-
1
-
-
77958072667
-
PGC-1 α, a potential therapeutic target for early intervention in Parkinson's disease
-
20926834 Epub 2010/10/12, PubMed Central PMCID: PMC3129986
-
Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, et al. PGC-1 α, a potential therapeutic target for early intervention in Parkinson's disease. SciTransl Med. 2010;2(52):52ra73. Epub 2010/10/12. doi: 10.1126/scitranslmed.3001059 PMID: 20926834; PubMed Central PMCID: PMC3129986.
-
(2010)
SciTransl Med.
, vol.2
, Issue.52
, pp. 52ra73
-
-
Zheng, B.1
Liao, Z.2
Locascio, J.J.3
Lesniak, K.A.4
Roderick, S.S.5
Watt, M.L.6
-
2
-
-
84920920653
-
Mutual exacerbation of peroxisome proliferator-activated receptor gamma coactivator 1a deregulation and α-synuclein oligomerization
-
25363075 PubMed Central PMCID: PMC4293280
-
Eschbach J, von Einem B, Muller K, Bayer H, Scheffold A, Morrison BE, et al. Mutual exacerbation of peroxisome proliferator-activated receptor gamma coactivator 1a deregulation and α-synuclein oligomerization. Annals of neurology. 2015;77(1):15-32. doi: 10.1002/ana.24294 PMID: 25363075; PubMed Central PMCID: PMC4293280.
-
(2015)
Annals of Neurology
, vol.77
, Issue.1
, pp. 15-32
-
-
Eschbach, J.1
Von Einem, B.2
Muller, K.3
Bayer, H.4
Scheffold, A.5
Morrison, B.E.6
-
3
-
-
33845596500
-
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
-
17018837
-
Handschin C, Spiegelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocrine reviews. 2006;27(7):728-35. doi: 10.1210/er. 2006-0037 PMID: 17018837.
-
(2006)
Endocrine reviews.
, vol.27
, Issue.7
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
4
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
16054085
-
Lin J, Handschin C, Spiegelman BM. Metabolic control through the PGC-1 family of transcription coactivators. Cell metabolism. 2005;1(6):361-70. doi: 10.1016/j.cmet.2005.05.004 PMID: 16054085.
-
(2005)
Cell Metabolism
, vol.1
, Issue.6
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
5
-
-
33744905787
-
PGC-1 α: A potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes
-
16752166
-
Soyal S, Krempler F, Oberkofler H, Patsch W. PGC-1 α: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes. Diabetologia. 2006;49(7):1477-88. doi: 10.1007/s00125-006-0268-6 PMID: 16752166.
-
(2006)
Diabetologia
, vol.49
, Issue.7
, pp. 1477-1488
-
-
Soyal, S.1
Krempler, F.2
Oberkofler, H.3
Patsch, W.4
-
6
-
-
33749042331
-
Transcriptional repression of PGC-1 a by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
17018277 Epub 2006/10/05
-
Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, Krainc D. Transcriptional repression of PGC-1 a by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell. 2006;127(1):59-69. Epub 2006/10/05. doi: 10.1016/j.cell.2006.09.015 PMID: 17018277.
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
7
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
17055439 Epub 2006/10/24
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jager S, et al. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell. 2006;127(2):397-408. Epub 2006/10/24. doi: 10.1016/j.cell.2006.09.024 PMID: 17055439.
-
(2006)
Cell
, vol.127
, Issue.2
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
-
8
-
-
33750437278
-
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1 a in Huntington's disease neurodegeneration
-
17055784 Epub 2006/10/24
-
Weydt P, Pineda VV, Torrence AE, Libby RT, Satterfield TF, Lazarowski ER, et al. Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1 a in Huntington's disease neurodegeneration. Cell metabolism. 2006;4(5):349-62. Epub 2006/10/24. doi: 10.1016/j.cmet. 2006.10.004 PMID: 17055784.
-
(2006)
Cell Metabolism
, vol.4
, Issue.5
, pp. 349-362
-
-
Weydt, P.1
Pineda, V.V.2
Torrence, A.E.3
Libby, R.T.4
Satterfield, T.F.5
Lazarowski, E.R.6
-
9
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
2557792 Epub 1989/12/01
-
Parker WD Jr., Boyson SJ, Parks JK. Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Annals of neurology. 1989;26(6):719-23. Epub 1989/12/01. doi: 10.1002/ana. 410260606 PMID: 2557792.
-
(1989)
Annals of Neurology
, vol.26
, Issue.6
, pp. 719-723
-
-
Parker Jr, . W.D.1
Boyson, S.J.2
Parks, J.K.3
-
10
-
-
0028316759
-
Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease
-
Epub 1994/03/14. 8047266
-
Janetzky B, Hauck S, Youdim MB, Riederer P, Jellinger K, Pantucek F, et al. Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease. Neurosci Lett. 1994;169(1-2):126-8. Epub 1994/03/14. PMID: 8047266.
-
(1994)
Neurosci Lett
, vol.169
, Issue.1-2
, pp. 126-128
-
-
Janetzky, B.1
Hauck, S.2
Youdim, M.B.3
Riederer, P.4
Jellinger, K.5
Pantucek, F.6
-
11
-
-
84894039470
-
Fatty acids and epigenetics
-
24322369 Epub 2013/12/11
-
Burdge GC, Lillycrop KA. Fatty acids and epigenetics. CurrOpin Clin NutrMetab Care. 2014;17(2):156-61. Epub 2013/12/11. doi: 10.1097/MCO.0000000000000023 PMID: 24322369.
-
(2014)
CurrOpin Clin NutrMetab Care
, vol.17
, Issue.2
, pp. 156-161
-
-
Burdge, G.C.1
Lillycrop, K.A.2
-
12
-
-
0030051986
-
Dietary lipids and antioxidants in Parkinson's disease: A population-based, case-control study
-
8572672 Epub 1996/01/01
-
Logroscino G, Marder K, Cote L, Tang MX, Shea S, Mayeux R. Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study. Annals of neurology. 1996;39(1):89-94. Epub 1996/01/01. doi: 10.1002/ana.410390113 PMID: 8572672.
-
(1996)
Annals of Neurology
, vol.39
, Issue.1
, pp. 89-94
-
-
Logroscino, G.1
Marder, K.2
Cote, L.3
Tang, M.X.4
Shea, S.5
Mayeux, R.6
-
13
-
-
0037675047
-
Dietary intakes of fat and risk of Parkinson's disease
-
Epub 2003/06/05. 12777364
-
Chen H, Zhang SM, Hernan MA, Willett WC, Ascherio A. Dietary intakes of fat and risk of Parkinson's disease. Am J Epidemiol. 2003;157(11):1007-14. Epub 2003/06/05. PMID: 12777364.
-
(2003)
Am J Epidemiol.
, vol.157
, Issue.11
, pp. 1007-1014
-
-
Chen, H.1
Zhang, S.M.2
Hernan, M.A.3
Willett, W.C.4
Ascherio, A.5
-
14
-
-
77957575432
-
Neurodegeneration in an animal model of Parkinson's disease is exacerbated by a high-fat diet
-
20702796 Epub 2010/08/13, PubMed Central PMCID: PMC2957375
-
Morris JK, Bomhoff GL, Stanford JA, Geiger PC. Neurodegeneration in an animal model of Parkinson's disease is exacerbated by a high-fat diet. Am J Physiol Regul Integr Comp Physiol. 2010;299(4):R1082-90. Epub 2010/08/13. doi: 10.1152/ajpregu.00449.2010 PMID: 20702796; PubMed Central PMCID: PMC2957375.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.299
, Issue.4
, pp. R1082-R1090
-
-
Morris, J.K.1
Bomhoff, G.L.2
Stanford, J.A.3
Geiger, P.C.4
-
15
-
-
84861670989
-
Targeting metabolic inflammation in Parkinson's disease: Implications for prospective therapeutic strategies
-
22126374 Epub 2011/12/01
-
Lu M, Hu G. Targeting metabolic inflammation in Parkinson's disease: implications for prospective therapeutic strategies. Clin Exp Pharmacol Physiol. 2012;39(6):577-85. Epub 2011/12/01. doi: 10.1111/j. 1440-1681.2011.05650.x PMID: 22126374.
-
(2012)
Clin Exp Pharmacol Physiol.
, vol.39
, Issue.6
, pp. 577-585
-
-
Lu, M.1
Hu, G.2
-
16
-
-
84875235515
-
Shared dysregulated pathways lead to Parkinson's disease and diabetes
-
23375873 Epub 2013/02/05
-
Santiago JA, Potashkin JA. Shared dysregulated pathways lead to Parkinson's disease and diabetes. Trends Mol Med. 2013;19(3):176-86. Epub 2013/02/05. doi: 10.1016/j.molmed.2013.01.002 PMID: 23375873.
-
(2013)
Trends Mol Med.
, vol.19
, Issue.3
, pp. 176-186
-
-
Santiago, J.A.1
Potashkin, J.A.2
-
17
-
-
34147190028
-
Type 2 diabetes and the risk of Parkinson's disease
-
17251276 Epub 2007/01/26
-
Hu G, Jousilahti P, Bidel S, Antikainen R, Tuomilehto J. Type 2 diabetes and the risk of Parkinson's disease. Diabetes Care. 2007;30(4):842-7. Epub 2007/01/26. doi: 10.2337/dc06-2011 PMID: 17251276.
-
(2007)
Diabetes Care.
, vol.30
, Issue.4
, pp. 842-847
-
-
Hu, G.1
Jousilahti, P.2
Bidel, S.3
Antikainen, R.4
Tuomilehto, J.5
-
18
-
-
79956361541
-
Association of blood pressure and hypertension with the risk of Parkinson disease: The National FINRISK Study
-
21536985 Epub 2011/05/04
-
Qiu C, Hu G, Kivipelto M, Laatikainen T, Antikainen R, Fratiglioni L, et al. Association of blood pressure and hypertension with the risk of Parkinson disease: the National FINRISK Study. Hypertension. 2011;57(6):1094-100. Epub 2011/05/04. doi: 10.1161/HYPERTENSIONAHA.111.171249 PMID: 21536985.
-
(2011)
Hypertension
, vol.57
, Issue.6
, pp. 1094-1100
-
-
Qiu, C.1
Hu, G.2
Kivipelto, M.3
Laatikainen, T.4
Antikainen, R.5
Fratiglioni, L.6
-
19
-
-
84883554833
-
Head injury and risk of Parkinson disease: A systematic review and meta-analysis
-
23609436 Epub 2013/04/24
-
Jafari S, Etminan M, Aminzadeh F, Samii A. Head injury and risk of Parkinson disease: a systematic review and meta-analysis. Mov Disord. 2013;28(9):1222-9. Epub 2013/04/24. doi: 10.1002/mds. 25458 PMID: 23609436.
-
(2013)
Mov Disord
, vol.28
, Issue.9
, pp. 1222-1229
-
-
Jafari, S.1
Etminan, M.2
Aminzadeh, F.3
Samii, A.4
-
20
-
-
1842292110
-
Delayed phospholipid degradation in rat brain after traumatic brain injury
-
Epub 1997/07/01. 9202311
-
Homayoun P, Rodriguez de Turco EB, Parkins NE, Lane DC, Soblosky J, Carey ME, et al. Delayed phospholipid degradation in rat brain after traumatic brain injury. J Neurochem. 1997;69(1):199-205. Epub 1997/07/01. PMID: 9202311.
-
(1997)
J Neurochem
, vol.69
, Issue.1
, pp. 199-205
-
-
Homayoun, P.1
Rodriguez De Turco, E.B.2
Parkins, N.E.3
Lane, D.C.4
Soblosky, J.5
Carey, M.E.6
-
21
-
-
0032589129
-
Exercise-test Tc-99mtetrofosmin SPECT in patients with chronic ischemic left ventricular dysfunction: Direct comparison with Ti-201 reinjection
-
Epub 1999/06/29. 10385182
-
Nicolai E, Cuocolo A, Acampa W, Varrone A, Pace L, Salvatore M. Exercise-test Tc-99mtetrofosmin SPECT in patients with chronic ischemic left ventricular dysfunction: direct comparison with Ti-201 reinjection. J Nucl Cardiol. 1999;6(3):270-7. Epub 1999/06/29. PMID: 10385182.
-
(1999)
J Nucl Cardiol.
, vol.6
, Issue.3
, pp. 270-277
-
-
Nicolai, E.1
Cuocolo, A.2
Acampa, W.3
Varrone, A.4
Pace, L.5
Salvatore, M.6
-
22
-
-
77956363279
-
Increased brain fatty acid uptake in metabolic syndrome
-
20566663 Epub 2010/06/23, PubMed Central PMCID: PMC2927939
-
Karmi A, Iozzo P, Viljanen A, Hirvonen J, Fielding BA, Virtanen K, et al. Increased brain fatty acid uptake in metabolic syndrome. Diabetes. 2010;59(9):2171-7. Epub 2010/06/23. doi: 10.2337/db09-0138 PMID: 20566663; PubMed Central PMCID: PMC2927939.
-
(2010)
Diabetes
, vol.59
, Issue.9
, pp. 2171-2177
-
-
Karmi, A.1
Iozzo, P.2
Viljanen, A.3
Hirvonen, J.4
Fielding, B.A.5
Virtanen, K.6
-
23
-
-
0036245056
-
Behavioral and neurochemical effects of wild-type and mutated human α-synuclein in transgenic mice
-
05/16 ed2002
-
Richfield EK, Thiruchelvam MJ, Cory-Slechta DA, Wuertzer C, Gainetdinov RR, Caron MG, et al. Behavioral and neurochemical effects of wild-type and mutated human α-synuclein in transgenic mice. Exp Neurol. 2002/05/16 ed2002. p. 35-48.
-
(2002)
Exp Neurol.
, pp. 35-48
-
-
Richfield, E.K.1
Thiruchelvam, M.J.2
Cory-Slechta, D.A.3
Wuertzer, C.4
Gainetdinov, R.R.5
Caron, M.G.6
-
24
-
-
0034160109
-
MethTools-a toolbox to visualize and analyze DNA methylation data
-
Epub 2000/02/10., PubMed Central PMCID: PMC102603 10666443
-
Grunau C, Schattevoy R, Mache N, Rosenthal A. MethTools-a toolbox to visualize and analyze DNA methylation data. Nucleic Acids Res. 2000;28(5):1053-8. Epub 2000/02/10. PMID: 10666443; PubMed Central PMCID: PMC102603.
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.5
, pp. 1053-1058
-
-
Grunau, C.1
Schattevoy, R.2
Mache, N.3
Rosenthal, A.4
-
25
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
15461798 PubMed Central PMCID: PMC545600
-
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5(10):R80. doi: 10.1186/gb-2004-5-10-r80 PMID: 15461798; PubMed Central PMCID: PMC545600.
-
(2004)
Genome Biol.
, vol.5
, Issue.10
, pp. R80
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
Dudoit, S.6
-
26
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
12925520
-
Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4(2):249-64. doi: 10.1093/biostatistics/4.2.249 PMID: 12925520.
-
(2003)
Biostatistics.
, vol.4
, Issue.2
, pp. 249-264
-
-
Irizarry, R.A.1
Hobbs, B.2
Collin, F.3
Beazer-Barclay, Y.D.4
Antonellis, K.J.5
Scherf, U.6
-
27
-
-
41149090082
-
DNAmethylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
-
17878930 Epub 2007/09/20, PubMed Central PMCID: PMC1964879
-
Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, et al. DNAmethylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS One. 2007;2(9):e895. Epub 2007/09/20. doi: 10.1371/journal.pone.0000895 PMID: 17878930; PubMed Central PMCID: PMC1964879.
-
(2007)
PLoS One
, vol.2
, Issue.9
, pp. e895
-
-
Siegmund, K.D.1
Connor, C.M.2
Campan, M.3
Long, T.I.4
Weisenberger, D.J.5
Biniszkiewicz, D.6
-
28
-
-
45849127657
-
Intra-individual change overtime in DNA methylation with familial clustering
-
18577732 Epub 2008/06/26, PubMed Central PMCID: PMC2581898
-
Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, et al. Intra-individual change overtime in DNA methylation with familial clustering. JAMA. 2008;299(24):2877-83. Epub 2008/06/26. doi: 10.1001/jama.299.24.2877 PMID: 18577732; PubMed Central PMCID: PMC2581898.
-
(2008)
JAMA
, vol.299
, Issue.24
, pp. 2877-2883
-
-
Bjornsson, H.T.1
Sigurdsson, M.I.2
Fallin, M.D.3
Irizarry, R.A.4
Aspelund, T.5
Cui, H.6
-
29
-
-
0345189364
-
Yeast cells provide insight into osynuclein biology and pathobiology
-
14657500 Epub 2003/12/06, PubMed Central PMCID: PMC1780172
-
Outeiro TF, Lindquist S. Yeast cells provide insight into osynuclein biology and pathobiology. Science. 2003;302(5651):1772-5. Epub 2003/12/06. doi: 10.1126/science.1090439 PMID: 14657500; PubMed Central PMCID: PMC1780172.
-
(2003)
Science
, vol.302
, Issue.5651
, pp. 1772-1775
-
-
Outeiro, T.F.1
Lindquist, S.2
-
30
-
-
84877770648
-
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism
-
23460021
-
Salvado L, Coll T, Gomez-Foix AM, Salmeron E, Barroso E, Palomer X, et al. Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. Diabetologia. 2013;56(6):1372-82. doi: 10.1007/s00125-013-2867-3 PMID: 23460021.
-
(2013)
Diabetologia
, vol.56
, Issue.6
, pp. 1372-1382
-
-
Salvado, L.1
Coll, T.2
Gomez-Foix, A.M.3
Salmeron, E.4
Barroso, E.5
Palomer, X.6
-
31
-
-
79951812916
-
Telomere dysfunction induces metabolic and mitochondrial compromise
-
21307849 PubMed Central PMCID: PMC3741661
-
Sahin E, Colla S, Liesa M, Moslehi J, Muller FL, Guo M, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 2011;470(7334):359-65. doi: 10.1038/nature09787 PMID: 21307849; PubMed Central PMCID: PMC3741661.
-
(2011)
Nature
, vol.470
, Issue.7334
, pp. 359-365
-
-
Sahin, E.1
Colla, S.2
Liesa, M.3
Moslehi, J.4
Muller, F.L.5
Guo, M.6
-
32
-
-
84859159081
-
Transgenic expression and activation of PGC-1 a protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease
-
21984601 Epub 2011/10/11
-
Mudo G, Makela J, Di Liberto V, Tselykh TV, Olivieri M, Piepponen P, et al. Transgenic expression and activation of PGC-1 a protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease. Cellular and molecular life sciences: CMLS. 2012;69(7):1153-65. Epub 2011/10/11. doi: 10.1007/s00018-011-0850-z PMID: 21984601.
-
(2012)
Cellular and Molecular Life Sciences: CMLS
, vol.69
, Issue.7
, pp. 1153-1165
-
-
Mudo, G.1
Makela, J.2
Di Liberto, V.3
Tselykh, T.V.4
Olivieri, M.5
Piepponen, P.6
-
33
-
-
84892570159
-
Loss of Pgc-1a expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation
-
24280126 Epub 2013/11/28
-
Sczelecki S, Besse-Patin A, Abboud A, Kleiner S, Laznik-Bogoslavski D, Wrann CD, et al. Loss of Pgc-1a expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation. American journal of physiology Endocrinology and metabolism. 2014;306(2):E157-67. Epub 2013/11/28. doi: 10.1152/ajpendo.00578.2013 PMID: 24280126.
-
(2014)
American Journal of Physiology Endocrinology and Metabolism
, vol.306
, Issue.2
, pp. E157-E167
-
-
Sczelecki, S.1
Besse-Patin, A.2
Abboud, A.3
Kleiner, S.4
Laznik-Bogoslavski, D.5
Wrann, C.D.6
-
34
-
-
84965086726
-
Astroglial PGC-1a increases mitochondrial antioxidant capacity and suppresses inflammation: Implications for multiple sclerosis
-
25492529 PubMed Central PMCID: PMC4268800
-
Nijland PG, Witte ME, van Het Hof B, van der Pol S, Bauer J, Lassmann H, et al. Astroglial PGC-1a increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis. Acta neuropathologica communications. 2014;2(1):170. doi: 10.1186/s40478-014-0170-2 PMID: 25492529; PubMed Central PMCID: PMC4268800.
-
(2014)
Acta Neuropathologica Communications
, vol.2
, Issue.1
, pp. 170
-
-
Nijland, P.G.1
Witte, M.E.2
Van Het Hof, B.3
Van Der Pol, S.4
Bauer, J.5
Lassmann, H.6
-
35
-
-
70349795301
-
Harnessing immune alterations in neurodegenerative diseases
-
19840543
-
Bjorkqvist M, Wild EJ, Tabrizi SJ. Harnessing immune alterations in neurodegenerative diseases. Neuron. 2009;64(1):21-4. doi: 10.1016/j.neuron. 2009.09.034 PMID: 19840543.
-
(2009)
Neuron
, vol.64
, Issue.1
, pp. 21-24
-
-
Bjorkqvist, M.1
Wild, E.J.2
Tabrizi, S.J.3
-
36
-
-
84857331867
-
Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome
-
22341451 Epub 2012/02/22, PubMed Central PMCID: PMC3343639
-
Xie W, Barr CL, Kim A, Yue F, Lee AY, Eubanks J, et al. Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell. 2012;148(4):816-31. Epub 2012/02/22. doi: 10.1016/j.cell.2011.12.035 PMID: 22341451; PubMed Central PMCID: PMC3343639.
-
(2012)
Cell
, vol.148
, Issue.4
, pp. 816-831
-
-
Xie, W.1
Barr, C.L.2
Kim, A.3
Yue, F.4
Lee, A.Y.5
Eubanks, J.6
-
37
-
-
84879663784
-
Global epigenomic reconfiguration during mammalian brain development
-
23828890 Epub 2013/07/06, PubMed Central PMCID: PMC3785061
-
Lister R, Mukamel EA, Nery JR, Urich M, Puddifoot CA, Johnson ND, et al. Global epigenomic reconfiguration during mammalian brain development. Science. 2013;341(6146):1237905. Epub 2013/07/06. doi: 10.1126/science.1237905 PMID: 23828890; PubMed Central PMCID: PMC3785061.
-
(2013)
Science
, vol.341
, Issue.6146
, pp. 1237905
-
-
Lister, R.1
Mukamel, E.A.2
Nery, J.R.3
Urich, M.4
Puddifoot, C.A.5
Johnson, N.D.6
-
38
-
-
84893740377
-
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain
-
24362762 Epub 2013/12/24
-
Guo JU, Su Y, Shin JH, Shin J, Li H, Xie B, et al. Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nat Neurosci. 2014;17(2):215-22. Epub 2013/12/24. doi: 10.1038/nn. 3607 PMID: 24362762.
-
(2014)
Nat Neurosci
, vol.17
, Issue.2
, pp. 215-222
-
-
Guo, J.U.1
Su, Y.2
Shin, J.H.3
Shin, J.4
Li, H.5
Xie, B.6
-
39
-
-
84874624739
-
Dynamic DNA methylation across diverse human cell lines and tissues
-
23325432 Epub 2013/01/18, PubMed Central PMCID: PMC3589544
-
Varley KE, Gertz J, Bowling KM, Parker SL, Reddy TE, Pauli-Behn F, et al. Dynamic DNA methylation across diverse human cell lines and tissues. Genome Res. 2013;23(3):555-67. Epub 2013/01/18. doi: 10.1101/gr.147942.112 PMID: 23325432; PubMed Central PMCID: PMC3589544.
-
(2013)
Genome Res.
, vol.23
, Issue.3
, pp. 555-567
-
-
Varley, K.E.1
Gertz, J.2
Bowling, K.M.3
Parker, S.L.4
Reddy, T.E.5
Pauli-Behn, F.6
-
40
-
-
0032901199
-
Cytosine methylation and mammalian development
-
Epub 1999/01/14., PubMed Central PMCID: PMC316374 9887097
-
Walsh CP, Bestor TH. Cytosine methylation and mammalian development. Genes Dev. 1999;13(1):26-34. Epub 1999/01/14. PMID: 9887097; PubMed Central PMCID: PMC316374.
-
(1999)
Genes Dev.
, vol.13
, Issue.1
, pp. 26-34
-
-
Walsh, C.P.1
Bestor, T.H.2
-
41
-
-
31344466008
-
DNA methylation and gene silencing in cancer
-
16341240 Epub 2005/12/13
-
Baylin SB. DNA methylation and gene silencing in cancer. Nat Clin Pract Oncol. 2005;2 Suppl 1:S4-11. Epub 2005/12/13. doi: 10.1038/ncponc0354 PMID: 16341240.
-
(2005)
Nat Clin Pract Oncol.
, vol.2
, pp. S4-S11
-
-
Baylin, S.B.1
-
42
-
-
9144256125
-
The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites
-
15339928 Epub 2004/09/02
-
Hermann A, Goyal R, Jeltsch A. The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites. J Biol Chem. 2004;279(46):48350-9. Epub 2004/09/02. doi: 10.1074/jbc. M403427200 PMID: 15339928.
-
(2004)
J Biol Chem.
, vol.279
, Issue.46
, pp. 48350-48359
-
-
Hermann, A.1
Goyal, R.2
Jeltsch, A.3
-
43
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
-
20228804 Epub 2010/03/17, PubMed Central PMCID: PMC3060772
-
Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, et al. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci. 2010;13(4):423-30. Epub 2010/03/17. doi: 10.1038/nn. 2514 PMID: 20228804; PubMed Central PMCID: PMC3060772.
-
(2010)
Nat Neurosci.
, vol.13
, Issue.4
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
Le, T.4
Li, E.5
Sweatt, J.D.6
-
44
-
-
16444381345
-
Dynamic expression of de novo DNAmethyltransferases Dnmt3aand Dnmt3b in the central nervous system
-
15672446 Epub 2005/01/27
-
Feng J, Chang H, Li E, Fan G. Dynamic expression of de novo DNAmethyltransferases Dnmt3aand Dnmt3b in the central nervous system. J Neurosci Res. 2005;79(6):734-46. Epub 2005/01/27. doi: 10. 1002/jnr.20404 PMID: 15672446.
-
(2005)
J Neurosci Res.
, vol.79
, Issue.6
, pp. 734-746
-
-
Feng, J.1
Chang, H.2
Li, E.3
Fan, G.4
-
45
-
-
81255143014
-
Epigenetic regulation of motor neuron cell death through DNA methylation
-
22090490 Epub 2011/11/18, PubMed Central PMCID: PMC3238138
-
Chestnut BA, Chang Q, Price A, Lesuisse C, Wong M, Martin LJ. Epigenetic regulation of motor neuron cell death through DNA methylation. J Neurosci. 2011;31(46):16619-36. Epub 2011/11/18. doi: 10. 1523/JNEUROSCI.1639-11.2011 PMID: 22090490; PubMed Central PMCID: PMC3238138.
-
(2011)
J Neurosci.
, vol.31
, Issue.46
, pp. 16619-16636
-
-
Chestnut, B.A.1
Chang, Q.2
Price, A.3
Lesuisse, C.4
Wong, M.5
Martin, L.J.6
-
46
-
-
0037102256
-
Transcriptional co-activator PGC-1 α drives the formation of slow-twitch muscle fibres
-
12181572 Epub 2002/08/16
-
Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, et al. Transcriptional co-activator PGC-1 α drives the formation of slow-twitch muscle fibres. Nature. 2002;418(6899):797-801. Epub 2002/08/16. doi: 10. 1038/nature00904 PMID: 12181572.
-
(2002)
Nature.
, vol.418
, Issue.6899
, pp. 797-801
-
-
Lin, J.1
Wu, H.2
Tarr, P.T.3
Zhang, C.Y.4
Wu, Z.5
Boss, O.6
-
47
-
-
50049118173
-
Activation of the PPAR/PGC-1 α pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype
-
18762025 Epub 2008/09/03, PubMed Central PMCID: PMC2613643
-
Wenz T, Diaz F, Spiegelman BM, Moraes CT. Activation of the PPAR/PGC-1 α pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype. Cell metabolism. 2008;8(3):249-56. Epub 2008/09/03. doi: 10.1016/j.cmet.2008.07.006 PMID: 18762025; PubMed Central PMCID: PMC2613643.
-
(2008)
Cell Metabolism
, vol.8
, Issue.3
, pp. 249-256
-
-
Wenz, T.1
Diaz, F.2
Spiegelman, B.M.3
Moraes, C.T.4
-
48
-
-
78751529597
-
Mitochondrial biogenesis and peroxisome proliferator-activated receptor-gamma coactivator-1 a (PGC-1 a) deacetylation by physical activity: Intact adipocytokine signaling is required
-
20929977 PubMed Central PMCID: PMC3012167
-
Li L, Pan R, Li R, Niemann B, Aurich AC, Chen Y, et al. Mitochondrial biogenesis and peroxisome proliferator-activated receptor-gamma coactivator-1 a (PGC-1 a) deacetylation by physical activity: intact adipocytokine signaling is required. Diabetes. 2011;60(1):157-67. doi: 10.2337/db10-0331 PMID: 20929977; PubMed Central PMCID: PMC3012167.
-
(2011)
Diabetes
, vol.60
, Issue.1
, pp. 157-167
-
-
Li, L.1
Pan, R.2
Li, R.3
Niemann, B.4
Aurich, A.C.5
Chen, Y.6
-
49
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Epub 1999/07/21, PMID: 10412986
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 1999;98(1):115-24. Epub 1999/07/21. doi: 10.1016/S0092-8674 (00) 80611-X PMID: 10412986.
-
(1999)
Cell
, vol.98
, Issue.1
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
-
50
-
-
84873880480
-
The peroxisome proliferator-activated receptor gamma coactivator 1 α/beta (PGC-1) coactivators repress the transcriptional activity of NF-kappaB in skeletal muscle cells
-
23223635 Epub 2012/12/12, PubMed Central PMCID: PMC3554897
-
Eisele PS, Salatino S, Sobek J, Hottiger MO, Handschin C. The peroxisome proliferator-activated receptor gamma coactivator 1 α/beta (PGC-1) coactivators repress the transcriptional activity of NF-kappaB in skeletal muscle cells. J BiolChem. 2013;288(4):2246-60. Epub 2012/12/12. doi: 10.1074/jbc. M112.375253 PMID: 23223635; PubMed Central PMCID: PMC3554897.
-
(2013)
J BiolChem
, vol.288
, Issue.4
, pp. 2246-2260
-
-
Eisele, P.S.1
Salatino, S.2
Sobek, J.3
Hottiger, M.O.4
Handschin, C.5
-
51
-
-
19444365211
-
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
-
15914121 Epub 2005/05/26
-
Valle I, Alvarez-Barrientos A, Arza E, Lamas S, Monsalve M. PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc Res. 2005;66(3):562-73. Epub 2005/05/26. doi: 10.1016/j.cardiores.2005.01.026 PMID: 15914121.
-
(2005)
Cardiovasc Res.
, vol.66
, Issue.3
, pp. 562-573
-
-
Valle, I.1
Alvarez-Barrientos, A.2
Arza, E.3
Lamas, S.4
Monsalve, M.5
-
52
-
-
79952303794
-
Paris (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease
-
21376232 PubMed Central PMCID: PMC3063894
-
Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, et al. PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease. Cell. 2011;144(5):689-702. doi: 10.1016/j. cell.2011.02.010 PMID: 21376232; PubMed Central PMCID: PMC3063894.
-
(2011)
Cell.
, vol.144
, Issue.5
, pp. 689-702
-
-
Shin, J.H.1
Ko, H.S.2
Kang, H.3
Lee, Y.4
Lee, Y.I.5
Pletinkova, O.6
-
53
-
-
64549127790
-
PGC-1α, SIRT1 and AMPK, an energy sensing networkthat controls energy expenditure
-
19276888 Epub 2009/03/12, PubMed Central PMCID: PMC3627054
-
Canto C, Auwerx J. PGC-1α, SIRT1 and AMPK, an energy sensing networkthat controls energy expenditure. CurrOpin Lipidol. 2009;20(2):98-105. Epub 2009/03/12. doi: 10.1097/MOL 0b013e328328d0a4 PMID: 19276888; PubMed Central PMCID: PMC3627054.
-
(2009)
CurrOpin Lipidol.
, vol.20
, Issue.2
, pp. 98-105
-
-
Canto, C.1
Auwerx, J.2
-
54
-
-
84895797258
-
Evidence for the role of AMPK in regulating PGC-1 a expression and mitochondrial proteins in mouse epididymal adipose tissue
-
23963743 Epub 2013/08/22
-
Wan Z, Root-McCaig J, Castellani L, Kemp BE, Steinberg GR, Wright DC. Evidence for the role of AMPK in regulating PGC-1 a expression and mitochondrial proteins in mouse epididymal adipose tissue. Obesity (Silver Spring). 2014;22(3):730-8. Epub 2013/08/22. doi: 10.1002/oby.20605 PMID: 23963743.
-
(2014)
Obesity (Silver Spring)
, vol.22
, Issue.3
, pp. 730-738
-
-
Wan, Z.1
Root-McCaig, J.2
Castellani, L.3
Kemp, B.E.4
Steinberg, G.R.5
Wright, D.C.6
-
55
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
12971891
-
Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron. 2003;39(6):889-909. PMID: 12971891.
-
(2003)
Neuron.
, vol.39
, Issue.6
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
56
-
-
84910116996
-
Palmitic acid-induced neuron cell cycle G2/M arrest and endoplasmic reticular stress through protein palmitoylation in SH-SY5Y human neuroblastoma cells
-
25402647 PubMed Central PMCID: PMC4264201
-
Hsiao YH, Lin CI, Liao H, Chen YH, Lin SH. Palmitic acid-induced neuron cell cycle G2/M arrest and endoplasmic reticular stress through protein palmitoylation in SH-SY5Y human neuroblastoma cells. International journal of molecular sciences. 2014;15(11):20876-99. doi: 10.3390/ijms151120876 PMID: 25402647; PubMed Central PMCID: PMC4264201.
-
(2014)
International Journal of Molecular Sciences
, vol.15
, Issue.11
, pp. 20876-20899
-
-
Hsiao, Y.H.1
Lin, C.I.2
Liao, H.3
Chen, Y.H.4
Lin, S.H.5
-
57
-
-
84861910718
-
A role for aberrant protein palmitoylation in FFA-induced ER stress and beta-cell death
-
22436701 PubMed Central PMCID: PMC3378068
-
Baldwin AC, Green CD, Olson LK, Moxley MA, Corbett JA. A role for aberrant protein palmitoylation in FFA-induced ER stress and beta-cell death. American journal of physiology Endocrinology and metabolism. 2012;302(11):E1390-8. doi: 10.1152/ajpendo.00519.2011 PMID: 22436701; PubMed Central PMCID: PMC3378068.
-
(2012)
American Journal of Physiology Endocrinology and Metabolism
, vol.302
, Issue.11
, pp. E1390-E1398
-
-
Baldwin, A.C.1
Green, C.D.2
Olson, L.K.3
Moxley, M.A.4
Corbett, J.A.5
-
58
-
-
45549093249
-
The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response
-
18319256
-
Bartoszewski R, Rab A, Twitty G, Stevenson L, Fortenberry J, Piotrowski A, et al. The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response. J Biol Chem. 2008;283(18):12154-65. doi: 10.1074/jbc. M707610200 PMID: 18319256.
-
(2008)
J Biol Chem.
, vol.283
, Issue.18
, pp. 12154-12165
-
-
Bartoszewski, R.1
Rab, A.2
Twitty, G.3
Stevenson, L.4
Fortenberry, J.5
Piotrowski, A.6
-
59
-
-
8644282751
-
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
-
15542827 PubMed Central PMCID: PMC529034
-
Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, et al. Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol. 2004;24(23):10161-8. doi: 10.1128/MCB.24.23.10161-10168.2004 PMID: 15542827; PubMed Central PMCID: PMC529034.
-
(2004)
Mol Cell Biol.
, vol.24
, Issue.23
, pp. 10161-10168
-
-
Deng, J.1
Lu, P.D.2
Zhang, Y.3
Scheuner, D.4
Kaufman, R.J.5
Sonenberg, N.6
-
60
-
-
33645815074
-
Autocrine tumor necrosis factorα links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
16581782 PubMed Central PMCID: PMC1446932
-
Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. Autocrine tumor necrosis factorα links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol Cell Biol. 2006;26(8):3071-84. doi: 10.1128/MCB.26.8.3071-3084.2006 PMID: 16581782; PubMed Central PMCID: PMC1446932.
-
(2006)
Mol Cell Biol.
, vol.26
, Issue.8
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
61
-
-
69149087790
-
Non-CpG methylationofthe PGC-1αpromoterthrough DNMT3B controls mitochondrial density
-
19723495 Epub 2009/09/03
-
Barres R, Osler ME, Yan J, Rune A, Fritz T, Caidahl K, et al. Non-CpG methylationofthe PGC-1αpromoterthrough DNMT3B controls mitochondrial density. Cell metabolism. 2009;10(3):189-98. Epub 2009/09/03. doi: 10.1016/j.cmet.2009.07.011 PMID: 19723495.
-
(2009)
Cell metabolism.
, vol.10
, Issue.3
, pp. 189-198
-
-
Barres, R.1
Osler, M.E.2
Yan, J.3
Rune, A.4
Fritz, T.5
Caidahl, K.6
|