Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: Clinical activity, molecular response, and biomarkers

Annals of Oncology

Volumn 23, Issue 10, 2012, Pages 2663-2670

  Seront, E ^a,b   Rottey, S ^c   Sautois, B ^d   Kerger, J ^e   D'hondt, L A ^e   Verschaeve, V ^f   Canon, J L ^f   Dopchie, C ^g   Vandenbulcke, J M ^g   Whenham, N ^h   Goeminne, J C ⁱ   Clausse, M ^j   Verhoeven, D ^g   Glorieux, P ^k   Branders, S ^b   Dupont, P ^b   Schoonjans, J ^l   Feron, O ^b   Machiels, J P ^a  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d UNIVERSITY OF LIÈGE   (Belgium)

^e UNIVERSITY HOSPITAL OF MONT GODINNE   (Belgium)

^f Grand Hopital de Charleroi   (Belgium)

^g Clinique Saint Pierre Ottignies ^*  (Belgium)

^h Clinique Saint Pierre of Ottignies   (Belgium)

ⁱ Department of Medical Oncology   (Belgium)

^j Clinique St Luc Bouge   (Belgium)

^k Clinique Saint Joseph   (Belgium)

^l Centre Hospitalier Jolimont Lobbes   (Belgium)

more..

Author keywords

Angiogenesis; Angiopoietin 1; Everolimus; Mammalian target of rapamycin; Transitional carcinoma cell

Indexed keywords

ANGIOGENIC FACTOR; ANGIOGENIN; ANGIOPOIETIN 1; ANGIOSTATIN; CXCL16 CHEMOKINE; ENDOGLIN; ENDOSTATIN; EVEROLIMUS; GELATINASE B; INSULIN GROWTH FACTOR BINDING PROTEIN 1; INSULIN GROWTH FACTOR BINDING PROTEIN 2; INSULIN GROWTH FACTOR BINDING PROTEIN 3; PENTRAXIN 3; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR AB; PLATINUM DERIVATIVE; PROLACTIN; SERINE PROTEINASE INHIBITOR; THROMBOCYTE FACTOR 4; THROMBOSPONDIN 1; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; AGED; ANEMIA; ANOREXIA; ANTIANGIOGENIC ACTIVITY; ARTICLE; BRAIN HEMORRHAGE; CANCER CONTROL; CANCER CONTROL RATE; CANCER GROWTH; CHEMOTHERAPY INDUCED NAUSEA AND VOMITING; CLINICAL ARTICLE; CLINICAL ASSESSMENT; DIARRHEA; DRUG EFFICACY; DRUG ERUPTION; DRUG SAFETY; DRUG TOLERABILITY; DRUG TREATMENT FAILURE; FATIGUE; FEMALE; GENE; GENE MUTATION; HEART INFARCTION; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; LIVER TOXICITY; MALE; METASTASIS POTENTIAL; MOLECULAR MECHANICS; MONOTHERAPY; MULTICENTER STUDY; NEUTROPENIA; ONCOLOGICAL PARAMETERS; OPEN STUDY; PHASE 2 CLINICAL TRIAL; PIK3CA GENE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; STOMATITIS; THROMBOCYTOPENIA; TRANSITIONAL CELL CARCINOMA; TREATMENT DURATION; TREATMENT RESPONSE; UROGENITAL SYSTEM;

EID: 84864369495     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mds057     Document Type: Article

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