The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes

Journal of Steroid Biochemistry and Molecular Biology

Volumn 127, Issue 1-2, 2011, Pages 9-15

  Li, Xia ^a   Ycaza, John ^a   Blumberg, Bruce ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adipogenesis; Endocrine disrupter; Obesogen; PPAR ; TBT; Tributyltin

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR; ROSIGLITAZONE; TRIACYLGLYCEROL; TRIBUTYLTIN CHLORIDE;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG HALF LIFE; GENE EXPRESSION; LIGAND BINDING; MARKER GENE; MOUSE; NONHUMAN;

3T3 CELLS; ADIPOGENESIS; ANILIDES; ANIMALS; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; MICE; PPAR GAMMA; THIAZOLIDINEDIONES; TRIALKYLTIN COMPOUNDS; TRIGLYCERIDES;

MURINAE;

EID: 80051818171     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2011.03.012     Document Type: Article

References (29)

1. F. Grun, and B. Blumberg Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling Endocrinology 147 6 Suppl. 2006 S50 S55
2. B. Blumberg Obesogens, stem cells and the maternal programming of obesity J. Dev. Origins Health Dis. FirstView 2010 1 6
3. F. Grun, and B. Blumberg Endocrine disrupters as obesogens Mol. Cell. Endocrinol. 304 1-2 2009 19 29
4. F. Grun, and B. Blumberg Minireview: the case for obesogens Mol. Endocrinol. 23 8 2009 1127 1134
5. A. Janesick, and B. Blumberg The role of environmental obesogens in the obesity epidemic R.H. Lustig, Obesity Before Birth 2011 Springer USA 383 399
6. A. Janesick, B. Blumberg, Adipocytes as target cells for endocrine disruption, in: E. Diamanti-Kandarakis, A.C. Gore (Eds.), Endocrine Disrupters and Puberty, Humana Press/Springer, New York, NY, in press.
7. A. Janesick, and B. Blumberg PPARg as the target of obesogens Journal of Steroid Biochemistry and Molecular Biology 127 2011 pp. 8-5
8. F. Grun, H. Watanabe, Z. Zamanian, L. Maeda, K. Arima, R. Cubacha, D.M. Gardiner, J. Kanno, T. Iguchi, and B. Blumberg Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates Mol. Endocrinol. 20 9 2006 2141 2155 (Pubitemid 44286710)
9. T. Kanayama, N. Kobayashi, S. Mamiya, T. Nakanishi, and J. Nishikawa Organotin compounds promote adipocyte differentiation as agonists of the peroxisome proliferator-activated receptor gamma/retinoid X receptor pathway Mol. Pharmacol. 67 3 2005 766 774 (Pubitemid 40365324)
10. S. Kirchner, T. Kieu, C. Chow, S. Casey, and B. Blumberg Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes Mol. Endocrinol. 24 3 2010 526 539
11. M. Carfi, C. Croera, D. Ferrario, V. Campi, G. Bowe, R. Pieters, and L. Gribaldo TBTC induces adipocyte differentiation in human bone marrow long term culture Toxicology 249 1 2008 11 18
12. E.D. Rosen, and O.A. MacDougald Adipocyte differentiation from the inside out Nat. Rev. Mol. Cell. Biol. 7 12 2006 885 896 (Pubitemid 44871415)
13. H. Inadera, and A. Shimomura Environmental chemical tributyltin augments adipocyte differentiation Toxicol. Lett. 159 3 2005 226 234 (Pubitemid 41501589)
14. H.M. Wright, C.B. Clish, T. Mikami, S. Hauser, K. Yanagi, R. Hiramatsu, C.N. Serhan, and B.M. Spiegelman A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation J. Biol. Chem. 275 3 2000 1873 1877 (Pubitemid 30060811)
15. C.J. Walkey, and B.M. Spiegelman A functional peroxisome proliferator-activated receptor-gamma ligand-binding domain is not required for adipogenesis J. Biol. Chem. 283 36 2008 24290 24294
16. P. Tontonoz, and B.M. Spiegelman Fat and beyond: the diverse biology of PPARgamma Annu. Rev. Biochem. 77 2008 289 312
17. A. IJpenberg, N.S. Tan, L. Gelman, S. Kersten, J. Seydoux, J. Xu, D. Metzger, L. Canaple, P. Chambon, W. Wahli, and B. Desvergne In vivo activation of PPAR target genes by RXR homodimers EMBO J. 23 10 2004 2083 2091 (Pubitemid 38737735)
18. I.G. Schulman, G. Shao, and R.A. Heyman Transactivation by retinoid X receptor-peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimers: intermolecular synergy requires only the PPARgamma hormone-dependent activation function Mol. Cell. Biol. 18 6 1998 3483 3494 (Pubitemid 28240520)
19. T. Perlmann, K. Umesono, P.N. Rangarajan, B.M. Forman, and R.M. Evans Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors Mol. Endocrinol. 10 8 1996 958 966 (Pubitemid 26268878)
20. B.M. Forman, K. Umesono, J. Chen, and R.M. Evans Unique response pathways are established by allosteric interactions among nuclear hormone receptors Cell 81 4 1995 541 550
21. T.M. Willson, P.J. Brown, D.D. Sternbach, and B.R. Henke The PPARs: from orphan receptors to drug discovery J. Med. Chem. 43 4 2000 527 550 (Pubitemid 30127149)
22. G. Lee, F. Elwood, J. McNally, J. Weiszmann, M. Lindstrom, K. Amaral, M. Nakamura, S. Miao, P. Cao, R.M. Learned, J.L. Chen, and Y. Li T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities J. Biol. Chem. 277 22 2002 19649 19657 (Pubitemid 34967479)
23. S.S Choi, B.Y. Cha, Y.S. Lee, T. Yonezawa, T. Teruya, K. Nagai, and J.T. Woo Magnolol enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells Life Sci. 84 25-26 2009 908 914
24. E.E. Kershaw, M. Schupp, H.P. Guan, N.P. Gardner, M.A. Lazar, and J.S. Flier PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo Am. J. Physiol. Endocrinol. Metab. 293 6 2007 E1736 E1745
25. Y. Xiao, T. Yuan, W. Yao, and K. Liao 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-gamma- dependent and mediated by the caspase-3-dependent apoptotic pathway FEBS J. 277 3 2010 687 696
26. J.Y. Yang, M.A. Della-Fera, S. Rayalam, H.J. Park, S. Ambati, D.B. Hausman, D.L. Hartzell, and C.A. Baile Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail J. Nutr. Biochem. 20 7 2009 537 543
27. Y. Hiromori, J. Nishikawa, I. Yoshida, H. Nagase, and T. Nakanishi Structure-dependent activation of peroxisome proliferator-activated receptor (PPAR) gamma by organotin compounds Chem. Biol. Interact. 180 2 2009 238 244
28. A. le Maire, M. Grimaldi, D. Roecklin, S. Dagnino, V. Vivat-Hannah, P. Balaguer, and W. Bourguet Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors EMBO Rep. 10 4 2009 367 373
29. M.R. Milnes, A. Garcia, E. Grossman, F. Grun, J. Shiotsugu, M.M. Tabb, Y. Kawashima, Y. Katsu, H. Watanabe, T. Iguchi, and B. Blumberg Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species Environ. Health Perspect. 116 7 2008 880 885 (Pubitemid 351943894)