Preconditioning with tauroursodeoxycholic acid protects against contrast-induced HK-2 cell apoptosis by inhibiting endoplasmic reticulum stress

Angiology

Volumn 66, Issue 10, 2015, Pages 941-949

  Peng, Pingan ^a   Ma, Qian ^a   Wang, Le ^a   Zhang, Ou ^a   Han, Hongya ^a   Liu, Xiaoli ^a   Zhou, Yujie ^a   Zhao, Yingxin ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; contrast media; contrast induced acute kidney injury; endoplasmic reticulum stress; tauroursodeoxycholic acid

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 12; GLUCOSE REGULATED PROTEIN 78; MEGLUMINE DIATRIZOATE; MESSENGER RNA; TAUROURSODEOXYCHOLIC ACID; TUNICAMYCIN; ATF4 PROTEIN, HUMAN; CASP12 PROTEIN, HUMAN; CONTRAST MEDIUM; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; PROTECTIVE AGENT; TAUROCHENODEOXYCHOLIC ACID;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CLINICAL EVALUATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; ISCHEMIC PRECONDITIONING; KIDNEY TUBULE CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RENAL PROTECTION; STAINING; WESTERN BLOTTING; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; ENDOPLASMIC RETICULUM; EPITHELIUM CELL; GENETICS; KIDNEY PROXIMAL TUBULE; METABOLISM; PATHOLOGY; TIME;

ACTIVATING TRANSCRIPTION FACTOR 4; APOPTOSIS; CASPASE 12; CELL LINE; CONTRAST MEDIA; CYTOPROTECTION; DIATRIZOATE MEGLUMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; EPITHELIAL CELLS; HEAT-SHOCK PROTEINS; HUMANS; KIDNEY TUBULES, PROXIMAL; PROTECTIVE AGENTS; RNA, MESSENGER; TAUROCHENODEOXYCHOLIC ACID; TIME FACTORS;

EID: 84943537276     PISSN: 00033197     EISSN: 19401574     Source Type: Journal    
DOI: 10.1177/0003319715575965     Document Type: Article

References (47)

1. James MT, Samuel SM, Manning MA, et al. Contrast-induced acute kidney injury and risk of adverse clinical outcomes after coronary angiography: a systematic review and meta-analysis. Circ Cardiovasc Interv. 2013; 6 (1): 37-43.
2. Katsiki N, Athyros VG, Karagiannis A, Mikhailidis DP,. Contrast-Induced Nephropathy: An "All or None" Phenomenon? Angiology. 2014. doi: 10.1177/0003319714550309.
3. Watabe H, Sato A, Hoshi T, et al. Association of contrast-induced acute kidney injury with long-term cardiovascular events in acute coronary syndrome patients with chronic kidney disease undergoing emergent percutaneous coronary intervention. Int J Cardiol. 2014; 174 (1): 57-63.
4. Kim JH, Yang JH, Choi SH, et al. Predictors of outcomes of contrast-induced acute kidney injury after percutaneous coronary intervention in patients with chronic kidney disease. Am J Cardiol. 2014; 114 (12): 1830-1835.
5. Lameire N, Kellum JA, KDIGO AKI Guideline Work Group. Contrast-induced acute kidney injury and renal support for acute kidney injury: a KDIGO summary (Part 2). Crit Care. 2013; 17 (1): 205.
6. Cigarroa RG, Lange RA, Williams RH, Hillis LD,. Dosing of contrast material to prevent contrast nephropathy in patients with renal disease. Am J Med. 1989; 86 (6 pt 1): 649-652.
7. Investigators ACT,. Acetylcysteine for prevention of renal outcomes in patients undergoing coronary and peripheral vascular angiography: main results from the randomized Acetylcysteine for Contrast-induced nephropathy Trial (ACT). Circulation. 2011; 124 (11): 1250-1259.
8. Wu H, Li D, Fang M, Han H, Wang H,. Meta-analysis of short-term high versus low doses of atorvastatin preventing contrast-induced acute kidney injury in patients undergoing coronary angiography/percutaneous coronary intervention. J Clin Pharmacol. 2015; 55 (2): 123-131.
9. Kelly AM, Dwamena B, Cronin P, Bernstein SJ, Carlos RC,. Meta-analysis: effectiveness of drugs for preventing contrast-induced nephropathy. Ann Intern Med. 2008; 148 (4): 284-294.
10. Mikhailidis DP, Athyros VG,. Acute kidney injury: Short-term statin therapy for prevention of contrast-induced AKI. Nat Rev Nephrol. 2014; 10 (1): 8-9.
11. Kitamura M., Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces. Am J Physiol Renal Physiol. 2008; 295 (2): F323-334.
12. Sozen E, Karademir B, Ozer NK,. Basic mechanisms in endoplasmic reticulum stress and relation to cardiovascular diseases. Free Radic Biol Med. 2014; 78C: 30-41.
13. Inagi R,. Endoplasmic reticulum stress as a progression factor for kidney injury. Curr Opin Pharmacol. 2010; 10 (2): 156-165.
14. Romano G, Briguori C, Quintavalle C, et al. Contrast agents and renal cell apoptosis. Eur Heart J. 2008; 29 (20): 2569-2576.
15. Ueda N, Kaushal GP, Shah SV,. Apoptotic mechanisms in acute renal failure. Am J Med. 2000; 108 (5): 403-415.
16. Xiong XL, Jia RH, Yang DP, Ding GH,. Irbesartan attenuates contrast media-induced NRK-52E cells apoptosis. Pharmacol Res. 2006; 54 (4): 253-260.
17. Wu CT, Sheu ML, Tsai KS, Weng TI, Chiang CK, Liu SH,. The role of endoplasmic reticulum stress-related unfolded protein response in the radiocontrast medium-induced renal tubular cell injury. Toxicol Sci. 2010; 114 (2): 295-301.
18. Yang Y, Yang D, Yang D, Jia R, Ding G,. Role of reactive oxygen species-mediated endoplasmic reticulum stress in contrast-induced renal tubular cell apoptosis. Nephron Exp Nephrol. 2014; 128 (1-2): 30-36.
19. Gorman AM, Healy SJ, Jager R, Samali A,. Stress management at the ER: regulators of ER stress-induced apoptosis. Pharmacol Ther. 2012; 134 (3): 306-316.
20. Andreucci M, Faga T, Russo D, et al. Differential activation of signaling pathways by low-osmolar and iso-osmolar radiocontrast agents in human renal tubular cells. J Cell Biochem. 2014; 115 (2): 281-289.
21. Andreucci M, Lucisano G, Faga T, et al. Differential activation of signaling pathways involved in cell death, survival and inflammation by radiocontrast media in human renal proximal tubular cells. Toxicol Sci. 2011; 119 (2): 408-416.
22. Gao X, Fu L, Xiao M, et al. The nephroprotective effect of tauroursodeoxycholic acid on ischaemia/reperfusion-induced acute kidney injury by inhibiting endoplasmic reticulum stress. Basic Clin Pharmacol Toxicol. 2012; 111 (1): 14-23.
23. Tehrani S, Laing C, Yellon DM, Hausenloy DJ,. Contrast-induced acute kidney injury following PCI. Eur J Clin Invest. 2013; 43 (5): 483-490.
24. Goldenberg I, Matetzky S,. Nephropathy induced by contrast media: pathogenesis, risk factors and preventive strategies. CMAJ. 2005; 172 (11): 1461-1471.
25. Goldfarb S, Spinler S, Berns JS, Rudnick MR,. Low-osmolality contrast media and the risk of contrast-associated nephrotoxicity. Invest Radiol. 1993; 28 (suppl 5): S7-10; discussion S11-S12.
26. Barrett BJ, Carlisle EJ,. Metaanalysis of the relative nephrotoxicity of high- and low-osmolality iodinated contrast media. Radiology. 1993; 188 (1): 171-178.
27. Dong M, Jiao Z, Liu T, Guo F, Li G,. Effect of administration route on the renal safety of contrast agents: a meta-analysis of randomized controlled trials. J Nephrol. 2012; 25 (3): 290-301.
28. Reed M, Meier P, Tamhane UU, Welch KB, Moscucci M, Gurm HS,. The relative renal safety of iodixanol compared with low-osmolar contrast media: a meta-analysis of randomized controlled trials. JACC Cardiovasc Interv. 2009; 2 (7): 645-654.
29. Bolognese L, Falsini G, Schwenke C, et al. Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast Media and Nephrotoxicity Following Primary Angioplasty for Acute Myocardial Infarction [CONTRAST-AMI] Trial). Am J Cardiol. 2012; 109 (1): 67-74.
30. Heinrich MC, Haberle L, Muller V, Bautz W, Uder M,. Nephrotoxicity of iso-osmolar iodixanol compared with nonionic low-osmolar contrast media: meta-analysis of randomized controlled trials. Radiology. 2009; 250 (1): 68-86.
31. Stratta P, Quaglia M, Airoldi A, Aime S,. Structure-function relationships of iodinated contrast media and risk of nephrotoxicity. Curr Med Chem. 2012; 19 (5): 736-743.
32. Battenfeld R, Khater Ae-R, Drommer W, Guenzel P, Kaup FJ,. Ioxaglate-induced light and electron microscopic alterations in the renal proximal tubular epithelium of rats. Invest Radiol. 1991; 26 (1): 35-39.
33. Ueda J, Nygren A, Hansell P, Ulfendahl HR,. Effect of intravenous contrast media on proximal and distal tubular hydrostatic pressure in the rat kidney. Acta Radiol. 1993; 34 (1): 83-87.
34. Quintavalle C, Brenca M, De Micco F, et al. In vivo and in vitro assessment of pathways involved in contrast media-induced renal cells apoptosis. Cell Death Dis. 2011; 2: e155.
35. Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 2006; 313 (5790): 1137-1140.
36. Chen Y, Liu CP, Xu KF, et al. Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes. Am J Nephrol. 2008; 28 (6): 1014-1022.
37. Xie Q, Khaoustov VI, Chung CC, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002; 36 (3): 592-601.
38. Groenendyk J, Sreenivasaiah PK, Kim do H, Agellon LB, Michalak M,. Biology of endoplasmic reticulum stress in the heart. Circ Res. 2010; 107 (10): 1185-1197.
39. Lakshmanan AP, Thandavarayan RA, Palaniyandi SS, et al. Modulation of AT-1R/CHOP-JNK-Caspase12 pathway by olmesartan treatment attenuates ER stress-induced renal apoptosis in streptozotocin-induced diabetic mice. Eur J Pharm Sci. 2011; 44 (5): 627-634.
40. Orrenius S, Zhivotovsky B, Nicotera P,. Regulation of cell death: the calcium-apoptosis link. Nat Rev Mol Cell Biol. 2003; 4 (7): 552-565.
41. Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y,. An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem. 2002; 277 (37): 34287-34294.
42. Ding W, Yang L, Zhang M, Gu Y,. Reactive oxygen species-mediated endoplasmic reticulum stress contributes to aldosterone-induced apoptosis in tubular epithelial cells. Biochem Biophys Res Commun. 2012; 418 (3): 451-456.
43. Chen S, He FF, Wang H, et al. Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes. Cell Calcium. 2011; 50 (6): 523-529.
44. Pan XL, Zhao L, Li L, et al. Efficacy and safety of tauroursodeoxycholic acid in the treatment of liver cirrhosis: a double-blind randomized controlled trial. J Huazhong Univ Sci Technolog Med Sci. 2013; 33 (2): 189-194.
45. Crosignani A, Battezzati PM, Setchell KD, et al. Tauroursodeoxycholic acid for treatment of primary biliary cirrhosis. A dose-response study. Dig Dis Sci. 1996; 41 (4): 809-815.
46. Kars M, Yang L, Gregor MF, et al. Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes. 2010; 59 (8): 1899-1905.
47. Obici L, Cortese A, Lozza A, et al. Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study. Amyloid. 2012; 19 (Suppl 1): 34-36.