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Volumn 11, Issue 9, 2015, Pages

Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN E2; T LYMPHOCYTE RECEPTOR; GLYCOPROTEIN E2, HEPATITIS C VIRUS; LYMPHOCYTE ANTIGEN RECEPTOR; VIRUS ENVELOPE PROTEIN; VIRUS RNA;

EID: 84943516708     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005183     Document Type: Article
Times cited : (24)

References (60)
  • 1
    • 84880276248 scopus 로고    scopus 로고
    • Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
    • Rehermann B, (2013) Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells. Nat Med 19: 859–868. doi: 10.1038/nm.3251 23836236
    • (2013) Nat Med , vol.19 , pp. 859-868
    • Rehermann, B.1
  • 2
    • 68849111675 scopus 로고    scopus 로고
    • Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence
    • Rehermann B, (2009) Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence. J Clin Invest 119: 1745–1754. doi: 10.1172/JCI39133 19587449
    • (2009) J Clin Invest , vol.119 , pp. 1745-1754
    • Rehermann, B.1
  • 3
    • 84889885286 scopus 로고    scopus 로고
    • Subinfectious hepatitis C virus exposures suppress T cell responses against subsequent acute infection
    • Park SH, Veerapu NS, Shin EC, Biancotto A, McCoy JP, et al. (2013) Subinfectious hepatitis C virus exposures suppress T cell responses against subsequent acute infection. Nat Med 19: 1638–1642. doi: 10.1038/nm.3408 24270546
    • (2013) Nat Med , vol.19 , pp. 1638-1642
    • Park, S.H.1    Veerapu, N.S.2    Shin, E.C.3    Biancotto, A.4    McCoy, J.P.5
  • 4
    • 0037105567 scopus 로고    scopus 로고
    • Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
    • Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, et al. (2002) Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 169: 3447–3458. 12218168
    • (2002) J Immunol , vol.169 , pp. 3447-3458
    • Wedemeyer, H.1    He, X.S.2    Nascimbeni, M.3    Davis, A.R.4    Greenberg, H.B.5
  • 5
    • 0035000769 scopus 로고    scopus 로고
    • Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus
    • Gruener NH, Lechner F, Jung MC, Diepolder H, Gerlach T, et al. (2001) Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus. J Virol 75: 5550–5558. 11356962
    • (2001) J Virol , vol.75 , pp. 5550-5558
    • Gruener, N.H.1    Lechner, F.2    Jung, M.C.3    Diepolder, H.4    Gerlach, T.5
  • 7
    • 0037337996 scopus 로고    scopus 로고
    • The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection
    • Freeman AJ, Pan Y, Harvey CE, Post JJ, Law MG, et al. (2003) The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection. J Hepatol 38: 349–356. 12586302
    • (2003) J Hepatol , vol.38 , pp. 349-356
    • Freeman, A.J.1    Pan, Y.2    Harvey, C.E.3    Post, J.J.4    Law, M.G.5
  • 8
    • 0142155578 scopus 로고    scopus 로고
    • Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers
    • Day CL, Seth NP, Lucas M, Appel H, Gauthier L, et al. (2003) Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J Clin Invest 112: 831–842. 12975468
    • (2003) J Clin Invest , vol.112 , pp. 831-842
    • Day, C.L.1    Seth, N.P.2    Lucas, M.3    Appel, H.4    Gauthier, L.5
  • 9
    • 0142178211 scopus 로고    scopus 로고
    • HCV persistence and immune evasion in the absence of memory T cell help
    • Grakoui A, Shoukry NH, Woollard DJ, Han JH, Hanson HL, et al. (2003) HCV persistence and immune evasion in the absence of memory T cell help. Science 302: 659–662. 14576438
    • (2003) Science , vol.302 , pp. 659-662
    • Grakoui, A.1    Shoukry, N.H.2    Woollard, D.J.3    Han, J.H.4    Hanson, H.L.5
  • 10
    • 17644444485 scopus 로고    scopus 로고
    • Analysis of successful immune responses in persons infected with hepatitis C virus
    • Lechner F, Wong DK, Dunbar PR, Chapman R, Chung RT, et al. (2000) Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med 191: 1499–1512. 10790425
    • (2000) J Exp Med , vol.191 , pp. 1499-1512
    • Lechner, F.1    Wong, D.K.2    Dunbar, P.R.3    Chapman, R.4    Chung, R.T.5
  • 11
    • 23944467250 scopus 로고    scopus 로고
    • Adaptive immune responses in acute and chronic hepatitis C virus infection
    • Bowen DG, Walker CM, (2005) Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 436: 946–952. 16107834
    • (2005) Nature , vol.436 , pp. 946-952
    • Bowen, D.G.1    Walker, C.M.2
  • 12
    • 0028837677 scopus 로고
    • Immunosuppression induced by hepatitis C virus infection reduces acute renal-transplant rejection
    • Corell A, Morales JM, Mandrono A, Munoz MA, Andres A, et al. (1995) Immunosuppression induced by hepatitis C virus infection reduces acute renal-transplant rejection. Lancet 346: 1497–1498. 7491027
    • (1995) Lancet , vol.346 , pp. 1497-1498
    • Corell, A.1    Morales, J.M.2    Mandrono, A.3    Munoz, M.A.4    Andres, A.5
  • 13
    • 79954608578 scopus 로고    scopus 로고
    • Impaired hepatitis B vaccine responses during chronic hepatitis C infection: involvement of the PD-1 pathway in regulating CD4(+) T cell responses
    • Moorman JP, Zhang CL, Ni L, Ma CJ, Zhang Y, et al. (2011) Impaired hepatitis B vaccine responses during chronic hepatitis C infection: involvement of the PD-1 pathway in regulating CD4(+) T cell responses. Vaccine 29: 3169–3176. doi: 10.1016/j.vaccine.2011.02.052 21376795
    • (2011) Vaccine , vol.29 , pp. 3169-3176
    • Moorman, J.P.1    Zhang, C.L.2    Ni, L.3    Ma, C.J.4    Zhang, Y.5
  • 14
    • 84892758835 scopus 로고    scopus 로고
    • KLRG1 impairs CD4+ T cell responses via p16ink4a and p27kip1 pathways: role in hepatitis B vaccine failure in individuals with hepatitis C virus infection
    • Shi L, Wang JM, Ren JP, Cheng YQ, Ying RS, et al. (2014) KLRG1 impairs CD4+ T cell responses via p16ink4a and p27kip1 pathways: role in hepatitis B vaccine failure in individuals with hepatitis C virus infection. J Immunol 192: 649–657. doi: 10.4049/jimmunol.1302069 24337749
    • (2014) J Immunol , vol.192 , pp. 649-657
    • Shi, L.1    Wang, J.M.2    Ren, J.P.3    Cheng, Y.Q.4    Ying, R.S.5
  • 15
    • 84881400770 scopus 로고    scopus 로고
    • Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells
    • Ramakrishnaiah V, Thumann C, Fofana I, Habersetzer F, Pan Q, et al. (2013) Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells. Proc Natl Acad Sci U S A 110: 13109–13113. doi: 10.1073/pnas.1221899110 23878230
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 13109-13113
    • Ramakrishnaiah, V.1    Thumann, C.2    Fofana, I.3    Habersetzer, F.4    Pan, Q.5
  • 16
    • 84894048545 scopus 로고    scopus 로고
    • HCV transmission by hepatic exosomes establishes a productive infection
    • Cosset FL, Dreux M, (2014) HCV transmission by hepatic exosomes establishes a productive infection. J Hepatol 60: 674–675. doi: 10.1016/j.jhep.2013.10.015 24512825
    • (2014) J Hepatol , vol.60 , pp. 674-675
    • Cosset, F.L.1    Dreux, M.2
  • 18
    • 84908349078 scopus 로고    scopus 로고
    • Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90
    • Bukong TN, Momen-Heravi F, Kodys K, Bala S, Szabo G, (2014) Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90. PLoS Pathog 10: e1004424. doi: 10.1371/journal.ppat.1004424 25275643
    • (2014) PLoS Pathog , vol.10 , pp. 1004424
    • Bukong, T.N.1    Momen-Heravi, F.2    Kodys, K.3    Bala, S.4    Szabo, G.5
  • 19
    • 84867653559 scopus 로고    scopus 로고
    • Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity
    • Dreux M, Garaigorta U, Boyd B, Decembre E, Chung J, et al. (2012) Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity. Cell Host Microbe 12: 558–570. doi: 10.1016/j.chom.2012.08.010 23084922
    • (2012) Cell Host Microbe , vol.12 , pp. 558-570
    • Dreux, M.1    Garaigorta, U.2    Boyd, B.3    Decembre, E.4    Chung, J.5
  • 20
    • 84882756430 scopus 로고    scopus 로고
    • Cross-linking of CD81 by HCV-E2 protein inhibits human intrahepatic plasmacytoid dendritic cells response to CpG-ODN
    • Tu Z, Zhang P, Li H, Niu J, Jin X, et al. (2013) Cross-linking of CD81 by HCV-E2 protein inhibits human intrahepatic plasmacytoid dendritic cells response to CpG-ODN. Cell Immunol 284: 98–103. doi: 10.1016/j.cellimm.2013.07.012 23954883
    • (2013) Cell Immunol , vol.284 , pp. 98-103
    • Tu, Z.1    Zhang, P.2    Li, H.3    Niu, J.4    Jin, X.5
  • 21
    • 0030982254 scopus 로고    scopus 로고
    • Distribution of hepatitis C virus (HCV) RNA in whole blood and blood cell fractions: plasma HCV RNA analysis underestimates circulating virus load
    • Schmidt WN, Wu P, Han JQ, Perino MJ, LaBrecque DR, et al. (1997) Distribution of hepatitis C virus (HCV) RNA in whole blood and blood cell fractions: plasma HCV RNA analysis underestimates circulating virus load. J Infect Dis 176: 20–26. 9207345
    • (1997) J Infect Dis , vol.176 , pp. 20-26
    • Schmidt, W.N.1    Wu, P.2    Han, J.Q.3    Perino, M.J.4    LaBrecque, D.R.5
  • 22
    • 0026743931 scopus 로고
    • Detection of replicative form of hepatitis C virus RNA in peripheral blood mononuclear cells
    • Wang JT, Sheu JC, Lin JT, Wang TH, Chen DS, (1992) Detection of replicative form of hepatitis C virus RNA in peripheral blood mononuclear cells. J Infect Dis 166: 1167–1169. 1328405
    • (1992) J Infect Dis , vol.166 , pp. 1167-1169
    • Wang, J.T.1    Sheu, J.C.2    Lin, J.T.3    Wang, T.H.4    Chen, D.S.5
  • 23
    • 34948827431 scopus 로고    scopus 로고
    • Hepatitis C virus lymphotropism: lessons from a decade of studies
    • Zignego AL, Giannini C, Monti M, Gragnani L, (2007) Hepatitis C virus lymphotropism: lessons from a decade of studies. Dig Liver Dis 39 Suppl 1: S38–45. 17936221
    • (2007) Dig Liver Dis , vol.39 , pp. 38-45
    • Zignego, A.L.1    Giannini, C.2    Monti, M.3    Gragnani, L.4
  • 24
    • 84861321809 scopus 로고    scopus 로고
    • Hepatitis C virus infection of human T lymphocytes is mediated by CD5
    • Sarhan MA, Pham TN, Chen AY, Michalak TI, (2012) Hepatitis C virus infection of human T lymphocytes is mediated by CD5. J Virol 86: 3723–3735. doi: 10.1128/JVI.06956-11 22278227
    • (2012) J Virol , vol.86 , pp. 3723-3735
    • Sarhan, M.A.1    Pham, T.N.2    Chen, A.Y.3    Michalak, T.I.4
  • 25
    • 0033178877 scopus 로고    scopus 로고
    • Replication of hepatitis C virus in B lymphocytes (CD19+)
    • Morsica G, Tambussi G, Sitia G, Novati R, Lazzarin A, et al. (1999) Replication of hepatitis C virus in B lymphocytes (CD19+). Blood 94: 1138–1139. 10454799
    • (1999) Blood , vol.94 , pp. 1138-1139
    • Morsica, G.1    Tambussi, G.2    Sitia, G.3    Novati, R.4    Lazzarin, A.5
  • 26
    • 33745880701 scopus 로고    scopus 로고
    • Extrahepatic replication of HCV: insights into clinical manifestations and biological consequences
    • Blackard JT, Kemmer N, Sherman KE, (2006) Extrahepatic replication of HCV: insights into clinical manifestations and biological consequences. Hepatology 44: 15–22. 16799966
    • (2006) Hepatology , vol.44 , pp. 15-22
    • Blackard, J.T.1    Kemmer, N.2    Sherman, K.E.3
  • 27
    • 0030065866 scopus 로고    scopus 로고
    • Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells
    • Lerat H, Berby F, Trabaud MA, Vidalin O, Major M, et al. (1996) Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells. J Clin Invest 97: 845–851. 8609243
    • (1996) J Clin Invest , vol.97 , pp. 845-851
    • Lerat, H.1    Berby, F.2    Trabaud, M.A.3    Vidalin, O.4    Major, M.5
  • 28
    • 39749128562 scopus 로고    scopus 로고
    • Hepatitis C virus replicates in the same immune cell subsets in chronic hepatitis C and occult infection
    • Pham TN, King D, Macparland SA, McGrath JS, Reddy SB, et al. (2008) Hepatitis C virus replicates in the same immune cell subsets in chronic hepatitis C and occult infection. Gastroenterology 134: 812–822. doi: 10.1053/j.gastro.2007.12.011 18243182
    • (2008) Gastroenterology , vol.134 , pp. 812-822
    • Pham, T.N.1    King, D.2    Macparland, S.A.3    McGrath, J.S.4    Reddy, S.B.5
  • 29
    • 0032191163 scopus 로고    scopus 로고
    • Innate immune recognition and control of adaptive immune responses
    • Medzhitov R, Janeway CA, Jr. (1998) Innate immune recognition and control of adaptive immune responses. Semin Immunol 10: 351–353. 9799709
    • (1998) Semin Immunol , vol.10 , pp. 351-353
    • Medzhitov, R.1    Janeway, C.A.2
  • 30
    • 33845381987 scopus 로고    scopus 로고
    • A complete mutational fitness map of the hepatitis C virus nonstructural 3 protease: relation to recognition by cytotoxic T lymphocytes
    • Soderholm J, Sallberg M, (2006) A complete mutational fitness map of the hepatitis C virus nonstructural 3 protease: relation to recognition by cytotoxic T lymphocytes. J Infect Dis 194: 1724–1728. 17109345
    • (2006) J Infect Dis , vol.194 , pp. 1724-1728
    • Soderholm, J.1    Sallberg, M.2
  • 31
    • 44649102065 scopus 로고    scopus 로고
    • Unraveling the role of PD-1/PD-L interactions in persistent hepatotropic infections: potential for therapeutic application?
    • Radziewicz H, Hanson HL, Ahmed R, Grakoui A, (2008) Unraveling the role of PD-1/PD-L interactions in persistent hepatotropic infections: potential for therapeutic application? Gastroenterology 134: 2168–2171. doi: 10.1053/j.gastro.2008.04.012 18486616
    • (2008) Gastroenterology , vol.134 , pp. 2168-2171
    • Radziewicz, H.1    Hanson, H.L.2    Ahmed, R.3    Grakoui, A.4
  • 32
    • 84864503916 scopus 로고    scopus 로고
    • MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
    • Fabbri M, Paone A, Calore F, Galli R, Gaudio E, et al. (2012) MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc Natl Acad Sci U S A 109: E2110–2116. doi: 10.1073/pnas.1209414109 22753494
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 2110-2116
    • Fabbri, M.1    Paone, A.2    Calore, F.3    Galli, R.4    Gaudio, E.5
  • 33
    • 78650719213 scopus 로고    scopus 로고
    • Lck and the nature of the T cell receptor trigger
    • Davis SJ, van der Merwe PA, (2011) Lck and the nature of the T cell receptor trigger. Trends Immunol 32: 1–5. doi: 10.1016/j.it.2010.11.003 21190897
    • (2011) Trends Immunol , vol.32 , pp. 1-5
    • Davis, S.J.1    van der Merwe, P.A.2
  • 34
    • 52649145895 scopus 로고    scopus 로고
    • GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy
    • Xue Y, Ren J, Gao X, Jin C, Wen L, et al. (2008) GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics 7: 1598–1608. doi: 10.1074/mcp.M700574-MCP200 18463090
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1598-1608
    • Xue, Y.1    Ren, J.2    Gao, X.3    Jin, C.4    Wen, L.5
  • 35
    • 84879089779 scopus 로고    scopus 로고
    • GB virus C particles inhibit T cell activation via envelope E2 protein-mediated inhibition of TCR signaling
    • Bhattarai N, McLinden JH, Xiang J, Landay AL, Chivero ET, et al. (2013) GB virus C particles inhibit T cell activation via envelope E2 protein-mediated inhibition of TCR signaling. J Immunol 190: 6351–6359. doi: 10.4049/jimmunol.1300589 23686495
    • (2013) J Immunol , vol.190 , pp. 6351-6359
    • Bhattarai, N.1    McLinden, J.H.2    Xiang, J.3    Landay, A.L.4    Chivero, E.T.5
  • 36
    • 84885338088 scopus 로고    scopus 로고
    • PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors
    • Ahmed F, Kaundal R, Raghava GP, (2013) PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors. BMC Bioinformatics 14 Suppl 14: S9. doi: 10.1186/1471-2105-14-S14-S9 24267009
    • (2013) BMC Bioinformatics , vol.14 , pp. 9
    • Ahmed, F.1    Kaundal, R.2    Raghava, G.P.3
  • 37
    • 84856367312 scopus 로고    scopus 로고
    • Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex
    • Shimakami T, Yamane D, Jangra RK, Kempf BJ, Spaniel C, et al. (2012) Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proc Natl Acad Sci U S A 109: 941–946. doi: 10.1073/pnas.1112263109 22215596
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 941-946
    • Shimakami, T.1    Yamane, D.2    Jangra, R.K.3    Kempf, B.J.4    Spaniel, C.5
  • 39
    • 77649239548 scopus 로고    scopus 로고
    • Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems
    • Parameswaran P, Sklan E, Wilkins C, Burgon T, Samuel MA, et al. (2010) Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. PLoS Pathog 6: e1000764. doi: 10.1371/journal.ppat.1000764 20169186
    • (2010) PLoS Pathog , vol.6 , pp. 1000764
    • Parameswaran, P.1    Sklan, E.2    Wilkins, C.3    Burgon, T.4    Samuel, M.A.5
  • 40
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15–20. 15652477
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 41
    • 17444374230 scopus 로고    scopus 로고
    • Src kinase regulation by phosphorylation and dephosphorylation
    • Roskoski R, Jr. (2005) Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun 331: 1–14. 15845350
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 1-14
    • Roskoski, R.1
  • 42
    • 0037844867 scopus 로고    scopus 로고
    • Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells
    • Gil-Henn H, Elson A, (2003) Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells. J Biol Chem 278: 15579–15586. 12598528
    • (2003) J Biol Chem , vol.278 , pp. 15579-15586
    • Gil-Henn, H.1    Elson, A.2
  • 43
    • 70350091280 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase epsilon regulates integrin-mediated podosome stability in osteoclasts by activating Src
    • Granot-Attas S, Luxenburg C, Finkelshtein E, Elson A, (2009) Protein tyrosine phosphatase epsilon regulates integrin-mediated podosome stability in osteoclasts by activating Src. Mol Biol Cell 20: 4324–4334. doi: 10.1091/mbc.E08-11-1158 19692574
    • (2009) Mol Biol Cell , vol.20 , pp. 4324-4334
    • Granot-Attas, S.1    Luxenburg, C.2    Finkelshtein, E.3    Elson, A.4
  • 44
    • 0033539103 scopus 로고    scopus 로고
    • The transmembranal and cytoplasmic forms of protein tyrosine phosphatase epsilon physically associate with the adaptor molecule Grb2
    • Toledano-Katchalski H, Elson A, (1999) The transmembranal and cytoplasmic forms of protein tyrosine phosphatase epsilon physically associate with the adaptor molecule Grb2. Oncogene 18: 5024–5031. 10490839
    • (1999) Oncogene , vol.18 , pp. 5024-5031
    • Toledano-Katchalski, H.1    Elson, A.2
  • 45
    • 79960984904 scopus 로고    scopus 로고
    • Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex
    • Sharma S, Findlay GM, Bandukwala HS, Oberdoerffer S, Baust B, et al. (2011) Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proc Natl Acad Sci U S A 108: 11381–11386. doi: 10.1073/pnas.1019711108 21709260
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11381-11386
    • Sharma, S.1    Findlay, G.M.2    Bandukwala, H.S.3    Oberdoerffer, S.4    Baust, B.5
  • 47
    • 0031041141 scopus 로고    scopus 로고
    • Serum interleukin 4 and interleukin 10 levels in patients with chronic hepatitis C virus infection
    • Reiser M, Marousis CG, Nelson DR, Lauer G, Gonzalez-Peralta RP, et al. (1997) Serum interleukin 4 and interleukin 10 levels in patients with chronic hepatitis C virus infection. J Hepatol 26: 471–478. 9075651
    • (1997) J Hepatol , vol.26 , pp. 471-478
    • Reiser, M.1    Marousis, C.G.2    Nelson, D.R.3    Lauer, G.4    Gonzalez-Peralta, R.P.5
  • 48
    • 77953800164 scopus 로고    scopus 로고
    • Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection
    • Jang IK, Zhang J, Chiang YJ, Kole HK, Cronshaw DG, et al. (2010) Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection. Proc Natl Acad Sci U S A 107: 10620–10625. doi: 10.1073/pnas.0905039107 20498059
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10620-10625
    • Jang, I.K.1    Zhang, J.2    Chiang, Y.J.3    Kole, H.K.4    Cronshaw, D.G.5
  • 49
    • 38049141270 scopus 로고    scopus 로고
    • Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening
    • Supekova L, Supek F, Lee J, Chen S, Gray N, et al. (2008) Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening. J Biol Chem 283: 29–36. 17951261
    • (2008) J Biol Chem , vol.283 , pp. 29-36
    • Supekova, L.1    Supek, F.2    Lee, J.3    Chen, S.4    Gray, N.5
  • 50
    • 12144288288 scopus 로고    scopus 로고
    • Comparison of hepatitis C viral loads in patients with or without coinfection with different genotypes
    • Schijman A, Colina R, Mukomolov S, Kalinina O, Garcia L, et al. (2004) Comparison of hepatitis C viral loads in patients with or without coinfection with different genotypes. Clin Diagn Lab Immunol 11: 433–435. 15014001
    • (2004) Clin Diagn Lab Immunol , vol.11 , pp. 433-435
    • Schijman, A.1    Colina, R.2    Mukomolov, S.3    Kalinina, O.4    Garcia, L.5
  • 51
    • 0034964256 scopus 로고    scopus 로고
    • Comparison of hepatitis C viral loads in patients with or without human immunodeficiency virus
    • Matthews-Greer JM, Caldito GC, Adley SD, Willis R, Mire AC, et al. (2001) Comparison of hepatitis C viral loads in patients with or without human immunodeficiency virus. Clin Diagn Lab Immunol 8: 690–694. 11427412
    • (2001) Clin Diagn Lab Immunol , vol.8 , pp. 690-694
    • Matthews-Greer, J.M.1    Caldito, G.C.2    Adley, S.D.3    Willis, R.4    Mire, A.C.5
  • 52
    • 84900853251 scopus 로고    scopus 로고
    • Human pegivirus RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA-containing particles are infectious in vitro
    • Chivero ET, Bhattarai N, Rydze RT, Winters MA, Holodniy M, et al. (2014) Human pegivirus RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA-containing particles are infectious in vitro. J Gen Virol 95: 1307–1319. doi: 10.1099/vir.0.063016-0 24668525
    • (2014) J Gen Virol , vol.95 , pp. 1307-1319
    • Chivero, E.T.1    Bhattarai, N.2    Rydze, R.T.3    Winters, M.A.4    Holodniy, M.5
  • 53
    • 84876287430 scopus 로고    scopus 로고
    • A pathogenic picornavirus acquires an envelope by hijacking cellular membranes
    • Feng Z, Hensley L, McKnight KL, Hu F, Madden V, et al. (2013) A pathogenic picornavirus acquires an envelope by hijacking cellular membranes. Nature 496: 367–371. doi: 10.1038/nature12029 23542590
    • (2013) Nature , vol.496 , pp. 367-371
    • Feng, Z.1    Hensley, L.2    McKnight, K.L.3    Hu, F.4    Madden, V.5
  • 54
    • 33750589229 scopus 로고    scopus 로고
    • Impaired cytokine production and suppressed lymphocyte proliferation activity in HCV-infected cocaine and heroin ("speedball") users
    • Rios-Olivares E, Vila LM, Reyes JC, Rodriguez JW, Colon JH, et al. (2006) Impaired cytokine production and suppressed lymphocyte proliferation activity in HCV-infected cocaine and heroin ("speedball") users. Drug Alcohol Depend 85: 236–243. 16766138
    • (2006) Drug Alcohol Depend , vol.85 , pp. 236-243
    • Rios-Olivares, E.1    Vila, L.M.2    Reyes, J.C.3    Rodriguez, J.W.4    Colon, J.H.5
  • 55
    • 33745497485 scopus 로고    scopus 로고
    • Early impairment of hepatitis C virus specific T cell proliferation during acute infection leads to failure of viral clearance
    • Folgori A, Spada E, Pezzanera M, Ruggeri L, Mele A, et al. (2006) Early impairment of hepatitis C virus specific T cell proliferation during acute infection leads to failure of viral clearance. Gut 55: 1012–1019. 16484505
    • (2006) Gut , vol.55 , pp. 1012-1019
    • Folgori, A.1    Spada, E.2    Pezzanera, M.3    Ruggeri, L.4    Mele, A.5
  • 56
    • 0345188811 scopus 로고    scopus 로고
    • Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
    • Lohmann V, Korner F, Koch J, Herian U, Theilmann L, et al. (1999) Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285: 110–113. 10390360
    • (1999) Science , vol.285 , pp. 110-113
    • Lohmann, V.1    Korner, F.2    Koch, J.3    Herian, U.4    Theilmann, L.5
  • 57
    • 27144513392 scopus 로고    scopus 로고
    • Quantitative analysis of the hepatitis C virus replication complex
    • Quinkert D, Bartenschlager R, Lohmann V, (2005) Quantitative analysis of the hepatitis C virus replication complex. J Virol 79: 13594–13605. 16227280
    • (2005) J Virol , vol.79 , pp. 13594-13605
    • Quinkert, D.1    Bartenschlager, R.2    Lohmann, V.3
  • 59
    • 77958121295 scopus 로고    scopus 로고
    • GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates
    • Mohr EL, Xiang J, McLinden JH, Kaufman TM, Chang Q, et al. (2010) GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates. J Immunol 185: 4496–4505. doi: 10.4049/jimmunol.1001980 20826757
    • (2010) J Immunol , vol.185 , pp. 4496-4505
    • Mohr, E.L.1    Xiang, J.2    McLinden, J.H.3    Kaufman, T.M.4    Chang, Q.5
  • 60
    • 84861818951 scopus 로고    scopus 로고
    • Characterization of a peptide domain within the GB virus C envelope glycoprotein (E2) that inhibits HIV replication
    • Xiang J, McLinden JH, Kaufman TM, Mohr EL, Bhattarai N, et al. (2012) Characterization of a peptide domain within the GB virus C envelope glycoprotein (E2) that inhibits HIV replication. Virology 430: 53–62. doi: 10.1016/j.virol.2012.04.019 22608061
    • (2012) Virology , vol.430 , pp. 53-62
    • Xiang, J.1    McLinden, J.H.2    Kaufman, T.M.3    Mohr, E.L.4    Bhattarai, N.5


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