메뉴 건너뛰기




Volumn 10, Issue 8, 2015, Pages

Identifying the critical domain of LL-37 involved in mediating neutrophil activation in the presence of influenza virus: Functional and structural analysis

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR 2; GI 20; INTERLEUKIN 8; LL 23; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; FPR2 PROTEIN, HUMAN; LIPOXIN RECEPTOR; PEPTIDE FRAGMENT;

EID: 84943339177     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133454     Document Type: Article
Times cited : (24)

References (51)
  • 1
    • 84914145530 scopus 로고    scopus 로고
    • The amazing innate immune response to influenza A virus infection
    • PMID: 24217220
    • Tripathi S, White MR, Hartshorn KL. The amazing innate immune response to influenza A virus infection. Innate Immun. 2015; 21(1):73-98. doi: 10.1177/1753425913508992 PMID: 24217220.
    • (2015) Innate Immun , vol.21 , Issue.1 , pp. 73-98
    • Tripathi, S.1    White, M.R.2    Hartshorn, K.L.3
  • 2
    • 20544442905 scopus 로고    scopus 로고
    • Alarmins: Chemotactic activators of immune responses
    • PMID: 15955682
    • Oppenheim JJ, Yang D. Alarmins: chemotactic activators of immune responses. Curr Opin Immunol. 2005; 17(4):359-65. PMID: 15955682.
    • (2005) Curr Opin Immunol , vol.17 , Issue.4 , pp. 359-365
    • Oppenheim, J.J.1    Yang, D.2
  • 3
    • 84885142548 scopus 로고    scopus 로고
    • Cationic host defence peptides: Potential as antiviral therapeutics
    • PMID: 23649937
    • Gwyer Findlay E, Currie SM, Davidson DJ. Cationic Host Defence Peptides: Potential as Antiviral Therapeutics. BioDrugs. 2013. PMID: 23649937.
    • (2013) BioDrugs
    • Gwyer Findlay, E.1    Currie, S.M.2    Davidson, D.J.3
  • 4
    • 77950605506 scopus 로고    scopus 로고
    • Recombinant mouse beta-defensin 2 inhibits infection by influenza A virus by blocking its entry
    • PMID: 20195655
    • Gong T, Jiang Y, Wang Y, Yang D, Li W, Zhang Q, et al. Recombinant mouse beta-defensin 2 inhibits infection by influenza A virus by blocking its entry. Arch Virol. 2010; 155(4):491-8. PMID: 20195655.doi: 10.1007/s00705-010-0608-1
    • (2010) Arch Virol , vol.155 , Issue.4 , pp. 491-498
    • Gong, T.1    Jiang, Y.2    Wang, Y.3    Yang, D.4    Li, W.5    Zhang, Q.6
  • 5
    • 64249114517 scopus 로고    scopus 로고
    • Expression of mouse beta-defensin-3 in MDCK cells and its anti-influenza-virus activity
    • PMID: 19301094
    • Jiang Y, Wang Y, Kuang Y, Wang B, Li W, Gong T, et al. Expression of mouse beta-defensin-3 in MDCK cells and its anti-influenza-virus activity. Arch Virol. 2009; 154(4):639-47. PMID: 19301094. doi: 10.1007/s00705-009-0352-6
    • (2009) Arch Virol , vol.154 , Issue.4 , pp. 639-647
    • Jiang, Y.1    Wang, Y.2    Kuang, Y.3    Wang, B.4    Li, W.5    Gong, T.6
  • 6
    • 34548480179 scopus 로고    scopus 로고
    • Alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s)
    • PMID: 17703413
    • Salvatore M, Garcia-Sastre A, Ruchala P, Lehrer RI, Chang T, Klotman ME. alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s). J Infect Dis. 2007; 196(6):835-43. PMID: 17703413.
    • (2007) J Infect Dis , vol.196 , Issue.6 , pp. 835-843
    • Salvatore, M.1    Garcia-Sastre, A.2    Ruchala, P.3    Lehrer, R.I.4    Chang, T.5    Klotman, M.E.6
  • 7
    • 27144511726 scopus 로고    scopus 로고
    • Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins
    • PMID: 16155572
    • Leikina E, Delanoe-Ayari H, Melikov K, Cho MS, Chen A, Waring AJ, et al. Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins. Nat Immunol. 2005; 6 (10):995-1001. PMID: 16155572.
    • (2005) Nat Immunol , vol.6 , Issue.10 , pp. 995-1001
    • Leikina, E.1    Delanoe-Ayari, H.2    Melikov, K.3    Cho, M.S.4    Chen, A.5    Waring, A.J.6
  • 8
    • 84871300505 scopus 로고    scopus 로고
    • The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins
    • PMID: 23052388; PubMed Central PMCID: PMC3542722
    • Tripathi S, Tecle T, Verma A, Crouch E, White M, Hartshorn KL. The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins. J Gen Virol. 2013; 94(Pt 1):40-9. doi: 10.1099/vir.0.045013-0 PMID: 23052388; PubMed Central PMCID: PMC3542722.
    • (2013) J Gen Virol , vol.94 , pp. 40-49
    • Tripathi, S.1    Tecle, T.2    Verma, A.3    Crouch, E.4    White, M.5    Hartshorn, K.L.6
  • 9
    • 67649160595 scopus 로고    scopus 로고
    • Interactions of alpha-, beta-, and thetadefensins with influenza A virus and surfactant protein D
    • PMID: 19494312
    • Doss M, White MR, Tecle T, Gantz D, Crouch EC, Jung G, et al. Interactions of alpha-, beta-, and thetadefensins with influenza A virus and surfactant protein D. J Immunol. 2009; 182(12):7878-87. PMID: 19494312. doi: 10.4049/jimmunol.0804049
    • (2009) J Immunol , vol.182 , Issue.12 , pp. 7878-7887
    • Doss, M.1    White, M.R.2    Tecle, T.3    Gantz, D.4    Crouch, E.C.5    Jung, G.6
  • 10
    • 33646898488 scopus 로고    scopus 로고
    • Innate defense against influenza A virus: Activity of human neutrophil defensins and interactions of defensins with surfactant protein D
    • PMID: 16709857
    • Hartshorn KL, White MR, Tecle T, Holmskov U, Crouch EC. Innate defense against influenza A virus: activity of human neutrophil defensins and interactions of defensins with surfactant protein D. J Immunol. 2006; 176(11):6962-72. PMID: 16709857.
    • (2006) J Immunol , vol.176 , Issue.11 , pp. 6962-6972
    • Hartshorn, K.L.1    White, M.R.2    Tecle, T.3    Holmskov, U.4    Crouch, E.C.5
  • 11
    • 0019297043 scopus 로고
    • Pathogenicity of influenza virus
    • PMID: 6991901
    • Sweet C, Smith H. Pathogenicity of influenza virus. Microbiol Rev. 1980; 44:303-30. PMID: 6991901
    • (1980) Microbiol Rev , vol.44 , pp. 303-330
    • Sweet, C.1    Smith, H.2
  • 12
    • 80054841451 scopus 로고    scopus 로고
    • Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37
    • PMID: 22031815
    • Barlow PG, Svoboda P, Mackellar A, Nash AA, York IA, Pohl J, et al. Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37. PLoS One. 2011; 6 (10):e25333. PMID: 22031815. doi: 10.1371/journal.pone.0025333
    • (2011) PLoS One , vol.6 , Issue.10 , pp. e25333
    • Barlow, P.G.1    Svoboda, P.2    Mackellar, A.3    Nash, A.A.4    York, I.A.5    Pohl, J.6
  • 13
    • 44449122937 scopus 로고    scopus 로고
    • Leukotriene B4 induces release of antimicrobial peptides in lungs of virally infected mice
    • PMID: 18424743
    • Gaudreault E, Gosselin J. Leukotriene B4 induces release of antimicrobial peptides in lungs of virally infected mice. J Immunol. 2008; 180(9):6211-21. PMID: 18424743 .
    • (2008) J Immunol , vol.180 , Issue.9 , pp. 6211-6221
    • Gaudreault, E.1    Gosselin, J.2
  • 14
    • 74949124734 scopus 로고    scopus 로고
    • Human defensins and LL-37 in mucosal immunity
    • PMID: 19808939
    • Doss M, White MR, Tecle T, Hartshorn KL. Human defensins and LL-37 in mucosal immunity. J Leukoc Biol. 2010; 87:79-92. PMID: 19808939. doi: 10.1189/jlb.0609382
    • (2010) J Leukoc Biol , vol.87 , pp. 79-92
    • Doss, M.1    White, M.R.2    Tecle, T.3    Hartshorn, K.L.4
  • 15
    • 70349635632 scopus 로고    scopus 로고
    • Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages
    • PMID: 19581375; PubMed Central PMCID: PMC2791992
    • Li HN, Barlow PG, Bylund J, Mackellar A, Bjorstad A, Conlon J, et al. Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages. J Leukoc Biol. 2009; 86(4):891-902. doi: 10.1189/jlb.0209050 PMID: 19581375; PubMed Central PMCID: PMC2791992.
    • (2009) J Leukoc Biol , vol.86 , Issue.4 , pp. 891-902
    • Li, H.N.1    Barlow, P.G.2    Bylund, J.3    Mackellar, A.4    Bjorstad, A.5    Conlon, J.6
  • 16
    • 34250204072 scopus 로고    scopus 로고
    • Human neutrophil defensins increase neutrophil uptake of influenza A virus and bacteria and modify virus-induced respiratory burst responses
    • PMID: 17548642
    • Tecle T, White MR, Gantz D, Crouch EC, Hartshorn KL. Human neutrophil defensins increase neutrophil uptake of influenza A virus and bacteria and modify virus-induced respiratory burst responses. J Immunol. 2007; 178(12):8046-52. PMID: 17548642.
    • (2007) J Immunol , vol.178 , Issue.12 , pp. 8046-8052
    • Tecle, T.1    White, M.R.2    Gantz, D.3    Crouch, E.C.4    Hartshorn, K.L.5
  • 18
    • 33845383026 scopus 로고    scopus 로고
    • Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide
    • PMID: 16943385
    • Mookherjee N, Wilson HL, Doria S, Popowych Y, Falsafi R, Yu JJ, et al. Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide. J Leukoc Biol. 2006; 80(6):1563-74. PMID: 16943385.
    • (2006) J Leukoc Biol , vol.80 , Issue.6 , pp. 1563-1574
    • Mookherjee, N.1    Wilson, H.L.2    Doria, S.3    Popowych, Y.4    Falsafi, R.5    Yu, J.J.6
  • 19
    • 0034596945 scopus 로고    scopus 로고
    • LL-37, the neutrophil granuleand epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells
    • PMID: 11015447
    • De Y, Chen Q, Schmidt AP, Anderson GM, Wang JM, Wooters J, et al. LL-37, the neutrophil granuleand epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells. J Exp Med. 2000; 192 (7):1069-74. PMID: 11015447.
    • (2000) J Exp Med , vol.192 , Issue.7 , pp. 1069-1074
    • De Y Chen, Q.1    Schmidt, A.P.2    Anderson, G.M.3    Wang, J.M.4    Wooters, J.5
  • 20
    • 70149090684 scopus 로고    scopus 로고
    • Intracellular receptor for human host defense peptide LL-37 in monocytes
    • PMID: 19605696
    • Mookherjee N, Lippert DN, Hamill P, Falsafi R, Nijnik A, Kindrachuk J, et al. Intracellular receptor for human host defense peptide LL-37 in monocytes. J Immunol. 2009; 183(4):2688-96. PMID: 19605696. doi: 10.4049/jimmunol.0802586
    • (2009) J Immunol , vol.183 , Issue.4 , pp. 2688-2696
    • Mookherjee, N.1    Lippert, D.N.2    Hamill, P.3    Falsafi, R.4    Nijnik, A.5    Kindrachuk, J.6
  • 21
    • 70449363613 scopus 로고    scopus 로고
    • Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils
    • PMID: 19750480
    • Zhang Z, Cherryholmes G, Chang F, Rose DM, Schraufstatter I, Shively JE. Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils. Eur J Immunol. 2009; 39(11):3181-94. PMID: 19750480. doi: 10.1002/eji.200939496
    • (2009) Eur J Immunol , vol.39 , Issue.11 , pp. 3181-3194
    • Zhang, Z.1    Cherryholmes, G.2    Chang, F.3    Rose, D.M.4    Schraufstatter, I.5    Shively, J.E.6
  • 22
    • 0346996865 scopus 로고    scopus 로고
    • The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor
    • PMID: 14662872
    • Tjabringa GS, Aarbiou J, Ninaber DK, Drijfhout JW, Sorensen OE, Borregaard N, et al. The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor. J Immunol. 2003; 171(12):6690-6. PMID: 14662872.
    • (2003) J Immunol , vol.171 , Issue.12 , pp. 6690-6696
    • Tjabringa, G.S.1    Aarbiou, J.2    Ninaber, D.K.3    Drijfhout, J.W.4    Sorensen, O.E.5    Borregaard, N.6
  • 23
    • 33644511380 scopus 로고    scopus 로고
    • An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7
    • PMID: 16493063
    • Nagaoka I, Tamura H, Hirata M. An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7. J Immunol. 2006; 176(5):3044-52. PMID: 16493063.
    • (2006) J Immunol , vol.176 , Issue.5 , pp. 3044-3052
    • Nagaoka, I.1    Tamura, H.2    Hirata, M.3
  • 24
    • 1342282224 scopus 로고    scopus 로고
    • Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense
    • PMID: 14978112
    • Murakami M, Lopez-Garcia B, Braff M, Dorschner RA, Gallo RL. Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense. J Immunol. 2004; 172(5):3070-7. PMID: 14978112.
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 3070-3077
    • Murakami, M.1    Lopez-Garcia, B.2    Braff, M.3    Dorschner, R.A.4    Gallo, R.L.5
  • 25
    • 84877664994 scopus 로고    scopus 로고
    • Surface activity and structures of two fragments of the human antimicrobial LL-37
    • PMID: 23624281
    • Dannehl C, Gutsmann T, Brezesinski G. Surface activity and structures of two fragments of the human antimicrobial LL-37. Colloids and surfaces B, Biointerfaces. 2013; 109:129-35. doi: 10.1016/j.colsurfb.2013.03.030 PMID: 23624281.
    • (2013) Colloids and Surfaces B Biointerfaces , vol.109 , pp. 129-135
    • Dannehl, C.1    Gutsmann, T.2    Brezesinski, G.3
  • 26
    • 84872433200 scopus 로고    scopus 로고
    • Effect of antimicrobial peptides derived from human cathelicidin LL-37 on Entamoeba histolytica trophozoites
    • PMID: 23274811
    • Rico-Mata R, De Leon-Rodriguez LM, Avila EE. Effect of antimicrobial peptides derived from human cathelicidin LL-37 on Entamoeba histolytica trophozoites. Experimental parasitology. 2013; 133 (3):300-6. doi: 10.1016/j.exppara.2012.12.009 PMID: 23274811.
    • (2013) Experimental Parasitology , vol.133 , Issue.3 , pp. 300-306
    • Rico-Mata, R.1    De Leon-Rodriguez, L.M.2    Avila, E.E.3
  • 27
    • 84862907676 scopus 로고    scopus 로고
    • Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins
    • PMID: 22185690
    • Wang G, Elliott M, Cogen AL, Ezell EL, Gallo RL, Hancock RE. Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins. Biochemistry. 2012; 51(2):653-64. PMID: 22185690. doi: 10.1021/bi2016266
    • (2012) Biochemistry , vol.51 , Issue.2 , pp. 653-664
    • Wang, G.1    Elliott, M.2    Cogen, A.L.3    Ezell, E.L.4    Gallo, R.L.5    Hancock, R.E.6
  • 28
    • 57749088664 scopus 로고    scopus 로고
    • Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles
    • PMID: 18818205
    • Wang G. Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles. J Biol Chem. 2008; 283(47):32637-43. PMID: 18818205. doi: 10.1074/jbc.M805533200
    • (2008) J Biol Chem , vol.283 , Issue.47 , pp. 32637-32643
    • Wang, G.1
  • 29
    • 84912095002 scopus 로고    scopus 로고
    • Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds
    • PMID: 25061850; PubMed Central PMCID: PMC4168778
    • Wang G, Hanke ML, Mishra B, Lushnikova T, Heim CE, Chittezham Thomas V, et al. Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds. ACS chemical biology. 2014; 9(9):1997-2002. doi: 10.1021/cb500475y PMID: 25061850; PubMed Central PMCID: PMC4168778.
    • (2014) ACS Chemical Biology , vol.9 , Issue.9 , pp. 1997-2002
    • Wang, G.1    Hanke, M.L.2    Mishra, B.3    Lushnikova, T.4    Heim, C.E.5    Chittezham Thomas, V.6
  • 30
    • 84885934303 scopus 로고    scopus 로고
    • Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxicity
    • PMID: 24105706
    • Jacob B, Park IS, Bang JK, Shin SY. Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxicity. J Pept Sci. 2013; 19(11):700-7. doi: 10.1002/psc.2552 PMID: 24105706.
    • (2013) J Pept Sci , vol.19 , Issue.11 , pp. 700-707
    • Jacob, B.1    Park, I.S.2    Bang, J.K.3    Shin, S.Y.4
  • 31
    • 84903701599 scopus 로고
    • High-quality 3D structures shine light on antibacterial, antibiofilm and antiviral activities of human cathelicidin LL-37 and its fragments
    • PMID: 24463069; PubMed Central PMCID: PMC4082733
    • Wang G, Mishra B, Epand RF, Epand RM. High-quality 3D structures shine light on antibacterial, antibiofilm and antiviral activities of human cathelicidin LL-37 and its fragments. Biochim Biophys Acta. 2014; 1838(9):2160-72. doi: 10.1016/j.bbamem.2014.01.016 PMID: 24463069; PubMed Central PMCID: PMC4082733.
    • (1838) Biochim Biophys Acta , vol.2014 , Issue.9 , pp. 2160-2172
    • Wang, G.1    Mishra, B.2    Epand, R.F.3    Epand, R.M.4
  • 32
    • 84928902559 scopus 로고    scopus 로고
    • Antiviral activity of the human cathelicidin ll-37 and derived peptides on seasonal and pandemic influenza a viruses
    • PMID: 25909853; PubMed Central PMCID: PMC4409069
    • Tripathi S, Wang G, White M, Qi L, Taubenberger J, Hartshorn KL. Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses. PLoS One. 2015; 10(4):e0124706. doi: 10.1371/journal.pone.0124706 PMID: 25909853; PubMed Central PMCID: PMC4409069.
    • (2015) PLoS One , vol.10 , Issue.4 , pp. e0124706
    • Tripathi, S.1    Wang, G.2    White, M.3    Qi, L.4    Taubenberger, J.5    Hartshorn, K.L.6
  • 34
    • 0031416787 scopus 로고    scopus 로고
    • Mechanisms of anti-influenza activity of surfactant proteins A and D: Comparison with serum collectins
    • PMID: 9435570
    • Hartshorn KL, White MR, Shepherd V, Reid K, Jensenius JC, Crouch EC. Mechanisms of anti-influenza activity of surfactant proteins A and D: comparison with serum collectins. Am J Physiol. 1997; 273(6 Pt 1):L1156-66. PMID: 9435570.
    • (1997) Am J Physiol , vol.273 , Issue.6 , pp. L1156-L1166
    • Hartshorn, K.L.1    White, M.R.2    Shepherd, V.3    Reid, K.4    Jensenius, J.C.5    Crouch, E.C.6
  • 35
    • 0025129123 scopus 로고
    • Characterization of influenza A virus activation of the human neutrophil
    • PMID: 2153030
    • Hartshorn KL, Collamer M, White MR, Schwartz JH, Tauber AI. Characterization of influenza A virus activation of the human neutrophil. Blood. 1990; 75(1):218-26. PMID: 2153030
    • (1990) Blood , vol.75 , Issue.1 , pp. 218-226
    • Hartshorn, K.L.1    Collamer, M.2    White, M.R.3    Schwartz, J.H.4    Tauber, A.I.5
  • 36
    • 0034667522 scopus 로고    scopus 로고
    • Mechanism of binding of surfactant protein d to influenza a viruses: Importance of binding to haemagglutinin to antiviral activity
    • PMID: 11023831
    • Hartshorn KL, White MR, Voelker DR, Coburn J, Zaner K, Crouch EC. Mechanism of binding of surfactant protein D to influenza A viruses: importance of binding to haemagglutinin to antiviral activity. Biochem J. 2000; 351 Pt 2:449-58. PMID: 11023831.
    • (2000) Biochem J , vol.351 , pp. 449-458
    • Hartshorn, K.L.1    White, M.R.2    Voelker, D.R.3    Coburn, J.4    Zaner, K.5    Crouch, E.C.6
  • 37
    • 77954065271 scopus 로고    scopus 로고
    • I-TASSER: A unified platform for automated protein structure and function prediction
    • PMID: 20360767; PubMed Central PMCID: PMC2849174
    • Roy A, Kucukural A, Zhang Y. I-TASSER: a unified platform for automated protein structure and function prediction. Nature protocols. 2010; 5(4):725-38. doi: 10.1038/nprot.2010.5 PMID: 20360767; PubMed Central PMCID: PMC2849174.
    • (2010) Nature Protocols , vol.5 , Issue.4 , pp. 725-738
    • Roy, A.1    Kucukural, A.2    Zhang, Y.3
  • 38
    • 84884673669 scopus 로고    scopus 로고
    • Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex
    • PMID: 24030490; PubMed Central PMCID: PMC3819204
    • Tan Q, Zhu Y, Li J, Chen Z, Han GW, Kufareva I, et al. Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science. 2013; 341(6152):1387-90. doi:10.1126/science.1241475 PMID: 24030490; PubMed Central PMCID: PMC3819204.
    • (2013) Science , vol.341 , Issue.6152 , pp. 1387-1390
    • Tan, Q.1    Zhu, Y.2    Li, J.3    Chen, Z.4    Han, G.W.5    Kufareva, I.6
  • 39
    • 84893954062 scopus 로고    scopus 로고
    • Molecular control of delta-opioid receptor signalling
    • PMID: 24413399; PubMed Central PMCID: PMC3931418
    • Fenalti G, Giguere PM, Katritch V, Huang XP, Thompson AA, Cherezov V, et al. Molecular control of delta-opioid receptor signalling. Nature. 2014; 506(7487):191-6. doi:10.1038/nature12944 PMID: 24413399; PubMed Central PMCID: PMC3931418.
    • (2014) Nature , vol.506 , Issue.7487 , pp. 191-196
    • Fenalti, G.1    Giguere, P.M.2    Katritch, V.3    Huang, X.P.4    Thompson, A.A.5    Cherezov, V.6
  • 40
    • 36448995359 scopus 로고    scopus 로고
    • High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor
    • PMID: 17962520; PubMed Central PMCID: PMC2583103
    • Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, et al. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science. 2007; 318(5854):1258-65. doi: 10.1126/science.1150577 PMID: 17962520; PubMed Central PMCID: PMC2583103.
    • (2007) Science , vol.318 , Issue.5854 , pp. 1258-1265
    • Cherezov, V.1    Rosenbaum, D.M.2    Hanson, M.A.3    Rasmussen, S.G.4    Thian, F.S.5    Kobilka, T.S.6
  • 41
    • 36749031065 scopus 로고    scopus 로고
    • ClusPro: Performance in CAPRI rounds 6-11 and the new server
    • PMID: 17876812
    • Comeau SR, Kozakov D, Brenke R, Shen Y, Beglov D, Vajda S. ClusPro: performance in CAPRI rounds 6-11 and the new server. Proteins. 2007; 69(4):781-5. doi: 10.1002/prot.21795 PMID: 17876812.
    • (2007) Proteins , vol.69 , Issue.4 , pp. 781-785
    • Comeau, S.R.1    Kozakov, D.2    Brenke, R.3    Shen, Y.4    Beglov, D.5    Vajda, S.6
  • 42
    • 0025333296 scopus 로고
    • Human neutrophil stimulation by influenza virus: Relationship of cytoplasmic pH changes to cell activation
    • PMID: 2113768
    • Hartshorn KL, Wright J, Collamer MA, White MR, Tauber AI. Human neutrophil stimulation by influenza virus: relationship of cytoplasmic pH changes to cell activation. Am J Physiol. 1990; 258(6 Pt 1): C1070-6. PMID: 2113768.
    • (1990) Am J Physiol , vol.258 , Issue.6 , pp. C1070-C1076
    • Hartshorn, K.L.1    Wright, J.2    Collamer, M.A.3    White, M.R.4    Tauber, A.I.5
  • 43
    • 84908302078 scopus 로고    scopus 로고
    • LL-37 modulates human neutrophil responses to influenza A virus
    • PMID: 25082153
    • Tripathi S, Verma A, Kim EJ, White MR, Hartshorn KL. LL-37 modulates human neutrophil responses to influenza A virus. J Leukoc Biol. 2014. doi: 10.1189/jlb.4A1113-604RR PMID: 25082153.
    • (2014) J Leukoc Biol
    • Tripathi, S.1    Verma, A.2    Kim, E.J.3    White, M.R.4    Hartshorn, K.L.5
  • 44
    • 79955673539 scopus 로고    scopus 로고
    • Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1
    • PMID: 21307335
    • Wan M, Godson C, Guiry PJ, Agerberth B, Haeggstrom JZ. Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1. FASEB J. 2011; 25(5):1697-705. doi: 10.1096/fj.10-175687 PMID: 21307335.
    • (2011) FASEB J , vol.25 , Issue.5 , pp. 1697-1705
    • Wan, M.1    Godson, C.2    Guiry, P.J.3    Agerberth, B.4    Haeggstrom, J.Z.5
  • 45
    • 84875438718 scopus 로고    scopus 로고
    • The human antimicrobial peptide LL-37, but not the mouse ortholog, mCRAMP, can stimulate signaling by poly(I:C) through a FPRL1-dependent pathway
    • PMID: 23386607; PubMed Central PMCID: PMC3605644
    • Singh D, Qi R, Jordan JL, San Mateo L, Kao CC. The human antimicrobial peptide LL-37, but not the mouse ortholog, mCRAMP, can stimulate signaling by poly(I:C) through a FPRL1-dependent pathway. J Biol Chem. 2013; 288(12):8258-68. doi: 10.1074/jbc.M112.440883 PMID: 23386607; PubMed Central PMCID: PMC3605644.
    • (2013) J Biol Chem , vol.288 , Issue.12 , pp. 8258-8268
    • Singh, D.1    Qi, R.2    Jordan, J.L.3    San Mateo, L.4    Kao, C.C.5
  • 46
    • 84924059048 scopus 로고    scopus 로고
    • SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx
    • PMID: 25730848
    • Douda DN, Khan MA, Grasemann H, Palaniyar N. SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx. Proc Natl Acad Sci U S A. 2015; 112 (9):2817-22. doi: 10.1073/pnas.1414055112 PMID: 25730848.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.9 , pp. 2817-2822
    • Douda, D.N.1    Khan, M.A.2    Grasemann, H.3    Palaniyar, N.4
  • 47
    • 0027049045 scopus 로고
    • Influenza A virus binding to human neutrophils and cross-linking requirements for activation
    • PMID: 1334733
    • Daigneault DE, Hartshorn KL, Liou LS, Abbruzzi GM, White MR, Oh SK, et al. Influenza A virus binding to human neutrophils and cross-linking requirements for activation. Blood. 1992; 80(12):3227-34. PMID: 1334733.
    • (1992) Blood , vol.80 , Issue.12 , pp. 3227-3234
    • Daigneault, D.E.1    Hartshorn, K.L.2    Liou, L.S.3    Abbruzzi, G.M.4    White, M.R.5    Oh, S.K.6
  • 48
    • 0029868458 scopus 로고    scopus 로고
    • Neutrophil deactivation by influenza A viruses: Mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies
    • PMID: 8605364
    • Hartshorn KL, Reid KB, White MR, Jensenius JC, Morris SM, Tauber AI, et al. Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies. Blood. 1996; 87(8):3450-61. PMID: 8605364.
    • (1996) Blood , vol.87 , Issue.8 , pp. 3450-3461
    • Hartshorn, K.L.1    Reid, K.B.2    White, M.R.3    Jensenius, J.C.4    Morris, S.M.5    Tauber, A.I.6
  • 49
    • 84940399444 scopus 로고    scopus 로고
    • Targeting the annexin 1-formyl peptide receptor 2/ALX pathway affords protection against bacterial LPS-induced pathologic changes in the murine adrenal cortex
    • PMID: 25818588
    • Buss NA, Gavins FN, Cover PO, Terron A, Buckingham JC. Targeting the annexin 1-formyl peptide receptor 2/ALX pathway affords protection against bacterial LPS-induced pathologic changes in the murine adrenal cortex. FASEB J. 2015. doi: 10.1096/fj.14-268375 PMID: 25818588.
    • FASEB J , vol.2015
    • Buss, N.A.1    Gavins, F.N.2    Cover, P.O.3    Terron, A.4    Buckingham, J.C.5
  • 50
    • 0035178393 scopus 로고    scopus 로고
    • Receptors for chemotactic formyl peptides as pharmacological targets
    • PMID: 11789660
    • Le Y, Yang Y, Cui Y, Yazawa H, Gong W, Qiu C, et al. Receptors for chemotactic formyl peptides as pharmacological targets. Int Immunopharmacol. 2002; 2(1):1-13. PMID: 11789660.
    • (2002) Int Immunopharmacol , vol.2 , Issue.1 , pp. 1-13
    • Le Yang Y, Y.1    Cui, Y.2    Yazawa, H.3    Gong, W.4    Qiu, C.5
  • 51
    • 84928902559 scopus 로고    scopus 로고
    • Antiviral activity of the human cathelicidin LL-37 and derived peptides on seasonal and pandemic influenza A virus
    • Tripathi S, Wang G, White M, Qi L, Taubenberger J, Hartshorn K. Antiviral activity of the human cathelicidin, LL-37, and derived peptides on seasonal and pandemic influenza A virus. PLOS One. 2015; e0214706.
    • (2015) PLOS One , pp. e0214706
    • Tripathi, S.1    Wang, G.2    White, M.3    Qi, L.4    Taubenberger, J.5    Hartshorn, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.