Proteolytic generation of kinins in tissues infected by Trypanosoma cruzi depends on CXC chemokine secretion by macrophages activated via Toll-like 2 receptors

Journal of Leukocyte Biology

Volumn 85, Issue 6, 2009, Pages 1005-1014

  Schmitz, Veronica ^a   Svensjö, Erik ^a   Serra, Rafaela Rangel ^a   Teixeira, Mauro M ^b   Scharfstein, Julio ^a,c  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c Edifício do Centro de Ciências da Saúde ^*  (Brazil)

Author keywords

Bradykinin; Cruzipain; CXCR2; TLR2

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CXCR2; ICATIBANT; KININ; REPERTAXIN; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG; BRADYKININ B2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; EDEMA; EPIMASTIGOTE; HAMSTER; IN VITRO STUDY; INNATE IMMUNITY; KERATINOCYTE; LEUKOCYTE; MACROPHAGE ACTIVATION; MALE; MICROSCOPY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRYPOMASTIGOTE; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INFLAMMATION; LIFE CYCLE; MACROPHAGE; METABOLISM; PARASITE; PARASITOLOGY; PHENOTYPE; PHYSIOLOGY; PROTEIN PROCESSING; SECRETION; SIGNAL TRANSDUCTION; TRYPANOSOMA CRUZI;

CRICETINAE; HEXAPODA; MUS; PROTOZOA; TRYPANOSOMA CRUZI;

ANIMALS; CHEMOKINES, CXC; CRICETINAE; EDEMA; GENOTYPE; INFLAMMATION; KININS; LIFE CYCLE STAGES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MODELS, IMMUNOLOGICAL; ORGAN SPECIFICITY; PARASITES; PHENOTYPE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, BRADYKININ B2; RECEPTORS, INTERLEUKIN-8B; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TRYPANOSOMA CRUZI;

EID: 67149135208     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1108693     Document Type: Article

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