Deuterium enrichment of vitamin A at the C20 position slows the formation of detrimental vitamin A dimers in wild-type rodents

Journal of Biological Chemistry

Volumn 286, Issue 10, 2011, Pages 7958-7965

  Kaufman, Yardana ^a   Ma, Li ^a   Washington, Ilyas ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; BIOCHEMISTRY; BIOSYNTHESIS; DEUTERIUM; DIMERIZATION; MAMMALS;

AGE-RELATED MACULAR DEGENERATION; GRANULAR DEPOSITS; INTRINSIC REACTIVITY; MACULAR DEGENERATION; NATURAL ABUNDANCE; RETINAL PIGMENT EPITHELIUM; STARGARDT DISEASE; THERAPEUTIC INTERVENTION;

OPHTHALMOLOGY;

3,7,11 TRIMETHYLDODECA 2,6,10 TRIENOIC ACID HEXADECYLAMIDE; AMIDE; CARBON; DEUTERIUM; FENRETINIDE; LIPOFUSCIN; RETINAL; RETINOL ACETATE; RETINOL BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DRUG STRUCTURE; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; WILD TYPE;

RODENTIA;

EID: 79953145921     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.178640     Document Type: Article

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