Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression

European Journal of Cancer

Volumn 50, Issue 15, 2014, Pages 2560-2569

  Li, Chi Han ^a   Xu, Feiyue ^a   Chow, Sheungching ^a   Feng, Lu ^a   Yin, Deling ^b   Ng, Tzi Bun ^a   Chen, Yangchao ^a,c  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b East Tennessee State University   (United States)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Hepatitis B virus; Hepatitis B X protein; Hepatocellular carcinoma; Interleukin 6; MicroRNA 21

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; INTERLEUKIN 6; MICRORNA; MIRN21 MICRORNA, MOUSE; STAT3 PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CELL TRANSFORMATION; CYTOLOGY; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; HUMAN; LIVER CELL; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METABOLISM; MOUSE; MUTATION; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION; HEK293 CELLS; HEPATOCYTES; HUMANS; INTERLEUKIN-6; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; MUTATION; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84907917653     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.07.008     Document Type: Article

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