-
1
-
-
0028968622
-
Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-Tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class
-
Buchdunger E, Zimmermann J, Mett H, Meyer T, Muller M, Regenass U, et al. Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-Tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci USA 1995; 92: 2558-2562
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2558-2562
-
-
Buchdunger, E.1
Zimmermann, J.2
Mett, H.3
Meyer, T.4
Muller, M.5
Regenass, U.6
-
2
-
-
33745085275
-
OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): Reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib
-
White DL, Saunders VA, Dang P, Engler J, Zannettino AC, Cambareri AC, et al. OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. Blood 2006; 108: 697-704
-
(2006)
Blood
, vol.108
, pp. 697-704
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
Engler, J.4
Zannettino, A.C.5
Cambareri, A.C.6
-
3
-
-
37049028176
-
Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: Higher doses of imatinib may overcome the negative impact of low OCT-1 activity
-
White DL, Saunders VA, Dang P, Engler J, Venables A, Zrim S, et al. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity. Blood 2007; 110: 4064-4072
-
(2007)
Blood
, vol.110
, pp. 4064-4072
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
Engler, J.4
Venables, A.5
Zrim, S.6
-
4
-
-
77949767505
-
International Randomized Study of Interferon Vs STI571 (IRIS) 8-Year Follow up: Sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib
-
Deininger M, O'Brien SG, Guilhot F, Goldman JM, Hochhaus A, Hughes TP, et al. International Randomized Study of Interferon Vs STI571 (IRIS) 8-Year Follow up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib. ASH Annu Meet Abstr 2009; 114: 1126
-
(2009)
ASH Annu Meet Abstr
, vol.114
, pp. 1126
-
-
Deininger, M.1
O'Brien, S.G.2
Guilhot, F.3
Goldman, J.M.4
Hochhaus, A.5
Hughes, T.P.6
-
5
-
-
58149396984
-
European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor
-
Marin D, Milojkovic D, Olavarria E, Khorashad JS, de Lavallade H, Reid AG, et al. European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor. Blood 2008; 112: 4437-4444
-
(2008)
Blood
, vol.112
, pp. 4437-4444
-
-
Marin, D.1
Milojkovic, D.2
Olavarria, E.3
Khorashad, J.S.4
De Lavallade, H.5
Reid, A.G.6
-
6
-
-
79952081141
-
Front-line and salvage therapies with tyrosine kinase inhibitors and other treatments in chronic myeloid leukemia
-
Cortes J, Hochhaus A, Hughes T, Kantarjian H. Front-line and salvage therapies with tyrosine kinase inhibitors and other treatments in chronic myeloid leukemia. J Clin Oncol 2011; 29: 524-531
-
(2011)
J Clin Oncol
, vol.29
, pp. 524-531
-
-
Cortes, J.1
Hochhaus, A.2
Hughes, T.3
Kantarjian, H.4
-
7
-
-
0037438467
-
Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia
-
Kantarjian HM, Talpaz M, O'Brien S, Giles F, Garcia-Manero G, Faderl S, et al. Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia. Blood 2003; 101: 473-475
-
(2003)
Blood
, vol.101
, pp. 473-475
-
-
Kantarjian, H.M.1
Talpaz, M.2
O'Brien, S.3
Giles, F.4
Garcia-Manero, G.5
Faderl, S.6
-
8
-
-
23044433630
-
HOCT 1 and resistance to imatinib
-
Crossman LC, Druker BJ, Deininger MW, Pirmohamed M, Wang L, Clark RE. hOCT 1 and resistance to imatinib. Blood 2005; 106: 1133-1134
-
(2005)
Blood
, vol.106
, pp. 1133-1134
-
-
Crossman, L.C.1
Druker, B.J.2
Deininger, M.W.3
Pirmohamed, M.4
Wang, L.5
Clark, R.E.6
-
9
-
-
9444282642
-
Active transport of imatinib into and out of cells: Implications for drug resistance
-
Thomas J, Wang L, Clark RE, Pirmohamed M. Active transport of imatinib into and out of cells: implications for drug resistance. Blood 2004; 104: 3739-3745
-
(2004)
Blood
, vol.104
, pp. 3739-3745
-
-
Thomas, J.1
Wang, L.2
Clark, R.E.3
Pirmohamed, M.4
-
10
-
-
77954936879
-
Functional activity of the OCT-1 protein is predictive of long-Term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib
-
White DL, Dang P, Engler J, Frede A, Zrim S, Osborn M, et al. Functional activity of the OCT-1 protein is predictive of long-Term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib. J Clin Oncol 2010; 28: 2761-2767
-
(2010)
J Clin Oncol
, vol.28
, pp. 2761-2767
-
-
White, D.L.1
Dang, P.2
Engler, J.3
Frede, A.4
Zrim, S.5
Osborn, M.6
-
11
-
-
77952467377
-
Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib
-
Marin D, Bazeos A, Mahon FX, Eliasson L, Milojkovic D, Bua M, et al. Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib. J Clin Oncol 2010; 28: 2381-2388
-
(2010)
J Clin Oncol
, vol.28
, pp. 2381-2388
-
-
Marin, D.1
Bazeos, A.2
Mahon, F.X.3
Eliasson, L.4
Milojkovic, D.5
Bua, M.6
-
12
-
-
84859128208
-
Correlation between imatinib trough concentration and efficacy in Chinese chronic myelocytic leukemia patients
-
Zhong JS, Meng FY, Xu D, Zhou HS, Dai M. Correlation between imatinib trough concentration and efficacy in Chinese chronic myelocytic leukemia patients. Acta Haematol 2012; 127: 221-227
-
(2012)
Acta Haematol
, vol.127
, pp. 221-227
-
-
Zhong, J.S.1
Meng, F.Y.2
Xu, D.3
Zhou, H.S.4
Dai, M.5
-
13
-
-
84859649735
-
Pretherapeutic expression of the hOCT1 gene predicts a complete molecular response to imatinib mesylate in chronic-phase chronic myeloid leukemia
-
Nardinelli L, Sanabani SS, Didone A, Ferreira Pde B, Serpa M, Novaes MM, et al. Pretherapeutic expression of the hOCT1 gene predicts a complete molecular response to imatinib mesylate in chronic-phase chronic myeloid leukemia. Acta Haematol 2012; 127: 228-234
-
(2012)
Acta Haematol
, vol.127
, pp. 228-234
-
-
Nardinelli, L.1
Sanabani, S.S.2
Didone, A.3
Ferreira Pde, B.4
Serpa, M.5
Novaes, M.M.6
-
14
-
-
84872768729
-
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib
-
Gromicho M, Magalhaes M, Torres F, Dinis J, Fernandes AR, Rendeiro P, et al. Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib. Oncol Rep 2013; 29: 741-750
-
(2013)
Oncol Rep
, vol.29
, pp. 741-750
-
-
Gromicho, M.1
Magalhaes, M.2
Torres, F.3
Dinis, J.4
Fernandes, A.R.5
Rendeiro, P.6
-
15
-
-
49649092002
-
Interaction of imatinib with human organic ion carriers
-
Hu S, Franke RM, Filipski KK, Hu C, Orwick SJ, de Bruijn EA, et al. Interaction of imatinib with human organic ion carriers. Clin Cancer Res. 2008; 14: 3141-3148
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3141-3148
-
-
Hu, S.1
Franke, R.M.2
Filipski, K.K.3
Hu, C.4
Orwick, S.J.5
De Bruijn, E.A.6
-
16
-
-
84896713257
-
Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1
-
Nies AT, Schaeffeler E, van der Kuip H, Cascorbi I, Bruhn O, Kneba M, et al. Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1). Clin Cancer Res 2014; 20: 985-994
-
(2014)
Clin Cancer Res
, vol.20
, pp. 985-994
-
-
Nies, A.T.1
Schaeffeler, E.2
Van Der Kuip, H.3
Cascorbi, I.4
Bruhn, O.5
Kneba, M.6
-
17
-
-
34249943356
-
Polyspecific organic cation transporters: Structure, function, physiological roles, and biopharmaceutical implications
-
Koepsell H, Lips K, Volk C. Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications. Pharm Res 2007; 24: 1227-1251
-
(2007)
Pharm Res
, vol.24
, pp. 1227-1251
-
-
Koepsell, H.1
Lips, K.2
Volk, C.3
-
18
-
-
1242295185
-
The SLC22 drug transporter family
-
Koepsell H, Endou H. The SLC22 drug transporter family. Pflugers Archiv 2004; 447: 666-676
-
(2004)
Pflugers Archiv
, vol.447
, pp. 666-676
-
-
Koepsell, H.1
Endou, H.2
-
19
-
-
78149428500
-
OCT-1 activity measurement provides a superior imatinib response predictor than screening for singlenucleotide polymorphisms of OCT-1
-
White DL, Saunders VA, Dang P, Engler J, Hughes TP. OCT-1 activity measurement provides a superior imatinib response predictor than screening for singlenucleotide polymorphisms of OCT-1. Leukemia 2010; 24: 1962-1965
-
(2010)
Leukemia
, vol.24
, pp. 1962-1965
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
Engler, J.4
Hughes, T.P.5
-
20
-
-
84861454645
-
Classification of patients with chronic myeloid leukemia on basis of BCR-ABL transcript level at 3 months fails to identify patients with low organic cation transporter-1 activity destined to have poor imatinib response
-
White DL, Hughes TP. Classification of patients with chronic myeloid leukemia on basis of BCR-ABL transcript level at 3 months fails to identify patients with low organic cation transporter-1 activity destined to have poor imatinib response. J Clin Oncol 2012; 30: 1144-1145
-
(2012)
J Clin Oncol
, vol.30
, pp. 1144-1145
-
-
White, D.L.1
Hughes, T.P.2
-
21
-
-
38349193809
-
Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia
-
Wang L, Giannoudis A, Lane S, Williamson P, Pirmohamed M, Clark RE. Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. Clin Pharmacol Ther 2008; 83: 258-264
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 258-264
-
-
Wang, L.1
Giannoudis, A.2
Lane, S.3
Williamson, P.4
Pirmohamed, M.5
Clark, R.E.6
-
22
-
-
84873032664
-
The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-Treated chronic myeloid leukemia
-
Giannoudis A, Wang L, Jorgensen AL, Xinarianos G, Davies A, Pushpakom S, et al. The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-Treated chronic myeloid leukemia. Blood 2013; 121: 628-637
-
(2013)
Blood
, vol.121
, pp. 628-637
-
-
Giannoudis, A.1
Wang, L.2
Jorgensen, A.L.3
Xinarianos, G.4
Davies, A.5
Pushpakom, S.6
-
23
-
-
68949106066
-
Predictors of primary imatinib resistance in chronic myelogenous leukemia are distinct from those in secondary imatinib resistance
-
Zhang WW, Cortes JE, Yao H, Zhang L, Reddy NG, Jabbour E, et al. Predictors of primary imatinib resistance in chronic myelogenous leukemia are distinct from those in secondary imatinib resistance. J Clin Oncol 2009; 27: 3642-3649
-
(2009)
J Clin Oncol
, vol.27
, pp. 3642-3649
-
-
Zhang, W.W.1
Cortes, J.E.2
Yao, H.3
Zhang, L.4
Reddy, N.G.5
Jabbour, E.6
-
24
-
-
84892740116
-
Reduced ABCG2 and increased SLC22A1 mRNA expression are associated with imatinib response in chronic myeloid leukemia
-
de Lima LT, Vivona D, Bueno CT, Hirata RD, Hirata MH, Luchessi AD, et al. Reduced ABCG2 and increased SLC22A1 mRNA expression are associated with imatinib response in chronic myeloid leukemia. Med Oncol 2014; 31: 851
-
(2014)
Med Oncol
, vol.31
, pp. 851
-
-
De Lima, L.T.1
Vivona, D.2
Bueno, C.T.3
Hirata, R.D.4
Hirata, M.H.5
Luchessi, A.D.6
-
25
-
-
84943355596
-
OCT-1, ABCB1, and ABCG2 expression in imatinib-resistant chronic myeloid leukemia treated with dasatinib or nilotinib
-
Kim YK, Lee SS, Jeong SH, Ahn JS, Yang DH, Lee JJ, et al. OCT-1, ABCB1, and ABCG2 expression in imatinib-resistant chronic myeloid leukemia treated with dasatinib or nilotinib. Chonnam Med J 2014; 50: 102-111
-
(2014)
Chonnam Med J
, vol.50
, pp. 102-111
-
-
Kim, Y.K.1
Lee, S.S.2
Jeong, S.H.3
Ahn, J.S.4
Yang, D.H.5
Lee, J.J.6
-
26
-
-
84881269230
-
Can "specific" OCT1 inhibitors be used to determine OCT1 transporter activity toward imatinib
-
Burger H, Mathijssen RH, SparreboomA, Wiemer EA. Can "specific" OCT1 inhibitors be used to determine OCT1 transporter activity toward imatinib?. Blood 2013; 121: 4965-4966
-
(2013)
Blood
, vol.121
, pp. 4965-4966
-
-
Burger, H.1
Mathijssen, R.H.2
Sparreboom, A.3
Wiemer, E.A.4
-
27
-
-
53549119190
-
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1
-
Ahlin G, Karlsson J, Pedersen JM, Gustavsson L, Larsson R, Matsson P, et al. Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem 2008; 51: 5932-5942
-
(2008)
J Med Chem
, vol.51
, pp. 5932-5942
-
-
Ahlin, G.1
Karlsson, J.2
Pedersen, J.M.3
Gustavsson, L.4
Larsson, R.5
Matsson, P.6
-
28
-
-
84862148836
-
Chronic phase chronic myeloid leukemia patients with low OCT-1 activity randomized to highdose imatinib achieve better responses and have lower failure rates than those randomized to standard-dose imatinib
-
White DL, Radich J, Soverini S, Saunders VA, Frede AK, Dang P, et al. Chronic phase chronic myeloid leukemia patients with low OCT-1 activity randomized to highdose imatinib achieve better responses and have lower failure rates than those randomized to standard-dose imatinib. Haematologica 2012; 97: 907-914
-
(2012)
Haematologica
, vol.97
, pp. 907-914
-
-
White, D.L.1
Radich, J.2
Soverini, S.3
Saunders, V.A.4
Frede, A.K.5
Dang, P.6
-
29
-
-
84884467573
-
Early switching from imatinib to nilotinib in CML patients failing to achieve early molecular targets may not be an effective approach in patients with very low OCT-1 activity: A TIDEL II Sub-Study
-
White DL, Saunders V, Frede A, GrootObbink K, Slader C, Yeung DT, et al. Early switching from imatinib to nilotinib in CML patients failing to achieve early molecular targets may not be an effective approach in patients with very low OCT-1 activity: A TIDEL II Sub-Study. ASH Annu Meet Abstr 2010; 116: 356
-
(2010)
ASH Annu Meet Abstr
, vol.116
, pp. 356
-
-
White, D.L.1
Saunders, V.2
Frede, A.3
GrootObbink, K.4
Slader, C.5
Yeung, D.T.6
-
30
-
-
84883783205
-
Early molecular response to imatinib in CP-CML patients: The significance of early dose intensity and OCT-1 activity in responders and efficacy of dose escalation and switch to nilotinib in non-responders
-
White DL, Saunders VA, Yeung DT, Grigg A, Hughes TP. Early molecular response to imatinib in CP-CML patients: the significance of early dose intensity and OCT-1 activity in responders and efficacy of dose escalation and switch to nilotinib in non-responders. ASH Annu Meet Abstr 2012; 120: 693
-
(2012)
ASH Annu Meet Abstr
, vol.120
, pp. 693
-
-
White, D.L.1
Saunders, V.A.2
Yeung, D.T.3
Grigg, A.4
Hughes, T.P.5
-
31
-
-
70450255111
-
Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters
-
Davies A, Jordanides NE, Giannoudis A, Lucas CM, Hatziieremia S, Harris RJ, et al. Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters. Leukemia 2009; 23: 1999-2006
-
(2009)
Leukemia
, vol.23
, pp. 1999-2006
-
-
Davies, A.1
Jordanides, N.E.2
Giannoudis, A.3
Lucas, C.M.4
Hatziieremia, S.5
Harris, R.J.6
-
32
-
-
77950959714
-
Chronic myeloid leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 activity
-
Engler JR, Frede A, Saunders VA, Zannettino AC, Hughes TP, White DL. Chronic myeloid leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 activity. Leukemia 2010; 24: 765-770
-
(2010)
Leukemia
, vol.24
, pp. 765-770
-
-
Engler, J.R.1
Frede, A.2
Saunders, V.A.3
Zannettino, A.C.4
Hughes, T.P.5
White, D.L.6
-
33
-
-
13744263546
-
Regulation of organic cation transport
-
Ciarimboli G, Schlatter E. Regulation of organic cation transport. Pflugers Archiv 2005; 449: 423-441
-
(2005)
Pflugers Archiv
, vol.449
, pp. 423-441
-
-
Ciarimboli, G.1
Schlatter, E.2
-
34
-
-
84920269464
-
Proteomics tissue-based map of the human proteome
-
Uhlen M, Fagerberg L, Hallstrom BM, Lindskog C, Oksvold P, Mardinoglu A, et al. Proteomics. Tissue-based map of the human proteome. Science 2015; 347: 1260419
-
(2015)
Science
, vol.347
, pp. 1260419
-
-
Uhlen, M.1
Fagerberg, L.2
Hallstrom, B.M.3
Lindskog, C.4
Oksvold, P.5
Mardinoglu, A.6
-
35
-
-
0141920354
-
Comparing protein abundance and mRNA expression levels on a genomic scale
-
Greenbaum D, Colangelo C, Williams K, Gerstein M. Comparing protein abundance and mRNA expression levels on a genomic scale. Genome Biol 2003; 4: 117
-
(2003)
Genome Biol
, vol.4
, pp. 117
-
-
Greenbaum, D.1
Colangelo, C.2
Williams, K.3
Gerstein, M.4
-
36
-
-
68949205722
-
Correlations between RNA and protein expression profiles in 23 human cell lines
-
Gry M, Rimini R, Stromberg S, Asplund A, Ponten F, Uhlen M, et al. Correlations between RNA and protein expression profiles in 23 human cell lines. BMC Genomics 2009; 10: 365
-
(2009)
BMC Genomics
, vol.10
, pp. 365
-
-
Gry, M.1
Rimini, R.2
Stromberg, S.3
Asplund, A.4
Ponten, F.5
Uhlen, M.6
-
37
-
-
78650949272
-
Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
-
Corbin AS, Agarwal A, Loriaux M, Cortes J, Deininger MW, Druker BJ. Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity. J Clin Invest 2011; 121: 396-409
-
(2011)
J Clin Invest
, vol.121
, pp. 396-409
-
-
Corbin, A.S.1
Agarwal, A.2
Loriaux, M.3
Cortes, J.4
Deininger, M.W.5
Druker, B.J.6
-
38
-
-
77957937825
-
The poor response to imatinib observed in CML patients with low OCT-1 activity is not attributable to lower uptake of imatinib into their CD34+ cells
-
Engler JR, Frede A, Saunders V, Zannettino A, White DL, Hughes TP. The poor response to imatinib observed in CML patients with low OCT-1 activity is not attributable to lower uptake of imatinib into their CD34+ cells. Blood 2010; 116: 2776-2778
-
(2010)
Blood
, vol.116
, pp. 2776-2778
-
-
Engler, J.R.1
Frede, A.2
Saunders, V.3
Zannettino, A.4
White, D.L.5
Hughes, T.P.6
-
39
-
-
79551627900
-
OCT-1 function varies with cell lineage but is not influenced by BCR-ABL
-
Engler JR, Zannettino AC, Bailey CG, Rasko JE, Hughes TP, White DL. OCT-1 function varies with cell lineage but is not influenced by BCR-ABL. Haematologica 2011; 96: 213-220
-
(2011)
Haematologica
, vol.96
, pp. 213-220
-
-
Engler, J.R.1
Zannettino, A.C.2
Bailey, C.G.3
Rasko, J.E.4
Hughes, T.P.5
White, D.L.6
-
40
-
-
84943586597
-
Differential lineage involvement between very low and higher OCT-1 activity chronic-phase CML patients
-
Abstract 1675
-
Watkins DB, Kok CH, Hughes TP, Slader C, D'Andrea RJ, White DL. Differential lineage involvement between very low and higher OCT-1 activity chronic-phase CML patients. ASH Annu Meet Abstr 2011; 118, Abstract 1675
-
(2011)
ASH Annu Meet Abstr
, vol.118
-
-
Watkins, D.B.1
Kok, C.H.2
Hughes, T.P.3
Slader, C.4
D'Andrea, R.J.5
White, D.L.6
-
41
-
-
12344327392
-
Transcriptional regulation of murine Slc22a1 (Oct1) by peroxisome proliferator agonist receptor-Alpha and -gamma
-
Nie W, Sweetser S, Rinella M, Green RM. Transcriptional regulation of murine Slc22a1 (Oct1) by peroxisome proliferator agonist receptor-Alpha and -gamma. Am J Physiol Gastrointest Liver Physiol 2005; 288: G207-G212
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
, pp. G207-G212
-
-
Nie, W.1
Sweetser, S.2
Rinella, M.3
Green, R.M.4
-
42
-
-
84866319957
-
Peroxisome proliferator-Activated receptor activation increases imatinib uptake and killing of chronic myeloid leukemia cells
-
e2
-
Wang L, Giannoudis A, Austin G, Clark RE. Peroxisome proliferator-Activated receptor activation increases imatinib uptake and killing of chronic myeloid leukemia cells. Exp Hematol. 2012; 40: 811-819 e2
-
(2012)
Exp Hematol
, vol.40
, pp. 811-819
-
-
Wang, L.1
Giannoudis, A.2
Austin, G.3
Clark, R.E.4
-
43
-
-
84943579857
-
Role of peroxisome proliferatoractivated receptor gamma (PPAR?) and its ligands in the regulation of functional OCT-1 activity in CML cells
-
Abstract 1470
-
Wang J, Kok C, D'Andrea R, Hughes T, White D. Role Of peroxisome proliferatoractivated receptor gamma (PPAR?) and its ligands in the regulation of functional OCT-1 activity in CML cells. ASH Annu Meet Abstr 2013; 21, Abstract 1470
-
(2013)
ASH Annu Meet Abstr
, vol.21
-
-
Wang, J.1
Kok, C.2
D'Andrea, R.3
Hughes, T.4
White, D.5
-
44
-
-
0036865724
-
Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences
-
Kerb R, Brinkmann U, Chatskaia N, Gorbunov D, Gorboulev V, Mornhinweg E, et al. Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences. Pharmacogenetics 2002; 12: 591-595
-
(2002)
Pharmacogenetics
, vol.12
, pp. 591-595
-
-
Kerb, R.1
Brinkmann, U.2
Chatskaia, N.3
Gorbunov, D.4
Gorboulev, V.5
Mornhinweg, E.6
-
45
-
-
0038184179
-
Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1
-
Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, et al. Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1. Proc Natl Acad Sci USA 2003; 100: 5902-5907
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5902-5907
-
-
Shu, Y.1
Leabman, M.K.2
Feng, B.3
Mangravite, L.M.4
Huang, C.C.5
Stryke, D.6
-
46
-
-
16644372503
-
Seven novel single nucleotide polymorphisms in the human SLC22A1 gene encoding organic cation transporter 1 (OCT1
-
Itoda M, Saito Y, Maekawa K, Hichiya H, Komamura K, Kamakura S, et al. Seven novel single nucleotide polymorphisms in the human SLC22A1 gene encoding organic cation transporter 1 (OCT1). Drug Metab Pharmacokinet 2004; 19: 308-312
-
(2004)
Drug Metab Pharmacokinet
, vol.19
, pp. 308-312
-
-
Itoda, M.1
Saito, Y.2
Maekawa, K.3
Hichiya, H.4
Komamura, K.5
Kamakura, S.6
-
47
-
-
0347859200
-
Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions
-
Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, et al. Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions. Biochem Biophys Res Commun 2004; 313: 789-793
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 789-793
-
-
Sakata, T.1
Anzai, N.2
Shin, H.J.3
Noshiro, R.4
Hirata, T.5
Yokoyama, H.6
-
48
-
-
0038612980
-
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints
-
Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci USA 2003; 100: 5896-5901
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5896-5901
-
-
Leabman, M.K.1
Huang, C.C.2
DeYoung, J.3
Carlson, E.J.4
Taylor, T.R.5
De La Cruz, M.6
-
49
-
-
0038494642
-
TP53 polymorphisms and lung cancer risk: A systematic review and meta-Analysis
-
Matakidou A, Eisen T, Houlston RS. TP53 polymorphisms and lung cancer risk: a systematic review and meta-Analysis. Mutagenesis 2003; 18: 377-385
-
(2003)
Mutagenesis
, vol.18
, pp. 377-385
-
-
Matakidou, A.1
Eisen, T.2
Houlston, R.S.3
-
50
-
-
54749097888
-
A systematic review of meta-Analyses on gene polymorphisms and gastric cancer risk
-
Gianfagna F, De Feo E, van Duijn CM, Ricciardi G, Boccia S. A systematic review of meta-Analyses on gene polymorphisms and gastric cancer risk. Curr Genomics 2008; 9: 361-374
-
(2008)
Curr Genomics
, vol.9
, pp. 361-374
-
-
Gianfagna, F.1
De Feo, E.2
Van Duijn, C.M.3
Ricciardi, G.4
Boccia, S.5
-
51
-
-
0032749945
-
A systematic review of genetic polymorphisms and breast cancer risk
-
Dunning AM, Healey CS, Pharoah PD, Teare MD, Ponder BA, Easton DF. A systematic review of genetic polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev 1999; 8: 843-854
-
(1999)
Cancer Epidemiol Biomarkers Prev
, vol.8
, pp. 843-854
-
-
Dunning, A.M.1
Healey, C.S.2
Pharoah, P.D.3
Teare, M.D.4
Ponder, B.A.5
Easton, D.F.6
-
52
-
-
38349085099
-
Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
-
Shu Y, Brown C, Castro RA, Shi RJ, Lin ET, Owen RP, et al. Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics. Clin Pharmacol Ther 2008; 83: 273-280
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 273-280
-
-
Shu, Y.1
Brown, C.2
Castro, R.A.3
Shi, R.J.4
Lin, E.T.5
Owen, R.P.6
-
53
-
-
34248156160
-
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action
-
Shu Y, Sheardown SA, Brown C, Owen RP, Zhang S, Castro RA, et al. Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest 2007; 117: 1422-1431
-
(2007)
J Clin Invest
, vol.117
, pp. 1422-1431
-
-
Shu, Y.1
Sheardown, S.A.2
Brown, C.3
Owen, R.P.4
Zhang, S.5
Castro, R.A.6
-
54
-
-
44949087480
-
Polymorphism in human organic cation transporters and metformin action
-
Takane H, Shikata E, Otsubo K, Higuchi S, Ieiri I. Polymorphism in human organic cation transporters and metformin action. Pharmacogenomics 2008; 9: 415-422
-
(2008)
Pharmacogenomics
, vol.9
, pp. 415-422
-
-
Takane, H.1
Shikata, E.2
Otsubo, K.3
Higuchi, S.4
Ieiri, I.5
-
55
-
-
84875296042
-
Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy
-
Angelini S, Soverini S, Ravegnini G, Barnett M, Turrini E, Thornquist M, et al. Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy. Haematologica 2013; 98: 193-200
-
(2013)
Haematologica
, vol.98
, pp. 193-200
-
-
Angelini, S.1
Soverini, S.2
Ravegnini, G.3
Barnett, M.4
Turrini, E.5
Thornquist, M.6
-
56
-
-
77954569110
-
HOCT1 transcript levels and single nucleotide polymorphisms as predictive factors for response to imatinib in chronic myeloid leukemia
-
Bazeos A, Marin D, Reid AG, Gerrard G, Milojkovic D, May PC, et al. hOCT1 transcript levels and single nucleotide polymorphisms as predictive factors for response to imatinib in chronic myeloid leukemia. Leukemia 2010; 24: 1243-1245
-
(2010)
Leukemia
, vol.24
, pp. 1243-1245
-
-
Bazeos, A.1
Marin, D.2
Reid, A.G.3
Gerrard, G.4
Milojkovic, D.5
May, P.C.6
-
57
-
-
84904975498
-
The c.480C4G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia
-
Di Paolo A, Polillo M, Capecchi M, Cervetti G, Barate C, Angelini S, et al. The c.480C4G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia. Pharmacogenomics J 2014; 14: 328-335
-
(2014)
Pharmacogenomics J
, vol.14
, pp. 328-335
-
-
Di Paolo, A.1
Polillo, M.2
Capecchi, M.3
Cervetti, G.4
Barate, C.5
Angelini, S.6
-
58
-
-
84887613534
-
A common novel splice variant of SLC22A1 (OCT1) is associated with impaired responses to imatinib in patients with chronic myeloid leukaemia
-
Grinfeld J, Gerrard G, Alikian M, Alonso-Dominguez J, Ale S, Valganon M, et al. A common novel splice variant of SLC22A1 (OCT1) is associated with impaired responses to imatinib in patients with chronic myeloid leukaemia. Br J Haematol 2013; 163: 631-639
-
(2013)
Br J Haematol
, vol.163
, pp. 631-639
-
-
Grinfeld, J.1
Gerrard, G.2
Alikian, M.3
Alonso-Dominguez, J.4
Ale, S.5
Valganon, M.6
-
59
-
-
68049087941
-
Clinical relevance of a pharmacogenetic approach using multiple candidate genes to predict response and resistance to imatinib therapy in chronic myeloid leukemia
-
Kim DH, Sriharsha L, Xu W, Kamel-Reid S, Liu X, Siminovitch K, et al. Clinical relevance of a pharmacogenetic approach using multiple candidate genes to predict response and resistance to imatinib therapy in chronic myeloid leukemia. Clin Cancer Res 2009; 15: 4750-4758
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4750-4758
-
-
Kim, D.H.1
Sriharsha, L.2
Xu, W.3
Kamel-Reid, S.4
Liu, X.5
Siminovitch, K.6
-
60
-
-
84896546378
-
OCT1 genetic variants are associated with long term outcomes in imatinib treated chronic myeloid leukemia patients
-
Koren-Michowitz M, Buzaglo Z, Ribakovsky E, Schwarz M, Pessach I, Shimoni A, et al. OCT1 genetic variants are associated with long term outcomes in imatinib treated chronic myeloid leukemia patients. Eur J Haematol 2014; 92: 283-288
-
(2014)
Eur J Haematol
, vol.92
, pp. 283-288
-
-
Koren-Michowitz, M.1
Buzaglo, Z.2
Ribakovsky, E.3
Schwarz, M.4
Pessach, I.5
Shimoni, A.6
-
61
-
-
79960284293
-
Correlation between genetic polymorphisms of the hOCT1 and MDR1 genes and the response to imatinib in patients newly diagnosed with chronic-phase chronic myeloid leukemia
-
Maffioli M, Camos M, Gaya A, Hernandez-Boluda JC, Alvarez-Larran A, Domingo A, et al. Correlation between genetic polymorphisms of the hOCT1 and MDR1 genes and the response to imatinib in patients newly diagnosed with chronic-phase chronic myeloid leukemia. Leuk Res 2011; 35: 1014-1019
-
(2011)
Leuk Res
, vol.35
, pp. 1014-1019
-
-
Maffioli, M.1
Camos, M.2
Gaya, A.3
Hernandez-Boluda, J.C.4
Alvarez-Larran, A.5
Domingo, A.6
-
62
-
-
78649522748
-
Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia
-
Takahashi N, Miura M, Scott SA, Kagaya H, Kameoka Y, Tagawa H, et al. Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia. J Hum Genetics 2010; 55: 731-737
-
(2010)
J Hum Genetics
, vol.55
, pp. 731-737
-
-
Takahashi, N.1
Miura, M.2
Scott, S.A.3
Kagaya, H.4
Kameoka, Y.5
Tagawa, H.6
-
63
-
-
84874568893
-
Influence of enzyme and transporter polymorphisms on trough imatinib concentration and clinical response in chronic myeloid leukemia patients
-
Seong SJ, Lim M, Sohn SK, Moon JH, Oh SJ, Kim BS, et al. Influence of enzyme and transporter polymorphisms on trough imatinib concentration and clinical response in chronic myeloid leukemia patients. Ann Oncol 2013; 24: 756-760
-
(2013)
Ann Oncol
, vol.24
, pp. 756-760
-
-
Seong, S.J.1
Lim, M.2
Sohn, S.K.3
Moon, J.H.4
Oh, S.J.5
Kim, B.S.6
-
64
-
-
84871290097
-
SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia
-
Singh O, Chan JY, Lin K, Heng CC, Chowbay B. SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia. PLoS ONE 2012; 7: e51771
-
(2012)
PLoS ONE
, vol.7
, pp. e51771
-
-
Singh, O.1
Chan, J.Y.2
Lin, K.3
Heng, C.C.4
Chowbay, B.5
-
65
-
-
84912141333
-
Polymorphisms in the human organic cation transporter and the multidrug resistance gene: Correlation with imatinib levels and clinical course in patients with chronic myeloid leukemia
-
Vine J, Cohen SB, Ruchlemer R, Goldschmidt N, Levin M, Libster D, et al. Polymorphisms in the human organic cation transporter and the multidrug resistance gene: correlation with imatinib levels and clinical course in patients with chronic myeloid leukemia. Leuk Lymphoma 2014; 55: 2525-2531
-
(2014)
Leuk Lymphoma
, vol.55
, pp. 2525-2531
-
-
Vine, J.1
Cohen, S.B.2
Ruchlemer, R.3
Goldschmidt, N.4
Levin, M.5
Libster, D.6
-
66
-
-
57049129248
-
OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients
-
Zach O, Krieger O, Foedermayr M, Zellhofer B, Lutz D. OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients. Leuk Lymphoma 2008; 49: 2222-2223
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 2222-2223
-
-
Zach, O.1
Krieger, O.2
Foedermayr, M.3
Zellhofer, B.4
Lutz, D.5
-
67
-
-
84899694121
-
Does the haplotype Met408-Del420, which was apparently predictive for imatinib efficacy, really exist and how strongly may it affect OCT1 activity
-
Tzvetkov MV, Seitz T, Bokelmann K, Mueller T, Brockmoller J, Koepsell H. Does the haplotype Met408-Del420, which was apparently predictive for imatinib efficacy, really exist and how strongly may it affect OCT1 activity?. Blood 2014; 123: 1427-1429
-
(2014)
Blood
, vol.123
, pp. 1427-1429
-
-
Tzvetkov, M.V.1
Seitz, T.2
Bokelmann, K.3
Mueller, T.4
Brockmoller, J.5
Koepsell, H.6
-
68
-
-
1542608328
-
Pharmacokinetics and pharmacodynamics of imatinib in a phase i trial with chronic myeloid leukemia patients
-
Peng B, Hayes M, Resta D, Racine-Poon A, Druker BJ, Talpaz M, et al. Pharmacokinetics and pharmacodynamics of imatinib in a phase I trial with chronic myeloid leukemia patients. J Clin Oncol 2004; 22: 935-942
-
(2004)
J Clin Oncol
, vol.22
, pp. 935-942
-
-
Peng, B.1
Hayes, M.2
Resta, D.3
Racine-Poon, A.4
Druker, B.J.5
Talpaz, M.6
-
69
-
-
78951477012
-
Association of SLCO1B3 polymorphism with intracellular accumulation of imatinib in leukocytes in patients with chronic myeloid leukemia
-
Nambu T, Hamada A, Nakashima R, Yuki M, Kawaguchi T, Mitsuya H, et al. Association of SLCO1B3 polymorphism with intracellular accumulation of imatinib in leukocytes in patients with chronic myeloid leukemia. Biol Pharm Bull 2011; 34: 114-119
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 114-119
-
-
Nambu, T.1
Hamada, A.2
Nakashima, R.3
Yuki, M.4
Kawaguchi, T.5
Mitsuya, H.6
-
70
-
-
77950943180
-
Nilotinib does not significantly reduce imatinib OCT-1 activity in either cell lines or primary CML cells
-
Eadie L, Hughes TP, White DL. Nilotinib does not significantly reduce imatinib OCT-1 activity in either cell lines or primary CML cells. Leukemia 2010; 24: 855-857
-
(2010)
Leukemia
, vol.24
, pp. 855-857
-
-
Eadie, L.1
Hughes, T.P.2
White, D.L.3
-
71
-
-
52449100460
-
Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: Therapeutic implications
-
Hiwase DK, Saunders V, Hewett D, Frede A, Zrim S, Dang P, et al. Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications. Clin Cancer Res 2008; 14: 3881-3888
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3881-3888
-
-
Hiwase, D.K.1
Saunders, V.2
Hewett, D.3
Frede, A.4
Zrim, S.5
Dang, P.6
-
72
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova VD, Wintle RF, Rubin LA, Amos CI, Huang Q, Gu X, et al. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat Genetics 2004; 36: 471-475
-
(2004)
Nat Genetics
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
Wintle, R.F.2
Rubin, L.A.3
Amos, C.I.4
Huang, Q.5
Gu, X.6
-
73
-
-
0032696186
-
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): Its pharmacological and toxicological relevance
-
Ohashi R, Tamai I, Yabuuchi H, Nezu JI, Oku A, Sai Y, et al. Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. J Pharmacol Exp Ther 1999; 291: 778-784
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 778-784
-
-
Ohashi, R.1
Tamai, I.2
Yabuuchi, H.3
Nezu, J.I.4
Oku, A.5
Sai, Y.6
-
74
-
-
0032935034
-
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations
-
Yabuuchi H, Tamai I, Nezu J, Sakamoto K, Oku A, Shimane M, et al. Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. J Pharmacol Exp Ther 1999; 289: 768-773
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 768-773
-
-
Yabuuchi, H.1
Tamai, I.2
Nezu, J.3
Sakamoto, K.4
Oku, A.5
Shimane, M.6
-
75
-
-
0031846917
-
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa
-
Zhang L, Schaner ME, Giacomini KM. Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). J Pharmacol Exp Ther 1998; 286: 354-361
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 354-361
-
-
Zhang, L.1
Schaner, M.E.2
Giacomini, K.M.3
-
76
-
-
0033829943
-
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney
-
Wu X, Huang W, Ganapathy ME, Wang H, Kekuda R, Conway SJ, et al. Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney. Am J Physiol Renal Physiol 2000; 279: F449-F458
-
(2000)
Am J Physiol Renal Physiol
, vol.279
, pp. F449-F458
-
-
Wu, X.1
Huang, W.2
Ganapathy, M.E.3
Wang, H.4
Kekuda, R.5
Conway, S.J.6
-
77
-
-
20744450287
-
Characterization of the organic cation transporter SLC22A16: A doxorubicin importer
-
Okabe M, Unno M, Harigae H, Kaku M, Okitsu Y, Sasaki T, et al. Characterization of the organic cation transporter SLC22A16: a doxorubicin importer. Biochem Biophys Res Commun 2005; 333: 754-762
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 754-762
-
-
Okabe, M.1
Unno, M.2
Harigae, H.3
Kaku, M.4
Okitsu, Y.5
Sasaki, T.6
-
78
-
-
0031824347
-
Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine
-
Busch AE, Karbach U, Miska D, Gorboulev V, Akhoundova A, Volk C, et al. Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine. Mol Pharmacol 1998; 54: 342-352
-
(1998)
Mol Pharmacol
, vol.54
, pp. 342-352
-
-
Busch, A.E.1
Karbach, U.2
Miska, D.3
Gorboulev, V.4
Akhoundova, A.5
Volk, C.6
-
79
-
-
15744362693
-
Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2
-
Suhre WM, Ekins S, Chang C, Swaan PW, Wright SH. Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2. Mol Pharmacol 2005; 67: 1067-1077
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1067-1077
-
-
Suhre, W.M.1
Ekins, S.2
Chang, C.3
Swaan, P.W.4
Wright, S.H.5
-
80
-
-
33744513103
-
Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain
-
Amphoux A, Vialou V, Drescher E, Bruss M, Mannoury La Cour C, Rochat C, et al. Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain. Neuropharmacology 2006; 50: 941-952
-
(2006)
Neuropharmacology
, vol.50
, pp. 941-952
-
-
Amphoux, A.1
Vialou, V.2
Drescher, E.3
Bruss, M.4
Mannoury La Cour, C.5
Rochat, C.6
-
81
-
-
0036022593
-
Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3
-
Hayer-Zillgen M, Bruss M, Bonisch H. Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3. Br J Pharmacol 2002; 136: 829-836
-
(2002)
Br J Pharmacol
, vol.136
, pp. 829-836
-
-
Hayer-Zillgen, M.1
Bruss, M.2
Bonisch, H.3
-
82
-
-
0032553546
-
Transport of monoamine transmitters by the organic cation transporter type 2, OCT2
-
Grundemann D, Koster S, Kiefer N, Breidert T, Engelhardt M, Spitzenberger F, et al. Transport of monoamine transmitters by the organic cation transporter type 2, OCT2. J Biol Chem 1998; 273: 30915-30920
-
(1998)
J Biol Chem
, vol.273
, pp. 30915-30920
-
-
Grundemann, D.1
Koster, S.2
Kiefer, N.3
Breidert, T.4
Engelhardt, M.5
Spitzenberger, F.6
-
83
-
-
0030763035
-
Cloning and characterization of two human polyspecific organic cation transporters
-
Gorboulev V, Ulzheimer JC, Akhoundova A, Ulzheimer-Teuber I, Karbach U, Quester S, et al. Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol 1997; 16: 871-881
-
(1997)
DNA Cell Biol
, vol.16
, pp. 871-881
-
-
Gorboulev, V.1
Ulzheimer, J.C.2
Akhoundova, A.3
Ulzheimer-Teuber, I.4
Karbach, U.5
Quester, S.6
-
84
-
-
0030915085
-
Cloning and functional expression of a human liver organic cation transporter
-
Zhang L, Dresser MJ, Gray AT, Yost SC, Terashita S, Giacomini KM. Cloning and functional expression of a human liver organic cation transporter. Mol Pharmacol 1997; 51: 913-921
-
(1997)
Mol Pharmacol
, vol.51
, pp. 913-921
-
-
Zhang, L.1
Dresser, M.J.2
Gray, A.T.3
Yost, S.C.4
Terashita, S.5
Giacomini, K.M.6
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