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Volumn 854, Issue , 2016, Pages 355-361

Can vitamin A be improved to prevent blindness due to age-related macular degeneration, stargardt disease and other retinal dystrophies?

Author keywords

A2E; ABCA4; Age related macular degeneration; ALK 001; AMD; Bisretinoids; C20 D3 vitamin A; Lipofuscin; Retinal dystrophies; Retinaldehyde; Stargardt; Visual cycle; Vitamin A; Vitamin A dimer

Indexed keywords

AGENTS ACTING ON THE EYE; BETA CAROTENE; DEUTERIUM VITAMIN A; LIPOFUSCIN; RETINOL; UNCLASSIFIED DRUG; DEUTERIUM; DIPHENYL ETHER DERIVATIVE; EMIXUSTAT; PROPANOLAMINE DERIVATIVE; VITAMIN;

EID: 84943339757     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-17121-0_47     Document Type: Chapter
Times cited : (16)

References (19)
  • 1
    • 12144288116 scopus 로고    scopus 로고
    • Safety and efficacy of dose-intensive oral vitamin A in subjects with sun-damaged skin
    • Alberts D, Ranger-Moore J, Einspahr J et al (2004) Safety and efficacy of dose-intensive oral vitamin A in subjects with sun-damaged skin. Clin Cancer Res 10:1875-1880
    • (2004) Clin Cancer Res , vol.10 , pp. 1875-1880
    • Alberts, D.1    Ranger-Moore, J.2    Einspahr, J.3
  • 2
    • 0036712437 scopus 로고    scopus 로고
    • Estimating the potential for vitamin A toxicity in women and young children
    • Allen LH, Haskell M (2002) Estimating the potential for vitamin A toxicity in women and young children. J Nutr 132:2907S-2919S
    • (2002) J Nutr , vol.132 , pp. 2907S-2919S
    • Allen, L.H.1    Haskell, M.2
  • 3
    • 84936797991 scopus 로고    scopus 로고
    • Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization
    • Charbel Issa P, Barnard A, Herrmann P et al (2015) Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization. Proc Natl Acad Sci doi: 10.1073/ pnas.1506960112
    • (2015) Proc Natl Acad Sci
    • Charbel Issa, P.1    Barnard, A.2    Herrmann, P.3
  • 4
    • 84930433977 scopus 로고    scopus 로고
    • Phase II, randomized, placebo-controlled, 90-day study of emixustat hydrochloride in geographic atrophy associated with dry age-related macular degeneration
    • Dugel PU, Novack RL, Csaky KG et al (2015) Phase II, randomized, placebo-controlled, 90-day study of emixustat hydrochloride in geographic atrophy associated with dry age-related macular degeneration. Retina 35:1173-83
    • (2015) Retina , vol.35 , pp. 1173-1183
    • Dugel, P.U.1    Novack, R.L.2    Csaky, K.G.3
  • 5
    • 44349161777 scopus 로고    scopus 로고
    • Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina
    • Golczak M, Maeda A, Bereta G et al (2008) Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. J Biol Chem 283:9543-9554
    • (2008) J Biol Chem , vol.283 , pp. 9543-9554
    • Golczak, M.1    Maeda, A.2    Bereta, G.3
  • 6
    • 0026031549 scopus 로고
    • Laboratory evaluation during high-dose vitamin A administration: A randomized study on lung cancer patients after surgical resection
    • Infante M, Pastorino U, Chiesa G et al (1991) Laboratory evaluation during high-dose vitamin A administration: a randomized study on lung cancer patients after surgical resection. J Cancer Res Clin Oncol 117:156-162
    • (1991) J Cancer Res Clin Oncol , vol.117 , pp. 156-162
    • Infante, M.1    Pastorino, U.2    Chiesa, G.3
  • 7
    • 84943324697 scopus 로고    scopus 로고
    • Kahun (~ 1825 B.C) Kahun Gynecological Papyrus
    • Kahun (~ 1825 B.C) Kahun Gynecological Papyrus
  • 8
    • 79953145921 scopus 로고    scopus 로고
    • Deuterium enrichment of vitamin A at the C20 position slows the formation of detrimental vitamin A dimers in wild-type rodents
    • Kaufman Y, Ma L, Washington I (2011) Deuterium enrichment of vitamin A at the C20 position slows the formation of detrimental vitamin A dimers in wild-type rodents. J Biol Chem 286:7958-7965
    • (2011) J Biol Chem , vol.286 , pp. 7958-7965
    • Kaufman, Y.1    Ma, L.2    Washington, I.3
  • 9
    • 79953140506 scopus 로고    scopus 로고
    • C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of stargardt disease
    • Ma L, Kaufman Y, Zhang J et al (2011) C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of stargardt disease. J Biol Chem 286:7966-7974
    • (2011) J Biol Chem , vol.286 , pp. 7966-7974
    • Ma, L.1    Kaufman, Y.2    Zhang, J.3
  • 10
    • 84856110195 scopus 로고    scopus 로고
    • Primary amines protect against retinal degeneration in mouse models of retinopathies
    • Maeda A, Golczak M, Chen Y et al (2012) Primary amines protect against retinal degeneration in mouse models of retinopathies. Nature Chem Biol 8:170-178
    • (2012) Nature Chem Biol , vol.8 , pp. 170-178
    • Maeda, A.1    Golczak, M.2    Chen, Y.3
  • 11
    • 31044444376 scopus 로고    scopus 로고
    • Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation
    • Maiti P, Kong J, Kim SR et al (2006) Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation. Biochemistry 45:852-860
    • (2006) Biochemistry , vol.45 , pp. 852-860
    • Maiti, P.1    Kong, J.2    Kim, S.R.3
  • 12
    • 84874950305 scopus 로고    scopus 로고
    • Investigation of oral fenretinide for treatment of geographic atrophy in age-related macular degeneration
    • Mata NL, Lichter JB, Vogel R et al (2013) Investigation of oral fenretinide for treatment of geographic atrophy in age-related macular degeneration. Retina 33:498-507
    • (2013) Retina , vol.33 , pp. 498-507
    • Mata, N.L.1    Lichter, J.B.2    Vogel, R.3
  • 13
    • 84880851196 scopus 로고    scopus 로고
    • The retina rapidly incorporates ingested C20-D(3)-vitamin A in a swine model
    • Mihai DM, Jiang H, Blaner WS et al (2013) The retina rapidly incorporates ingested C20-D(3)-vitamin A in a swine model. Mol Vis 19:1677-1683
    • (2013) Mol Vis , vol.19 , pp. 1677-1683
    • Mihai, D.M.1    Jiang, H.2    Blaner, W.S.3
  • 14
    • 0642368408 scopus 로고    scopus 로고
    • Water-miscible, emulsified, and solid forms of retinol supplements are more toxic than oil-based preparations
    • Myhre AM, Carlsen MH, Bohn SK et al (2003) Water-miscible, emulsified, and solid forms of retinol supplements are more toxic than oil-based preparations. Am J Clin Nutri 78:1152-1159
    • (2003) Am J Clin Nutri , vol.78 , pp. 1152-1159
    • Myhre, A.M.1    Carlsen, M.H.2    Bohn, S.K.3
  • 15
    • 0030325536 scopus 로고    scopus 로고
    • Clinical development plan: Vitamin A
    • NCI (1996) Clinical development plan: vitamin A. J Cell Biochem Suppl 26:269-307
    • (1996) J Cell Biochem Suppl , vol.26 , pp. 269-307
    • NCI1
  • 16
    • 0037447253 scopus 로고    scopus 로고
    • Treatment with isotretinion inhibits lipuscin accumulationin a mouse model of recessive stargardt macular degeneration
    • Radu RA, Mata NL, Nusinowitz S et al (2003) Treatment with isotretinion inhibits lipuscin accumulationin a mouse model of recessive stargardt macular degeneration. Proc Natl Acad Sci U S A 100:4742-4747
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4742-4747
    • Radu, R.A.1    Mata, N.L.2    Nusinowitz, S.3
  • 17
    • 33644795859 scopus 로고    scopus 로고
    • Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: A potential therapy for treatment of lipofuscin-based retinal diseases
    • Radu RA, Han Y, Bui TV et al (2005) Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases. Invest Ophthalmol Vis Sci 46:4393-4401
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4393-4401
    • Radu, R.A.1    Han, Y.2    Bui, T.V.3
  • 18
    • 0029837377 scopus 로고    scopus 로고
    • Plasma kinetics of vitamin A in humans after a single oral dose of [8, 9, 19-13C]retinyl palmitate
    • Reinersdorff DV, Bush E, Liberato DJ (1996) Plasma kinetics of vitamin A in humans after a single oral dose of [8, 9, 19-13C]retinyl palmitate. J Lipid Res 37:1875-1885
    • (1996) J Lipid Res , vol.37 , pp. 1875-1885
    • Reinersdorff, D.V.1    Bush, E.2    Liberato, D.J.3
  • 19
    • 33747418977 scopus 로고    scopus 로고
    • Amino-retinoid compounds in the human retinal pigment epithelium
    • Vollmer-Snarr HR, Pew MR, Alvarez ML et al (2006) Amino-retinoid compounds in the human retinal pigment epithelium. Adv Exp Med Biol 572:69-74
    • (2006) Adv Exp Med Biol , vol.572 , pp. 69-74
    • Vollmer-Snarr, H.R.1    Pew, M.R.2    Alvarez, M.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.