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Volumn 34, Issue 1, 2015, Pages

Long noncoding RNA lncTCF7, induced by IL-6/STAT3 transactivation, promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transition

Author keywords

Epithelial mesenchymal transition; Hepatocellular carcinoma; Interleukin 6; Long noncoding RNA

Indexed keywords

INTERLEUKIN 6; LONG UNTRANSLATED RNA; PROTEIN SWI; STAT3 PROTEIN; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR SNF; IL6 PROTEIN, HUMAN; SMALL INTERFERING RNA; STAT3 PROTEIN, HUMAN; TCF7 PROTEIN, HUMAN;

EID: 84943545723     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-015-0229-3     Document Type: Article
Times cited : (118)

References (41)
  • 1
    • 77957603190 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting
    • 2940397 20679622
    • Thomas MB, Jaffe D, Choti MM, Belghiti J, Curley S, Fong Y, et al. Hepatocellular carcinoma: consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting. J Clin Oncol. 2010;28(25):3994-4005.
    • (2010) J Clin Oncol , vol.28 , Issue.25 , pp. 3994-4005
    • Thomas, M.B.1    Jaffe, D.2    Choti, M.M.3    Belghiti, J.4    Curley, S.5    Fong, Y.6
  • 3
    • 84921826637 scopus 로고    scopus 로고
    • Epidemiology of hepatocellular carcinoma in the United States: Where are we? Where do we go?
    • 24839253
    • El-Serag HB, Kanwal F. Epidemiology of hepatocellular carcinoma in the United States: where are we? Where do we go? Hepatology. 2014;60(5):1767-75.
    • (2014) Hepatology , vol.60 , Issue.5 , pp. 1767-1775
    • El-Serag, H.B.1    Kanwal, F.2
  • 4
    • 84924099606 scopus 로고    scopus 로고
    • Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge
    • 4339002 25884472
    • Deng L, Yang SB, Xu FF, Zhang JH. Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge. J Exp Clin Cancer Res. 2015;34:18.
    • (2015) J Exp Clin Cancer Res. , vol.34 , pp. 18
    • Deng, L.1    Yang, S.B.2    Xu, F.F.3    Zhang, J.H.4
  • 5
    • 84935444289 scopus 로고    scopus 로고
    • Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma
    • 4493986 26126858
    • Du C, Weng X, Hu W, Lv Z, Xiao H, Ding C, et al. Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma. J Exp Clin Cancer Res. 2015;34:67.
    • (2015) J Exp Clin Cancer Res. , vol.34 , pp. 67
    • Du, C.1    Weng, X.2    Hu, W.3    Lv, Z.4    Xiao, H.5    Ding, C.6
  • 6
    • 84867212593 scopus 로고    scopus 로고
    • Chronic inflammation, immune escape, and oncogenesis in the liver: A unique neighborhood for novel intersections
    • 3381981 1:CAS:528:DC%2BC38XhsVKmur%2FL 22378061
    • Stauffer JK, Scarzello AJ, Jiang Q, Wiltrout RH. Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections. Hepatology. 2012;56(4):1567-74.
    • (2012) Hepatology , vol.56 , Issue.4 , pp. 1567-1574
    • Stauffer, J.K.1    Scarzello, A.J.2    Jiang, Q.3    Wiltrout, R.H.4
  • 7
    • 84919848147 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • 24954675
    • Trépo C, Chan HL, Lok A. Hepatitis B virus infection. Lancet. 2014;384(9959):2053-63.
    • (2014) Lancet , vol.384 , Issue.9959 , pp. 2053-2063
    • Trépo, C.1    Chan, H.L.2    Lok, A.3
  • 8
    • 84942513943 scopus 로고    scopus 로고
    • Worldwide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma
    • doi: 10.1002/hep.27969. [Epub ahead of print]
    • de Martel C, Maucort-Boulch D, Plummer M, Franceschi S. Worldwide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma. Hepatology. 2015; 3. doi: 10.1002/hep.27969. [Epub ahead of print]
    • (2015) Hepatology. , vol.3
    • De Martel, C.1    Maucort-Boulch, D.2    Plummer, M.3    Franceschi, S.4
  • 9
    • 84920531875 scopus 로고    scopus 로고
    • Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression
    • 1:CAS:528:DC%2BC2MXis12mtw%3D%3D 25564572
    • Chang TS, Wu YC, Chi CC, Su WC, Chang PJ, Lee KF, et al. Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression. Clin Cancer Res. 2015;21(1):201-10.
    • (2015) Clin Cancer Res , vol.21 , Issue.1 , pp. 201-210
    • Chang, T.S.1    Wu, Y.C.2    Chi, C.C.3    Su, W.C.4    Chang, P.J.5    Lee, K.F.6
  • 10
    • 84928012372 scopus 로고    scopus 로고
    • CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression
    • 1:CAS:528:DC%2BC2cXhvVentLfL 25341042
    • Lin L, Han MM, Wang F, Xu LL, Yu HX, Yang PY. CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression. Cell Death Dis. 2014;5, e1488.
    • (2014) Cell Death Dis. , vol.5 , pp. e1488
    • Lin, L.1    Han, M.M.2    Wang, F.3    Xu, L.L.4    Yu, H.X.5    Yang, P.Y.6
  • 11
    • 84900316922 scopus 로고    scopus 로고
    • A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma
    • 1:CAS:528:DC%2BC2cXntFGgsrY%3D 24768205
    • Yuan JH, Yang F, Wang F, Ma JZ, Guo YJ, Tao QF, et al. A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma. Cancer Cell. 2014;25(5):666-81.
    • (2014) Cancer Cell , vol.25 , Issue.5 , pp. 666-681
    • Yuan, J.H.1    Yang, F.2    Wang, F.3    Ma, J.Z.4    Guo, Y.J.5    Tao, Q.F.6
  • 12
    • 84913580379 scopus 로고    scopus 로고
    • Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells
    • 1:CAS:528:DC%2BC2cXhvFOgsr%2FL 25181692
    • Wan S, Zhao E, Kryczek I, Vatan L, Sadovskaya A, Ludema G, et al. Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells. Gastroenterology. 2014;147(6):1393-404.
    • (2014) Gastroenterology , vol.147 , Issue.6 , pp. 1393-1404
    • Wan, S.1    Zhao, E.2    Kryczek, I.3    Vatan, L.4    Sadovskaya, A.5    Ludema, G.6
  • 13
    • 84941342205 scopus 로고    scopus 로고
    • The relationship between serum interleukin-6 and the recurrence of hepatitis B virus related hepatocellular carcinoma after curative resection
    • 1:CAS:528:DC%2BC2MXhtVOnu77L
    • Sheng T, Wang B, Wang SY, Deng B, Qu L, Qi XS, et al. The relationship between serum interleukin-6 and the recurrence of hepatitis B virus related hepatocellular carcinoma after curative resection. Medicine (Baltimore). 2015;94(24), e941.
    • (2015) Medicine (Baltimore) , vol.94 , Issue.24 , pp. e941
    • Sheng, T.1    Wang, B.2    Wang, S.Y.3    Deng, B.4    Qu, L.5    Qi, X.S.6
  • 14
    • 84928886925 scopus 로고    scopus 로고
    • IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: A cohort study
    • 4424593 25908103
    • Kao JT, Feng CL, Yu CJ, Tsai SM, Hsu PN, Chen YL, et al. IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: a cohort study. BMC Gastroenterol. 2015;15:50.
    • (2015) BMC Gastroenterol. , vol.15 , pp. 50
    • Kao, J.T.1    Feng, C.L.2    Yu, C.J.3    Tsai, S.M.4    Hsu, P.N.5    Chen, Y.L.6
  • 15
    • 84860562350 scopus 로고    scopus 로고
    • Uncovering the role of genomic "dark matter" in human disease
    • 3336981 1:CAS:528:DC%2BC38Xmslyqu74%3D 22546862
    • Martin L, Chang HY. Uncovering the role of genomic "dark matter" in human disease. J Clin Invest. 2012;122(5):1589-95.
    • (2012) J Clin Invest , vol.122 , Issue.5 , pp. 1589-1595
    • Martin, L.1    Chang, H.Y.2
  • 16
    • 84926215418 scopus 로고    scopus 로고
    • The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling
    • 1:CAS:528:DC%2BC2MXltVWrsbc%3D 25842979
    • Wang Y, He L, Du Y, Zhu P, Huang G, Luo J, et al. The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling. Cell Stem Cell. 2015;16(4):413-25.
    • (2015) Cell Stem Cell , vol.16 , Issue.4 , pp. 413-425
    • Wang, Y.1    He, L.2    Du, Y.3    Zhu, P.4    Huang, G.5    Luo, J.6
  • 17
    • 84940417323 scopus 로고    scopus 로고
    • Malat1 regulates serum response factor through miR-133 as a competing endogenous RNA in myogenesis
    • 25868726
    • Han X, Yang F, Cao H, Liang Z. Malat1 regulates serum response factor through miR-133 as a competing endogenous RNA in myogenesis. FASEB J. 2015;29(7):3054-64.
    • (2015) FASEB J , vol.29 , Issue.7 , pp. 3054-3064
    • Han, X.1    Yang, F.2    Cao, H.3    Liang, Z.4
  • 18
    • 84924411357 scopus 로고    scopus 로고
    • A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice
    • 1:CAS:528:DC%2BC2MXjt1ejurk%3D 25738460
    • Li P, Ruan X, Yang L, Kiesewetter K, Zhao Y, Luo H, et al. A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice. Cell Metab. 2015;21(3):455-67.
    • (2015) Cell Metab , vol.21 , Issue.3 , pp. 455-467
    • Li, P.1    Ruan, X.2    Yang, L.3    Kiesewetter, K.4    Zhao, Y.5    Luo, H.6
  • 19
    • 84908020927 scopus 로고    scopus 로고
    • A long noncoding RNA protects the heart from pathological hypertrophy
    • 4184960 1:CAS:528:DC%2BC2cXhs1yhsLvL 25119045
    • Han P, Li W, Lin CH, Yang J, Shang C, Nurnberg ST, et al. A long noncoding RNA protects the heart from pathological hypertrophy. Nature. 2014;514(7520):102-6.
    • (2014) Nature , vol.514 , Issue.7520 , pp. 102-106
    • Han, P.1    Li, W.2    Lin, C.H.3    Yang, J.4    Shang, C.5    Nurnberg, S.T.6
  • 20
    • 84927933097 scopus 로고    scopus 로고
    • A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma
    • 1:CAS:528:DC%2BC2cXitVylu7%2FE 25476897
    • Tang J, Zhuo H, Zhang X, Jiang R, Ji J, Deng L, et al. A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma. Cell Death Dis. 2014;5, e1549.
    • (2014) Cell Death Dis. , vol.5 , pp. e1549
    • Tang, J.1    Zhuo, H.2    Zhang, X.3    Jiang, R.4    Ji, J.5    Deng, L.6
  • 21
    • 84938412183 scopus 로고    scopus 로고
    • Hotair Mediates Hepatocarcinogenesis through Suppressing MiRNA-218 Expression and Activating P14 and P16 Signaling
    • Epub ahead of print
    • Fu WM, Zhu X, Wang WM, Lu YF, Hu BG, Wang H, et al. Hotair Mediates Hepatocarcinogenesis through Suppressing MiRNA-218 Expression and Activating P14 and P16 Signaling. J Hepatol. 2015; 26. S0168-8278(15)00343-8. doi: 10.1016/j.jhep.2015.05.016. [Epub ahead of print]
    • (2015) J Hepatol. , vol.26 , pp. S01688278-15003438
    • Fu, W.M.1    Zhu, X.2    Wang, W.M.3    Lu, Y.F.4    Hu, B.G.5    Wang, H.6
  • 22
    • 84874789694 scopus 로고    scopus 로고
    • Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma
    • 23222811
    • Zhang L, Yang F, Yuan JH, Yuan SX, Zhou WP, Huo XS, et al. Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma. Carcinogenesis. 2013;34(3):577-86.
    • (2013) Carcinogenesis , vol.34 , Issue.3 , pp. 577-586
    • Zhang, L.1    Yang, F.2    Yuan, J.H.3    Yuan, S.X.4    Zhou, W.P.5    Huo, X.S.6
  • 23
    • 84956733955 scopus 로고    scopus 로고
    • Long noncoding RNA DANCR increases stemness features of hepatocellular carcinoma via de-repression of CTNNB1
    • doi: 10.1002/hep.27893. [Epub ahead of print]
    • Yuan SX, Wang J, Yang F, Tao QF, Zhang J, Wang LL, et al. Long noncoding RNA DANCR increases stemness features of hepatocellular carcinoma via de-repression of CTNNB1. Hepatology. 2015; doi: 10.1002/hep.27893. [Epub ahead of print]
    • (2015) Hepatology.
    • Yuan, S.X.1    Wang, J.2    Yang, F.3    Tao, Q.F.4    Zhang, J.5    Wang, L.L.6
  • 24
    • 84876718756 scopus 로고    scopus 로고
    • Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin
    • 1:CAS:528:DC%2BC3sXms1egs7c%3D 23239537
    • Huang JF, Guo YJ, Zhao CX, Yuan SX, Wang Y, Tang GN, et al. Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin. Hepatology. 2013;57(5):1882-92.
    • (2013) Hepatology , vol.57 , Issue.5 , pp. 1882-1892
    • Huang, J.F.1    Guo, Y.J.2    Zhao, C.X.3    Yuan, S.X.4    Wang, Y.5    Tang, G.N.6
  • 25
    • 84870530823 scopus 로고    scopus 로고
    • Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients' poor recurrence-free survival after hepatectomy
    • 1:CAS:528:DC%2BC38XhvVSmtbzP 22706893
    • Yuan SX, Yang F, Yang Y, Tao QF, Zhang J, Huang G, et al. Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients' poor recurrence-free survival after hepatectomy. Hepatology. 2012;56(6):2231-41.
    • (2012) Hepatology , vol.56 , Issue.6 , pp. 2231-2241
    • Yuan, S.X.1    Yang, F.2    Yang, Y.3    Tao, Q.F.4    Zhang, J.5    Huang, G.6
  • 26
    • 80055046798 scopus 로고    scopus 로고
    • Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans
    • 1:CAS:528:DC%2BC3MXhtlygsb3I 21769904
    • Yang F, Zhang L, Huo XS, Yuan JH, Xu D, Yuan SX, et al. Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology. 2011;54(5):1679-89.
    • (2011) Hepatology , vol.54 , Issue.5 , pp. 1679-1689
    • Yang, F.1    Zhang, L.2    Huo, X.S.3    Yuan, J.H.4    Xu, D.5    Yuan, S.X.6
  • 27
    • 84887020835 scopus 로고    scopus 로고
    • Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)
    • 23728852
    • Hämmerle M, Gutschner T, Uckelmann H, Ozgur S, Fiskin E, Gross M, et al. Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1). Hepatology. 2013;58(5):1703-12.
    • (2013) Hepatology , vol.58 , Issue.5 , pp. 1703-1712
    • Hämmerle, M.1    Gutschner, T.2    Uckelmann, H.3    Ozgur, S.4    Fiskin, E.5    Gross, M.6
  • 28
    • 84875810883 scopus 로고    scopus 로고
    • Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis
    • 1:CAS:528:DC%2BC3sXit12itLw%3D 23395002
    • Yang F, Huo XS, Yuan SX, Zhang L, Zhou WP, Wang F, et al. Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis. Mol Cell. 2013;49(6):1083-96.
    • (2013) Mol Cell , vol.49 , Issue.6 , pp. 1083-1096
    • Yang, F.1    Huo, X.S.2    Yuan, S.X.3    Zhang, L.4    Zhou, W.P.5    Wang, F.6
  • 29
    • 84927743632 scopus 로고    scopus 로고
    • Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2
    • 1:CAS:528:DC%2BC2cXhs1Wlu7zE 25043274
    • Wang F, Yuan JH, Wang SB, Yang F, Yuan SX, Ye C, et al. Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2. Hepatology. 2014;60(4):1278-90.
    • (2014) Hepatology , vol.60 , Issue.4 , pp. 1278-1290
    • Wang, F.1    Yuan, J.H.2    Wang, S.B.3    Yang, F.4    Yuan, S.X.5    Ye, C.6
  • 30
    • 84887456252 scopus 로고    scopus 로고
    • The epigenetics of epithelial-mesenchymal plasticity in cancer
    • 4190672 1:CAS:528:DC%2BC3sXhslCnur%2FI 24202396
    • Tam WL, Weinberg RA. The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat Med. 2013;19(11):1438-49.
    • (2013) Nat Med , vol.19 , Issue.11 , pp. 1438-1449
    • Tam, W.L.1    Weinberg, R.A.2
  • 31
    • 84887273608 scopus 로고    scopus 로고
    • Epithelial plasticity: A common theme in embryonic and cancer cells
    • 24202173
    • Nieto MA. Epithelial plasticity: a common theme in embryonic and cancer cells. Science. 2013;342(6159):1234850.
    • (2013) Science , vol.342 , Issue.6159 , pp. 1234850
    • Nieto, M.A.1
  • 32
    • 84878011051 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer
    • 4424043 1:CAS:528:DC%2BC3sXjtVSju70%3D 23561968
    • Rhim AD. Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer. Pancreatology. 2013;13(2):114-7.
    • (2013) Pancreatology , vol.13 , Issue.2 , pp. 114-117
    • Rhim, A.D.1
  • 33
    • 84927628854 scopus 로고    scopus 로고
    • Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition
    • 4392608 25750173
    • Liu H, Ren G, Wang T, Chen Y, Gong C, Bai Y, et al. Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition. Carcinogenesis. 2015;36(4):459-68.
    • (2015) Carcinogenesis , vol.36 , Issue.4 , pp. 459-468
    • Liu, H.1    Ren, G.2    Wang, T.3    Chen, Y.4    Gong, C.5    Bai, Y.6
  • 34
    • 84942292465 scopus 로고    scopus 로고
    • Inflammation and cancer: Advances and new agents
    • doi: 10.1038/nrclinonc.2015.105. [Epub ahead of print]
    • Crusz SM, Balkwill FR. Inflammation and cancer: advances and new agents. Nat Rev Clin Oncol. 2015; doi: 10.1038/nrclinonc.2015.105. [Epub ahead of print]
    • (2015) Nat Rev Clin Oncol.
    • Crusz, S.M.1    Balkwill, F.R.2
  • 35
    • 82655189564 scopus 로고    scopus 로고
    • STAT3 is necessary for proliferation and survival in colon cancer-initiating cells
    • 4295768 1:CAS:528:DC%2BC3MXhsFCmsb%2FE 21900397
    • Lin L, Liu A, Peng Z, Lin HJ, Li PK, Li C, et al. STAT3 is necessary for proliferation and survival in colon cancer-initiating cells. Cancer Res. 2011;71(23):7226-37.
    • (2011) Cancer Res , vol.71 , Issue.23 , pp. 7226-7237
    • Lin, L.1    Liu, A.2    Peng, Z.3    Lin, H.J.4    Li, P.K.5    Li, C.6    Lin, J.7
  • 37
    • 84959319525 scopus 로고    scopus 로고
    • Targeting JAK kinase in solid tumors: Emerging opportunities and challenges
    • May 18. doi: 10.1038/onc.2015.150. [Epub ahead of print]
    • Buchert M, Burns CJ, Ernst M. Targeting JAK kinase in solid tumors: emerging opportunities and challenges. Oncogene. 2015 May 18. doi: 10.1038/onc.2015.150. [Epub ahead of print]
    • (2015) Oncogene.
    • Buchert, M.1    Burns, C.J.2    Ernst, M.3
  • 38
    • 84911377275 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract
    • 1:CAS:528:DC%2BC2cXhvFCiurjP 25447409
    • Liu Y, Luo F, Xu Y, Wang B, Zhao Y, Xu W, et al. Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract. Toxicol Appl Pharmacol. 2015;282(1):9-19.
    • (2015) Toxicol Appl Pharmacol , vol.282 , Issue.1 , pp. 9-19
    • Liu, Y.1    Luo, F.2    Xu, Y.3    Wang, B.4    Zhao, Y.5    Xu, W.6
  • 39
    • 84940031281 scopus 로고    scopus 로고
    • Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A
    • Jun 3. pii: blood-2014-12-618678. [Epub ahead of print]
    • Li Y, Shi Y, McCaw L, Li YJ, Zhu F, Gorczynski R, et al. Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A. Blood. 2015 Jun 3. pii: blood-2014-12-618678. [Epub ahead of print]
    • (2015) Blood.
    • Li, Y.1    Shi, Y.2    McCaw, L.3    Li, Y.J.4    Zhu, F.5    Gorczynski, R.6
  • 40
    • 84907917653 scopus 로고    scopus 로고
    • Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression
    • 1:CAS:528:DC%2BC2cXhs1Wjs7%2FE 25087183
    • Li CH, Xu F, Chow S, Feng L, Yin D, Ng TB, et al. Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression. Eur J Cancer. 2014;50(15):2560-9.
    • (2014) Eur J Cancer , vol.50 , Issue.15 , pp. 2560-2569
    • Li, C.H.1    Xu, F.2    Chow, S.3    Feng, L.4    Yin, D.5    Ng, T.B.6
  • 41
    • 84897561550 scopus 로고    scopus 로고
    • IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
    • 3973098 1:CAS:528:DC%2BC2cXmtVGgur4%3D 24642471
    • Rokavec M, Öner MG, Li H, Jackstadt R, Jiang L, Lodygin D, et al. IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. J Clin Invest. 2014;124(4):1853-67.
    • (2014) J Clin Invest , vol.124 , Issue.4 , pp. 1853-1867
    • Rokavec, M.1    Öner, M.G.2    Li, H.3    Jackstadt, R.4    Jiang, L.5    Lodygin, D.6


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