A chemokine receptor CXCR2 macromolecular complex regulates neutrophil functions in inflammatory diseases

Journal of Biological Chemistry

Volumn 287, Issue 8, 2012, Pages 5744-5755

  Wu, Yanning ^a   Wang, Shuo ^a   Farooq, Shukkur M ^a,d   Castelvetere, Marcello P ^a   Hou, Yuning ^a   Gao, Ji Liang ^b   Navarro, Javier V ^c   Oupicky, David ^a   Sun, Fei ^a   Li, Chunying ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR FUNCTION; CHEMOKINE RECEPTORS; CO-IMMUNOPRECIPITATIONS; CYSTIC FIBROSIS; ESSENTIAL COMPONENT; HOST DEFENSE; HUMAN DISEASE; IN-VITRO; INFLAMMATORY BOWEL DISEASE; INFLAMMATORY DISEASE; INTRACELLULAR CALCIUM MOBILIZATION; ISCHEMIA-REPERFUSION INJURY; MACROMOLECULAR COMPLEXES; MULTI-PROTEIN COMPLEX; NEUTROPHIL FUNCTIONS; PATHOPHYSIOLOGY; PHOSPHOLIPASE C; PROGRESSIVE DAMAGE; SCAFFOLD PROTEIN; SIGNALING COMPLEX; SIGNALING MOLECULES; THERAPEUTIC STRATEGY;

BIOCHEMISTRY; DISEASES; PATHOLOGY; PLANTS (BOTANY); TISSUE;

MACROMOLECULES;

CALCIUM; CHEMOKINE RECEPTOR CXCR2; PDZ PROTEIN; PHOSPHOLIPASE C BETA2; SCAFFOLD PROTEIN; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATORY DISEASE; LEUKOCYTE FUNCTION; MACROMOLECULE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

AMINO ACID MOTIFS; ANIMALS; CALCIUM SIGNALING; CHEMOTAXIS, LEUKOCYTE; EPITHELIAL CELLS; HEK293 CELLS; HL-60 CELLS; HUMANS; INFLAMMATION; INTRACELLULAR SPACE; MICE; NEUTROPHILS; PDZ DOMAINS; PEPTIDE FRAGMENTS; PHOSPHOLIPASE C BETA; PHOSPHOPROTEINS; RECEPTORS, INTERLEUKIN-8B; SODIUM-HYDROGEN ANTIPORTER; SUBSTRATE SPECIFICITY;

EID: 84863158649     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.315762     Document Type: Article

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