메뉴 건너뛰기




Volumn 71, Issue 23, 2011, Pages 7226-7237

STAT3 is necessary for proliferation and survival in colon cancer-initiating cells

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; CD133 ANTIGEN; DOXORUBICIN; FLUOROURACIL; INTERLEUKIN 6; LLL 12; PROTEINASE INHIBITOR; SHORT HAIRPIN RNA; STAT3 PROTEIN; STATTIC; UNCLASSIFIED DRUG;

EID: 82655189564     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-4660     Document Type: Article
Times cited : (256)

References (42)
  • 3
    • 23444452377 scopus 로고    scopus 로고
    • Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors
    • DOI 10.1136/jcp.2004.023416
    • Kusaba T, Nakayama T, Yamazumi K, Yakata Y, Yoshizaki A, Nagayasu T, et al. Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors. J Clin Pathol 2005;58:833-8. (Pubitemid 41113390)
    • (2005) Journal of Clinical Pathology , vol.58 , Issue.8 , pp. 833-838
    • Kusaba, T.1    Nakayama, T.2    Yamazumi, K.3    Yakata, Y.4    Yoshizaki, A.5    Nagayasu, T.6    Sekine, I.7
  • 5
    • 40149094813 scopus 로고    scopus 로고
    • Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells
    • DOI 10.1593/neo.07971
    • Xiong H, Zhang Z, Tian X, Sun D, Liang Q, Zhang Y, et al. Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. Neoplasia 2008;10:287-97. (Pubitemid 351328587)
    • (2008) Neoplasia , vol.10 , Issue.3 , pp. 287-297
    • Xiong, H.1    Zhang, Z.-G.2    Tian, X.-Q.3    Sun, D.-F.4    Liang, Q.-C.5    Zhang, Y.-J.6    Lu, R.7    Chen, Y.-X.8    Fang, J.-Y.9
  • 6
    • 34247281958 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction
    • DOI 10.1593/neo.06820
    • Tsareva S, Moriggl R, Corvinus F, Wiederanders B, Schütz A, Kovacic B, et al. Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction. Neoplasia 2007;9:279-91. (Pubitemid 46608295)
    • (2007) Neoplasia , vol.9 , Issue.4 , pp. 279-291
    • Tsareva, S.A.1    Moriggl, R.2    Corvinus, F.M.3    Wiederanders, B.4    Schutz, A.5    Kovacic, B.6    Friedrich, K.7
  • 7
    • 45549096766 scopus 로고    scopus 로고
    • Cancer stem cells: A step toward the cure
    • Boman BM, Wicha MS. Cancer stem cells: a step toward the cure. J Clin Oncol 2008;26:2795-9.
    • (2008) J Clin Oncol , vol.26 , pp. 2795-2799
    • Boman, B.M.1    Wicha, M.S.2
  • 8
    • 45549085634 scopus 로고    scopus 로고
    • Human colon cancer stem cells: A new paradigm in gastrointestinal oncology
    • Boman BM, Huang E. Human colon cancer stem cells: a new paradigm in gastrointestinal oncology. J Clin Oncol 2008;26:2828-38.
    • (2008) J Clin Oncol , vol.26 , pp. 2828-2838
    • Boman, B.M.1    Huang, E.2
  • 10
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • DOI 10.1038/nature05372, PII NATURE05372
    • O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007;445:106-10. (Pubitemid 46067310)
    • (2007) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 12
    • 0030024868 scopus 로고    scopus 로고
    • Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer
    • Magni M, Shammah S, Schiro R, Mellado W, Dalla-Favera R, Gianni AM. Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer. Blood 1996;87:1097-103. (Pubitemid 26043537)
    • (1996) Blood , vol.87 , Issue.3 , pp. 1097-1103
    • Magni, M.1    Shammah, S.2    Schiro, R.3    Mellado, W.4    Dalla-Favera, R.5    Gianni, A.M.6
  • 15
    • 60549111070 scopus 로고    scopus 로고
    • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
    • Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, Finetti P, et al. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 2009;69:1302-13.
    • (2009) Cancer Res , vol.69 , pp. 1302-1313
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3    Wicinski, J.4    Cervera, N.5    Finetti, P.6
  • 16
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 2009;69:3382-9.
    • (2009) Cancer Res , vol.69 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3    Ginestier, C.4    Dontu, G.5    Appelman, H.6
  • 17
    • 73949111590 scopus 로고    scopus 로고
    • A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppresive activity in human cancer cells
    • Lin L, Hutzen B, Li P, Ball S, Zuo M, DeAngelis S, et al. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppresive activity in human cancer cells. Neoplasia 2010;12:39-50.
    • (2010) Neoplasia , vol.12 , pp. 39-50
    • Lin, L.1    Hutzen, B.2    Li, P.3    Ball, S.4    Zuo, M.5    DeAngelis, S.6
  • 18
    • 33750982120 scopus 로고    scopus 로고
    • Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization
    • DOI 10.1016/j.chembiol.2006.09.018, PII S1074552106003784
    • Schust J, Sperl B, Hollis A, Mayer TU, Berg T. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chem Biol 2006;13:1235-42. (Pubitemid 44750735)
    • (2006) Chemistry and Biology , vol.13 , Issue.11 , pp. 1235-1242
    • Schust, J.1    Sperl, B.2    Hollis, A.3    Mayer, T.U.4    Berg, T.5
  • 19
    • 75149195336 scopus 로고    scopus 로고
    • The transcriptional network for mesenchymal transformation of brain tumours
    • Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, et al. The transcriptional network for mesenchymal transformation of brain tumours. Nature 2010;463:318-25.
    • (2010) Nature , vol.463 , pp. 318-325
    • Carro, M.S.1    Lim, W.K.2    Alvarez, M.J.3    Bollo, R.J.4    Zhao, X.5    Snyder, E.Y.6
  • 21
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 2002;8:945-54. (Pubitemid 35177340)
    • (2002) Clinical Cancer Research , vol.8 , Issue.4 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 22
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: Novel molecular targets for cancer drug discovery
    • DOI 10.1038/sj.onc.1204086
    • Turkson J, Jove R. STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 2000;19:6613-26. (Pubitemid 32197700)
    • (2000) Oncogene , vol.19 , Issue.56 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 23
    • 0029960028 scopus 로고    scopus 로고
    • Dominant negative Stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction
    • DOI 10.1074/jbc.271.11.5961
    • Kaptein A, Paillard V, Saunders M. Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. J Biol Chem 1996;271:5961-4. (Pubitemid 26095392)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.11 , pp. 5961-5964
    • Kaptein, A.1    Paillard, V.2    Saunders, M.3
  • 28
    • 37349098725 scopus 로고    scopus 로고
    • Autocrine IL-6 Signaling: A Key Event in Tumorigenesis?
    • DOI 10.1016/j.ccr.2007.12.020, PII S1535610807003790
    • Grivennikov S, Karin M. Autocrine IL-6 signaling: a key event in tumorigenesis? Cancer Cell 2008;13:7-9. (Pubitemid 350309747)
    • (2008) Cancer Cell , vol.13 , Issue.1 , pp. 7-9
    • Grivennikov, S.1    Karin, M.2
  • 29
    • 55349104462 scopus 로고    scopus 로고
    • Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner
    • Studebaker AW, Storci G, Werbeck JL, Sansone P, Sasser AK, Tavolari S, et al. Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner. Cancer Res 2008;68:9087-95.
    • (2008) Cancer Res , vol.68 , pp. 9087-9095
    • Studebaker, A.W.1    Storci, G.2    Werbeck, J.L.3    Sansone, P.4    Sasser, A.K.5    Tavolari, S.6
  • 32
    • 16844368861 scopus 로고    scopus 로고
    • Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice
    • DOI 10.1158/0008-5472.CAN-04-2425
    • Ling X, Arlinghaus RB. Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice. Cancer Res 2005;65:2532-6. (Pubitemid 40490046)
    • (2005) Cancer Research , vol.65 , Issue.7 , pp. 2532-2536
    • Ling, X.1    Arlinghaus, R.B.2
  • 33
    • 58149267888 scopus 로고    scopus 로고
    • LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
    • Fuh B, Sobo M, Cen L, Josiah D, Hutzen B, Cisek K, et al. LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model. Br J Cancer 2009;100:106-12.
    • (2009) Br J Cancer , vol.100 , pp. 106-112
    • Fuh, B.1    Sobo, M.2    Cen, L.3    Josiah, D.4    Hutzen, B.5    Cisek, K.6
  • 35
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong Z, Wen Z, Darnell JE Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994;264:95-8. (Pubitemid 24144493)
    • (1994) Science , vol.264 , Issue.5155 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3
  • 36
    • 58649108302 scopus 로고    scopus 로고
    • IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
    • Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 2009;15:103-13.
    • (2009) Cancer Cell , vol.15 , pp. 103-113
    • Grivennikov, S.1    Karin, E.2    Terzic, J.3    Mucida, D.4    Yu, G.Y.5    Vallabhapurapu, S.6
  • 37
    • 58649101347 scopus 로고    scopus 로고
    • gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
    • Bollrath J, Phesse T, von Burstin V, Putoczki T, Bennecke M, Bateman T, et al. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 2009;15:79-80.
    • (2009) Cancer Cell , vol.15 , pp. 79-80
    • Bollrath, J.1    Phesse, T.2    Von Burstin, V.3    Putoczki, T.4    Bennecke, M.5    Bateman, T.6
  • 39
    • 35748946958 scopus 로고    scopus 로고
    • Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo
    • Gharavi NM, Alva JA, Mouillesseaux KP, Lai C, Yeh M, Yeung W, et al. Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo. J Biol Chem 2007;282:1460-8.
    • (2007) J Biol Chem , vol.282 , pp. 1460-1468
    • Gharavi, N.M.1    Alva, J.A.2    Mouillesseaux, K.P.3    Lai, C.4    Yeh, M.5    Yeung, W.6
  • 40
    • 76649113726 scopus 로고    scopus 로고
    • CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
    • Ginestier C, Liu S, Diebel ME, Korkaya H, Luo M, Brown M, et al. CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. J Clin Invest 2010;120:485-97.
    • (2010) J Clin Invest , vol.120 , pp. 485-497
    • Ginestier, C.1    Liu, S.2    Diebel, M.E.3    Korkaya, H.4    Luo, M.5    Brown, M.6
  • 41
    • 70350212976 scopus 로고    scopus 로고
    • STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells
    • Sherry MM, Reeves A, Wu JK, Cochran BH. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells 2009;27:2383-92.
    • (2009) Stem Cells , vol.27 , pp. 2383-2392
    • Sherry, M.M.1    Reeves, A.2    Wu, J.K.3    Cochran, B.H.4
  • 42
    • 70350223977 scopus 로고    scopus 로고
    • Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth
    • Wang H, Lathia JD, Wu Q, Wang J, Li Z, Heddleston JM, et al. Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem Cells 2009;27:2393-404.
    • (2009) Stem Cells , vol.27 , pp. 2393-2404
    • Wang, H.1    Lathia, J.D.2    Wu, Q.3    Wang, J.4    Li, Z.5    Heddleston, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.