dawley rats. Reprod Toxicol. 2011;31(1):1-9.
24. YeanWongRL,WangQ, Trevino LS, et al. Identification of Secretaglobin Scgb2a1 as a target for developmental reprogramming by BPA in the rat prostate. Epigenetics. 2015;10(2):127-134.
25. Kaufman JM, Vermeulen A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev. 2005; 26:833-875.
26. Chakravarty D, Sboner A, Nair SS, et al. The oestrogen receptor β-regulated lncRNA NEAT1 is a critical modulator of prostate cancer. Nat Commun. 2014;5:5383.
27. Tang WY, Morey LM, Cheung YY, Birch L, Prins GS, Ho SM. Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life. Endocrinology. 2012;153(1):42-55.
28. Prins GS, Hu WY, Shi GB, et al. Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium. Endocrinology. 2014; 155(3):805-817.
29. Ho SM, Cheong A, Lam HM, et al. Exposure of human prostaspheres to bisphenol A epigenetically regulates SNORD family noncoding RNAs via histone modification. Endocrinology. [published ahead of print August 6, 2015]. doi: 10.1210/en.2015-1067
30. Mikkelsen TS, Ku M, Jaffe DB, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 2007;448:553-560.
31. Calderon-Gierszal EL, Prins GS. Directed differentiation of human embryonic stem cells into prostate organoids in vitro and its perturbation by low-dose bisphenolAexposure. PloS One. 2015;10(7): e0133238.
32. Tomasetti C, Vogelstein B. Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science (New York, NY). 2015;347(6217):78-81.
33. Taylor RA, Cowin PA, Cunha GR, et al. Formation of human prostate tissue from embryonic stem cells. Nat Methods. 2006;3(3):179-181.
34. Saffarini CM, McDonnell-Clark EV, Amin A, Huse SM, Boekelheide K. Developmental exposure to estrogen alters differentiation and epigenetic programming in a human fetal prostate xenograft model. PloS One. 2015;10(3):e0122290.
35. Weng YI, Hsu PY, Liyanarachchi S, et al. Epigenetic influences of low-dose bisphenolAin primary human breast epithelial cells. Toxicol Appl Pharmacol. 2010;248(2):111-121.
36. Yang L, Luo L, JiW,et al. Effect of low dose bisphenolAon the early differentiation of human embryonic stem cells into mammary epithelial cells. Toxicol Lett. 2013;218(3):187-193.
37. Okada M, Murase K, Makino A, et al. Effects of estrogens on proliferation and differentiation of neural stem/progenitor cells. Biomed Res (Tokyo, Japan). 2008;29(3):163-170.
38. Okada M, Makino A, Nakajima M, Okuyama S, Furukawa S, Furukawa Y. Estrogen stimulates proliferation and differentiation of neural stem/progenitor cells through different signal transduction pathways. Int J Mol Sci. 2010;11(10):4114-4123.
39. Baik I, Devito WJ, Ballen K, et al. Association of fetal hormone levels with stem cell potential: evidence for early life roots of human cancer. Cancer Res. 2005;65(1):358-363.
40. Vrooman LA, Oatley JM, Griswold JE, Hassold TJ, Hunt PA. Estrogenic exposure alters the spermatogonial stem cells in the developing testis, permanently reducing crossover levels in the adult. PLoS Genet. 2015;11(1):e1004949.
41. Li X, Ycaza J, Blumberg B. The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor β to induce adipogenesis in murine 3T3-L1 preadipocytes. J Steroid Biochem Mol Biol. 2011;127(1-2):9-15.
42. Xu Y, Tokar EJ, Sun Y, Waalkes MP. Arsenic-transformed malignant prostate epithelia can convert noncontiguous normal stem cells into an oncogenic phenotype. Environ Health Perspect. 2012; 120(6):865-871.
43. Xie L, Hu DP, Hu WY, Yang J, Prins GS. Arsenic dysregulates differentiation and induces tumorigenesis through accumulation of SQSTM1/p62 in prostate stem/progenitor cells. Central Society for Clinical and Translational Research, Chicago, IL, April 23-25, 2015.