Anti-inflamm-aging effects of long-term caloric restriction via overexpression of SIGIRR to inhibit NF-κB signaling pathway

Cellular Physiology and Biochemistry

Volumn 37, Issue 4, 2015, Pages 1257-1270

  Xu, Xiao Meng ^a   Ning, Yi Chun ^a   Wang, Wen Juan ^a   Liu, Jie Qiong ^a   Bai, Xue Yuan ^a   Sun, Xue Feng ^a   Cai, Guang Yan ^a   Chen, Xiang Mei ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Aging; Caloric restriction; Inflammation; Kidney; NF B; SIGIRR

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MYELOID DIFFERENTIATION FACTOR 88; SINGLE IMMUNOGLOBULIN INTERLEUKIN 1 RELATED RECEPTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; INTERLEUKIN 1 RECEPTOR; IRAK4 PROTEIN, RAT; PROTEIN SERINE THREONINE KINASE;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; B LYMPHOCYTE ACTIVATION; BIOCHEMICAL ANALYSIS; CALORIC RESTRICTION; CONTROLLED STUDY; FOOD INTAKE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; FISCHER 344 RAT; GENETICS; KIDNEY; METABOLISM; PATHOLOGY;

AGING; ANIMALS; CALORIC RESTRICTION; INFLAMMATION; KIDNEY; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, INBRED F344; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 4;

EID: 84943329027     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430248     Document Type: Article

References (37)

1. Franceschi C, Bonafe M, Valensin S, Olivieri F, De Luca M, Ottaviani E, De Benedictis G. Inflamm-Aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci 2000;908:244-254.
2. Franceschi C, Valensin S, Bonafe M, Paolisso G, Yashin AI, Monti D, De Benedictis G. The network and the remodeling theories of aging: Historical background and new perspectives. Exp Gerontol 2000;35:879-896.
3. Candore G, Caruso C, Colonna-Romano G. Inflammation, genetic background and longevity. Biogerontology 2010;11:565-573.
4. Boren E, Gershwin ME. Inflamm-Aging: Autoimmunity, and the immune-risk phenotype. Autoimmun Rev 2004;3:401-406.
5. Franceschi C, Valensin S, Lescai F, Olivieri F, Licastro F, Grimaldi LM, Monti D, De Benedictis G, Bonafe M. Neuroinflammation and the genetics of alzheimer's disease: The search for a pro-inflammatory phenotype. Aging 2001;13:163-170.
6. De Martinis M, Franceschi C, Monti D, Ginaldi L. Inflamm-Ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett 2005;579:2035-2039.
7. Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF. A family of human receptors structurally related to drosophila toll. Proc Natl Acad Sci USA 1998;95:588-593.
8. Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: Update on toll-like receptors. Nat Immunol 2010;11:373-384.
9. Qin J, Qian Y, Yao J, Grace C, Li X. Sigirr inhibits interleukin-1 receptor-And toll-like receptor 4-mediated signaling through different mechanisms. J Biol Chem 2005;280:25233-25241.
10. Skuginna V, Lech M, Allam R, Ryu M, Clauss S, Susanti HE, Rommele C, Garlanda C, Mantovani A, Anders HJ. Toll-like receptor signaling and sigirr in renal fibrosis upon unilateral ureteral obstruction. PLoS One 2011;6:e19204.
11. Anderson S, Brenner BM. Effects of aging on the renal glomerulus. Am J Med 1986;80:435-442.
12. Jiang T, Liebman SE, Lucia MS, Phillips CL, Levi M. Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease. J Am Soc Nephrol 2005;16:2385-2394.
13. McKiernan SH, Bua E, McGorray J, Aiken J. Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle. FASEB J 2004;18:580-581.
14. Nicoletti VG, Marino VM, Cuppari C, Licciardello D, Patti D, Purrello VS, Stella AM. Effect of antioxidant diets on mitochondrial gene expression in rat brain during aging. Neurochem Res 2005;30:737-752.
15. Ning YC, Cai GY, Zhuo L, Gao JJ, Dong D, Cui S, Feng Z, Shi SZ, Bai XY, Sun XF, Chen XM. Short-Derm calorie restriction protects against renal senescence of aged rats by increasing autophagic activity and reducing oxidative damage. Mech Ageing Dev 2013;134:570-579.
16. Cui J, Shi S, Sun X, Cai G, Cui S, Hong Q, Chen X, Bai XY. Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys. PLoS One 2013;8:e69720.
17. Csiszar A, Gautam T, Sosnowska D, Tarantini S, Banki E, Tucsek Z, Toth P, Losonczy G, Koller A, Reglodi D, Giles CB, Wren JD, Sonntag WE, Ungvari Z. Caloric restriction confers persistent anti-oxidative, pro-Angiogenic, and anti-inflammatory effects and promotes anti-Aging mirna expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol 2014;307:H292-306.
18. Mohammadi M, Ghaznavi R, Keyhanmanesh R, Sadeghipour HR, Naderi R, Mohammadi H. Caloric restriction prevents lead-induced oxidative stress and inflammation in rat liver. ScientificWorldJournal 2014;2014:821524.
19. Debelle FD, Nortier JL, De Prez EG, Garbar CH, Vienne AR, Salmon IJ, Deschodt-Lanckman MM, Vanheweghem rJL. Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats. J Am Soc Nephrol 2002;13:431-436.
20. Bazzi C. A modern approach to selectivity of proteinuria and tubulointerstitial damage in nephrotic syndrome. Kidney Int 2000;58:1732-1741.
21. Horrillo D, Sierra J, Arribas C, Carrascosa JM, Lauzurica N, Ros M. Age-Associated development of inflammation in wistar rats: Effects of caloric restriction. Arch Physiol Biochem 2011;117:140-150.
22. Gong J, Wei T, Stark RW, Jamitzky F, Heckl WM, Anders HJ, Lech M, Rossle SC. Inhibition of toll-like receptors tlr4 and 7 signaling pathways by sigirr: A computational approach. J Struct Biol 2010;169:323-330.
23. Yu BP, Chung HY. Adaptive mechanisms to oxidative stress during aging. Mech Ageing Dev 2006;127:436-443.
24. Chung HY, Sung B, Jung KJ, Zou Y, Yu BP. The molecular inflammatory process in aging. Antioxid Redox Signal 2006;8:572-581.
25. Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. Activation of innate immunity system during aging: Nf-kb signaling is the molecular culprit of inflamm-Aging. Ageing Res Rev 2008;7:83-105.
26. Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA. Calorie restriction promotes mammalian cell survival by inducing the sirt1 deacetylase. Science 2004;305:390-392.
27. Ershler WB, Keller ET. Age-Associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med 2000;51:245-270.
28. Krabbe KS, Pedersen M, Bruunsgaard H. Inflammatory mediators in the elderly. Exp Gerontol 2004;39:687-699.
29. Mark DA, Alonso DR, Quimby F, Thaler HT, Kim YT, Fernandes G, Good RA, Weksler ME. Effects of nutrition on disease and life span. I. Immune responses, cardiovascular pathology, and life span in mrl mice. Am J Pathol 1984;117:110-124.
30. Mark DA, Alonso DR, Tack-Goldman K, Thaler HT, Tremoli E, Weksler BB, Weksler ME. Effects of nutrition of disease and life span. Ii. Vascular disease, serum cholesterol, serum thromboxane, and heart-produced prostacyclin in mrl mice. Am J Pathol 1984;117:125-130.
31. Mei C, Zheng F. Chronic inflammation potentiates kidney aging. Semin Nephrol 2009;29:555-568.
32. Bakan I, Laplante M. Connecting mtorc1 signaling to srebp-1 activation. Curr Opin Lipidol 2012;23:226-234.
33. Lech M, Garlanda C, Mantovani A, Kirschning CJ, Schlondorff D, Anders HJ. Different roles of tir8/sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells. Kidney Int 2007;72:182-192.
34. Leemans JC, Butter LM, Teske GJ, Stroo I, Pulskens WP, Florquin S. The toll interleukin-1 receptor (il-1r) 8/single ig domain il-1r-related molecule modulates the renal response to bacterial infection. Infect Immun 2012;80:3812-3820.
35. Wullschleger S, Loewith R, Hall MN. Tor signaling in growth and metabolism. Cell 2006;124:471-484.
36. Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA, Sartorelli V. Glucose restriction inhibits skeletal myoblast differentiation by activating sirt1 through ampk-mediated regulation of nampt. Dev Cell 2008;14:661-673.
37. Fulco M, Sartorelli V. Comparing and contrasting the roles of ampk and sirt1 in metabolic tissues. Cell cycle 2008;7:3669-3679.