Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling

Journal of Hepatology

Volumn 63, Issue 4, 2015, Pages 886-895

  Fu, Wei Ming ^b,c   Zhu, Xiao ^b,d   Wang, Wei Mao ^b   Lu, Ying Fei ^a   Hu, Bao Guang ^e   Wang, Hua ^f   Liang, Wei Cheng ^b   Wang, Shan Shan ^f   Ko, Chun Hay ^f   Waye, Mary Miu Yee ^b   Kung, Hsiang Fu ^b,f   Li, Gang ^a,b,f   Zhang, Jin Fang ^a,b,f  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^d GUANGDONG MEDICAL UNIVERSITY   (China)

^e BINZHOU MEDICAL UNIVERSITY   (China)

^f CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Hepatocellular carcinoma; Hotair; microR 218; P14; P16

Indexed keywords

BMI1 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HOTAIR; LONG UNTRANSLATED RNA; MICRORNA; MICRORNA 218; PROTEIN P14; PROTEIN P16; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; HOTAIR LONG NON-CODING RNA, MOUSE; LAMTOR2 PROTEIN, MOUSE; MIRN218 MICRORNA, MOUSE; P16 PROTEIN, HUMAN; PROTEIN; RNA; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CARCINOGENESIS; LUCIFERASE ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; BIOSYNTHESIS; CARCINOGENESIS; CELL PROLIFERATION; CELL SURVIVAL; EXPERIMENTAL LIVER NEOPLASM; GENE EXPRESSION REGULATION; GENETICS; LIVER CELL CARCINOMA; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPRECIPITATION; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICRORNAS; NEOPLASM PROTEINS; PROMOTER REGIONS, GENETIC; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, LONG NONCODING; RNA, NEOPLASM; SIGNAL TRANSDUCTION;

EID: 84938412183     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.05.016     Document Type: Article

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