Expression of estrogen receptor beta in the fetal, neonatal, and prepubertal human prostate

Prostate

Volumn 52, Issue 1, 2002, Pages 69-81

  Adams, Jason Y ^a   Leav, Irwin ^a,b,c,e   Lau, Kin Mang ^b   Ho, Shuk Mei ^b   Pflueger, Solveig M V ^d  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

^d BAYSTATE MEDICAL CENTER   (United States)

^e Division of Urology   (United States)

Author keywords

Estrogen receptor beta; Human fetal; Neonatal; Prepubertal prostate

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; ANDROGEN RECEPTOR; CYTOKERATIN; ESTROGEN RECEPTOR BETA; KI 67 ANTIGEN; PROSTATE SPECIFIC ANTIGEN;

ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CHILD; EPITHELIUM CELL; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MALE; NEWBORN; PARACRINE SIGNALING; POSTNATAL DEVELOPMENT; PREPUBERTY; PRIORITY JOURNAL; PROSTATE; PROSTATE EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL METAPLASIA; STROMA CELL;

CHILD; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FETAL DISEASES; GENE EXPRESSION; GESTATIONAL AGE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; INFANT, NEWBORN; KERATINS; KI-67 ANTIGEN; MALE; METAPLASIA; MOLECULAR WEIGHT; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0036604473     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.10103     Document Type: Article

References (57)

1. The endocrinology of prostate cancer
2. Androgen concentrations and their receptors in the periurethral region are higher than those of the subcapsular zone in benign prostatic hyperplasia (BPH)
3. The role of steroid hormones in prostate carcinogenesis
4. Neoplastic transformation of the prostate
5. Developmental estrogenization and prostatic neoplasia
6. Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses
7. Neonatal estrogen exposure alters the transforming growth factor-beta signaling system in the developing rat prostate and blocks the transient p21 (cip1/waf1) expression associated with epithelial differentiation
8. Estrogen receptor-beta: Implications for the prostate gland
9. Estrogen receptor β in prostate cancer: Brake pedal or accelerator?
10. The effect of castration, of oestrogen and of androgen injections on serum phosphatases in metastatic carcinoma of the prostate
11. Ultrastructural and biochemical expressions of divergent differentiation in prostates of castrated dogs treated with estrogen and androgen
12. Effect of the addition of estrogen to medical castration on prostatic size, symptoms, histology, and serum prostate specific antigen in 4 men with benign prostatic hypertrophy
13. Temporal and spatial factors in diethylstilbestrol-induced squamous metaplasia in the developing human prostate. II. Persistent changes after removal of diethylstilbestrol
14. Neonatal estrogen stimulates proliferation of periductal fibroblasts and alters the extracellular matrix composition in the rat prostate
15. Hormone levels in the foetal and neonatal prostate
16. Placental synthesis of steroid hormones
17. Sexual differentiation
18. Bipotentiality of response to sex hormones by the prostate of castrated or hypophysectomized dogs. Direct effects of estrogen
19. Multiple phenotypes of prostatic glandular cells in castrated dogs after individual or combined treatment with androgen and estrogen. Morphometric, ultrastructural, and cytochemical distinctions
20. Cloning of a novel receptor expressed in rat prostate and ovary
21. Identification and characterization of a novel human estrogen receptor
22. Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern
23. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
24. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites
25. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
26. Tissue distribution of estrogen receptors alpha (ER-alpha) and beta (ER-beta) mRNA in the midgestational human fetus
27. Immunocytochemical localization of estrogen receptors alpha and beta in the human reproductive organs
28. Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma
29. Immunohistochemical localization of transforming growth factor-alpha and transforming growth factor-beta during early human fetal prostate development
30. Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: Regulation by methylation and involvement in growth regulation
31. The proliferative function of basal cells in the normal and hyperplastic human prostate
32. Leydig cells and prostatic proliferation and secretion in the foetus and neonate in normal and complicated pregnancy
33. Testosterone formation and metabolism during male sexual differentiation in the human embryo
34. Stromal-epithelial interactions and heterogeneity of proliferative activity within the prostate
35. Growth factors as mediators of androgen action during male urogenital development
36. Androgens induce the expression of vascular endothelial growth factor in human fetal prostatic fibroblasts
37. Androgen receptor expression in prostatic dysplasia (prostatic intraepithelial neoplasia) in the human prostate: An immunohistochemical and in situ hybridization study
38. Identification of intermediate cell types by keratin expression in the developing human prostate
39. Analysis of the promoter of the human prostatic acid phosphatase gene
40. Cloning and analysis of the promoter activity of the human prostatic acid phosphatase gene
41. The promoter of the prostate-specific antigen gene contains a functional androgen responsive element
42. Cooperative assembly of androgen receptor into a nucleoprotein complex that regulates the prostate-specific antigen enhancer
43. Prostate stem cell compartments: Expression of the cell cycle inhibitor p27 Kip1 in normal, hyperplastic, and neoplastic cells
44. Demonstration of intermediate cells during human prostate epithelial differentiation in situ and in vitro using triple-staining confocal scanning microscopy
45. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
46. Expression of wild-type estrogen receptor beta and variant isoforms in human breast cancer
47. Cloning and characterization of human estrogen receptor beta isoforms
48. Molecular cloning and characterization of human estrogen receptor betacx: A potential inhibitor of estrogen action in human
49. A novel isoform of rat estrogen receptor beta with 18 amino acid insertion in the ligand binding domain as a putative dominant negative regular of estrogen action
50. Neonatal estrogen exposure upregulates estrogen receptor α expression in the developing and adult rat prostate lobes
51. Evidence that epithelial and mesenchymal estrogen receptor-alpha mediates effects of estrogen on prostatic epithelium
52. The role of estrogen receptor, androgen receptor and growth factors in diethylstilbestrol-induced programming of prostate differentiation
53. Induction of benign prostatic hyperplasia in intact dogs by near physiological levels of 5-α dihydrotestosterone and 17-β estradiol
54. Sex hormone-induced prostatic carcinogenesis in the noble rat: The role of insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in the development of prostate cancer
55. Androgen supported, estrogen-enhanced epithelial proliferation in the prostates of intact Noble rats
56. The metaplastic effects of estrogen on mouse prostate epithelium: Proliferation of cells with basal cell phenotype