Parasite persistence correlates with disease severity and localization in chronic Chagas' disease

Journal of Infectious Diseases

Volumn 180, Issue 2, 1999, Pages 480-486

  Zhang, L ^a,b   Tarleton, Rick L ^a,b  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KINETOPLAST DNA; PARASITE ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CHAGAS DISEASE; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE SEVERITY; ENDEMIC DISEASE; FEMALE; HEART DISEASE; HEART TRANSPLANTATION; MALE; MOUSE; MUSCLE TISSUE; NONHUMAN; PERSISTENT INFECTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SYMPTOM; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS CARDIOMYOPATHY; CHAGAS DISEASE; CHRONIC DISEASE; DNA, KINETOPLAST; FEMALE; HEART; HEART TRANSPLANTATION; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MUSCLE, SKELETAL; MYOCARDIUM; POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; TRYPANOSOMA CRUZI;

EID: 0033495303     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314889     Document Type: Article

References (42)

1. 1. Koberle F. Chagas' disease and Chagas' syndromes: the pathology of American trypanosomiasis. Adv Parasitol 1968;6:63-116.
2. 2. Takle GB, Hudson L. Autoimmunity and Chagas' disease. Curr Top Microbiol Immunol 1989;145:79-92.
3. 3. Kalil J, Cunha-Neto E. Autoimmunity in Chagas' disease cardiomyopathy: fulfilling the criteria at last? Parasitol Today 1996;12:396-9.
4. 4. Jones EM, Colley DG, Tostes S, Lopes ER, Vnencak JC, McCurley TL. Amplification of a Trypanosoma cruzi DNA sequence from inflammatory lesions in human chagasic cardiomyopathy. Am J Trop Med Hyg 1993; 48:348-57.
5. 5. Miguchi MDL, Brito TD, Reis MM, et al. Correlation between Trypanosoma cruzi parasitism and myocardial inflammatory infiltrate in human chronic chagasic myocarditis: light microscopy and immunohistochemical findings. Cardiovasc Pathol 1993;2:101-6.
6. 6. Bellotti G, Bocchi EA, de Moraes AV, et al. In vivo detection of Trypanosoma cruzi antigens in hearts of patients with chronic Chagas' heart disease. Am Heart J 1996;131:301-7.
7. 7. Reis MM, Higuchi MDL, Benvenuti LA, et al. An in situ quantitative immunohistochcmical study of cytokines and IL-2R + in chronic human chagasic myocarditis: correlation with the presence of myocardial Trypanosoma cruzi antigens. Clin Immunol Immunopathol 1997;83:165-72.
8. 8. Brandariz S, Schijman A, Vigliano C, et al. Detection of parasite DNA in Chagas' heart disease. Lancet 1995;346:1370-1.
9. 9. Vago AR, Macedo AM, Oliveira RP, et al. Kinetoplast DNA signatures of Trypanosoma cruzi strains obtained directly from infected tissues. Am J Pathol 1996;149:2153-9.
10. 10. Vago AR, Macedo AM, Adad SJ, Reis DD, Correa-Oliveira R. PCR detection of Trypanosoma cruzi DNA in oesophageal tissues of patients with chronic digestive Chagas' disease. Lancet 1996;348:891-2.
11. 11. Ben Younes-Chennoufi A, Hontebeyrie-Joskowicz M, Tricottet V, Eisen H, Reynes M, Said G. Persistence of Trypanosomn cruzi antigens in the inflammatory lesions of chronically infected mice. Trans R Soc Trop Med Hyg 1988;82:77-83.
12. 12. Lane JE, Olivares-Villagomez D, Vneneak-Joncs CL, McCurley TL, Carter CE. Detection of Trypanosoma cruzi with the polymerase chain reaction and in situ hybridization in infected murine cardiac tissue. Am J Trop Med Hyg 1997;56:588-95.
13. 13. Tarleton RL, Zhang L, Downs MO. "Autoimmune rejection" of neonatal heart transplants in experimental Chagas' disease is a parasite-specific response to infected host tissue. Proc Natl Acad Sci USA 1997;94:3932-7.
14. 14. Viotti R, Vigliano C, Armenti H, Segura E. Treatment of chronic Chagas' disease with benznidazole: clinical and serologic evolution of patients with long-term follow-up. Am Heart J 1994;127:151-62.
15. 15. Postan M, Dvorak JA, McDaniel JA. Studies of Trypanosoma cruzi clones in inbred mice. I. A comparison of the course of infection of C3H/HEN-mice with two clones isolated from a common source. Am J Trop Med Hyg 1983;32:497-506.
16. + T lymphocytes in the inflammatory lesions of mice with acute Trypanosoma cruzi infection. Am J Trop Med Hyg 1993;45:161-9.
17. 17. Simpson L, Berliner J. Isolation of the kinetoplast DNA of Leishmania tarentolae in the form of a network. J Protozool 1974;21:382-93.
18. 18. Monteon VM, Furuzawa-Carballeda J, Alejandre-Aguilar R, Aranda-Fraustro A, Rosales-Encina JL, Reyes PA, American trypanosomosis: in situ and generalized features of parasitism find inflammation kinetics in a murine model. Exp Parasitol 1996;83:267-74.
19. 19. Santos-Buch CA, Acosta AM. Pathology of Chagas' disease. In: Tizard I, ed. Immunology and pathogenesis of trypanosomiasis. Boca Raton, FL: CRC Press, 1985:145-83.
20. 20. Koherle F. Pathogenesis of Chagas' disease: trypanosomiasis and leishmaniasis with special reference to Chagas disease: Ciba Found Symp 20. Amsterdam: Elsevier, 1974:137-58.
21. 21. Rossi MA. Microvascular changes as a cause of chronic cardiomyopathy in Chagas' disease. Am Heart J 1990;120:233-6.
22. 22. Cunha-Neto E, Duranti M, Gruber A, et al. Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope cross-reactive to an immunodominant Trypanosoma cruzi antigen. Proc Natl Acad Sci USA 1995;92:3541-5.
23. 23. Cunha-Neto E, Coelho V, Guilherme L, Fiorelli A, Stolf N, Kalil J. Autoimmunity in Chagas' disease: identification of cardiac myosin-B13 Trypanosoma cruzi protein cross-veactive T cell clones in heart lesions of a chronic Chagas' cardiomyopathy patient. J Clin Invest 1996;98;1709-12.
24. 24. Mosca W, Plaja J. Delayed hypersensitivity to heart antigens in Chagas' disease as measured by in vitro lymphocyte stimulation. J Clin Microbiol 1981;14:15.
25. 25. Cossio PM, Laguens RP, Diez C, Szarfman A, Segal A, Arana RM, Chagasic cardiopathy: antibodies reading with plasma membrane of striated muscle and endothelial cells. Circulation 1974;50:1252-9.
26. 26. Teixeira ARL, Teixeira G, Macedo V, Prata A. Trypanosoma cruzi sensitized T lymphocyte-mediated 51-CR release from human heart cells in Chagas' disease. Am J Trop Med Hyg 1978;27:1097-107.
27. 27. Ribeiro dos Santos R, Rossi MA, Laus JL, Silva JS, Savino W, Mengel J. Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruzi. J Esp Med 1992;175:29-39.
28. 28. Postan M, McDaniel JP, Dvorak JA. Studies of Trypanosoma cruzi clones in inbred mice. II. Course of infection of C57BL/6 mice with single cell-isolates stocks. Am J Trop Med Hyg 1984;33:236-8.
29. 29. Postan M, Cheever AW, Dvorak JA, McDaniel JP. A histopathological analysis of the course of myocarditis in C3H/HeN mice infected with Trypanosoma cruzi clone Sylvio-X10/4. Trans R Soc Trop Med Hyg 1986; 80:50-5.
30. + Tcl responses. J Immunol 1997;159:6120-30.
31. 31. Tarleton RL, Koller BH, Latour A, Postan M. Susceptibility of β32-microglobulin -deficient mice to Trypanosoma cruzi infection. Nature 1992;356: 338-40.
32. 32. Tarleton RL, Grusby MJ, Postan MJ, Glimcher LH. Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I and class II restricted T cells in immune resistance and disease. Int Immunol 1996;8:13-22.
33. 33. Olivares-Villagomez D, McCurley TL, Vnencak-Jones CL, Correa-Oliveira R, Colley DG, Carter CE. Polymerase chain reaction amplification of three different Trypanosoma cruzi DNA sequences from human chagasic cardiac tissue. Am J Trop Med Hyg 1998;59:563-70.
34. 34. Almeida DR, Carvalho AC, Branco JN, et al. Chagas' disease reactivation after heart transplantation: efficacy of allopurinol treatment. J Heart Lung Transplant 1996;15:988-92.
35. 35. Jardim E, Takayanagui OM. Chagasic meningoencephalitis with detection of Trypanosoma cruzi in the cerebrospinal fluid of an immunodepressed patient. J Trop Med Hyg 1994;97:367-70.
36. 36. Sartori A, Lopes MH, Caramelli B, et al. Simultaneous occurrence of acute myocarditis and reactivated Chagas' disease in a patient with AIDS. Clin Infect Dis 1995;21:1297-9.
37. 37. Silva JS, Rossi MA. Intensification of acute Trypanosoma cruzi myocarditis in BALB/c mice pretreated with low doses of cyclophosphamide or gamma irradiation. J Exp Pathol 1990;71:33-9.
38. 38. Andrade ZA, Andrade SG, Sadigursky M. Enhancement of chronic Trypanosoma cruzi myocarditits in dogs treated with low doses of cyclophosphamide. Am J Pathol 1987;127:467-73.
39. 39. Tarleton RL, Sun J, Zhang L, Postan M. Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease. Infect Immun 1994;62:1820-9.
40. 40. Postan M, Correa R, Ferrans VJ, Tarleton RL. In vitro culture of cardiac mast cells from mice experimentally infected with Trypanosama cruzi. Int Arch Allergy Immunol 1994;105:251-7.
41. 41. Higuchi ML, De Morais CF, Pereira Barreto AC, et al. The role of active myocarditis in the development of heart failure in chronic Chagas' disease: a study based on endomyocardial biopsies. Clin Cardiol 1987;10:665-70.
42. + T cells wilh the presence of Trypanosoma cruzi antigens in chronic, human, chagasic myocarditis. Am J Trop Med Hyg 1997;56:485-9.