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Volumn 10, Issue 10, 2014, Pages

Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN E; ARGONAUTE 2 PROTEIN; BAFILOMYCIN A1; CD81 ANTIGEN; HEAT SHOCK PROTEIN 90; LACTATE DEHYDROGENASE; LANSOPRAZOLE; MICRORNA 122; TELAPREVIR; VIRUS RNA; ARGONAUTE PROTEIN; EIF2C2 PROTEIN, HUMAN; MICRORNA; MIRN122 MICRORNA, HUMAN; PROTEIN BINDING; VIRUS RECEPTOR;

EID: 84908349078     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004424     Document Type: Article
Times cited : (350)

References (65)
  • 3
    • 84880309916 scopus 로고    scopus 로고
    • Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
    • Scheel TK, Rice CM, (2013) Understanding the hepatitis C virus life cycle paves the way for highly effective therapies. Nature medicine 19: 837–849.
    • (2013) Nature medicine , vol.19 , pp. 837-849
    • Scheel, T.K.1    Rice, C.M.2
  • 5
    • 0042835565 scopus 로고    scopus 로고
    • To transplant or not to transplant recurrent hepatitis C and liver failure
    • Forman LM, (2003) To transplant or not to transplant recurrent hepatitis C and liver failure. Clinics in liver disease 7: 615–629.
    • (2003) Clinics in liver disease , vol.7 , pp. 615-629
    • Forman, L.M.1
  • 6
    • 38649100951 scopus 로고    scopus 로고
    • Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies
    • Timpe JM, Stamataki Z, Jennings A, Hu K, Farquhar MJ, et al. (2008) Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies. Hepatology 47: 17–24.
    • (2008) Hepatology , vol.47 , pp. 17-24
    • Timpe, J.M.1    Stamataki, Z.2    Jennings, A.3    Hu, K.4    Farquhar, M.J.5
  • 7
    • 84866152584 scopus 로고    scopus 로고
    • Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees
    • Morin TJ, Broering TJ, Leav BA, Blair BM, Rowley KJ, et al. (2012) Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees. PLoS pathogens 8: e1002895.
    • (2012) PLoS pathogens , vol.8 , pp. e1002895
    • Morin, T.J.1    Broering, T.J.2    Leav, B.A.3    Blair, B.M.4    Rowley, K.J.5
  • 8
    • 45749124737 scopus 로고    scopus 로고
    • Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems
    • Gottwein JM, Bukh J, (2008) Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems. Advances in virus research 71: 51–133.
    • (2008) Advances in virus research , vol.71 , pp. 51-133
    • Gottwein, J.M.1    Bukh, J.2
  • 9
    • 79951669627 scopus 로고    scopus 로고
    • Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies
    • Zeisel MB, Fofana I, Fafi-Kremer S, Baumert TF, (2011) Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. Journal of hepatology 54: 566–576.
    • (2011) Journal of hepatology , vol.54 , pp. 566-576
    • Zeisel, M.B.1    Fofana, I.2    Fafi-Kremer, S.3    Baumert, T.F.4
  • 10
    • 18644378971 scopus 로고    scopus 로고
    • The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus
    • Scarselli E, Ansuini H, Cerino R, Roccasecca RM, Acali S, et al. (2002) The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. The EMBO journal 21: 5017–5025.
    • (2002) The EMBO journal , vol.21 , pp. 5017-5025
    • Scarselli, E.1    Ansuini, H.2    Cerino, R.3    Roccasecca, R.M.4    Acali, S.5
  • 14
    • 77954040514 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes
    • Mancini N, Diotti RA, Perotti M, Sautto G, Clementi N, et al. (2009) Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes. PloS one 4: e8254.
    • (2009) PloS one , vol.4 , pp. e8254
    • Mancini, N.1    Diotti, R.A.2    Perotti, M.3    Sautto, G.4    Clementi, N.5
  • 17
    • 84867118648 scopus 로고    scopus 로고
    • Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy
    • Lee Y, El Andaloussi S, Wood MJ, (2012) Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy. Human molecular genetics 21: R125–134.
    • (2012) Human molecular genetics , vol.21 , pp. R125-134
    • Lee, Y.1    El Andaloussi, S.2    Wood, M.J.3
  • 20
    • 80053175966 scopus 로고    scopus 로고
    • Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
    • Yang M, Chen J, Su F, Yu B, Su F, et al. (2011) Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Molecular cancer 10: 117.
    • (2011) Molecular cancer , vol.10 , pp. 117
    • Yang, M.1    Chen, J.2    Su, F.3    Yu, B.4    Su, F.5
  • 21
    • 0036196022 scopus 로고    scopus 로고
    • Persistent and transient replication of full-length hepatitis C virus genomes in cell culture
    • Pietschmann T, Lohmann V, Kaul A, Krieger N, Rinck G, et al. (2002) Persistent and transient replication of full-length hepatitis C virus genomes in cell culture. Journal of virology 76: 4008–4021.
    • (2002) Journal of virology , vol.76 , pp. 4008-4021
    • Pietschmann, T.1    Lohmann, V.2    Kaul, A.3    Krieger, N.4    Rinck, G.5
  • 22
    • 77957933124 scopus 로고    scopus 로고
    • Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture
    • Gastaminza P, Dryden KA, Boyd B, Wood MR, Law M, et al. (2010) Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture. Journal of virology 84: 10999–11009.
    • (2010) Journal of virology , vol.84 , pp. 10999-11009
    • Gastaminza, P.1    Dryden, K.A.2    Boyd, B.3    Wood, M.R.4    Law, M.5
  • 24
    • 84867653559 scopus 로고    scopus 로고
    • Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity
    • Dreux M, Garaigorta U, Boyd B, Decembre E, Chung J, et al. (2012) Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity. Cell Host Microbe 12: 558–570.
    • (2012) Cell Host Microbe , vol.12 , pp. 558-570
    • Dreux, M.1    Garaigorta, U.2    Boyd, B.3    Decembre, E.4    Chung, J.5
  • 25
    • 22544470874 scopus 로고    scopus 로고
    • Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
    • Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, et al. (2005) Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nature medicine 11: 791–796.
    • (2005) Nature medicine , vol.11 , pp. 791-796
    • Wakita, T.1    Pietschmann, T.2    Kato, T.3    Date, T.4    Miyamoto, M.5
  • 26
    • 79551704610 scopus 로고    scopus 로고
    • Human Ago2 is required for efficient microRNA 122 regulation of hepatitis C virus RNA accumulation and translation
    • Wilson JA, Zhang C, Huys A, Richardson CD, (2011) Human Ago2 is required for efficient microRNA 122 regulation of hepatitis C virus RNA accumulation and translation. Journal of virology 85: 2342–2350.
    • (2011) Journal of virology , vol.85 , pp. 2342-2350
    • Wilson, J.A.1    Zhang, C.2    Huys, A.3    Richardson, C.D.4
  • 28
    • 46749124698 scopus 로고    scopus 로고
    • Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome
    • Jopling CL, Schutz S, Sarnow P, (2008) Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome. Cell host & microbe 4: 77–85.
    • (2008) Cell host & microbe , vol.4 , pp. 77-85
    • Jopling, C.L.1    Schutz, S.2    Sarnow, P.3
  • 29
    • 24644483623 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P, (2005) Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309: 1577–1581.
    • (2005) Science , vol.309 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 30
    • 77953315225 scopus 로고    scopus 로고
    • Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122
    • Jangra RK, Yi M, Lemon SM, (2010) Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122. Journal of virology 84: 6615–6625.
    • (2010) Journal of virology , vol.84 , pp. 6615-6625
    • Jangra, R.K.1    Yi, M.2    Lemon, S.M.3
  • 31
    • 84872148409 scopus 로고    scopus 로고
    • Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells
    • Bukong TN, Hou W, Kodys K, Szabo G, (2013) Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells. Hepatology 57: 70–80.
    • (2013) Hepatology , vol.57 , pp. 70-80
    • Bukong, T.N.1    Hou, W.2    Kodys, K.3    Szabo, G.4
  • 33
    • 84856032592 scopus 로고    scopus 로고
    • New insights into HCV replication: potential antiviral targets
    • Rice CM, (2011) New insights into HCV replication: potential antiviral targets. Topics in antiviral medicine 19: 117–120.
    • (2011) Topics in antiviral medicine , vol.19 , pp. 117-120
    • Rice, C.M.1
  • 34
    • 70450162452 scopus 로고    scopus 로고
    • Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus
    • Broering TJ, Garrity KA, Boatright NK, Sloan SE, Sandor F, et al. (2009) Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus. Journal of virology 83: 12473–12482.
    • (2009) Journal of virology , vol.83 , pp. 12473-12482
    • Broering, T.J.1    Garrity, K.A.2    Boatright, N.K.3    Sloan, S.E.4    Sandor, F.5
  • 35
    • 34248370961 scopus 로고    scopus 로고
    • CD81 expression is important for the permissiveness of Huh7 cell clones for heterogeneous hepatitis C virus infection
    • Akazawa D, Date T, Morikawa K, Murayama A, Miyamoto M, et al. (2007) CD81 expression is important for the permissiveness of Huh7 cell clones for heterogeneous hepatitis C virus infection. Journal of virology 81: 5036–5045.
    • (2007) Journal of virology , vol.81 , pp. 5036-5045
    • Akazawa, D.1    Date, T.2    Morikawa, K.3    Murayama, A.4    Miyamoto, M.5
  • 36
    • 0037416146 scopus 로고    scopus 로고
    • Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
    • Bartosch B, Dubuisson J, Cosset FL, (2003) Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes. The Journal of experimental medicine 197: 633–642.
    • (2003) The Journal of experimental medicine , vol.197 , pp. 633-642
    • Bartosch, B.1    Dubuisson, J.2    Cosset, F.L.3
  • 37
    • 84872148409 scopus 로고    scopus 로고
    • Ethanol facilitates HCV replication via upregulation of GW182 and HSP90 in human hepatoma cells
    • Bukong TN, Hou W, Kodys K, Szabo G, (2012) Ethanol facilitates HCV replication via upregulation of GW182 and HSP90 in human hepatoma cells. Hepatology 10.1002/hep.26010.
    • (2012) Hepatology
    • Bukong, T.N.1    Hou, W.2    Kodys, K.3    Szabo, G.4
  • 40
    • 65449118855 scopus 로고    scopus 로고
    • Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3
    • Ujino S, Yamaguchi S, Shimotohno K, Takaku H, (2009) Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3. J Biol Chem 284: 6841–6846.
    • (2009) J Biol Chem , vol.284 , pp. 6841-6846
    • Ujino, S.1    Yamaguchi, S.2    Shimotohno, K.3    Takaku, H.4
  • 41
  • 42
    • 33751223214 scopus 로고    scopus 로고
    • Hepatitis C virus entry requires a critical postinternalization step and delivery to early endosomes via clathrin-coated vesicles
    • Meertens L, Bertaux C, Dragic T, (2006) Hepatitis C virus entry requires a critical postinternalization step and delivery to early endosomes via clathrin-coated vesicles. Journal of virology 80: 11571–11578.
    • (2006) Journal of virology , vol.80 , pp. 11571-11578
    • Meertens, L.1    Bertaux, C.2    Dragic, T.3
  • 44
    • 67949097489 scopus 로고    scopus 로고
    • Exosomes–vesicular carriers for intercellular communication
    • Simons M, Raposo G, (2009) Exosomes–vesicular carriers for intercellular communication. Current opinion in cell biology 21: 575–581.
    • (2009) Current opinion in cell biology , vol.21 , pp. 575-581
    • Simons, M.1    Raposo, G.2
  • 46
    • 78650265541 scopus 로고    scopus 로고
    • Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes
    • Silverman JM, Reiner NE, (2011) Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes. Cellular microbiology 13: 1–9.
    • (2011) Cellular microbiology , vol.13 , pp. 1-9
    • Silverman, J.M.1    Reiner, N.E.2
  • 47
    • 36148959342 scopus 로고    scopus 로고
    • Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo
    • Bhatnagar S, Shinagawa K, Castellino FJ, Schorey JS, (2007) Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo. Blood 110: 3234–3244.
    • (2007) Blood , vol.110 , pp. 3234-3244
    • Bhatnagar, S.1    Shinagawa, K.2    Castellino, F.J.3    Schorey, J.S.4
  • 49
    • 0036893332 scopus 로고    scopus 로고
    • Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication
    • Blight KJ, McKeating JA, Rice CM, (2002) Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. Journal of virology 76: 13001–13014.
    • (2002) Journal of virology , vol.76 , pp. 13001-13014
    • Blight, K.J.1    McKeating, J.A.2    Rice, C.M.3
  • 50
    • 84871967004 scopus 로고    scopus 로고
    • Inhibition of alpha interferon (IFN-alpha)-induced microRNA-122 negatively affects the anti-hepatitis B virus efficiency of IFN-alpha
    • Hao J, Jin W, Li X, Wang S, Zhang X, et al. (2013) Inhibition of alpha interferon (IFN-alpha)-induced microRNA-122 negatively affects the anti-hepatitis B virus efficiency of IFN-alpha. J Virol 87: 137–147.
    • (2013) J Virol , vol.87 , pp. 137-147
    • Hao, J.1    Jin, W.2    Li, X.3    Wang, S.4    Zhang, X.5
  • 51
    • 58149333128 scopus 로고    scopus 로고
    • Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy
    • Sarasin-Filipowicz M, Krol J, Markiewicz I, Heim MH, Filipowicz W, (2009) Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nature medicine 15: 31–33.
    • (2009) Nature medicine , vol.15 , pp. 31-33
    • Sarasin-Filipowicz, M.1    Krol, J.2    Markiewicz, I.3    Heim, M.H.4    Filipowicz, W.5
  • 52
    • 77951712353 scopus 로고    scopus 로고
    • HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells
    • Johnston M, Geoffroy MC, Sobala A, Hay R, Hutvagner G, (2010) HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells. Molecular biology of the cell 21: 1462–1469.
    • (2010) Molecular biology of the cell , vol.21 , pp. 1462-1469
    • Johnston, M.1    Geoffroy, M.C.2    Sobala, A.3    Hay, R.4    Hutvagner, G.5
  • 54
    • 65449118855 scopus 로고    scopus 로고
    • Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3
    • Ujino S, Yamaguchi S, Shimotohno K, Takaku H, (2009) Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3. J Biol Chem 284: 6841–6846.
    • (2009) J Biol Chem , vol.284 , pp. 6841-6846
    • Ujino, S.1    Yamaguchi, S.2    Shimotohno, K.3    Takaku, H.4
  • 56
    • 0033767690 scopus 로고    scopus 로고
    • Exosome: from internal vesicle of the multivesicular body to intercellular signaling device
    • Denzer K, Kleijmeer MJ, Heijnen HF, Stoorvogel W, Geuze HJ, (2000) Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. Journal of cell science 113 Pt 19: 3365–3374.
    • (2000) Journal of cell science , vol.113 Pt 19 , pp. 3365-3374
    • Denzer, K.1    Kleijmeer, M.J.2    Heijnen, H.F.3    Stoorvogel, W.4    Geuze, H.J.5
  • 57
    • 70350374082 scopus 로고    scopus 로고
    • Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins
    • Sobota JA, Back N, Eipper BA, Mains RE, (2009) Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins. Journal of cell science 122: 3542–3553.
    • (2009) Journal of cell science , vol.122 , pp. 3542-3553
    • Sobota, J.A.1    Back, N.2    Eipper, B.A.3    Mains, R.E.4
  • 59
    • 34547093203 scopus 로고    scopus 로고
    • Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies
    • Vingtdeux V, Hamdane M, Loyens A, Gele P, Drobeck H, et al. (2007) Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies. The Journal of biological chemistry 282: 18197–18205.
    • (2007) The Journal of biological chemistry , vol.282 , pp. 18197-18205
    • Vingtdeux, V.1    Hamdane, M.2    Loyens, A.3    Gele, P.4    Drobeck, H.5
  • 61
    • 33751072389 scopus 로고    scopus 로고
    • Bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1alpha
    • Lim JH, Park JW, Kim MS, Park SK, Johnson RS, et al. (2006) Bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1alpha. Molecular pharmacology 70: 1856–1865.
    • (2006) Molecular pharmacology , vol.70 , pp. 1856-1865
    • Lim, J.H.1    Park, J.W.2    Kim, M.S.3    Park, S.K.4    Johnson, R.S.5
  • 63
    • 84868211262 scopus 로고    scopus 로고
    • Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases
    • Bala S, Petrasek J, Mundkur S, Catalano D, Levin I, et al. (2012) Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology 56: 1946–1957.
    • (2012) Hepatology , vol.56 , pp. 1946-1957
    • Bala, S.1    Petrasek, J.2    Mundkur, S.3    Catalano, D.4    Levin, I.5
  • 64
    • 0029972796 scopus 로고    scopus 로고
    • Cultivation of hepatitis C virus in primary hepatocyte culture from patients with chronic hepatitis C results in release of high titre infectious virus
    • Ito T, Mukaigawa J, Zuo J, Hirabayashi Y, Mitamura K, et al. (1996) Cultivation of hepatitis C virus in primary hepatocyte culture from patients with chronic hepatitis C results in release of high titre infectious virus. The Journal of general virology 77 (Pt 5) 1043–1054.
    • (1996) The Journal of general virology , vol.77 , pp. 1043-1054
    • Ito, T.1    Mukaigawa, J.2    Zuo, J.3    Hirabayashi, Y.4    Mitamura, K.5
  • 65
    • 84887022985 scopus 로고    scopus 로고
    • Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection
    • Bukong TN, Kodys K, Szabo G, (2013) Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection. Hepatology 58: 1569–1579.
    • (2013) Hepatology , vol.58 , pp. 1569-1579
    • Bukong, T.N.1    Kodys, K.2    Szabo, G.3


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