Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase i induction

Biochemical Pharmacology

Volumn 97, Issue 4, 2015, Pages 473-481

  Navarro, Elisa ^a,b   Buendia, Izaskun ^a,b   Parada, Esther ^a,b   León, Rafael ^a,c   Jansen Duerr, Pidder ^d   Pircher, Haymo ^d   Egea, Javier ^a,c   Lopez, Manuela G ^a,b,c  

^a INSTITUTO TEÓFILO HERNANDO   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c Instituto de Investigación Sanitaria del Hospital Universitario de La Princesa   (Spain)

^d UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Heme oxygenase I; Neuroprotection; Organotypic cultures; Oxidative stress; Protein aggregation; 7 nicotinic receptor

Indexed keywords

ANTIMYCIN A1; BUNGAROTOXIN RECEPTOR; HEME OXYGENASE 1; LIPOPOLYSACCHARIDE; PROPIDIUM IODIDE; PROTOPORPHYRIN TIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; UBIQUINOL CYTOCHROME C REDUCTASE; BENZAMIDE DERIVATIVE; BICYCLO COMPOUND; HEME OXYGENASE; HMOX1 PROTEIN, RAT; NICOTINIC AGENT; PNU-282987;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEPOLARIZATION; ENZYME INDUCTION; FLUORESCENCE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; IN VITRO STUDY; MITOCHONDRION; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; RAT; AGONISTS; ANIMAL; CELL CULTURE; CELL DEATH; CYTOLOGY; DRUG EFFECTS; GENETICS; HIPPOCAMPUS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; ANTIMYCIN A; BENZAMIDES; BICYCLO COMPOUNDS; CELL DEATH; CELLS, CULTURED; ENZYME INDUCTION; HEME OXYGENASE (DECYCLIZING); HIPPOCAMPUS; LIPOPOLYSACCHARIDES; MITOCHONDRIA; NICOTINIC AGONISTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 84943365537     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.07.022     Document Type: Article

References (40)

1. L. Gimenez-Llort, I. Mate, R. Manassra, C. Vida, and M. De la Fuente Peripheral immune system and neuroimmune communication impairment in a mouse model of Alzheimer's disease Ann. N. Y. Acad. Sci. 1262 July 2012 74 84
2. K. Dasuri, L. Zhang, and J.N. Keller Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis Free Radic. Biol. Med. 62 September 2013 170 185
3. X. Zhu, B. Su, X. Wang, M.A. Smith, and G. Perry Causes of oxidative stress in Alzheimer disease Cell Mol. Life Sci. 64 September (17) 2007 2202 2210
4. W.R. Markesbery Oxidative stress hypothesis in Alzheimer's disease Free Radic. Biol. Med. 23 1 1997 134 147
5. M.E. Witte, J.J.G. Geurts, H.E. de Vries, P. van der Valk, and J. van Horssen Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? Mitochondrion 10 5 2010 411 418 10.1016/j.mito.2010.05.014
6. J. Emerit, M. Edeas, and F. Bricaire Neurodegenerative diseases and oxidative stress Biomed. Pharmacother. 58 January (1) 2004 39 46
7. P.J. Vernon, and D. Tang Eat-me: autophagy, phagocytosis, and reactive oxygen species signaling Antioxid. Redox Signal. 18 Feburary (6) 2013 677 691
8. S. Tzikas, D. Schlak, K. Sopova, K. Gatsiou, D. Stakos, K. Stamatelopoulos, and et al. Increased myeloperoxidase plasma levels in patients with Alzheimer's disease J. Alzheimers Dis. November 2013
9. G.E. Gibson, K.F. Sheu, and J.P. Blass Abnormalities of mitochondrial enzymes in Alzheimer disease J. Neural Transm. 105 8-9 1998 855 870
10. P.I. Moreira, X. Zhu, X. Wang, H.G. Lee, A. Nunomura, R.B. Petersen, and et al. Mitochondria: a therapeutic target in neurodegeneration Biochim. Biophys. Acta 1802 January (1) 2010 212 220
11. M.T. Lin, and M.F. Beal Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 October (7113) 2006 787 795
12. M. Bencherif Neuronal nicotinic receptors as novel targets for inflammation and neuroprotection: mechanistic considerations and clinical relevance Acta Pharmacol. Sin. 30 June (6) 2009 702 714
13. J. Kawamata, and S. Shimohama Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases J. Alzheimers Dis. 24 Suppl. 2 2011 95 109
14. L.V. Borovikova, S. Ivanova, M. Zhang, H. Yang, G.I. Botchkina, L.R. Watkins, and et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Nature 405 May (6785) 2000 458 462
15. H. Wang, M. Yu, M. Ochani, C.A. Amella, M. Tanovic, S. Susarla, and et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation Nature 421 January (6921) 2003 384 388
16. E. Parada, J. Egea, I. Buendia, P. Negredo, A.C. Cunha, S. Cardoso, and et al. The microglial alpha7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2 Antioxid. Redox Signal. Feburary 2013
17. E. Parada, J. Egea, A. Romero, L. del Barrio, A.G. Garcia, and M.G. Lopez Poststress treatment with PNU282987 can rescue SH-SY5Y cells undergoing apoptosis via alpha7 nicotinic receptors linked to a Jak2/Akt/HO-1 signaling pathway Free Radic. Biol Med. 49 December (11) 2010 1815 1821
18. L. Stoppini, P.A. Buchs, and D. Muller A simple method for organotypic cultures of nervous tissue J. Neurosci. Methods 37 April (2) 1991 173 182
19. M.F. Beal Mitochondria take center stage in aging and neurodegeneration Ann. Neurol. 58 October (4) 2005 495 505
20. A. Ngkelo, K. Meja, M. Yeadon, I. Adcock, and P.A. Kirkham LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gialpha dependent PI-3kinase signalling J. Inflamm. (Lond.) 9 1 2012 1
21. H.S. Park, H.Y. Jung, E.Y. Park, J. Kim, W.J. Lee, and Y.S. Bae Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B J. Immunol. 173 September (6) 2004 3589 3593
22. I. Buendia, J. Egea, E. Parada, E. Navarro, R. Leon, M.I. Rodriguez-Franco, and et al. The melatonin-N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction ACS Chem. Neurosci. 6 Feburary (2) 2015 288 296
23. D. Harman Aging: a theory based on free radical and radiation chemistry J. Gerontol. 11 July (3) 1956 298 300
24. C. Franceschi, M. Bonafe, S. Valensin, F. Olivieri, M. De Luca, E. Ottaviani, and et al. Inflamm-aging. An evolutionary perspective on immunosenescence Ann. N. Y. Acad. Sci. 908 June 2000 244 254
25. M. De la Fuente, and J. Miquel An update of the oxidation-inflammation theory of aging: the involvement of the immune system in oxi-inflamm-aging Curr. Pharm. Des. 15 26 2009 3003 3026
26. D. Pratico Oxidative stress hypothesis in Alzheimer's disease: a reappraisal Trends Pharmacol. Sci. 29 December (12) 2008 609 615
27. S.J. Park, H.J. Jung, M.S. Son, J.M. Jung, D.H. Kim, I.H. Jung, and et al. Neuroprotective effects of INM-176 against lipopolysaccharide-induced neuronal injury Pharmacol. Biochem. Behav. 101 May (3) 2012 427 433
28. A. di Penta, B. Moreno, S. Reix, B. Fernandez-Diez, M. Villanueva, O. Errea, and et al. Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation PLoS ONE 8 2 2013 e54722
29. C. Ullrich, and C. Humpel Rotenone induces cell death of cholinergic neurons in an organotypic co-culture brain slice model Neurochem. Res. 34 December (12) 2009 2147 2153
30. R.H. Hughes, V.A. Silva, I. Ahmed, D.I. Shreiber, and B. Morrison III Neuroprotection by genipin against reactive oxygen and reactive nitrogen species-mediated injury in organotypic hippocampal slice cultures Brain Res. 1543 January 2014 308 314
31. A.A. Miller, G.R. Drummond, and C.G. Sobey Novel isoforms of NADPH-oxidase in cerebral vascular control Pharmacol. Ther. 111 September (3) 2006 928 948
32. A.J. Bruce-Keller, S. Gupta, A.G. Knight, T.L. Beckett, J.M. McMullen, P.R. Davis, and et al. Cognitive impairment in humanized APPxPS1 mice is linked to Abeta(1-42) and NOX activation Neurobiol Dis. 44 December (3) 2011 317 326
33. W.M. Zawada, R.E. Mrak, J. Biedermann, Q.D. Palmer, S.M. Gentleman, O. Aboud, and et al. Loss of angiotensin II receptor expression in dopamine neurons in Parkinson's disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation Acta Neuropathol. Commun. 3 1 2015 9
34. M. Halliday, and G.R. Mallucci Targeting the unfolded protein response in neurodegeneration: a new approach to therapy Neuropharmacology 76 January (Pt A) 2014 169 174
35. X. Wang, T. Huang, G. Bu, and H. Xu Dysregulation of protein trafficking in neurodegeneration Mol. Neurodegener. 9 2014 31
36. J.L. Yakel Nicotinic ACh receptors in the hippocampal circuit; functional expression and role in synaptic plasticity J. Physiol. 592 October (Pt 19) 2014 4147 4153
37. Y. Liu, X. Zeng, Y. Hui, C. Zhu, J. Wu, D.H. Taylor, and et al. Activation of alpha7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: implications for Parkinson's disease Neuropharmacology 91 April 2015 87 96
38. H.J. Park, P.H. Lee, Y.W. Ahn, Y.J. Choi, G. Lee, D.Y. Lee, and et al. Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action Eur. J. Neurosci. 26 July (1) 2007 79 89
39. T. Kihara, S. Shimohama, H. Sawada, K. Honda, T. Nakamizo, H. Shibasaki, and et al. alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity J. Biol. Chem. 276 April (17) 2001 13541 13546
40. R. Medeiros, N.A. Castello, D. Cheng, M. Kitazawa, D. Baglietto-Vargas, K.N. Green, and et al. alpha7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles Am. J. Pathol. 184 Feburary (2) 2014 520 529