Altered cGMP Dynamics at the Plasma Membrane Contribute to Diarrhea in Ulcerative Colitis

American Journal of Pathology

Volumn 185, Issue 10, 2015, Pages 2790-2804

  Arora, Kavisha ^a,b   Sinha, Chandrima ^b   Zhang, Weiqiang ^b   Moon, Chang Suk ^a,b   Ren, Aixia ^b   Yarlagadda, Sunitha ^a,b   Dostmann, Wolfgang R ^c   Adebiyi, Adebowale ^b   Haberman, Yael ^a   Denson, Lee A ^a   Wang, Xusheng ^d   Naren, Anjaparavanda P ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF VERMONT   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL BLOCKING AGENT; CYCLIC GMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR INH 172; INDUCIBLE NITRIC OXIDE SYNTHASE; LYSINE DERIVATIVE; LYSINE DIHYDROCHLORIDE; MEMBRANE PROTEIN; NITRIC OXIDE; SCAFFOLD PROTEIN; SODIUM POTASSIUM EXCHANGER REGULATORY FACTOR 2; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG; ZAPRINAST; PHOSPHOPROTEIN; SODIUM-HYDROGEN EXCHANGER REGULATORY FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; DIARRHEA; ENZYME ACTIVITY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM; MACROMOLECULE; MALE; MOUSE; MYRISTYLATION; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; ULCERATIVE COLITIS; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL MEMBRANE; CELLS, CULTURED; COLITIS, ULCERATIVE; CYCLIC GMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIARRHEA; DISEASE MODELS, ANIMAL; HUMANS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER;

EID: 84943609180     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.06.007     Document Type: Article

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