Lack of Galectin-3 Prevents Cardiac Fibrosis and Effective Immune Responses in a Murine Model of Trypanosoma cruzi Infection

Journal of Infectious Diseases

Volumn 212, Issue 7, 2015, Pages 1160-1171

  Pineda, Miguel A ^a,b   Cuervo, Henar ^a,c   Fresno, Manuel ^a   Soto, Manuel ^a   Bonay, Pedro ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c Department of Medicine   (United States)

Author keywords

cardiac fibrosis; galectin 3; inflammation; innate immunity; Toll like receptor; Trypanosoma cruzi

Indexed keywords

COLLAGEN; GALECTIN 3; TOLL LIKE RECEPTOR; BETA-GALACTOSIDE; CELL SURFACE RECEPTOR; GALACTOSIDE; SACCHARIDE-BINDING PROTEINS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CELL CULTURE; CELL INFILTRATION; CHAGAS DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HEART MUSCLE FIBROSIS; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; TISSUE INJURY; TRYPANOSOMA CRUZI; ANIMAL; CHAGAS CARDIOMYOPATHY; CHLOROCEBUS AETHIOPS; FIBROSIS; HEART MUSCLE; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PARASITEMIA; PARASITOLOGY; PATHOLOGY; VERO CELL LINE;

ANIMALS; ANTIGEN-PRESENTING CELLS; CERCOPITHECUS AETHIOPS; CHAGAS CARDIOMYOPATHY; CHAGAS DISEASE; FIBROSIS; GALACTOSIDES; GALECTIN 3; HUMANS; IMMUNITY, INNATE; MICE; MICE, KNOCKOUT; MYOCARDIUM; PARASITEMIA; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTORS; TRYPANOSOMA CRUZI; VERO CELLS;

EID: 84943419905     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv185     Document Type: Article

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