-
1
-
-
80052010923
-
Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: A trial of the ncic clinical trials group
-
Oza AM, Elit L, Tsao MS, et al. Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the ncic clinical trials group. J Clin Oncol. 2011; 29: 3278-3285.
-
(2011)
J Clin Oncol.
, vol.29
, pp. 3278-3285
-
-
Oza, A.M.1
Elit, L.2
Tsao, M.S.3
-
2
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
Motzer RJ, Escudier B, Oudard S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet. 2008; 372: 449-456.
-
(2008)
Lancet.
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
3
-
-
68949102180
-
Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma
-
Hess G, Herbrecht R, Romaguera J, et al. Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma. J Clin Oncol. 2009; 27: 3822-3829.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 3822-3829
-
-
Hess, G.1
Herbrecht, R.2
Romaguera, J.3
-
4
-
-
58249120506
-
Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance
-
Ihle NT, Lemos R Jr, Wipf P, et al. Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance. Cancer Res. 2009; 69: 143-150.
-
(2009)
Cancer Res.
, vol.69
, pp. 143-150
-
-
Ihle, N.T.1
Lemos, Jr.R.2
Wipf, P.3
-
5
-
-
57349194139
-
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
-
Engelman JA, Chen L, Tan X, et al. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med. 2008; 14: 1351-1356.
-
(2008)
Nat Med.
, vol.14
, pp. 1351-1356
-
-
Engelman, J.A.1
Chen, L.2
Tan, X.3
-
6
-
-
79956000555
-
Stathmin over expression identifies high-risk patients and lymph node metastasis in endometrial cancer
-
Torvik J, Wik E, Stefansson IM, et al. Stathmin over expression identifies high-risk patients and lymph node metastasis in endometrial cancer. Clin Cancer Res. 2011; 17: 3368-3377.
-
(2011)
Clin Cancer Res.
, vol.17
, pp. 3368-3377
-
-
Torvik, J.1
Wik, E.2
Stefansson, I.M.3
-
7
-
-
0033784805
-
Hormonal treatment of endometrial cancer
-
Emons G, Heyl W,. Hormonal treatment of endometrial cancer. J Cancer Res Clin Oncol. 2000; 126: 619-623.
-
(2000)
J Cancer Res Clin Oncol.
, vol.126
, pp. 619-623
-
-
Emons, G.1
Heyl, W.2
-
8
-
-
0033003177
-
Oral medroxyprogesterone acetate in the treatment of advanced or recurrent endometrial carcinoma: A dose-response study by the gynecologic oncology group
-
Thigpen JT, Brady MF, Alvarez RD, et al. Oral medroxyprogesterone acetate in the treatment of advanced or recurrent endometrial carcinoma: a dose-response study by the Gynecologic Oncology Group. J Clin Oncol. 1999; 17: 1736-1744. (Pubitemid 29269242)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.6
, pp. 1736-1744
-
-
Thigpen, J.T.1
Brady, M.F.2
Alvarez, R.D.3
Adelson, M.D.4
Homesley, H.D.5
Manetta, A.6
Soper, J.T.7
Given, F.T.8
-
9
-
-
0018393594
-
Treatment of advanced endometrial carcinoma with tamoxifen
-
Swenerton KD, White GW, Boyes DA,. Treatment of advanced endometrial carcinoma with tamoxifen. N Engl J Med. 1979; 301: 105. (Pubitemid 9229704)
-
(1979)
New England Journal of Medicine
, vol.301
, Issue.2
, pp. 105
-
-
Swenerton, K.D.1
Shaw, D.2
White, G.W.3
Boyes, D.A.4
-
10
-
-
50349090897
-
Recurrent endometrial carcinoma regression with the use of the aromatase inhibitor anastrozole
-
Bellone S, Shah HR, McKenney JK, et al. Recurrent endometrial carcinoma regression with the use of the aromatase inhibitor anastrozole. Am J Obstet Gynecol. 2008; 199: e7-e10.
-
(2008)
Am J Obstet Gynecol.
, vol.199
-
-
Bellone, S.1
Shah, H.R.2
McKenney, J.K.3
-
11
-
-
20844434805
-
The activity of letrozole in patients with advanced or recurrent endometrial cancer and correlation with biological markers - A study of the National Cancer Institute of Canada Clinical Trials Group
-
DOI 10.1111/j.1048-891X.2004.14419.x
-
Ma BB, Oza A, Eisenhauer E, et al. The activity of letrozole in patients with advanced or recurrent endometrial cancer and correlation with biological markers - a study of the National Cancer Institute of Canada Clinical Trials Group. Int J Gynecol Cancer. 2004; 14: 650-658. (Pubitemid 39062922)
-
(2004)
International Journal of Gynecological Cancer
, vol.14
, Issue.4
, pp. 650-658
-
-
Ma, B.B.Y.1
Oza, A.2
Eisenhauer, E.3
Stanimir, G.4
Carey, M.5
Chapman, W.6
Latta, E.7
Sidhu, K.8
Powers, J.9
Walsh, W.10
Fyles, A.11
-
12
-
-
0027933199
-
Treatment of recurrent and metastatic endometrial carcinoma with cisplatin and doxorubicin
-
Deppe G, Malviya VK, Malone JM, Christensen CW, Saunders D,. Treatment of recurrent and metastatic endometrial cancer with cisplatin and doxorubicin. Eur J Gynaecol Oncol. 1994; 15: 263-266. (Pubitemid 24247942)
-
(1994)
European Journal of Gynaecological Oncology
, vol.15
, Issue.4
, pp. 263-266
-
-
Deppe, G.1
Malviya, V.K.2
Malone, J.M.3
Christensen, C.W.4
Saunders, D.5
-
13
-
-
2942657617
-
Phase III trial of doxorubicin plus cisplatin with or without paclitaxel plus filgrastim in advanced endometrial carcinoma: A gynecologic oncology group study
-
DOI 10.1200/JCO.2004.07.184
-
Fleming GF, Brunetto VL, Cella D, et al. Phase III trial of doxorubicin plus cisplatin with or without paclitaxel plus filgrastim in advanced endometrial carcinoma: a Gynecologic Oncology Group Study. J Clin Oncol. 2004; 22: 2159-2166. (Pubitemid 41095150)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.11
, pp. 2159-2166
-
-
Fleming, G.F.1
Brunetto, V.L.2
Cella, D.3
Look, K.Y.4
Reid, G.C.5
Munkarah, A.R.6
Kline, R.7
Burger, R.A.8
Goodman, A.9
Burks, R.T.10
Mackey, D.11
-
14
-
-
16644393813
-
Significance of PTEN alterations in endometrial carcinoma: A population-based study of mutations, promoter methylation and PTEN protein expression
-
Salvesen HB, Stefansson I, Kretzschmar EI, et al. Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression. Int J Oncol. 2004; 25: 1615-1623.
-
(2004)
Int J Oncol.
, vol.25
, pp. 1615-1623
-
-
Salvesen, H.B.1
Stefansson, I.2
Kretzschmar, E.I.3
-
15
-
-
77951667289
-
Prognostic value of microsatellite instability (MSI) and PTEN expression in women with endometrial cancer: Results from studies of the NCIC Clinical Trials Group (NCIC-CTG)
-
Mackay HJ, Gallinger S, Tsao M, et al. Prognostic value of microsatellite instability (MSI) and PTEN expression in women with endometrial cancer: Results from studies of the NCIC Clinical Trials Group (NCIC-CTG). Eur J Cancer. 2010; 46: 1365-1373.
-
(2010)
Eur J Cancer.
, vol.46
, pp. 1365-1373
-
-
MacKay, H.J.1
Gallinger, S.2
Tsao, M.3
-
16
-
-
49849087494
-
Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma
-
Lu KH, Wu W, Dave B, et al. Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma. Clin Cancer Res. 2008; 14: 2543-2550.
-
(2008)
Clin Cancer Res.
, vol.14
, pp. 2543-2550
-
-
Lu, K.H.1
Wu, W.2
Dave, B.3
-
17
-
-
33750698981
-
PIK3CA and PTEN mutations in uterine endometrioid carcinoma and complex atypical hyperplasia
-
DOI 10.1158/1078-0432.CCR-06-1375
-
Hayes MP, Wang H, Espinal-Witter R, et al. PIK3CA and PTEN mutations in uterine endometrioid carcinoma and complex atypical hyperplasia. Clin Cancer Res. 2006; 12: 5932-5935. (Pubitemid 44703751)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.20 PART 1
, pp. 5932-5935
-
-
Hayes, M.P.1
Wang, H.2
Espinal-Witter, R.3
Douglas, W.4
Solomon, G.J.5
Baker, S.J.6
Ellenson, L.H.7
-
18
-
-
84863338519
-
PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
-
Janju P, Wheler JJ, Westeni S, et al. PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations. J Clin Oncol. 2012; 30: 777-782.
-
(2012)
J Clin Oncol.
, vol.30
, pp. 777-782
-
-
Janju, P.1
Wheler, J.J.2
Westeni, S.3
-
19
-
-
80053614492
-
Phase II trial of oral ridaforolimus in patients with metastatic and/or locally advanced recurrent endometrial cancer: NCIC CTG IND192 [Abstract]
-
abstract 5013.
-
Mackay H, Welch S, Tsao MS, et al. Phase II trial of oral ridaforolimus in patients with metastatic and/or locally advanced recurrent endometrial cancer: NCIC CTG IND192 [Abstract]. J Clin Oncol. 2011; 29 (suppl 15): abstract 5013.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.SUPPL. 15
-
-
MacKay, H.1
Welch, S.2
Tsao, M.S.3
-
21
-
-
0034237676
-
Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op18
-
DOI 10.1016/S0962-8924(00)01786-4, PII S0962892400017864
-
Andersen SS,. Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op18. Trends Cell Biol. 2000; 10: 261-267. (Pubitemid 30387030)
-
(2000)
Trends in Cell Biology
, vol.10
, Issue.7
, pp. 261-267
-
-
Andersen, S.S.L.1
-
22
-
-
0029811662
-
Oncoprotein 18 is a phosphorylation-responsive regulator of microtubule dynamics
-
Marklund U, Larsson N, Gradin HM, Brattsand G, Gullberg M,. Oncoprotein 18 is a phosphorylation-responsive regulator of microtubule dynamics EMBO J. 1996; 15: 5290-5298. (Pubitemid 26336212)
-
(1996)
EMBO Journal
, vol.15
, Issue.19
, pp. 5290-5298
-
-
Marklund, U.1
Larsson, N.2
Gradin, H.M.3
Brattsand, G.4
Gullberg, M.5
-
23
-
-
63849308483
-
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation
-
Salvesen HB, Carter SL, Mannelqvist M, et al. Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proc Natl Acad Sci U S A. 2009; 106: 4834-4839.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, pp. 4834-4839
-
-
Salvesen, H.B.1
Carter, S.L.2
Mannelqvist, M.3
-
24
-
-
84864764430
-
Use of mutation profiles to refine the classification of endometrial carcinomas
-
McConechy MK, Ding J, Cheang MCU, et al. Use of mutation profiles to refine the classification of endometrial carcinomas. J Pathol. 2012; 228: 20-30.
-
(2012)
J Pathol.
, vol.228
, pp. 20-30
-
-
McConechy, M.K.1
Ding, J.2
Cheang, M.C.U.3
-
25
-
-
28244490997
-
High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma
-
DOI 10.1158/0008-5472.CAN-05-2620
-
Oda K, Stokoe D, Taketani Y, et al. High frequency of co-existing mutations of PIK3CA and PTEN genes in endometrial cancer Cancer Res. 2005; 65: 10669-10673. (Pubitemid 41713332)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10669-10673
-
-
Oda, K.1
Stokoe, D.2
Taketani, Y.3
McCormick, F.4
-
26
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
-
DOI 10.1038/nm0202-128
-
Guba M, von Breitenbuch P, Steinbauer M, et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med. 2002; 8: 128-135. (Pubitemid 34155123)
-
(2002)
Nature Medicine
, vol.8
, Issue.2
, pp. 128-135
-
-
Guba, M.1
Von Breitenbuch, P.2
Steinbauer, M.3
Koehl, G.4
Flegel, S.5
Hornung, M.6
Bruns, C.J.7
Zuelke, C.8
Farkas, S.9
Anthuber, M.10
Jauch, K.-W.11
Geissler, E.K.12
-
27
-
-
79956158534
-
Evolution in endometrial cancer: Evidence from an immunohistochemical study
-
Vandenput I, Trovik J, Leunen K, et al. Evolution in endometrial cancer: evidence from an immunohistochemical study. Int J Gynecol Cancer. 2011; 21: 316-322.
-
(2011)
Int J Gynecol Cancer.
, vol.21
, pp. 316-322
-
-
Vandenput, I.1
Trovik, J.2
Leunen, K.3
-
28
-
-
84893769114
-
Intratumoral heterogeneity in high-grade serous cancers: Defining evolution of the somatic mutational landscape across spatially and temporally selected samples
-
Vancouver, Canada; October 13-16
-
McAlpine JN, Bashashati A, Ha G, et al. Intratumoral heterogeneity in high-grade serous cancers: defining evolution of the somatic mutational landscape across spatially and temporally selected samples. Proceedings of the 14th Biennial Meeting of the International Gynecologic Cancer Society, Vancouver, Canada; October 13-16, 2012; p E73.
-
(2012)
Proceedings of the 14th Biennial Meeting of the International Gynecologic Cancer Society
-
-
McAlpine, J.N.1
Bashashati, A.2
Ha, G.3
-
29
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Köhne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 2009; 360: 1408-1417.
-
(2009)
N Engl J Med.
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
-
30
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010; 363: 1693-1703.
-
(2010)
N Engl J Med.
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
31
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses HER2
-
DOI 10.1056/NEJM200103153441101
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001; 344: 783-792. (Pubitemid 32222155)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
|