-
1
-
-
33751112510
-
IFN-γ and TNF-α regulate human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line C2BBe1
-
Amin MR, Malakooti J, Sandoval R, Dudeja PK, Ramaswamy K. IFN-γ and TNF-α regulate human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line C2BBe1. Am J Physiol Cell Physiol 291: C887-C896, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Amin, M.R.1
Malakooti, J.2
Sandoval, R.3
Dudeja, P.K.4
Ramaswamy, K.5
-
2
-
-
9144265423
-
Mechanisms of diarrhea in the interleukin-2-deficient mouse model of colonic inflammation
-
Barmeyer C, Harren M, Schmitz H, Heinzel-Pleines U, Mankertz J, Seidler U, Horak I, Wiedenmann B, Fromm M, Schulzke JD. Mechanisms of diarrhea in the interleukin-2-deficient mouse model of colonic inflammation. Am J Physiol Gastrointest Liver Physiol 286: G244-G252, 2004.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.286
-
-
Barmeyer, C.1
Harren, M.2
Schmitz, H.3
Heinzel-Pleines, U.4
Mankertz, J.5
Seidler, U.6
Horak, I.7
Wiedenmann, B.8
Fromm, M.9
Schulzke, J.D.10
-
3
-
-
33751114964
-
IL-10 protects mouse intestinal epithelial cells from Fas-induced apoptosis via modulating Fas expression and altering caspase-8 and FLIP expression
-
Bharhani MS, Borojevic R, Basak S, Ho E, Zhou P, Croitoru K. IL-10 protects mouse intestinal epithelial cells from Fas-induced apoptosis via modulating Fas expression and altering caspase-8 and FLIP expression. Am J Physiol Gastrointest Liver Physiol 291: G820-G829, 2006.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.291
-
-
Bharhani, M.S.1
Borojevic, R.2
Basak, S.3
Ho, E.4
Zhou, P.5
Croitoru, K.6
-
4
-
-
67249090773
-
Mechanisms of diarrhea in inflammatory bowel diseases
-
Binder HJ. Mechanisms of diarrhea in inflammatory bowel diseases. Ann NY Acad Sci 1165: 285-293, 2009.
-
(2009)
Ann NY Acad Sci
, vol.1165
, pp. 285-293
-
-
Binder, H.J.1
-
5
-
-
33749428028
-
Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo
-
Clayburgh DR, Musch MW, Leitges M, Fu YX, Turner JR. Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo. J Clin Invest 116: 2682-2694, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 2682-2694
-
-
Clayburgh, D.R.1
Musch, M.W.2
Leitges, M.3
Fu, Y.X.4
Turner, J.R.5
-
6
-
-
0028101467
-
IL-4 directly modulates function of a model human intestinal epithelium
-
Colgan SP, Resnick MB, Parkos CA, Delp-Archer C, McGuirk D, Bacarra AE, Weller PF, Madara JL. IL-4 directly modulates function of a model human intestinal epithelium. J Immunol 153: 2122-2129, 1994.
-
(1994)
J Immunol
, vol.153
, pp. 2122-2129
-
-
Colgan, S.P.1
Resnick, M.B.2
Parkos, C.A.3
Delp-Archer, C.4
McGuirk, D.5
Bacarra, A.E.6
Weller, P.F.7
Madara, J.L.8
-
8
-
-
0030018186
-
+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice
-
+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice. J Exp Med 184: 241-251, 1996.
-
(1996)
J Exp Med
, vol.184
, pp. 241-251
-
-
Davidson, N.J.1
Leach, M.W.2
Fort, M.M.3
Thompson-Snipes, L.4
Kuhn, R.5
Muller, W.6
Berg, D.J.7
Rennick, D.M.8
-
9
-
-
33646801637
-
Regulation of apoptosis during homeostasis and disease in the intestinal epithelium
-
Edelblum KL, Yan F, Yamaoka T, Polk DB. Regulation of apoptosis during homeostasis and disease in the intestinal epithelium. Inflamm Bowel Dis 12: 413-424, 2006.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 413-424
-
-
Edelblum, K.L.1
Yan, F.2
Yamaoka, T.3
Polk, D.B.4
-
10
-
-
33750374367
-
+ efflux prevents mitochondrial dysfunction and suppresses caspase-3-, apoptosisinducing factor-, and endonuclease G-mediated constitutive apoptosis in human neutrophils
-
+ efflux prevents mitochondrial dysfunction and suppresses caspase-3-, apoptosisinducing factor-, and endonuclease G-mediated constitutive apoptosis in human neutrophils. Cell Signal 18: 2302-2313, 2006.
-
(2006)
Cell Signal
, vol.18
, pp. 2302-2313
-
-
El, K.D.1
Jozsef, L.2
Khreiss, T.3
Filep, J.G.4
-
11
-
-
79952462235
-
New therapeutic targets in ulcerative colitis: The importance of ion transporters in the human colon
-
Farkas K, Yeruva S, Rakonczay Z Jr, Ludolph L, Molnar T, Nagy F, Szepes Z, Schnur A, Wittmann T, Hubricht J, Riederer B, Venglovecz V, Lazar G, Kiraly M, Zsembery A, Varga G, Seidler U, Hegyi P. New therapeutic targets in ulcerative colitis: the importance of ion transporters in the human colon. Inflamm Bowel Dis 17: 884-898, 2011.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 884-898
-
-
Farkas, K.1
Yeruva, S.2
Rakonczay Jr., Z.3
Ludolph, L.4
Molnar, T.5
Nagy, F.6
Szepes, Z.7
Schnur, A.8
Wittmann, T.9
Hubricht, J.10
Riederer, B.11
Venglovecz, V.12
Lazar, G.13
Kiraly, M.14
Zsembery, A.15
Varga, G.16
Seidler, U.17
Hegyi, P.18
-
12
-
-
67650225283
-
Gene expression patterns in experimental colitis in IL-10-deficient mice
-
Hansen JJ, Holt L, Sartor RB. Gene expression patterns in experimental colitis in IL-10-deficient mice. Inflamm Bowel Dis 15: 890-899, 2009.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 890-899
-
-
Hansen, J.J.1
Holt, L.2
Sartor, R.B.3
-
13
-
-
3242658157
-
+ exchange isoform activities by enteropathogenic E. coli in human intestinal epithelial cells
-
+ exchange isoform activities by enteropathogenic E. coli in human intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 287: G370-G378, 2004.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Hecht, G.1
Hodges, K.2
Gill, R.K.3
Kear, F.4
Tyagi, S.5
Malakooti, J.6
Ramaswamy, K.7
Dudeja, P.K.8
-
14
-
-
0034958935
-
Coordinate upregulation of interleukin- 8 and growth-related gene product-α is present in the colonic mucosa of inflammatory bowel
-
Imada A, Ina K, Shimada M, Yokoyama T, Yokoyama Y, Nishio Y, Yamaguchi T, Ando T, Kusugami K. Coordinate upregulation of interleukin- 8 and growth-related gene product-α is present in the colonic mucosa of inflammatory bowel. Scand J Gastroenterol 36: 854-864, 2001.
-
(2001)
Scand J Gastroenterol
, vol.36
, pp. 854-864
-
-
Imada, A.1
Ina, K.2
Shimada, M.3
Yokoyama, T.4
Yokoyama, Y.5
Nishio, Y.6
Yamaguchi, T.7
Ando, T.8
Kusugami, K.9
-
15
-
-
77249150521
-
Endoplasmic reticulum stress and intestinal inflammation
-
Kaser A, Blumberg RS. Endoplasmic reticulum stress and intestinal inflammation. Mucosal Immunol 3: 11-16, 2010.
-
(2010)
Mucosal Immunol
, vol.3
, pp. 11-16
-
-
Kaser, A.1
Blumberg, R.S.2
-
16
-
-
69249100598
-
Changes in mucosal homeostasis predispose NHE3 knockout mice to increased susceptibility to DSS-induced epithelial injury
-
Kiela PR, Laubitz D, Larmonier CB, Midura-Kiela MT, Lipko MA, Janikashvili N, Bai A, Thurston R, Ghishan FK. Changes in mucosal homeostasis predispose NHE3 knockout mice to increased susceptibility to DSS-induced epithelial injury. Gastroenterology 137: 965-975, 2009.
-
(2009)
Gastroenterology
, vol.137
, pp. 965-975
-
-
Kiela, P.R.1
Laubitz, D.2
Larmonier, C.B.3
Midura-Kiela, M.T.4
Lipko, M.A.5
Janikashvili, N.6
Bai, A.7
Thurston, R.8
Ghishan, F.K.9
-
17
-
-
15244359179
-
Effects of Boswellia serrata in mouse models of chemically induced colitis
-
Kiela PR, Midura AJ, Kuscuoglu N, Jolad SD, Solyom AM, Besselsen DG, Timmermann BN, Ghishan FK. Effects of Boswellia serrata in mouse models of chemically induced colitis. Am J Physiol Gastrointest Liver Physiol 288: G798-G808, 2005.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
-
-
Kiela, P.R.1
Midura, A.J.2
Kuscuoglu, N.3
Jolad, S.D.4
Solyom, A.M.5
Besselsen, D.G.6
Timmermann, B.N.7
Ghishan, F.K.8
-
18
-
-
51149084376
-
Colonic gene expression profile in NHE3-deficient mice: Evidence for spontaneous distal colitis
-
Laubitz D, Larmonier CB, Bai A, Midura-Kiela MT, Lipko MA, Thurston RD, Kiela PR, Ghishan FK. Colonic gene expression profile in NHE3-deficient mice: evidence for spontaneous distal colitis. Am J Physiol Gastrointest Liver Physiol 295: G63-G77, 2008.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.295
-
-
Laubitz, D.1
Larmonier, C.B.2
Bai, A.3
Midura-Kiela, M.T.4
Lipko, M.A.5
Thurston, R.D.6
Kiela, P.R.7
Ghishan, F.K.8
-
19
-
-
0024553788
-
Interferon-γ directly affects barrier function of cultured intestinal epithelial monolayers
-
Madara JL, Stafford J. Interferon-γ directly affects barrier function of cultured intestinal epithelial monolayers. J Clin Invest 83: 724-727, 1989.
-
(1989)
J Clin Invest
, vol.83
, pp. 724-727
-
-
Madara, J.L.1
Stafford, J.2
-
20
-
-
0031011849
-
Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion
-
Madsen KL, Lewis SA, Tavernini MM, Hibbard J, Fedorak RN. Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion. Gastroenterology 113: 151-159, 1997.
-
(1997)
Gastroenterology
, vol.113
, pp. 151-159
-
-
Madsen, K.L.1
Lewis, S.A.2
Tavernini, M.M.3
Hibbard, J.4
Fedorak, R.N.5
-
21
-
-
61949259407
-
Molecular bases of impaired water and ion movements in inflammatory bowel diseases
-
Martinez-Augustin O, Romero-Calvo I, Suarez MD, Zarzuelo A, de Medina FS. Molecular bases of impaired water and ion movements in inflammatory bowel diseases. Inflamm Bowel Dis 15: 114-127, 2009.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 114-127
-
-
Martinez-Augustin, O.1
Romero-Calvo, I.2
Suarez, M.D.3
Zarzuelo, A.4
de Medina, F.S.5
-
22
-
-
77956652125
-
Animal models of IBD: Linkage to human disease
-
Mizoguchi A, Mizoguchi E. Animal models of IBD: linkage to human disease. Curr Opin Pharmacol 10: 578-587, 2010.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 578-587
-
-
Mizoguchi, A.1
Mizoguchi, E.2
-
23
-
-
34347212526
-
+ deprivation results in apoptotic cell death in human epithelial HeLa cells
-
+ deprivation results in apoptotic cell death in human epithelial HeLa cells. J Physiol Sci 56: 335-339, 2006.
-
(2006)
J Physiol Sci
, vol.56
, pp. 335-339
-
-
Nukui, M.1
Shimizu, T.2
Okada, Y.3
-
24
-
-
14044250862
-
IL-10 gene-deficient mice lack TGF- /Smad signaling and fail to inhibit proinflammatory gene expression in intestinal epithelial cells after the colonization with colitogenic Enterococcus faecalis
-
Ruiz PA, Shkoda A, Kim SC, Sartor RB, Haller D. IL-10 gene-deficient mice lack TGF- /Smad signaling and fail to inhibit proinflammatory gene expression in intestinal epithelial cells after the colonization with colitogenic Enterococcus faecalis. J Immunol 174: 2990-2999, 2005.
-
(2005)
J Immunol
, vol.174
, pp. 2990-2999
-
-
Ruiz, P.A.1
Shkoda, A.2
Kim, S.C.3
Sartor, R.B.4
Haller, D.5
-
25
-
-
0000418018
-
Tumor necrosis factor-α (TNFα) regulates the epithelial barrier in the human intestinal cell line HT-29/B6
-
Schmitz H, Fromm M, Bentzel CJ, Scholz P, Detjen K, Mankertz J, Bode H, Epple HJ, Riecken EO, Schulzke JD. Tumor necrosis factor-α (TNFα) regulates the epithelial barrier in the human intestinal cell line HT-29/B6. J Cell Sci 112: 137-146, 1999.
-
(1999)
J Cell Sci
, vol.112
, pp. 137-146
-
-
Schmitz, H.1
Fromm, M.2
Bentzel, C.J.3
Scholz, P.4
Detjen, K.5
Mankertz, J.6
Bode, H.7
Epple, H.J.8
Riecken, E.O.9
Schulzke, J.D.10
-
26
-
-
0038851888
-
+ exchanger
-
+ exchanger. Nat Genet 19: 282-285, 1998.
-
(1998)
Nat Genet
, vol.19
, pp. 282-285
-
-
Schultheis, P.J.1
Clarke, L.L.2
Meneton, P.3
Miller, M.L.4
Soleimani, M.5
Gawenis, L.R.6
Riddle, T.M.7
Duffy, J.J.8
Doetschman, T.9
Wang, T.10
Giebisch, G.11
Aronson, P.S.12
Lorenz, J.N.13
Shull, G.E.14
-
27
-
-
33748996522
-
Molecular mechanisms of disturbed electrolyte transport in intestinal inflammation
-
Seidler U, Lenzen H, Cinar A, Tessema T, Bleich A, Riederer B. Molecular mechanisms of disturbed electrolyte transport in intestinal inflammation. Ann NY Acad Sci 1072: 262-275, 2006.
-
(2006)
Ann NY Acad Sci
, vol.1072
, pp. 262-275
-
-
Seidler, U.1
Lenzen, H.2
Cinar, A.3
Tessema, T.4
Bleich, A.5
Riederer, B.6
-
28
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
Sellon RK, Tonkonogy S, Schultz M, Dieleman LA, Grenther W, Balish E, Rennick DM, Sartor RB. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 66: 5224-5231, 1998.
-
(1998)
Infect Immun
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
Dieleman, L.A.4
Grenther, W.5
Balish, E.6
Rennick, D.M.7
Sartor, R.B.8
-
29
-
-
33846234333
-
Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: Impact on chronic inflammation
-
Shkoda A, Ruiz PA, Daniel H, Kim SC, Rogler G, Sartor RB, Haller D. Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation. Gastroenterology 132: 190-207, 2007.
-
(2007)
Gastroenterology
, vol.132
, pp. 190-207
-
-
Shkoda, A.1
Ruiz, P.A.2
Daniel, H.3
Kim, S.C.4
Rogler, G.5
Sartor, R.B.6
Haller, D.7
-
30
-
-
66449131072
-
Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: Potential contributors to IBD-associated diarrhea
-
Sullivan S, Alex P, Dassopoulos T, Zachos NC, Iacobuzio-Donahue C, Donowitz M, Brant SR, Cuffari C, Harris ML, Datta LW, Conklin L, Chen Y, Li X. Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: potential contributors to IBD-associated diarrhea. Inflamm Bowel Dis 15: 261-274, 2009.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 261-274
-
-
Sullivan, S.1
Alex, P.2
Dassopoulos, T.3
Zachos, N.C.4
Iacobuzio-Donahue, C.5
Donowitz, M.6
Brant, S.R.7
Cuffari, C.8
Harris, M.L.9
Datta, L.W.10
Conklin, L.11
Chen, Y.12
Li, X.13
-
31
-
-
0036314767
-
Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in rats
-
Vetuschi A, Latella G, Sferra R, Caprilli R, Gaudio E. Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci 47: 1447-1457, 2002.
-
(2002)
Dig Dis Sci
, vol.47
, pp. 1447-1457
-
-
Vetuschi, A.1
Latella, G.2
Sferra, R.3
Caprilli, R.4
Gaudio, E.5
-
32
-
-
2242492673
-
+ exchanger knockout model of congenital diarrhea
-
+ exchanger knockout model of congenital diarrhea. J Biol Chem 277: 49036-49046, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 49036-49046
-
-
Woo, A.L.1
Gildea, L.A.2
Tack, L.M.3
Miller, M.L.4
Spicer, Z.5
Millhorn, D.E.6
Finkelman, F.D.7
Hassett, D.J.8
Shull, G.E.9
-
33
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 116: 1310-1316, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
Murphy, E.11
Sathe, M.12
Cua, D.J.13
Kastelein, R.A.14
Rennick, D.15
-
34
-
-
77953699752
-
+ exchanger isoform 3 expression and localization, but decreased NHE3 function indicate regulatory sodium transport defect in ulcerative colitis
-
+ exchanger isoform 3 expression and localization, but decreased NHE3 function indicate regulatory sodium transport defect in ulcerative colitis. Inflamm Bowel Dis 16: 1149-1161, 2010.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 1149-1161
-
-
Yeruva, S.1
Farkas, K.2
Hubricht, J.3
Rode, K.4
Riederer, B.5
Bachmann, O.6
Cinar, A.7
Rakonczay, Z.8
Molnar, T.9
Nagy, F.10
Wedemeyer, J.11
Manns, M.12
Raddatz, D.13
Musch, M.W.14
Chang, E.B.15
Hegyi, P.16
Seidler, U.17
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