Serine protease activation essential for endothelial-mesenchymal transition in vascular calcification

Circulation Research

Volumn 117, Issue 9, 2015, Pages 758-769

  Yao, Jiayi ^a,c   Guihard, Pierre J ^a   Blazquez Medela, Ana M ^a   Guo, Yina ^a   Moon, Jeremiah H ^a   Jumabay, Medet ^a   Boström, Kristina I ^a,b   Yao, Yucheng ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

endothelium; matrix Gla protein; phenotype; serine proteases; vascular calcification

Indexed keywords

ACID PROTEIN; MATRIX GAMMA CARBOXYGLUTAMIC ACID PROTEIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; KALLIKREIN; MATRIX GLA PROTEIN; NUCLEAR PROTEIN; PANCREATIC ELASTASE; SCLEROPROTEIN; SOX2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX; TWIST RELATED PROTEIN 1; TWIST1 PROTEIN, MOUSE;

AORTA; ARTICLE; BLOOD VESSEL CALCIFICATION; CELL TRANSFORMATION; CONTROLLED STUDY; ENDOTHELIAL MESENCHYMAL TRANSITION; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE DELETION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; ANIMAL; C57BL MOUSE; CALCINOSIS; CELL CULTURE; GENE EXPRESSION PROFILING; GENETICS; IMMUNOBLOTTING; KNOCKOUT MOUSE; MESODERM; METABOLISM; PATHOLOGY; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SCANNING ELECTRON MICROSCOPY; TRANSGENIC MOUSE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM;

ANIMALS; CALCINOSIS; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION PROFILING; HUMANS; IMMUNOBLOTTING; KALLIKREINS; MESODERM; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NUCLEAR PROTEINS; PANCREATIC ELASTASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SERINE ENDOPEPTIDASES; SOXB1 TRANSCRIPTION FACTORS; TWIST-RELATED PROTEIN 1;

EID: 84943630698     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.306751     Document Type: Article

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